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Results: 1-25 | 26-50 | 51-75 | 76-92
Results: 1-25/92
MULTIDRUG ABC TRANSPORTERS FROM BACTERIA TO MAN - AN EMERGING HYPOTHESIS FOR THE UNIVERSALITY OF MOLECULAR MECHANISM AND FUNCTION
Authors: HRYCYNA CA GOTTESMAN MM
Citation: Ca. Hrycyna et Mm. Gottesman, MULTIDRUG ABC TRANSPORTERS FROM BACTERIA TO MAN - AN EMERGING HYPOTHESIS FOR THE UNIVERSALITY OF MOLECULAR MECHANISM AND FUNCTION, DRUG RESISTANCE UPDATES, 1(2), 1998, pp. 81-83
EFFICIENT TRANSDUCTION OF HUMAN HEMATOPOIETIC-CELLS WITH THE HUMAN MULTIDRUG-RESISTANCE GENE-1 VIA SV40 PSEUDOVIRIONS
Authors: RUND D DAGAN M DALYOTHERMAN N KIMCHISARFATY C SCHOENLEIN PV GOTTESMAN MM OPPENHEIM A
Citation: D. Rund et al., EFFICIENT TRANSDUCTION OF HUMAN HEMATOPOIETIC-CELLS WITH THE HUMAN MULTIDRUG-RESISTANCE GENE-1 VIA SV40 PSEUDOVIRIONS, Human gene therapy, 9(5), 1998, pp. 649-657
COEXPRESSION OF HUMAN ADENOSINE-DEAMINASE AND MULTIDRUG-RESISTANCE USING A BICISTRONIC RETROVIRAL VECTOR
Authors: ZHOU Y ARAN J GOTTESMAN MM PASTAN I
Citation: Y. Zhou et al., COEXPRESSION OF HUMAN ADENOSINE-DEAMINASE AND MULTIDRUG-RESISTANCE USING A BICISTRONIC RETROVIRAL VECTOR, Human gene therapy, 9(3), 1998, pp. 287-293
CHARACTERIZATION OF AN MDR1 RETROVIRAL BICISTRONIC VECTOR FOR CORRECTION OF X-LINKED SEVERE COMBINED IMMUNODEFICIENCY
Authors: KLEIMAN SE PASTAN I PUCK JM GOTTESMAN MM
Citation: Se. Kleiman et al., CHARACTERIZATION OF AN MDR1 RETROVIRAL BICISTRONIC VECTOR FOR CORRECTION OF X-LINKED SEVERE COMBINED IMMUNODEFICIENCY, Gene therapy, 5(5), 1998, pp. 671-676
CONSTRUCTION AND CHARACTERIZATION OF BICISTRONIC RETROVIRAL VECTORS ENCODING THE MULTIDRUG TRANSPORTER AND BETA-GALACTOSIDASE OR GREEN FLUORESCENT PROTEIN
Authors: ARAN JM GOTTESMAN MM PASTAN I
Citation: Jm. Aran et al., CONSTRUCTION AND CHARACTERIZATION OF BICISTRONIC RETROVIRAL VECTORS ENCODING THE MULTIDRUG TRANSPORTER AND BETA-GALACTOSIDASE OR GREEN FLUORESCENT PROTEIN, Cancer gene therapy, 5(4), 1998, pp. 195-206
MOLECULAR DISSECTION OF THE MULTIDRUG TRANSPORTER
Authors: GOTTESMAN MM HRYCYNA CA HAFKEMEYER P DEY S ZHOU Y SHOSHANI T PASTAN I
Citation: Mm. Gottesman et al., MOLECULAR DISSECTION OF THE MULTIDRUG TRANSPORTER, Naunyn-Schmiedeberg's archives of pharmacology, 358(1), 1998, pp. 21-21
ANALYSIS OF RANDOM RECOMBINATION BETWEEN HUMAN MDR1 AND MOUSE MDR1A CDNA IN A PHAMDR-DIHYDROFOLATE REDUCTASE BICISTRONIC EXPRESSION SYSTEM
