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Aggretin, a heterodimeric C-type lectin from Calloselasma rhodostoma (Malayan pit viper), stimulates platelets by binding to alpha(2)beta(1) integrinand glycoprotein Ib, activating Syk and phospholipase C gamma 2, but does not involve the glycoprotein VI/Fc receptor gamma chain collagen receptor
Authors: Navdaev, A Clemetson, JM Polgar, J Kehrel, BE Glauner, M Magnenat, E Wells, TNC Clemetson, KJ
Citation: A. Navdaev et al., Aggretin, a heterodimeric C-type lectin from Calloselasma rhodostoma (Malayan pit viper), stimulates platelets by binding to alpha(2)beta(1) integrinand glycoprotein Ib, activating Syk and phospholipase C gamma 2, but does not involve the glycoprotein VI/Fc receptor gamma chain collagen receptor, J BIOL CHEM, 276(24), 2001, pp. 20882-20889
The vasodilator-stimulated phosphoprotein (VASP) is involved in cGMP- and cAMP-mediated inhibition of agonist-induced platelet aggregation, but is dispensable for smooth muscle function
Authors: Aszodi, A Pfeifer, A Ahmad, M Glauner, M Zhou, XH Ny, L Andersson, KE Kehrel, B Offermanns, S Fassler, R
Citation: A. Aszodi et al., The vasodilator-stimulated phosphoprotein (VASP) is involved in cGMP- and cAMP-mediated inhibition of agonist-induced platelet aggregation, but is dispensable for smooth muscle function, EMBO J, 18(1), 1999, pp. 37-48
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