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Results: 1-17 |
Results: 17
CYCLOPENTANEDICARBOXYLIC AND TRICARBOXYLIC ACIDS AS SQUALENE SYNTHASEINHIBITORS - SYNTHESES AND EVALUATION
Authors: SHEN W GARVEY DS COHEN J STEIN H ROSENBERG SH
Citation: W. Shen et al., CYCLOPENTANEDICARBOXYLIC AND TRICARBOXYLIC ACIDS AS SQUALENE SYNTHASEINHIBITORS - SYNTHESES AND EVALUATION, Bioorganic & medicinal chemistry letters, 8(8), 1998, pp. 891-896
NITROSOTHIOL-BASED SNO-NSAIDS AS NOVEL ANTIINFLAMMATORY, ANALGESIC DRUGS WITH REDUCED GASTROINTESTINAL TOXICITY
Authors: SAHA JK SCHROEDER JD CHEN LQ SHELEKHIN TE DONG Q GARVEY DS LETTS LG TAM SW
Citation: Jk. Saha et al., NITROSOTHIOL-BASED SNO-NSAIDS AS NOVEL ANTIINFLAMMATORY, ANALGESIC DRUGS WITH REDUCED GASTROINTESTINAL TOXICITY, Gastroenterology, 114(4), 1998, pp. 1123-1123
NITROSYLATED BOVINE SERUM-ALBUMIN DERIVATIVES AS PHARMACOLOGICALLY ACTIVE NITRIC-OXIDE CONGENERS
Authors: EWING JF YOUNG DV JANERO DR GARVEY DS GRINNELL TA
Citation: Jf. Ewing et al., NITROSYLATED BOVINE SERUM-ALBUMIN DERIVATIVES AS PHARMACOLOGICALLY ACTIVE NITRIC-OXIDE CONGENERS, The Journal of pharmacology and experimental therapeutics, 283(2), 1997, pp. 947-954
STRUCTURE-ACTIVITY STUDIES ON 2-METHYL-3-(2(S)-PYRROLIDINYLMETHOXY)PYRIDINE (ABT-089) - AN ORALLY BIOAVAILABLE 3-PYRIDYL ETHER NICOTINIC ACETYLCHOLINE-RECEPTOR LIGAND WITH COGNITION-ENHANCING PROPERTIES
Authors: LIN NH GUNN DE RYTHER KB GARVEY DS DONNELLYROBERTS DL DECKER MW BRIONI JD BUCKLEY MJ RODRIGUES AD MARSH KG ANDERSON DJ BUCCAFUSCO JJ PRENDERGAST MA SULLIVAN JP WILLIAMS M ARNERIC SP HOLLADAY MW
Citation: Nh. Lin et al., STRUCTURE-ACTIVITY STUDIES ON 2-METHYL-3-(2(S)-PYRROLIDINYLMETHOXY)PYRIDINE (ABT-089) - AN ORALLY BIOAVAILABLE 3-PYRIDYL ETHER NICOTINIC ACETYLCHOLINE-RECEPTOR LIGAND WITH COGNITION-ENHANCING PROPERTIES, Journal of medicinal chemistry, 40(3), 1997, pp. 385-390
BENZYL)AMINO]CARBONYL]CYCLOBUTANE-3,4-DICARBOXYLIC ACID (A-87049) - ANOVEL POTENT SQUALENE SYNTHASE INHIBITOR
Authors: FUNG AKL BAKER WR FAKHOURY S STEIN HH COHEN J DONNER BG GARVEY DS SPINA KP ROSENBERG SH
Citation: Akl. Fung et al., BENZYL)AMINO]CARBONYL]CYCLOBUTANE-3,4-DICARBOXYLIC ACID (A-87049) - ANOVEL POTENT SQUALENE SYNTHASE INHIBITOR, Journal of medicinal chemistry, 40(14), 1997, pp. 2123-2125
REACTIVITY OF NITROGEN MONOXIDE SPECIES WITH NADH - IMPLICATIONS FOR NITRIC OXIDE-DEPENDENT POSTTRANSLATIONAL PROTEIN MODIFICATION
Authors: EWING JF JANERO DR GRINNELL TA SCHROEDER JD GARVEY DS
Citation: Jf. Ewing et al., REACTIVITY OF NITROGEN MONOXIDE SPECIES WITH NADH - IMPLICATIONS FOR NITRIC OXIDE-DEPENDENT POSTTRANSLATIONAL PROTEIN MODIFICATION, Archives of biochemistry and biophysics, 343(1), 1997, pp. 131-139
