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Results: 1-23 |
Results: 23
Pharmacologic rescue of lethal seizures in mice deficient in succinate semialdehyde dehydrogenase
Authors: Hogema, BM Gupta, M Senephansiri, H Burlingame, TG Taylor, M Jakobs, C Schutgens, RBH Froestl, W Snead, OC Diaz-Arrastia, R Bottiglieri, T Grompe, M Gibson, KM
Citation: Bm. Hogema et al., Pharmacologic rescue of lethal seizures in mice deficient in succinate semialdehyde dehydrogenase, NAT GENET, 29(2), 2001, pp. 212-216
Epilepsy, hyperalgesia, impaired memory, and loss of pre- and postsynapticGABA(B) responses in mice lacking GABA(B(1))
Authors: Schuler, V Luscher, C Blanchet, C Klix, N Sansig, G Klebs, K Schmutz, M Heid, J Gentry, C Urban, L Fox, A Spooren, W Jaton, AL Vigouret, JM Pozza, M Kelly, PH Mosbacher, J Froestl, W Kaslin, E Korn, R Bischoff, S Kaupmann, K van der Putten, H Bettler, B
Citation: V. Schuler et al., Epilepsy, hyperalgesia, impaired memory, and loss of pre- and postsynapticGABA(B) responses in mice lacking GABA(B(1)), NEURON, 31(1), 2001, pp. 47-58
The effects of GABA(B) agonists and gabapentin on mechanical hyperalgesia in models of neuropathic and inflammatory pain in the rat
Authors: Patel, S Naeem, S Kesingland, A Froestl, W Capogna, M Urban, L Fox, A
Citation: S. Patel et al., The effects of GABA(B) agonists and gabapentin on mechanical hyperalgesia in models of neuropathic and inflammatory pain in the rat, PAIN, 90(3), 2001, pp. 217-226
C-terminal interaction is essential for surface trafficking but not for heteromeric assembly of GABA(B) receptors
Authors: Pagano, A Rovelli, G Mosbacher, J Lohmann, T Duthey, B Stauffer, D Ristig, D Schuler, V Meigel, I Lampert, C Stein, T Prezeau, L Blahos, J Pin, JP Froestl, W Kuhn, R Heid, J Kaupmann, K Bettler, B
Citation: A. Pagano et al., C-terminal interaction is essential for surface trafficking but not for heteromeric assembly of GABA(B) receptors, J NEUROSC, 21(4), 2001, pp. 1189-1202
Both GABA(B) receptor agonist and antagonists decreased brain stimulation reward in the rat
Authors: Macey, DJ Froestl, W Koob, GF Markou, A
Citation: Dj. Macey et al., Both GABA(B) receptor agonist and antagonists decreased brain stimulation reward in the rat, NEUROPHARM, 40(5), 2001, pp. 676-685
Positive allosteric modulation of native and recombinant,gamma-aminobutyric acid(B) receptors by 2,6-Di-tert-butyl-4-(3-hydroxy-2,2-dimethyl-propyl)-phenol (CGP7930) and its aldehyde analog CGP13501
Authors: Urwyler, S Mosbacher, J Lingenhoehl, K Heid, J Hofstetter, K Froestl, W Bettler, B Kaupmann, K
Citation: S. Urwyler et al., Positive allosteric modulation of native and recombinant,gamma-aminobutyric acid(B) receptors by 2,6-Di-tert-butyl-4-(3-hydroxy-2,2-dimethyl-propyl)-phenol (CGP7930) and its aldehyde analog CGP13501, MOLEC PHARM, 60(5), 2001, pp. 963-971
CGP 36216 is a selective antagonist at GABA(B) presynaptic receptors in rat brain
Authors: Ong, J Bexis, S Marino, V Parker, DAS Kerr, DIB Froestl, W
