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Results: 1-20 |
Results: 20
MINIMAL TUMOR-NECROSIS-FACTOR RECEPTOR-BINDING PROTEIN - OPTIMUM BIOLOGICAL-ACTIVITY OF A TRUNCATED P55 SOLUBLE TUMOR-NECROSIS-FACTOR RECEPTOR IGG FUSION PROTEIN
Authors: CORCORAN AE SCALLON BJ TRINH H CHERNAJOVSKY Y GHRAYEB J FELDMANN M
Citation: Ae. Corcoran et al., MINIMAL TUMOR-NECROSIS-FACTOR RECEPTOR-BINDING PROTEIN - OPTIMUM BIOLOGICAL-ACTIVITY OF A TRUNCATED P55 SOLUBLE TUMOR-NECROSIS-FACTOR RECEPTOR IGG FUSION PROTEIN, European cytokine network, 9(3), 1998, pp. 255-262
NEUTRALIZATION OF TNF BY THE ANTIBODY CA2 REVEALS DIFFERENTIAL REGULATION OF ADHESION MOLECULE EXPRESSION ON TNF-ACTIVATED ENDOTHELIAL-CELLS
Authors: NAKADA MT TAM SH WOULFE DS CASPER KA SWERLICK RA GHRAYEB J
Citation: Mt. Nakada et al., NEUTRALIZATION OF TNF BY THE ANTIBODY CA2 REVEALS DIFFERENTIAL REGULATION OF ADHESION MOLECULE EXPRESSION ON TNF-ACTIVATED ENDOTHELIAL-CELLS, Cell adhesion and communication (Softback), 5(6), 1998, pp. 491-503
PHARMACODYNAMICS OF REOPRO (C7E3 FAB) - FREE PLASMA-LEVELS DETERMINE CLINICAL EFFICACY
Authors: WAGNER C MACE K MASCELLI MA DERITA R LANCE E WEISMAN H GHRAYEB J JORDAN R
Citation: C. Wagner et al., PHARMACODYNAMICS OF REOPRO (C7E3 FAB) - FREE PLASMA-LEVELS DETERMINE CLINICAL EFFICACY, Thrombosis and haemostasis, 1997, pp. 26-26
REDUCTION IN SERUM VEGF AND SICAM-1 ARE ASSOCIATED WITH CLINICAL-RESPONSE TO ANTI-TNF THERAPY IN PATIENTS WITH SEVERE CROHNS-DISEASE
Authors: SHEALY D MACE K DEWOODY K LEONE A DERITA R GHRAYEB J
Citation: D. Shealy et al., REDUCTION IN SERUM VEGF AND SICAM-1 ARE ASSOCIATED WITH CLINICAL-RESPONSE TO ANTI-TNF THERAPY IN PATIENTS WITH SEVERE CROHNS-DISEASE, Gastroenterology, 112(4), 1997, pp. 1090-1090
INHIBITION OF TUMOR-NECROSIS-FACTOR ACTIVITY MINIMIZES TARGET ORGAN DAMAGE IN EXPERIMENTAL AUTOIMMUNE UVEORETINITIS DESPITE QUANTITATIVELY NORMAL ACTIVATED T-CELL TRAFFIC TO THE RETINA
Authors: DICK AD MCMENAMIN PG KORNER H SCALLON BJ GHRAYEB J FORRESTER JV SEDGWICK JD
Citation: Ad. Dick et al., INHIBITION OF TUMOR-NECROSIS-FACTOR ACTIVITY MINIMIZES TARGET ORGAN DAMAGE IN EXPERIMENTAL AUTOIMMUNE UVEORETINITIS DESPITE QUANTITATIVELY NORMAL ACTIVATED T-CELL TRAFFIC TO THE RETINA, European Journal of Immunology, 26(5), 1996, pp. 1018-1025
FUNCTIONAL COMPARISONS OF DIFFERENT TUMOR-NECROSIS-FACTOR RECEPTOR IGG FUSION PROTEINS
Authors: SCALLON BJ TRINH H NEDELMAN M BRENNAN FM FELDMANN M GHRAYEB J
Citation: Bj. Scallon et al., FUNCTIONAL COMPARISONS OF DIFFERENT TUMOR-NECROSIS-FACTOR RECEPTOR IGG FUSION PROTEINS, Cytokine, 7(8), 1995, pp. 759-770
CHIMERIC ANTI-TNF-ALPHA MONOCLONAL-ANTIBODY CA2 BINDS RECOMBINANT TRANSMEMBRANE TNF-ALPHA AND ACTIVATES IMMUNE EFFECTOR FUNCTIONS