2-(ARYLOXYMETHYL)AZACYCLIC ANALOGS AS NOVEL NICOTINIC ACETYLCHOLINE-RECEPTOR (NACHR) LIGANDS
Authors: ELLIOTT RL KOPECKA H GUNN DE LIN NH GARVEY DS RYTHER KB HOLLADAY MW ANDERSON DJ CAMPBELL JE SULLIVAN JP BUCKLEY MJ GUNTHER KL ONEILL AB DECKER MW ARNERIC SP
Citation: Rl. Elliott et al., 2-(ARYLOXYMETHYL)AZACYCLIC ANALOGS AS NOVEL NICOTINIC ACETYLCHOLINE-RECEPTOR (NACHR) LIGANDS, Bioorganic & medicinal chemistry letters, 6(19), 1996, pp. 2283-2288
A-85380 [3-(2(S)-AZETIDINYLMETHOXY)PYRIDINE] - IN-VITRO PHARMACOLOGICAL PROPERTIES OF A NOVEL, HIGH-AFFINITY ALPHA-4-BETA-2 NICOTINIC ACETYLCHOLINE-RECEPTOR LIGAND
Authors: SULLIVAN JP DONNELLYROBERTS D BRIGGS CA ANDERSON DJ GOPALAKRISHNAN M PIATTONIKAPLAN M CAMPBELL JE MCKENNA DG MOLINARI E HETTINGER AM GARVEY DS WASICAK JT HOLLADAY MW WILLIAMS M ARNERIC SP
Citation: Jp. Sullivan et al., A-85380 [3-(2(S)-AZETIDINYLMETHOXY)PYRIDINE] - IN-VITRO PHARMACOLOGICAL PROPERTIES OF A NOVEL, HIGH-AFFINITY ALPHA-4-BETA-2 NICOTINIC ACETYLCHOLINE-RECEPTOR LIGAND, Neuropharmacology, 35(6), 1996, pp. 725-734
S-NITROSYLATED TISSUE-TYPE PLASMINOGEN-ACTIVATOR PROTECTS AGAINST MYOCARDIAL ISCHEMIA REPERFUSION INJURY IN CATS - ROLE OF THE ENDOTHELIUM/
Authors: DELYANI JA NOSSULI TO SCALIA R THOMAS G GARVEY DS LEFER AM
Citation: Ja. Delyani et al., S-NITROSYLATED TISSUE-TYPE PLASMINOGEN-ACTIVATOR PROTECTS AGAINST MYOCARDIAL ISCHEMIA REPERFUSION INJURY IN CATS - ROLE OF THE ENDOTHELIUM/, The Journal of pharmacology and experimental therapeutics, 279(3), 1996, pp. 1174-1180
NOVEL 3-PYRIDYL ETHERS WITH SUBNANOMOLAR AFFINITY FOR CENTRAL NEURONAL NICOTINIC ACETYLCHOLINE-RECEPTORS
Authors: ABREO MA LIN NH GARVEY DS GUNN DE HETTINGER AM WASICAK JT PAVLIK PA MARTIN YC DONNELLYROBERTS DL ANDERSON DJ SULLIVAN JP WILLIAMS M AMERIC SP HOLLADAY MW
Citation: Ma. Abreo et al., NOVEL 3-PYRIDYL ETHERS WITH SUBNANOMOLAR AFFINITY FOR CENTRAL NEURONAL NICOTINIC ACETYLCHOLINE-RECEPTORS, Journal of medicinal chemistry, 39(4), 1996, pp. 817-825
PHENYL PYRROLIDINE ANALOGS AS POTENT NICOTINIC ACETYLCHOLINE-RECEPTOR(NACHR) LIGANDS
Authors: ELLIOTT RL RYTHER KB ANDERSON DJ RASZKIEWICZ JL CAMPBELL JE SULLIVAN JP GARVEY DS
Citation: Rl. Elliott et al., PHENYL PYRROLIDINE ANALOGS AS POTENT NICOTINIC ACETYLCHOLINE-RECEPTOR(NACHR) LIGANDS, Bioorganic & medicinal chemistry letters, 5(9), 1995, pp. 991-996
A SHORT, EFFICIENT SYNTHESIS OF THE NOVEL CHOLINERGIC CHANNEL ACTIVATOR, ABT-418, FROM L-PROLINE
Authors: ELLIOTT RL KOPECKA H LIN NH HE Y GARVEY DS
Citation: Rl. Elliott et al., A SHORT, EFFICIENT SYNTHESIS OF THE NOVEL CHOLINERGIC CHANNEL ACTIVATOR, ABT-418, FROM L-PROLINE, Synthesis, (7), 1995, pp. 772-774
THE IN-VITRO HEPATIC-METABOLISM OF ABT-418, A CHOLINERGIC CHANNEL ACTIVATOR, IN RATS, DOGS, CYNOMOLGUS MONKEYS, AND HUMANS
