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Results: 1-15 |
Results: 15
Differential effects of fluvoxamine and other antidepressants on the biotransformation of melatonin
Authors: Hartter, S Wang, XM Weigmann, H Friedberg, T Arand, M Oesch, F Hiemke, C
Citation: S. Hartter et al., Differential effects of fluvoxamine and other antidepressants on the biotransformation of melatonin, J CL PSYCH, 21(2), 2001, pp. 167-174
Human NADPH-P450 oxidoreductase modulates the level of cytochrome P450CYP2D6 holoprotein via haem oxygenase-dependent and -independent pathways
Authors: Ding, S Yao, D Deeni, YY Burchell, B Wolf, CR Friedberg, T
Citation: S. Ding et al., Human NADPH-P450 oxidoreductase modulates the level of cytochrome P450CYP2D6 holoprotein via haem oxygenase-dependent and -independent pathways, BIOCHEM J, 356, 2001, pp. 613-619
Engineering of a functional human NADH-dependent cytochrome P450 system
Authors: Dohr, O Paine, MJI Friedberg, T Roberts, GCK Wolf, CR
Citation: O. Dohr et al., Engineering of a functional human NADH-dependent cytochrome P450 system, P NAS US, 98(1), 2001, pp. 81-86
Modulation of P450CYP3A4-dependent metabolism by P-glycoprotein: Implications for P450 phenotyping
Authors: Baron, JM Goh, LB Yao, DG Wolf, CR Friedberg, T
Citation: Jm. Baron et al., Modulation of P450CYP3A4-dependent metabolism by P-glycoprotein: Implications for P450 phenotyping, J PHARM EXP, 296(2), 2001, pp. 351-358
Polymorphisms in P450CYP1B1 affect the conversion of estradiol to the potentially carcinogenic metabolite 4-hydroxyestradiol
Authors: Li, DN Seidel, A Pritchard, MP Wolf, CR Friedberg, T
Citation: Dn. Li et al., Polymorphisms in P450CYP1B1 affect the conversion of estradiol to the potentially carcinogenic metabolite 4-hydroxyestradiol, PHARMACOGEN, 10(4), 2000, pp. 343-353
Detoxication of vinca alkaloids by human P450CYP3A4-mediated metabolism: Implications for the development of drug resistance
Authors: Yao, DG Ding, SH Burchell, B Wolf, CR Friedberg, T
Citation: Dg. Yao et al., Detoxication of vinca alkaloids by human P450CYP3A4-mediated metabolism: Implications for the development of drug resistance, J PHARM EXP, 294(1), 2000, pp. 387-395
Mechanism-based inactivation of cytochrome P450 3A4 by L-754,394
Authors: Lightning, LK Jones, JP Friedberg, T Pritchard, MP Shou, M Rushmore, TH Trager, WF
Citation: Lk. Lightning et al., Mechanism-based inactivation of cytochrome P450 3A4 by L-754,394, BIOCHEM, 39(15), 2000, pp. 4276-4287
Amino acid 305 determines catalytic center accessibility in CYP3A4
Authors: Fowler, SM Riley, RJ Pritchard, MP Sutcliffe, MJ Friedberg, T Wolf, CR
Citation: Sm. Fowler et al., Amino acid 305 determines catalytic center accessibility in CYP3A4, BIOCHEM, 39(15), 2000, pp. 4406-4414
Merits and limitations of recombinant models for the study of human P450-mediated drug metabolism and toxicity: An intralaboratory comparison
Authors: Friedberg, T Pritchard, MP Bandera, M Hanlon, SP Yao, D McLaughlin, LA Ding, S Burchell, B Wolf, CR
Citation: T. Friedberg et al., Merits and limitations of recombinant models for the study of human P450-mediated drug metabolism and toxicity: An intralaboratory comparison, DRUG METAB, 31(2), 1999, pp. 523-544
Rapid characterization of the major drug-metabolizing human hepatic cytochrome P-450 enzymes expressed in Escherichia coli
Authors: McGinnity, DF Griffin, SJ Moody, GC Voice, M Hanlon, S Friedberg, T Riley, RJ
Citation: Df. Mcginnity et al., Rapid characterization of the major drug-metabolizing human hepatic cytochrome P-450 enzymes expressed in Escherichia coli, DRUG META D, 27(9), 1999, pp. 1017-1023
Competition between cytochrome P-450 isozymes for NADPH-cytochrome P-450 oxidoreductase affects drug metabolism
Authors: Li, DN Pritchard, MP Hanlon, SP Burchell, B Wolf, CR Friedberg, T
Citation: Dn. Li et al., Competition between cytochrome P-450 isozymes for NADPH-cytochrome P-450 oxidoreductase affects drug metabolism, J PHARM EXP, 289(2), 1999, pp. 661-667
Treatment of mammalian cells with the endoplasmic reticulum-proliferator compactin strongly induces recombinant and endogenous xenobiotic metabolizing enzymes and 3-hydroxy-3-methylglutaryl-CoA reductase in vitro
Authors: McLaughlin, L Burchell, B Pritchard, M Wolf, CR Friedberg, T
Citation: L. Mclaughlin et al., Treatment of mammalian cells with the endoplasmic reticulum-proliferator compactin strongly induces recombinant and endogenous xenobiotic metabolizing enzymes and 3-hydroxy-3-methylglutaryl-CoA reductase in vitro, J CELL SCI, 112(4), 1999, pp. 515-523
Electrospray ionization mass spectrometric analysis of intact cytochrome P450: Identification of tienilic acid adducts to P450 2C9
Authors: Koenigs, LL Peter, RM Hunter, AP Haining, RL Rettie, AE Friedberg, T Pritchard, MP Shou, M Rushmore, TH Trager, WF
Citation: Ll. Koenigs et al., Electrospray ionization mass spectrometric analysis of intact cytochrome P450: Identification of tienilic acid adducts to P450 2C9, BIOCHEM, 38(8), 1999, pp. 2312-2319
Effects of human cytochrome b(5) on CYP3A4 activity and stability in vivo
Authors: Voice, MW Zhang, Y Wolf, CR Burchell, B Friedberg, T
Citation: Mw. Voice et al., Effects of human cytochrome b(5) on CYP3A4 activity and stability in vivo, ARCH BIOCH, 366(1), 1999, pp. 116-124
In vivo and in vitro recombinant DNA technology as a powerful tool in drugdevelopment
Authors: Friedberg, T Henderson, CJ Pritchard, MP Wolf, CR
Citation: T. Friedberg et al., In vivo and in vitro recombinant DNA technology as a powerful tool in drugdevelopment, HANDBOOK OF DRUG METABOLISM, 1999, pp. 321-362
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