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Results: 1-25/58
Authors:
Verlinde, CLM
Hannaert, V
Blonski, C
Willson, M
Perie, JJ
Fothergill-Gilmore, LA
Opperdoes, FR
Gelb, MH
Hol, WGJ
Michels, PAM
Citation: Clm. Verlinde et al., Glycolysis as a target for the design of new anti-trypanosome drugs, DRUG RESIST, 4(1), 2001, pp. 50-65
Authors:
Gerber, SA
Turecek, F
Gelb, MH
Citation: Sa. Gerber et al., Design and synthesis of substrate and internal standard conjugates for profiling enzyme activity in the Sanfilippo syndrome by affinity chromatography/electrospray ionization mass spectrometry, BIOCONJ CHE, 12(4), 2001, pp. 603-615
Authors:
Ohkanda, J
Lockman, JW
Yokoyama, K
Gelb, MH
Croft, SL
Kendrick, H
Harrell, MI
Feagin, JE
Blaskovich, MA
Sebti, SM
Hamilton, AD
Citation: J. Ohkanda et al., Peptidomimetic inhibitors of protein farnesyltransferase show potent antimalarial activity, BIOORG MED, 11(6), 2001, pp. 761-764
Authors:
Kennedy, KJ
Bressi, JC
Gelb, MH
Citation: Kj. Kennedy et al., A disubstituted NAD(+) analogue is a nanomolar inhibitor of trypanosomal glyceraldehyde-3-phosphate dehydrogenase, BIOORG MED, 11(2), 2001, pp. 95-98
Authors:
Goldstein, AS
Gelb, MH
Yager, P
Citation: As. Goldstein et al., Continuous and highly variable rate controlled release of model drugs fromsphingolipid-based complex high axial ratio microstructures, J CONTR REL, 70(1-2), 2001, pp. 125-138
Authors:
Suresh, S
Bressi, JC
Kennedy, KJ
Verlinde, CLMJ
Gelb, MH
Hol, WGJ
Citation: S. Suresh et al., Conformational changes in Leishmania mexicana glyceraldehyde-3-phosphate dehydrogenase induced by designed inhibitors, J MOL BIOL, 309(2), 2001, pp. 423-435
Authors:
Bressi, JC
Verlinde, CLMJ
Aronov, AM
Le Shaw, M
Shin, SS
Nguyen, LN
Suresh, S
Buckner, FS
Van Voorhis, WC
Kuntz, ID
Hol, WGJ
Gelb, MH
Citation: Jc. Bressi et al., Adenosine analogues as selective inhibitors of glyceraldehyde-3-phosphate dehydrogenase of Trypanosomatidae via structure-based drug design, J MED CHEM, 44(13), 2001, pp. 2080-2093
Authors:
Schadow, A
Scholz-Pedretti, K
Lambeau, G
Gelb, MH
Furstenberger, G
Pfeilschifter, J
Kaszkin, M
Citation: A. Schadow et al., Characterization of group X phospholipase A(2) as the major enzyme secreted by human keratinocytes and its regulation by the phorbol ester TPA, J INVES DER, 116(1), 2001, pp. 31-39
Authors:
Cook, TA
Ghomashchi, F
Gelb, MH
Florio, SK
Beavo, JA
Citation: Ta. Cook et al., The delta subunit of type 6 phosphodiesterase reduces light-induced cGMP hydrolysis in rod outer segments, J BIOL CHEM, 276(7), 2001, pp. 5248-5255
Authors:
Muthalif, MM
Hefner, Y
Canaan, S
Harper, J
Zhou, HL
Parmentier, JH
Aebersold, R
Gelb, MH
Malik, KU
Citation: Mm. Muthalif et al., Functional interaction of calcium-/calmodulin-dependent protein kinase II and cytosolic phospholipase A(2), J BIOL CHEM, 276(43), 2001, pp. 39653-39660
Authors:
Nepomuceno-Silva, JL
Yokoyama, K
de Mello, LDB
Mendonca, SM
Paixao, JC
Baron, R
Faye, JC
Buckner, FS
Van Voorhis, WC
Gelb, MH
Lopes, UG
Citation: Jl. Nepomuceno-silva et al., TcRho1, a farnesylated Rho family homologue from Trypanosoma cruzi, J BIOL CHEM, 276(32), 2001, pp. 29711-29718
Authors:
Jang, GF
Kuksa, V
Filipek, S
Bartl, F
Ritter, E
Gelb, MH
Hofmann, KP
Palczewski, K
Citation: Gf. Jang et al., Mechanism of rhodopsin activation as examined with ring-constrained retinal analogs and the crystal structure of the ground state protein, J BIOL CHEM, 276(28), 2001, pp. 26148-26153
Authors:
Yokoyama, K
Trobridge, P
Buckner, FS
Van Voorhis, WC
Stuart, KD
Gelb, MH