Authors: RODRIGUES AD FERRERO JL AMANN MT ROTERT GA CEPA SP SURBER BW MACHINIST JM TICH NR SULLIVAN JP GARVEY DS FITZGERALD M ARNERIC SP
Citation: Ad. Rodrigues et al., THE IN-VITRO HEPATIC-METABOLISM OF ABT-418, A CHOLINERGIC CHANNEL ACTIVATOR, IN RATS, DOGS, CYNOMOLGUS MONKEYS, AND HUMANS, Drug metabolism and disposition, 22(5), 1994, pp. 788-798
(S)-3-METHYL-5-(1-METHYL-2-PYRROLIDINYL)ISOXAZOLE (ABT-418) - A NOVELCHOLINERGIC LIGAND WITH COGNITION-ENHANCING AND ANXIOLYTIC ACTIVITIES.1. IN-VITRO CHARACTERIZATION
Authors: ARNERIC SP SULLIVAN JP BRIGGS CA DONNELLYROBERTS D ANDERSON DJ RASZKIEWICZ JL HUGHES ML CADMAN ED ADAMS P GARVEY DS WASICAK JT WILLIAMS M
Citation: Sp. Arneric et al., (S)-3-METHYL-5-(1-METHYL-2-PYRROLIDINYL)ISOXAZOLE (ABT-418) - A NOVELCHOLINERGIC LIGAND WITH COGNITION-ENHANCING AND ANXIOLYTIC ACTIVITIES.1. IN-VITRO CHARACTERIZATION, The Journal of pharmacology and experimental therapeutics, 270(1), 1994, pp. 310-318
(S)-3-METHYL-5-(1-METHYL-2-PYRROLIDINYL)ISOXAZOLE (ABT-418) - A NOVELCHOLINERGIC LIGAND WITH COGNITION-ENHANCING AND ANXIOLYTIC ACTIVITIES.2. IN-VIVO CHARACTERIZATION
Authors: DECKER MW BRIONI JD SULLIVAN JP BUCKLEY MJ RADEK RJ RASZKIEWICZ JL KANG CH KIM DJB GIARDINA WJ WASICAK JT GARVEY DS WILLIAMS M ARNERIC SP
Citation: Mw. Decker et al., (S)-3-METHYL-5-(1-METHYL-2-PYRROLIDINYL)ISOXAZOLE (ABT-418) - A NOVELCHOLINERGIC LIGAND WITH COGNITION-ENHANCING AND ANXIOLYTIC ACTIVITIES.2. IN-VIVO CHARACTERIZATION, The Journal of pharmacology and experimental therapeutics, 270(1), 1994, pp. 319-328
NOVEL ISOXAZOLES WHICH INTERACT WITH BRAIN CHOLINERGIC CHANNEL RECEPTORS HAVE INTRINSIC COGNITIVE ENHANCING AND ANXIOLYTIC ACTIVITIES
Authors: GARVEY DS WASICAK JT DECKER MW BRIONI JD BUCKLEY MJ SULLIVAN JP CARRERA GM HOLLADAY MW ARNERIC SP WILLIAMS M
Citation: Ds. Garvey et al., NOVEL ISOXAZOLES WHICH INTERACT WITH BRAIN CHOLINERGIC CHANNEL RECEPTORS HAVE INTRINSIC COGNITIVE ENHANCING AND ANXIOLYTIC ACTIVITIES, Journal of medicinal chemistry, 37(8), 1994, pp. 1055-1059
LIGANDS FOR BRAIN CHOLINERGIC CHANNEL RECEPTORS - SYNTHESIS AND IN-VITRO CHARACTERIZATION OF NOVEL ISOXAZOLES AND ISOTHIAZOLES AS BIOISOSTERIC REPLACEMENTS FOR THE PYRIDINE RING IN NICOTINE
Authors: GARVEY DS WASICAK JT ELLIOTT RL LEBOLD SA HETTINGER AM CARRERA GM LIN NH HE Y HOLLADAY MW ANDERSON DJ CADMAN ED RASZKIEWICZ JL SULLIVAN JP ARNERIC SP
Citation: Ds. Garvey et al., LIGANDS FOR BRAIN CHOLINERGIC CHANNEL RECEPTORS - SYNTHESIS AND IN-VITRO CHARACTERIZATION OF NOVEL ISOXAZOLES AND ISOTHIAZOLES AS BIOISOSTERIC REPLACEMENTS FOR THE PYRIDINE RING IN NICOTINE, Journal of medicinal chemistry, 37(26), 1994, pp. 4455-4463
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