Authors: SHOSHANI T ZHANG SD DEY S PASTAN I GOTTESMAN MM
Citation: T. Shoshani et al., ANALYSIS OF RANDOM RECOMBINATION BETWEEN HUMAN MDR1 AND MOUSE MDR1A CDNA IN A PHAMDR-DIHYDROFOLATE REDUCTASE BICISTRONIC EXPRESSION SYSTEM, Molecular pharmacology, 54(4), 1998, pp. 623-630
HIV-1 PROTEASE INHIBITORS AND THE MDR1 MULTIDRUG TRANSPORTER
Authors: LEE CGL GOTTESMAN MM
Citation: Cgl. Lee et Mm. Gottesman, HIV-1 PROTEASE INHIBITORS AND THE MDR1 MULTIDRUG TRANSPORTER, The Journal of clinical investigation, 101(2), 1998, pp. 287-288
MECHANISM OF ACTION OF HUMAN P-GLYCOPROTEIN ATPASE ACTIVITY - PHOTOCHEMICAL CLEAVAGE DURING A CATALYTIC TRANSITION-STATE USING ORTHOVANADATE REVEALS CROSS-TALK BETWEEN THE 2 ATP SITES
Authors: HRYCYNA CA RAMACHANDRA M AMBUDKAR SV KO YH PEDERSEN PL PASTAN I GOTTESMAN MM
Citation: Ca. Hrycyna et al., MECHANISM OF ACTION OF HUMAN P-GLYCOPROTEIN ATPASE ACTIVITY - PHOTOCHEMICAL CLEAVAGE DURING A CATALYTIC TRANSITION-STATE USING ORTHOVANADATE REVEALS CROSS-TALK BETWEEN THE 2 ATP SITES, The Journal of biological chemistry, 273(27), 1998, pp. 16631-16634
P-GLYCOPROTEIN PLAYS AN INSIGNIFICANT ROLE IN THE PRESENTATION OF ANTIGENIC PEPTIDES TO CD8-CELLS( T)
Authors: RUSS G RAMACHANDRA M HRYCYNA CA GOTTESMAN MM PASTAN I BENNINK JR YEWDELL JW
Citation: G. Russ et al., P-GLYCOPROTEIN PLAYS AN INSIGNIFICANT ROLE IN THE PRESENTATION OF ANTIGENIC PEPTIDES TO CD8-CELLS( T), Cancer research, 58(20), 1998, pp. 4688-4693
CROSS-RESISTANCE TO METHOTREXATE AND METALS IN HUMAN CISPLATIN-RESISTANT CELL-LINES RESULTS FROM A PLEIOTROPIC DEFECT IN ACCUMULATION OF THESE COMPOUNDS ASSOCIATED WITH REDUCED PLASMA-MEMBRANE BINDING-PROTEINS
Authors: SHEN DW PASTAN I GOTTESMAN MM
Citation: Dw. Shen et al., CROSS-RESISTANCE TO METHOTREXATE AND METALS IN HUMAN CISPLATIN-RESISTANT CELL-LINES RESULTS FROM A PLEIOTROPIC DEFECT IN ACCUMULATION OF THESE COMPOUNDS ASSOCIATED WITH REDUCED PLASMA-MEMBRANE BINDING-PROTEINS, Cancer research, 58(2), 1998, pp. 268-275
CONTRIBUTION TO SUBSTRATE-SPECIFICITY AND TRANSPORT OF NONCONSERVED RESIDUES IN TRANSMEMBRANE DOMAIN-12 OF HUMAN P-GLYCOPROTEIN
Authors: HAFKEMEYER P DEY S AMBUDKAR SV HRYCYNA CA PASTAN I GOTTESMAN MM
Citation: P. Hafkemeyer et al., CONTRIBUTION TO SUBSTRATE-SPECIFICITY AND TRANSPORT OF NONCONSERVED RESIDUES IN TRANSMEMBRANE DOMAIN-12 OF HUMAN P-GLYCOPROTEIN, Biochemistry (Easton), 37(46), 1998, pp. 16400-16409