Citation: K. Yokoyama et al., Protein farnesyltransferase from Trypanosoma brucei. A heterodimer of 61- and 65-kDa subunits as a new target for antiparasite therapeutics (vol 273,pg 26497, 1998), J BIOL CHEM, 276(25), 2001, pp. 23212-23212
Authors:
Murakami, M
Koduri, RS
Enomoto, A
Shimbara, S
Seki, M
Yoshihara, K
Singer, A
Valentin, E
Ghomashchi, F
Lambeau, G
Gelb, MH
Kudo, I
Citation: M. Murakami et al., Distinct arachidonate-releasing functions of mammalian secreted phospholipase A(2)s in human embryonic kidney 293 and rat mastocytoma RBL-2H3 cells through heparan sulfate shuttling and external plasma membrane mechanisms, J BIOL CHEM, 276(13), 2001, pp. 10083-10096
Authors:
Zhou, XF
Turecek, F
Scott, CR
Gelb, MH
Citation: Xf. Zhou et al., Quantification of cellular acid sphingomyelinase and galactocerebroside beta-galactosidase activities by electrospray ionization mass spectrometry, CLIN CHEM, 47(5), 2001, pp. 874-881
Authors:
Goldstein, AS
Gelb, MH
Yager, P
Citation: As. Goldstein et al., The relationship between the structure of the headgroup of sphingolipids and their ability to form complex high axial ratio microstructures, CHEM PHYS L, 109(1), 2001, pp. 1-14
Authors:
Berg, OG
Gelb, MH
Tsai, MD
Jain, MK
Citation: Og. Berg et al., Interfacial enzymology: The secreted phospholipase A(2)-paradigm, CHEM REV, 101(9), 2001, pp. 2613-2653
Authors:
Min, JH
Wilder, C
Aoki, J
Arai, K
Inoue, K
Paul, L
Gelb, MH
Citation: Jh. Min et al., Platelet-activating factor acetylhydrolases: Broad substrate specificity and lipoprotein binding does not modulate the catalytic properties of the plasma enzyme, BIOCHEM, 40(15), 2001, pp. 4539-4549
Authors:
Ghomashchi, F
Stewart, A
Hefner, Y
Ramanadham, S
Turk, J
Leslie, CC
Gelb, MH
Citation: F. Ghomashchi et al., A pyrrolidine-based specific inhibitor of cytosolic phospholipase A(2)alpha blocks arachidonic acid release in a variety of mammalian cells, BBA-BIOMEMB, 1513(2), 2001, pp. 160-166
Authors:
Gerber, SA
Scott, CR
Turecek, F
Gelb, MH
Citation: Sa. Gerber et al., Direct profiling of multiple enzyme activities in human cell lysates by affinity chromatography/electrospray ionization mass spectrometry: Application to clinical enzymology, ANALYT CHEM, 73(8), 2001, pp. 1651-1657
Authors:
Gelb, MH
Buckner, FS
Yokoyama, K
Ohkanda, J
Hamilton, AD
Nguyen, L
Rossi-Bergmann, B
Stuart, KD
Sebti, SM
Van Voorhis, WC
Citation: Mh. Gelb et al., Protein prenylation in trypanosomatids - A new piggy-back medicinal chemistry target for the development of agents against tropical diseases, CANC DRUG, 8, 2001, pp. 221-232
Authors:
Golisade, A
Bressi, JC
Van Calenbergh, S
Gelb, MH
Link, A
Citation: A. Golisade et al., Polymer-assisted solution-phase synthesis of 2 '-amido-2 '-deoxyadenosine derivatives targeted at the NAD(+)-binding sites of parasite enzymes, J COMB CHEM, 2(5), 2000, pp. 537-544
Authors:
Gelb, MH
Min, JH
Jain, MK
Citation: Mh. Gelb et al., Do membrane-bound enzymes access their substrates from the membrane or aqueous phase: interfacial versus non-interfacial enzymes, BBA-MOL C B, 1488(1-2), 2000, pp. 20-27
Authors:
Whitten, ME
Yokoyama, K
Schieltz, D
Ghomashchi, F
Lam, D
Yates, JR
Palczewski, K
Gelb, MH
Citation: Me. Whitten et al., Structural analysis of protein prenyl groups and associated C-terminal modifications, METH ENZYM, 316, 2000, pp. 436-451
Authors:
Goldstein, AS
Gelb, MH
Citation: As. Goldstein et Mh. Gelb, An alternate preparation of thioester resin linkers for solid-phase synthesis of peptide C-terminal thioacids, TETRAHEDR L, 41(16), 2000, pp. 2797-2800