Citation: Ma. Giembycz, Cilomilast: a second generation phosphodiesterase 4 inhibitor for asthma and chronic obstructive pulmonary disease, EXPERT OP I, 10(7), 2001, pp. 1361-1379
Authors:
Staples, KJ
Bergmann, M
Tomita, K
Houslay, MD
McPhee, I
Barnes, PJ
Giembycz, MA
Newton, R
Citation: Kj. Staples et al., Adenosine 3 ',5 '-cyclic monophosphate (cAMP)-dependent inhibition of IL-5from human T lymphocytes is not mediated by the cAMP-dependent protein kinase A(1), J IMMUNOL, 167(4), 2001, pp. 2074-2080
Authors:
Lynch, OT
Giembycz, MA
Barnes, PJ
Lindsay, MA
Citation: Ot. Lynch et al., Pharmacological comparison of LTB4-induced NADPH oxidase activation in adherent and non-adherent guinea-pig eosinophils, BR J PHARM, 134(4), 2001, pp. 797-806
Citation: Pm. Seldon et Ma. Giembycz, Suppression of granulocyte/macrophage colony-stimulating factor release from human monocytes by cyclic AMP-elevating drugs: role of interleukin-10, BR J PHARM, 134(1), 2001, pp. 58-67
Authors:
Spicuzza, L
Belvisi, MG
Birrell, MA
Barnes, PJ
Hele, DJ
Giembycz, MA
Citation: L. Spicuzza et al., Evidence that the anti-spasmogenic effect of the beta-adrenoceptor agonist, isoprenaline, on guinea-pig trachealis is not mediated by cyclic AMP-dependent protein kinase, BR J PHARM, 133(8), 2001, pp. 1201-1212
Authors:
Finney, PA
Donnelly, LE
Belvisi, MG
Chuang, TT
Birrell, M
Harris, A
Mak, JCW
Scorer, C
Barnes, PJ
Adcock, IM
Giembycz, MA
Citation: Pa. Finney et al., Chronic systemic administration of salmeterol to rats promotes pulmonary beta(2)-adrenoceptor desensitization and down-regulation of G(s alpha), BR J PHARM, 132(6), 2001, pp. 1261-1270
Authors:
Finney, PA
Belvisi, MG
Donnelly, LE
Chuang, TT
Mak, JCW
Scorer, C
Barnes, PJ
Adcock, IM
Giembycz, MA
Citation: Pa. Finney et al., Albuterol-induced downregulation of Gs alpha accounts for pulmonary beta(2)-adrenoceptor desensitization in vivo, J CLIN INV, 106(1), 2000, pp. 125-135
Citation: Ma. Giembycz, Phosphodiesterase 4 inhibitors and the treatment of asthma - Where are we now and where do we go from here?, DRUGS, 59(2), 2000, pp. 193-212
Authors:
Meja, KK
Seldon, PM
Nasuhara, Y
Ito, K
Barnes, PJ
Lindsay, MA
Giembycz, MA
Citation: Kk. Meja et al., p38 MAP kinase and MKK-1 co-operate in the generation of GM-CSF from LPS-stimulated human monocytes by an NF-kappa B-independent mechanism, BR J PHARM, 131(6), 2000, pp. 1143-1153
Authors:
Koch, A
Nasuhara, Y
Barnes, PJ
Lindsay, MA
Giembycz, MA
Citation: A. Koch et al., Extracellular signal-regulated kinase 1/2 control Ca2+-independent force development in histamine-stimulated bovine tracheal smooth muscle, BR J PHARM, 131(5), 2000, pp. 981-989
Citation: Blj. Webb et al., Protein kinase C isoenzymes: a review of their structure, regulation and role in regulating airways smooth muscle tone and mitogenesis, BR J PHARM, 130(7), 2000, pp. 1433-1452
Citation: Ma. Giembycz, Phosphodiesterase inhibitors for respiratory diseases, HIGH THROUGHPUT SCREENING FOR NOVEL ANTI-INFLAMMATORIES, 2000, pp. 223-253
Authors:
Evans, DJ
Lindsay, MA
Webb, BLJ
Kankaanranta, H
Giembycz, MA
O'Connor, BJ
Barnes, PJ
Citation: Dj. Evans et al., Expression and activation of protein kinase C-zeta in eosinophils after allergen challenge, AM J P-LUNG, 21(2), 1999, pp. L233-L239
Authors:
Kankaanranta, H
De Souza, PM
Barnes, PJ
Salmon, M
Giembycz, MA
Lindsay, MA
Citation: H. Kankaanranta et al., SE 203580, an inhibitor of p38 mitogen-activated protein kinase, enhances constitutive apoptosis of cytokine-deprived human eosinophils, J PHARM EXP, 290(2), 1999, pp. 621-628
Authors:
Teixeira, MM
Lindsay, MA
Giembycz, MA
Hellewell, PG
Citation: Mm. Teixeira et al., Role of arachidonic acid in leukotriene B-4-induced guinea-pig eosinophil homotypic aggregation, EUR J PHARM, 384(2-3), 1999, pp. 183-190