Authors:
Andersson, TB
Sjoberg, H
Hoffmann, KJ
Boobis, AR
Watts, P
Edwards, RJ
Lake, BG
Price, RJ
Renwick, AB
Gomez-Lechon, MJ
Castell, JV
Ingelman-Sundberg, M
Hidestrand, M
Goldfarb, PS
Lewis, DFV
Corcos, L
Guillouzo, A
Taavitsainen, P
Pelkonen, O
Citation: Tb. Andersson et al., An assessment of human liver-derived in vitro systems to predict the in vivo metabolism and clearance of almokalant, DRUG META D, 29(5), 2001, pp. 712-720
Authors:
Pelkonen, O
Myllynen, P
Taavitsainen, P
Boobis, AR
Watts, P
Lake, BG
Price, RJ
Renwick, AB
Gomez-Lechon, MJ
Castell, JV
Ingelman-Sundberg, M
Hidestrand, M
Guillouzo, A
Corcos, L
Goldfarb, PS
Lewis, DFV
Citation: O. Pelkonen et al., Carbamazepine: a 'blind' assessment of CYP-associated metabolism and interactions in human liver-derived in vitro systems, XENOBIOTICA, 31(6), 2001, pp. 321-343
Authors:
Lewis, DFV
Bird, MG
Dickins, M
Lake, BG
Eddershaw, PJ
Tarbit, MH
Goldfarb, PS
Citation: Dfv. Lewis et al., Molecular modelling of human CYP2E1 by homology with the CYP102 haemoprotein domain: investigation of the interactions of substrates and inhibitors within the putative active site of the human CYP2E1 isoform, XENOBIOTICA, 30(1), 2000, pp. 1-25
Authors:
Lewis, DFV
Lake, BG
George, SG
Dickins, M
Eddershaw, PJ
Tarbit, MH
Beresford, AP
Goldfarb, PS
Guengerich, FP
Citation: Dfv. Lewis et al., Molecular modelling of CYP1 family enzymes CYP1A1, CYP1A2, CYP1A6 and CYP1B1 based on sequence homology with CYP102, TOXICOLOGY, 139(1-2), 1999, pp. 53-79
Authors:
Lewis, DFV
Dickens, M
Lake, BG
Eddershaw, PJ
Tarbit, MH
Goldfarb, PS
Citation: Dfv. Lewis et al., Molecular modelling of the human cytochrome P450 isoform CYP2A6 and investigations of CYP2A substrate selectivity, TOXICOLOGY, 133(1), 1999, pp. 1-33
Authors:
Lewis, DFV
Lake, BG
Dickins, M
Eddershaw, PJ
Tarbit, MH
Goldfarb, PS
Citation: Dfv. Lewis et al., Molecular modelling of CYP2B6, the human CYP2B isoform, by homology with the substrate-bound CYP102 crystal structure: evaluation of CYP2B6 substratecharacteristics, the cytochrome b(5) binding site and comparisons with CYP2B1 and CYP2B4, XENOBIOTICA, 29(4), 1999, pp. 361-393
Authors:
Ogg, MS
Williams, JM
Tarbit, M
Goldfarb, PS
Gray, TJB
Gibson, GG
Citation: Ms. Ogg et al., A reporter gene assay to assess the molecular mechanisms of xenobiotic-dependent induction of the human CYP3A4 gene in vitro, XENOBIOTICA, 29(3), 1999, pp. 269-279
Citation: Dfv. Lewis et al., Structural determinants of cytochrome P450 substrate specificity, binding affinity and catalytic rate (vol 115, pg 186, 1998), CHEM-BIO IN, 117(2), 1999, pp. 187-187