Citation: J. Ong et al., CGP 36216 is a selective antagonist at GABA(B) presynaptic receptors in rat brain, EUR J PHARM, 415(2-3), 2001, pp. 191-195
Comparative activities of the enantiomeric GABA(B) receptor agonists CGP 44532 and 44533 in central and peripheral tissues
Authors: Ong, J Bexis, S Marino, V Parker, DAS Kerr, DIB Froestl, W
Citation: J. Ong et al., Comparative activities of the enantiomeric GABA(B) receptor agonists CGP 44532 and 44533 in central and peripheral tissues, EUR J PHARM, 412(1), 2001, pp. 27-37
Determination of the GABA(B) receptor agonist CGP 44532 (3-amino-2-hydroxypropylmethylphosphinic acid) in rat plasma after pre-column derivatization by micro-high-performance liquid chromatography combined with negative electrospray tandem mass spectrometry
Authors: Blum, W Aichholz, R Ramstein, P Kuhnol, J Froestl, W Desrayaud, S
Citation: W. Blum et al., Determination of the GABA(B) receptor agonist CGP 44532 (3-amino-2-hydroxypropylmethylphosphinic acid) in rat plasma after pre-column derivatization by micro-high-performance liquid chromatography combined with negative electrospray tandem mass spectrometry, J CHROMAT B, 748(2), 2000, pp. 349-359
Ca2+ requirement for high-affinity gamma-aminobutyric acid (GABA) binding at GABA(B) receptors: Involvement of serine 269 of the GABA(B)R1 subunit
Authors: Galvez, T Urwyler, S Prezeu, L Mosbacher, J Joly, C Malitschek, B Heid, J Brabet, I Froestl, W Bettler, B Kaupmann, K Pin, JP
Citation: T. Galvez et al., Ca2+ requirement for high-affinity gamma-aminobutyric acid (GABA) binding at GABA(B) receptors: Involvement of serine 269 of the GABA(B)R1 subunit, MOLEC PHARM, 57(3), 2000, pp. 419-426
Mapping the agonist-binding site of GABA(B) type 1 subunit sheds light on the activation process of GABA(B) receptors
Authors: Galvez, T Prezeau, L Milioti, G Franek, M Joly, C Froestl, W Bettler, B Bertrand, HO Blahos, J Pin, JP
Citation: T. Galvez et al., Mapping the agonist-binding site of GABA(B) type 1 subunit sheds light on the activation process of GABA(B) receptors, J BIOL CHEM, 275(52), 2000, pp. 41166-41174
Distribution and properties of GABA(B) antagonist [H-3]CGP 62349 binding in the rhesus monkey thalamus and basal ganglia and the influence of lesionsin the reticular thalamic nucleus
Authors: Ambardekar, AV Ilinsky, IA Froestl, W Bowery, NG Kultas-Ilinsky, K
Citation: Av. Ambardekar et al., Distribution and properties of GABA(B) antagonist [H-3]CGP 62349 binding in the rhesus monkey thalamus and basal ganglia and the influence of lesionsin the reticular thalamic nucleus, NEUROSCIENC, 93(4), 1999, pp. 1339-1347
Ligands for the isolation of GABA(B) receptors (vol 38, pg 1641, 1999)
Authors: Froestl, W Bettler, B Bittiger, H Heid, J Kaupmann, K Mickel, SJ Strub, D
Citation: W. Froestl et al., Ligands for the isolation of GABA(B) receptors (vol 38, pg 1641, 1999), NEUROPHARM, 38(12), 1999, pp. 1921-1921
Ligands for the isolation of GABA(B) receptors W. Froestl would like to dedicate this work to the first GABA(B) chemist, Cr Heinrich Keberle, on the occasion of his 77th birthday.