Authors: SCALLON BJ MOORE MA TRINH H KNIGHT DM GHRAYEB J
Citation: Bj. Scallon et al., CHIMERIC ANTI-TNF-ALPHA MONOCLONAL-ANTIBODY CA2 BINDS RECOMBINANT TRANSMEMBRANE TNF-ALPHA AND ACTIVATES IMMUNE EFFECTOR FUNCTIONS, Cytokine, 7(3), 1995, pp. 251-259
THE MOUSE-HUMAN CHIMERIC MONOCLONAL-ANTIBODY CA2 NEUTRALIZES TNF IN-VITRO AND PROTECTS TRANSGENIC MICE FROM CACHEXIA AND TNF LETHALITY IN-VIVO
Authors: SIEGEL SA SHEALY DJ NAKADA MT LE JM WOLFE DS PROBERT L KOLLIAS G GHRAYEB J VILCEK J DADDONA PE
Citation: Sa. Siegel et al., THE MOUSE-HUMAN CHIMERIC MONOCLONAL-ANTIBODY CA2 NEUTRALIZES TNF IN-VITRO AND PROTECTS TRANSGENIC MICE FROM CACHEXIA AND TNF LETHALITY IN-VIVO, Cytokine, 7(1), 1995, pp. 15-25
THE IMMUNOGENICITY OF THE 7E3 MURINE MONOCLONAL FAB ANTIBODY FRAGMENTVARIABLE REGION IS DRAMATICALLY REDUCED IN HUMANS BY SUBSTITUTION OF HUMAN FOR MURINE CONSTANT REGIONS
Authors: KNIGHT DM WAGNER C JORDAN R MCALEER MF DERITA R FASS DN COLLER BS WEISMAN HF GHRAYEB J
Citation: Dm. Knight et al., THE IMMUNOGENICITY OF THE 7E3 MURINE MONOCLONAL FAB ANTIBODY FRAGMENTVARIABLE REGION IS DRAMATICALLY REDUCED IN HUMANS BY SUBSTITUTION OF HUMAN FOR MURINE CONSTANT REGIONS, Molecular immunology, 32(16), 1995, pp. 1271-1281
UNIMPAIRED AUTOREACTIVE T-CELL TRAFFIC WITHIN THE CENTRAL-NERVOUS-SYSTEM DURING TUMOR-NECROSIS-FACTOR RECEPTOR-MEDIATED INHIBITION OF EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS
Authors: KORNER H GOODSALL AL LEMCKERT FA SCALLON BJ GHRAYEB J FORD AL SEDGWICK JD
Citation: H. Korner et al., UNIMPAIRED AUTOREACTIVE T-CELL TRAFFIC WITHIN THE CENTRAL-NERVOUS-SYSTEM DURING TUMOR-NECROSIS-FACTOR RECEPTOR-MEDIATED INHIBITION OF EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS, Proceedings of the National Academy of Sciences of the United Statesof America, 92(24), 1995, pp. 11066-11070
LIPOPOLYSACCHARIDE (LPS) NEUTRALIZING PEPTIDES REVEAL A LIPID A BINDING-SITE OF LPS BINDING-PROTEIN
Authors: TAYLOR AH HEAVNER G NEDELMAN M SHERRIS D BRUNT E KNIGHT D GHRAYEB J
Citation: Ah. Taylor et al., LIPOPOLYSACCHARIDE (LPS) NEUTRALIZING PEPTIDES REVEAL A LIPID A BINDING-SITE OF LPS BINDING-PROTEIN, The Journal of biological chemistry, 270(30), 1995, pp. 17934-17938
SUCCESSFUL THERAPY OF COLLAGEN-INDUCED ARTHRITIS WITH TNF RECEPTOR-IGG FUSION PROTEIN AND COMBINATION WITH ANTI-CD4
Authors: WILLIAMS RO GHRAYEB J FELDMANN M MAINI RN
Citation: Ro. Williams et al., SUCCESSFUL THERAPY OF COLLAGEN-INDUCED ARTHRITIS WITH TNF RECEPTOR-IGG FUSION PROTEIN AND COMBINATION WITH ANTI-CD4, Immunology, 84(3), 1995, pp. 433-439
TNF-ALPHA NEUTRALIZING ANTIBODY (CA2) MITIGATES POLYARTHRITIS IN TG197 AND TG5453 TRANSGENIC MICE
Authors: SHEALY D NEDELMAN M GHRAYEB J PLOWS D GEORGE K