STRUCTURAL FLEXIBILITY OF THE LINKER REGION OF HUMAN P-GLYCOPROTEIN PERMITS ATP HYDROLYSIS AND DRUG TRANSPORT
Authors: HRYCYNA CA AIRAN LE GERMANN UA AMBUDKAR SV PASTAN I GOTTESMAN MM
Citation: Ca. Hrycyna et al., STRUCTURAL FLEXIBILITY OF THE LINKER REGION OF HUMAN P-GLYCOPROTEIN PERMITS ATP HYDROLYSIS AND DRUG TRANSPORT, Biochemistry (Easton), 37(39), 1998, pp. 13660-13673
INVOLVEMENT OF CARBOXY-TERMINAL AMINO-ACIDS IN SECRETION OF HUMAN LYSOSOMAL PROTEASE CATHEPSIN-L
Authors: CHAUHAN SS RAY D KANE SE WILLINGHAM MC GOTTESMAN MM
Citation: Ss. Chauhan et al., INVOLVEMENT OF CARBOXY-TERMINAL AMINO-ACIDS IN SECRETION OF HUMAN LYSOSOMAL PROTEASE CATHEPSIN-L, Biochemistry, 37(23), 1998, pp. 8584-8594
HUMAN P-GLYCOPROTEIN EXHIBITS REDUCED AFFINITY FOR SUBSTRATES DURING A CATALYTIC TRANSITION-STATE
Authors: RAMACHANDRA M AMBUDKAR SV CHEN D HRYCYNA CA DEY S GOTTESMAN MM PASTAN I
Citation: M. Ramachandra et al., HUMAN P-GLYCOPROTEIN EXHIBITS REDUCED AFFINITY FOR SUBSTRATES DURING A CATALYTIC TRANSITION-STATE, Biochemistry, 37(14), 1998, pp. 5010-5019
HIV-1 PROTEASE INHIBITORS ARE SUBSTRATES FOR THE MDR1 MULTIDRUG TRANSPORTER
Authors: LEE CGL GOTTESMAN MM CARDARELLI CO RAMACHANDRA M JEANG KT AMBUDKAR SV PASTAN I DEY S
Citation: Cgl. Lee et al., HIV-1 PROTEASE INHIBITORS ARE SUBSTRATES FOR THE MDR1 MULTIDRUG TRANSPORTER, Biochemistry, 37(11), 1998, pp. 3594-3601
EFFICIENT LONG-TERM COEXPRESSION OF A HAMMERHEAD RIBOZYME TARGETED TOTHE U5 REGION OF HIV-1 LTR BY LINKAGE TO THE MULTIDRUG-RESISTANCE GENE
Authors: LEE CGL JEANG KT MARTIN MA PASTAN I GOTTESMAN MM
Citation: Cgl. Lee et al., EFFICIENT LONG-TERM COEXPRESSION OF A HAMMERHEAD RIBOZYME TARGETED TOTHE U5 REGION OF HIV-1 LTR BY LINKAGE TO THE MULTIDRUG-RESISTANCE GENE, ANTISENSE & NUCLEIC ACID DRUG DEVELOPMENT, 7(5), 1997, pp. 511-522
RETROVIRAL COEXPRESSION OF 2 DIFFERENT TYPES OF DRUG-RESISTANCE GENESTO PROTECT NORMAL-CELLS FROM COMBINATION CHEMOTHERAPY
Authors: SUZUKI M SUGIMOTO Y TSUKAHARA S OKOCHI E GOTTESMAN MM TSURUO T
Citation: M. Suzuki et al., RETROVIRAL COEXPRESSION OF 2 DIFFERENT TYPES OF DRUG-RESISTANCE GENESTO PROTECT NORMAL-CELLS FROM COMBINATION CHEMOTHERAPY, Clinical cancer research, 3(6), 1997, pp. 947-954
IN-VIVO DRUG-SELECTABLE GENES - A NEW CONCEPT IN GENE-THERAPY
Authors: LICHT T HERRMANN F GOTTESMAN MM PASTAN I
Citation: T. Licht et al., IN-VIVO DRUG-SELECTABLE GENES - A NEW CONCEPT IN GENE-THERAPY, Stem cells, 15(2), 1997, pp. 104-111