Authors: Froestl, W Bettler, B Bittiger, H Heid, J Kaupman, K Mickel, SJ Strub, D
Citation: W. Froestl et al., Ligands for the isolation of GABA(B) receptors W. Froestl would like to dedicate this work to the first GABA(B) chemist, Cr Heinrich Keberle, on the occasion of his 77th birthday., NEUROPHARM, 38(11), 1999, pp. 1641-1646
gamma-Hydroxybutyrate is a weak agonist at recombinant GABA(B) receptors
Authors: Lingenhoehl, K Brom, R Heid, J Beck, P Froestl, W Kaupmann, K Bettler, B Mosbacher, J
Citation: K. Lingenhoehl et al., gamma-Hydroxybutyrate is a weak agonist at recombinant GABA(B) receptors, NEUROPHARM, 38(11), 1999, pp. 1667-1673
The GABA(B) agonist CGP 44532 decreases cocaine self-administration in rats: demonstration using a progressive ratio and a discrete trials procedure
Authors: Brebner, K Froestl, W Andrews, M Phelan, R Roberts, DCS
Citation: K. Brebner et al., The GABA(B) agonist CGP 44532 decreases cocaine self-administration in rats: demonstration using a progressive ratio and a discrete trials procedure, NEUROPHARM, 38(11), 1999, pp. 1797-1804
The N-terminal domain of gamma-aminobutyric acid(B) receptors is sufficient to specify agonist and antagonist binding
Authors: Malitschek, B Schweizer, C Keir, M Heid, J Froestl, W Mosbacher, J Kuhn, R Henley, J Joly, C Pin, JP Kaupmann, K Bettler, B
Citation: B. Malitschek et al., The N-terminal domain of gamma-aminobutyric acid(B) receptors is sufficient to specify agonist and antagonist binding, MOLEC PHARM, 56(2), 1999, pp. 448-454
Mutagenesis and modeling of the GABA(B) receptor extracellular domain support a Venus flytrap mechanism for ligand binding
Authors: Galvez, T Parmentier, ML Joly, C Malitschek, B Kaupmann, K Kuhn, R Bittiger, H Froestl, W Bettler, B Pin, JP
Citation: T. Galvez et al., Mutagenesis and modeling of the GABA(B) receptor extracellular domain support a Venus flytrap mechanism for ligand binding, J BIOL CHEM, 274(19), 1999, pp. 13362-13369
Pharmacological re-evaluation of a GABA(B) receptor antagonist CGP 47332A in rat brain
Authors: Ong, J Marino, V Parker, DAS Kerr, DIB Froestl, W
Citation: J. Ong et al., Pharmacological re-evaluation of a GABA(B) receptor antagonist CGP 47332A in rat brain, EUR J PHARM, 383(2), 1999, pp. 137-141
Comparative potencies of CGP 47654A and CGP 46165A as GABA(B) receptor antagonists in rat brain
Authors: Ong, J Kerr, DIB Froestl, W
Citation: J. Ong et al., Comparative potencies of CGP 47654A and CGP 46165A as GABA(B) receptor antagonists in rat brain, EUR J PHARM, 374(3), 1999, pp. 351-354
Comparison of antagonist potencies at pre- and post-synaptic GABA(B) receptors at inhibitory synapses in the CA1 region of the rat hippocampus
Authors: Pozza, MF Manuel, NA Steinmann, M Froestl, W Davies, CH
Citation: Mf. Pozza et al., Comparison of antagonist potencies at pre- and post-synaptic GABA(B) receptors at inhibitory synapses in the CA1 region of the rat hippocampus, BR J PHARM, 127(1), 1999, pp. 211-219
Human gamma-aminobutyric acid type B receptors are differentially expressed and regulate inwardly rectifying K+ channels
Authors: Kaupmann, K Schuler, V Mosbacher, J Bischoff, S Bittiger, H Heid, J Froestl, W Leonhard, S Pfaff, T Karschin, A Bettler, B
Citation: K. Kaupmann et al., Human gamma-aminobutyric acid type B receptors are differentially expressed and regulate inwardly rectifying K+ channels, P NAS US, 95(25), 1998, pp. 14991-14996
Morpholin-2-yl-phosphinic acids are potent GABA(B) receptor antagonists inrat brain
Authors: Ong, J Kerr, DIB Bittiger, H Waldmeier, PC Baumann, PA Cooke, NG Mickel, SJ Froestl, W
Citation: J. Ong et al., Morpholin-2-yl-phosphinic acids are potent GABA(B) receptor antagonists inrat brain, EUR J PHARM, 362(1), 1998, pp. 27-34
Risultati: 1-23 |