Citation: D. Shealy et al., TNF-ALPHA NEUTRALIZING ANTIBODY (CA2) MITIGATES POLYARTHRITIS IN TG197 AND TG5453 TRANSGENIC MICE, Arthritis and rheumatism, 38(9), 1995, pp. 856-856
POTENTIAL CLINICAL RELEVANCE OF THE MECHANISM OF INHIBITION OF IMMUNEFUNCTION BY THE MOUSE-HUMAN CHIMERIC ANTI-TNF-ALPHA ANTIBODY, CA2
Authors: DALESANDRO MB KINNEY CS FREDERICK B JORDAN RE GHRAYEB J
Citation: Mb. Dalesandro et al., POTENTIAL CLINICAL RELEVANCE OF THE MECHANISM OF INHIBITION OF IMMUNEFUNCTION BY THE MOUSE-HUMAN CHIMERIC ANTI-TNF-ALPHA ANTIBODY, CA2, Arthritis and rheumatism, 38(9), 1995, pp. 1484-1484
EXPRESSION AND CHARACTERIZATION OF CM-T413, A CHIMERIC ANTI-CD4 ANTIBODY WITH IN-VITRO IMMUNOSUPPRESSIVE ACTIVITY
Authors: LOONEY JE WILLINGER A LIN G RIEBER EP RIETHMULLER G GHRAYEB J
Citation: Je. Looney et al., EXPRESSION AND CHARACTERIZATION OF CM-T413, A CHIMERIC ANTI-CD4 ANTIBODY WITH IN-VITRO IMMUNOSUPPRESSIVE ACTIVITY, Journal of immunotherapy with emphasis on tumor immunology, 16(1), 1994, pp. 36-46
TNF RECEPTOR FUSION PROTEINS ARE EFFECTIVE INHIBITORS OF TNF-MEDIATEDCYTOTOXICITY ON HUMAN KYM-1D4 RHABDOMYOSARCOMA CELLS
Authors: BUTLER DM SCALLON B MEAGER A KISSONERGHIS M CORCORAN A CHERNAJOVSKY Y FELDMANN M GHRAYEB J BRENNAN FM
Citation: Dm. Butler et al., TNF RECEPTOR FUSION PROTEINS ARE EFFECTIVE INHIBITORS OF TNF-MEDIATEDCYTOTOXICITY ON HUMAN KYM-1D4 RHABDOMYOSARCOMA CELLS, Cytokine, 6(6), 1994, pp. 616-623
HOMOLOGOUS SELECTIN PEPTIDES BLOCK NEUTROPHIL ADHESION IN-VITRO
Authors: TAM SH NAKADA MT HEAVNER GA WEBER R KRUSZYNSKI M GHRAYEB J
Citation: Sh. Tam et al., HOMOLOGOUS SELECTIN PEPTIDES BLOCK NEUTROPHIL ADHESION IN-VITRO, Journal of cellular biochemistry, 1994, pp. 299-299
CONSTRUCTION AND INITIAL CHARACTERIZATION OF A MOUSE-HUMAN CHIMERIC ANTI-TNF ANTIBODY
Authors: KNIGHT DM TRINH H LE JM SIEGEL S SHEALY D MCDONOUGH M SCALLON B MOORE MA VILCEK J DADDONA P GHRAYEB J
Citation: Dm. Knight et al., CONSTRUCTION AND INITIAL CHARACTERIZATION OF A MOUSE-HUMAN CHIMERIC ANTI-TNF ANTIBODY, Molecular immunology, 30(16), 1993, pp. 1443-1453
NEF PROTEIN OF HIV-1 HAS B-CELL STIMULATORY ACTIVITY
Authors: CHIRMULE N OYAIZU N SAXINGER C GHRAYEB J PAHWA S
Citation: N. Chirmule et al., NEF PROTEIN OF HIV-1 HAS B-CELL STIMULATORY ACTIVITY, The Journal of immunology, 150(8), 1993, pp. 242-242
TREATMENT OF RHEUMATOID-ARTHRITIS WITH CHIMERIC MONOCLONAL-ANTIBODIESTO TUMOR-NECROSIS-FACTOR-ALPHA
Authors: ELLIOTT MJ MAINI RN FELDMANN M LONGFOX A CHARLES P KATSIKIS P BRENNAN FM WALKER J BIJL H GHRAYEB J WOODY JN
Citation: Mj. Elliott et al., TREATMENT OF RHEUMATOID-ARTHRITIS WITH CHIMERIC MONOCLONAL-ANTIBODIESTO TUMOR-NECROSIS-FACTOR-ALPHA, Arthritis and rheumatism, 36(12), 1993, pp. 1681-1690
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