DNA-PKCS - A T-CELL TUMOR-SUPPRESSOR ENCODED AT THE MOUSE SCID LOCUS
Authors: JHAPPAN C MORSE HC FLEISCHMANN RD GOTTESMAN MM MERLINO G
Citation: C. Jhappan et al., DNA-PKCS - A T-CELL TUMOR-SUPPRESSOR ENCODED AT THE MOUSE SCID LOCUS, Nature genetics, 17(4), 1997, pp. 483-486
FUNCTIONAL-CHARACTERIZATION OF HUMAN P-GLYCOPROTEIN - EVIDENCE FOR THE NON-EQUIVALENCY OF THE 2 ATP BINDING DOMAINS
Authors: HRYCYNA CA RAMACHANDRA M PASTAN I GOTTESMAN MM
Citation: Ca. Hrycyna et al., FUNCTIONAL-CHARACTERIZATION OF HUMAN P-GLYCOPROTEIN - EVIDENCE FOR THE NON-EQUIVALENCY OF THE 2 ATP BINDING DOMAINS, Molecular biology of the cell, 8, 1997, pp. 1107-1107
PHOTOAFFINITY-LABELING OF HUMAN P-GLYCOPROTEIN - EVIDENCE FOR 2 NONIDENTICAL DRUG-INTERACTION SITES
Authors: DEY S RAMACHANDRA M PASTAN I GOTTESMAN MM AMBUDKAR SV
Citation: S. Dey et al., PHOTOAFFINITY-LABELING OF HUMAN P-GLYCOPROTEIN - EVIDENCE FOR 2 NONIDENTICAL DRUG-INTERACTION SITES, Molecular biology of the cell, 8, 1997, pp. 1108-1108
COEXPRESSION OF A MULTIDRUG-RESISTANCE GENE (MDR1) AND HERPES-SIMPLEXVIRUS THYMIDINE KINASE GENE IN A BICISTRONIC RETROVIRAL VECTOR HA-MDR-IRES-TK ALLOWS SELECTIVE KILLING OF MDR1-TRANSDUCED HUMAN TUMORS TRANSPLANTED IN NUDE-MICE
Authors: SUGIMOTO Y SATO S TSUKAHARA S SUZUKI M OKOCHI E GOTTESMAN MM PASTAN I TSURUO T
Citation: Y. Sugimoto et al., COEXPRESSION OF A MULTIDRUG-RESISTANCE GENE (MDR1) AND HERPES-SIMPLEXVIRUS THYMIDINE KINASE GENE IN A BICISTRONIC RETROVIRAL VECTOR HA-MDR-IRES-TK ALLOWS SELECTIVE KILLING OF MDR1-TRANSDUCED HUMAN TUMORS TRANSPLANTED IN NUDE-MICE, Cancer gene therapy, 4(1), 1997, pp. 51-58
ALPHA-GALACTOSIDASE A DEFICIENT MICE - A MODEL OF FABRY DISEASE
Authors: OHSHIMA T MURRAY GJ SWAIM WD LONGENECKER G QUIRK JM CARDARELLI CO SUGIMOTO Y PASTAN I GOTTESMAN MM BRADY RO KULKARNI AB
Citation: T. Ohshima et al., ALPHA-GALACTOSIDASE A DEFICIENT MICE - A MODEL OF FABRY DISEASE, Proceedings of the National Academy of Sciences of the United Statesof America, 94(6), 1997, pp. 2540-2544
EVIDENCE FOR 2 NONIDENTICAL DRUG-INTERACTION SITES IN THE HUMAN P-GLYCOPROTEIN
Authors: DEY S RAMACHANDRA M PASTAN I GOTTESMAN MM AMBUDKAR SV
Citation: S. Dey et al., EVIDENCE FOR 2 NONIDENTICAL DRUG-INTERACTION SITES IN THE HUMAN P-GLYCOPROTEIN, Proceedings of the National Academy of Sciences of the United Statesof America, 94(20), 1997, pp. 10594-10599
Risultati: 1-25 | 26-50 | 51-75 | 76-92