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Results: 1-21 |
Results: 21
An episomally maintained MDR1 gene for gene therapy
Authors: Lee, CGL Vieira, WD Pastan, I Gottesman, MM
Citation: Cgl. Lee et al., An episomally maintained MDR1 gene for gene therapy, HUM GENE TH, 12(8), 2001, pp. 945-953
Targeting the human mdr1 gene by I-125-labeled triplex-forming oligonucleotides
Authors: Sedelnikova, OA Panyutin, IG Luu, AN Reed, MW Licht, T Gottesman, MM Neumann, RD
Citation: Oa. Sedelnikova et al., Targeting the human mdr1 gene by I-125-labeled triplex-forming oligonucleotides, ANTISENSE N, 10(6), 2000, pp. 443-452
Chemoprotection of hematopoietic cells by a mutant p-glycoprotein resistant to a potent chemosensitizer of multidrug-resistant cancers (vol 11, pg 563, 2000)
Authors: Hafkemeyer, P Licht, T Pastan, I Gottesman, MM
Citation: P. Hafkemeyer et al., Chemoprotection of hematopoietic cells by a mutant p-glycoprotein resistant to a potent chemosensitizer of multidrug-resistant cancers (vol 11, pg 563, 2000), HUM GENE TH, 11(7), 2000, pp. 1112-1112
Chemoprotection of hematopoietic cells by a mutant P-glycoprotein resistant to a potent chemosensitizer of multidrug-resistant cancers
Authors: Hafkemeyer, P Licht, T Pastan, I Gottesman, MM
Citation: P. Hafkemeyer et al., Chemoprotection of hematopoietic cells by a mutant P-glycoprotein resistant to a potent chemosensitizer of multidrug-resistant cancers, HUM GENE TH, 11(4), 2000, pp. 555-565
Drug selection of MDR1-transduced hematopoietic cells ex vivo increases transgene expression and chemoresistance in reconstituted bone marrow in mice
Authors: Licht, T Goldenberg, SK Vieira, WD Gottesman, MM Pastan, I
Citation: T. Licht et al., Drug selection of MDR1-transduced hematopoietic cells ex vivo increases transgene expression and chemoresistance in reconstituted bone marrow in mice, GENE THER, 7(4), 2000, pp. 348-358
Effect of ABC transporters on HIV-1 infection: inhibition of virus production by the MDR1 transporter
Authors: Lee, CGL Ramachandra, M Jeang, KT Martin, MA Pastan, I Gottesman, MM
Citation: Cgl. Lee et al., Effect of ABC transporters on HIV-1 infection: inhibition of virus production by the MDR1 transporter, FASEB J, 14(3), 2000, pp. 516-522
Math and science education: Training the teachers
Authors: Gottesman, MM Shmookler, SR
Citation: Mm. Gottesman et Sr. Shmookler, Math and science education: Training the teachers, SCIENCE, 290(5490), 2000, pp. 273-273
Organizer's introduction to the Symposium "Medical Research Ethics at the Millennium: What Have We Learned?"
Authors: Nussenblatt, RB Gottesman, MM
Citation: Rb. Nussenblatt et Mm. Gottesman, Organizer's introduction to the Symposium "Medical Research Ethics at the Millennium: What Have We Learned?", PERSP BIOL, 43(3), 2000, pp. 305-307
Decreased accumulation of [C-14]carboplatin in human cisplatin-resistant cells results from reduced energy-dependent uptake
Authors: Shen, DW Goldenberg, S Pastan, I Gottesman, MM
Citation: Dw. Shen et al., Decreased accumulation of [C-14]carboplatin in human cisplatin-resistant cells results from reduced energy-dependent uptake, J CELL PHYS, 183(1), 2000, pp. 108-116
Analysis of the properties of the N-terminal nucleotide-binding domain of human P-glycoprotein
Authors: Booth, CL Pulaski, L Gottesman, MM Pastan, L
Citation: Cl. Booth et al., Analysis of the properties of the N-terminal nucleotide-binding domain of human P-glycoprotein, BIOCHEM, 39(18), 2000, pp. 5518-5526
Selectable markers for gene therapy
Authors: Gottesman, MM Licht, T Zhou, Y Lee, C Shoshani-Kupitz, T Hafkemeyer, P Hrycyna, CA Pastan, I
Citation: Mm. Gottesman et al., Selectable markers for gene therapy, GENE THERAPY, 2000, pp. 333-352
Paclitaxel chemotherapy after autologous stem-cell transplantation and engraftment of hematopoietic cells transduced with a retrovirus containing themultidrug resistance complementary DNA (MDR1) in metastatic breast cancer patients
