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Results: 1-15 |
Results: 15
The PXR ligand-binding domain: how to be picky and promiscuous at the sametime
Authors: Gillam, EMJ
Citation: Emj. Gillam, The PXR ligand-binding domain: how to be picky and promiscuous at the sametime, TRENDS PHAR, 22(9), 2001, pp. 448-448
Metabolic activation of heterocyclic amines and other procarcinogens in Salmonella typhimurium umu tester strains expressing human cytochrome P4501A1, 1A2, 1B1, 2C9, 2D6, 2E1, and 3A4 and human NADPH-P450 reductase and bacterial O-acetyltransferase
Authors: Oda, Y Aryal, P Terashita, T Gillam, EMJ Guengerich, FP Shimada, T
Citation: Y. Oda et al., Metabolic activation of heterocyclic amines and other procarcinogens in Salmonella typhimurium umu tester strains expressing human cytochrome P4501A1, 1A2, 1B1, 2C9, 2D6, 2E1, and 3A4 and human NADPH-P450 reductase and bacterial O-acetyltransferase, MUT RES-GTE, 492(1-2), 2001, pp. 81-90
Metabolic activation of polycyclic aromatic hydrocarbons and other procarcinogens by cytochromes P450 1A1 and P4501B1 allelic variants and other human cytochromes P450 in Salmonella typhimurium NM2009
Authors: Shimada, T Oda, Y Gillam, EMJ Guengerich, FP Inoue, K
Citation: T. Shimada et al., Metabolic activation of polycyclic aromatic hydrocarbons and other procarcinogens by cytochromes P450 1A1 and P4501B1 allelic variants and other human cytochromes P450 in Salmonella typhimurium NM2009, DRUG META D, 29(9), 2001, pp. 1176-1182
Specificity of 17 beta-oestradiol and benzo[a] pyrene oxidation by polymorphic human cytochrome P4501B1 variants substituted at residues 48, 119 and 432
Authors: Shimada, T Watanabe, J Inoue, K Guengerich, FP Gillam, EMJ
Citation: T. Shimada et al., Specificity of 17 beta-oestradiol and benzo[a] pyrene oxidation by polymorphic human cytochrome P4501B1 variants substituted at residues 48, 119 and 432, XENOBIOTICA, 31(3), 2001, pp. 163-176
Roles of NADPH-P450 reductase in the O-deethylation of 7-ethoxycoumarin byrecombinant human cytochrome P4501B1 variants in Escherichia coli
Authors: Shimada, T Tsumura, F Gillam, EMJ Guengerich, FP Inoue, K
Citation: T. Shimada et al., Roles of NADPH-P450 reductase in the O-deethylation of 7-ethoxycoumarin byrecombinant human cytochrome P4501B1 variants in Escherichia coli, PROT EX PUR, 20(1), 2000, pp. 73-80
Association of CYP1B1 genetic polymorphism with incidence to breast and lung cancer
Authors: Watanabe, J Shimada, T Gillam, EMJ Ikuta, T Suemasu, K Higashi, Y Gotoh, O Kawajiri, K
Citation: J. Watanabe et al., Association of CYP1B1 genetic polymorphism with incidence to breast and lung cancer, PHARMACOGEN, 10(1), 2000, pp. 25-33
What makes P450s work? Searches for answers with known and new P450s
Authors: Guengerich, FP Parikh, A Yun, CH Kim, D Nakamura, K Notley, LM Gillam, EMJ
Citation: Fp. Guengerich et al., What makes P450s work? Searches for answers with known and new P450s, DRUG METAB, 32(3-4), 2000, pp. 267-281
Phenytoin metabolism by human cytochrome P450: Involvement of P450 3A and 2C forms in secondary metabolism and drug-protein adduct formation
Authors: Cuttle, L Munns, AJ Hogg, NA Scott, JR Hooper, WD Dickinson, RG Gillam, EMJ
Citation: L. Cuttle et al., Phenytoin metabolism by human cytochrome P450: Involvement of P450 3A and 2C forms in secondary metabolism and drug-protein adduct formation, DRUG META D, 28(8), 2000, pp. 945-950
Formation of a dihydroxy metabolite of phenytoin in human liver microsomes/cytosol: Roles of cytochromes P4502C9, 2C19, and 3A4
Authors: Komatsu, T Yamazaki, H Asahi, S Gillam, EMJ Guengerich, FP Nakajima, M Yokoi, T
Citation: T. Komatsu et al., Formation of a dihydroxy metabolite of phenytoin in human liver microsomes/cytosol: Roles of cytochromes P4502C9, 2C19, and 3A4, DRUG META D, 28(11), 2000, pp. 1361-1368
Oxidation of indole by cytochrome P450 enzymes
Authors: Gillam, EMJ Notley, LM Cai, HL De Voss, JJ Guengerich, FP
Citation: Emj. Gillam et al., Oxidation of indole by cytochrome P450 enzymes, BIOCHEM, 39(45), 2000, pp. 13817-13824
Metabolism of benzo[a]pyrene to trans-7,8-dihydroxy-7,8-dihydrobenzo[a]pyrene by recombinant human cytochrome P4501B1 and purified liver epoxide hydrolase
Authors: Shimada, T Gillam, EMJ Oda, Y Tsumura, F Sutter, TR Guengerich, FP Inoue, K
Citation: T. Shimada et al., Metabolism of benzo[a]pyrene to trans-7,8-dihydroxy-7,8-dihydrobenzo[a]pyrene by recombinant human cytochrome P4501B1 and purified liver epoxide hydrolase, CHEM RES T, 12(7), 1999, pp. 623-629
Catalytic properties of polymorphic human cytochrome P4501B1 variants
Authors: Shimada, T Watanabe, J Kawajiri, K Sutter, TR Guengerich, FP Gillam, EMJ Inoue, K
Citation: T. Shimada et al., Catalytic properties of polymorphic human cytochrome P4501B1 variants, CARCINOGENE, 20(8), 1999, pp. 1607-1613
Enhancement of cytochrome P-450 3A4 catalytic activities by cytochrome b(5) in bacterial membranes
Authors: Yamazaki, H Nakajima, M Nakamura, M Asahi, S Shimada, N Gillam, EMJ Guengerich, FP Shimada, T Yokoi, T
Citation: H. Yamazaki et al., Enhancement of cytochrome P-450 3A4 catalytic activities by cytochrome b(5) in bacterial membranes, DRUG META D, 27(9), 1999, pp. 999-1004
Formation of indigo by recombinant mammalian cytochrome P450
Authors: Gillam, EMJ Aguinaldo, AMA Notley, LM Kim, D Mundkowski, RG Volkov, AA Arnold, FH Soucek, P DeVoss, JJ Guengerich, FP
Citation: Emj. Gillam et al., Formation of indigo by recombinant mammalian cytochrome P450, BIOC BIOP R, 265(2), 1999, pp. 469-472
Twenty years of biochemistry of human P450s - Purification, expression, mechanism, and relevance to drugs
Authors: Guengerich, FP Hosea, NA Parikh, A Bell-Parikh, LC Johnson, WW Gillam, EMJ Shimada, T
Citation: Fp. Guengerich et al., Twenty years of biochemistry of human P450s - Purification, expression, mechanism, and relevance to drugs, DRUG META D, 26(12), 1998, pp. 1175-1178
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