Authors: Cowan, KH Moscow, JA Huang, H Zujewski, JA O'Shaughnessy, J Sorrentino, B Hines, K Carter, C Schneider, E Cusack, G Noone, M Dunbar, C Steinberg, S Wilson, W Goldspiel, B Read, EJ Leitman, SF McDonagh, K Chow, C Abati, A Chiang, Y Chang, YN Gottesman, MM Pastan, I Nienhuis, A
Citation: Kh. Cowan et al., Paclitaxel chemotherapy after autologous stem-cell transplantation and engraftment of hematopoietic cells transduced with a retrovirus containing themultidrug resistance complementary DNA (MDR1) in metastatic breast cancer patients, CLIN CANC R, 5(7), 1999, pp. 1619-1628
Therapeutic strategies involving the multidrug resistance phenotype: The MDRI gene as target, chemoprotectant, and selectable marker in gene therapy
Authors: Aran, JM Pastan, I Gottesman, MM
Citation: Jm. Aran et al., Therapeutic strategies involving the multidrug resistance phenotype: The MDRI gene as target, chemoprotectant, and selectable marker in gene therapy, ADV PHARM, 46, 1999, pp. 1-42
Apoptosis induced by Pseudomonas exotoxin: A sensitive and rapid marker for gene delivery in vivo
Authors: Hafkemeyer, P Brinkmann, U Gottesman, MM Pastan, I
Citation: P. Hafkemeyer et al., Apoptosis induced by Pseudomonas exotoxin: A sensitive and rapid marker for gene delivery in vivo, HUM GENE TH, 10(6), 1999, pp. 923-934
Retroviral transfer of human MDR1 gene to hematopoietic cells: Effects of drug selection and of transcript splicing on expression of encoded P-glycoprotein
Authors: Licht, T Aran, JM Goldenberg, SK Vieira, WD Gottesman, MM Pastan, I
Citation: T. Licht et al., Retroviral transfer of human MDR1 gene to hematopoietic cells: Effects of drug selection and of transcript splicing on expression of encoded P-glycoprotein, HUM GENE TH, 10(13), 1999, pp. 2173-2185
Biochemical, cellular, and pharmacological aspects of the multidrug transporter
Authors: Ambudkar, SV Dey, S Hrycyna, CA Ramachandra, M Pastan, I Gottesman, MM
Citation: Sv. Ambudkar et al., Biochemical, cellular, and pharmacological aspects of the multidrug transporter, ANN R PHARM, 39, 1999, pp. 361-398
Studies of human MDR1-MDR2 chimeras demonstrate the functional exchangeability of a major transmembrane segment of the multidrug transporter and phosphatidylcholine flippase
Authors: Zhou, Y Gottesman, MM Pastan, I
Citation: Y. Zhou et al., Studies of human MDR1-MDR2 chimeras demonstrate the functional exchangeability of a major transmembrane segment of the multidrug transporter and phosphatidylcholine flippase, MOL CELL B, 19(2), 1999, pp. 1450-1459
Domain exchangeability between the multidrug transporter (MDR1) and phosphatidylcholine flippase (MDR2)
Authors: Zhou, Y Gottesman, MM Pastan, I
Citation: Y. Zhou et al., Domain exchangeability between the multidrug transporter (MDR1) and phosphatidylcholine flippase (MDR2), MOLEC PHARM, 56(5), 1999, pp. 997-1004
Engraftment of MDR1 and NeoR gene-transduced hematopoietic cells after breast cancer chemotherapy
Authors: Moscow, JA Huang, H Carter, C Hines, K Zujewski, J Cusack, G Chow, C Venzon, D Sorrentino, B Chiang, YW Goldspiel, B Leitman, S Read, EJ Abati, A Gottesman, MM Pastan, I Sellers, S Dunbar, C Cowan, KH
Citation: Ja. Moscow et al., Engraftment of MDR1 and NeoR gene-transduced hematopoietic cells after breast cancer chemotherapy, BLOOD, 94(1), 1999, pp. 52-61
A single amino acid residue contributes to distinct mechanisms of inhibition of the human multidrug transporter by stereoisomers of the dopamine receptor antagonist flupentixol
Authors: Dey, S Hafkemeyer, P Pastan, I Gottesman, MM
Citation: S. Dey et al., A single amino acid residue contributes to distinct mechanisms of inhibition of the human multidrug transporter by stereoisomers of the dopamine receptor antagonist flupentixol, BIOCHEM, 38(20), 1999, pp. 6630-6639
The extracellular loop between TM5 and TM6 of P-glycoprotein is required for reactivity with monoclonal antibody UIC2
Authors: Zhou, Y Gottesman, MM Pastan, I
Citation: Y. Zhou et al., The extracellular loop between TM5 and TM6 of P-glycoprotein is required for reactivity with monoclonal antibody UIC2, ARCH BIOCH, 367(1), 1999, pp. 74-80
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