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Results: 1-17 |
Results: 17
2-(3,5-dimethylphenyl)tryptamine derivatives that bind to the GnRH receptor
Authors: Lin, P Marino, D Lo, JL Yang, YT Cheng, K Smith, RG Fisher, MH Wyvratt, MJ Goulet, MT
Citation: P. Lin et al., 2-(3,5-dimethylphenyl)tryptamine derivatives that bind to the GnRH receptor, BIOORG MED, 11(8), 2001, pp. 1073-1076
Heterocyclic derivatives of 2-(3,5-dimethylphenyl)tryptamine as GnRH receptor antagonists
Authors: Lin, P Parikh, M Lo, JL Yang, YT Cheng, K Smith, RG Fisher, MH Wyvratt, MJ Goulet, MT
Citation: P. Lin et al., Heterocyclic derivatives of 2-(3,5-dimethylphenyl)tryptamine as GnRH receptor antagonists, BIOORG MED, 11(8), 2001, pp. 1077-1080
Initial structure-activity relationship of a novel class of nonpeptidyl GnRH receptor antagonists: 2-arylindoles
Authors: Chu, L Hutchins, JE Weber, AE Lo, JL Yang, YT Cheng, K Smith, RG Fisher, MH Wyvratt, MJ Goulet, MT
Citation: L. Chu et al., Initial structure-activity relationship of a novel class of nonpeptidyl GnRH receptor antagonists: 2-arylindoles, BIOORG MED, 11(4), 2001, pp. 509-513
SAR studies of novel 5-substituted 2-arylindoles as nonpeptidyl GnRH receptor antagonists
Authors: Chu, L Lo, JL Yang, YT Cheng, K Smith, RG Fisher, MH Wyvratt, MJ Goulet, MT
Citation: L. Chu et al., SAR studies of novel 5-substituted 2-arylindoles as nonpeptidyl GnRH receptor antagonists, BIOORG MED, 11(4), 2001, pp. 515-517
Orally bioavailable, indole-based nonpeptide GnRH receptor antagonists with high potency and functional activity
Authors: Ashton, WT Sisco, RM Kieczykowski, GR Yang, YT Yudkovitz, JB Cui, JS Mount, GR Ren, RN Wu, TJ Shen, XL Lyons, KA Mao, AH Carlin, JR Karanam, BV Vincent, SH Cheng, K Goulet, MT
Citation: Wt. Ashton et al., Orally bioavailable, indole-based nonpeptide GnRH receptor antagonists with high potency and functional activity, BIOORG MED, 11(19), 2001, pp. 2597-2602
Substituted indole-5-carboxamides and -acetamides as potent nonpeptide GnRH receptor antagonists
Authors: Ashton, WT Sisco, RM Yang, YT Lo, JL Yudkovitz, JB Cheng, K Goulet, MT
Citation: Wt. Ashton et al., Substituted indole-5-carboxamides and -acetamides as potent nonpeptide GnRH receptor antagonists, BIOORG MED, 11(13), 2001, pp. 1723-1726
Potent nonpeptide GnRH receptor antagonists derived from substituted indole-5-carboxamides and -acetamides bearing a pyridine side-chain terminus
Authors: Ashton, WT Sisco, RM Yang, YT Lo, JL Yudkovitz, JB Gibbons, PH Mount, GR Ren, RN Butler, BS Cheng, K Goulet, MT
Citation: Wt. Ashton et al., Potent nonpeptide GnRH receptor antagonists derived from substituted indole-5-carboxamides and -acetamides bearing a pyridine side-chain terminus, BIOORG MED, 11(13), 2001, pp. 1727-1731
A convergent synthesis of (S)-beta-methyl-2-aryltryptamine based gonadotropin releasing hormone antagonists
Authors: Walsh, TF Toupence, RB Ujjainwalla, F Young, JR Goulet, MT
Citation: Tf. Walsh et al., A convergent synthesis of (S)-beta-methyl-2-aryltryptamine based gonadotropin releasing hormone antagonists, TETRAHEDRON, 57(24), 2001, pp. 5233-5241
A potent, nonpeptidyl 1H-quinolone antagonist for the gonadotropin-releasing hormone receptor
Authors: DeVita, RJ Walsh, TF Young, JR Jiang, JL Ujjainwalla, F Toupence, RB Parikh, M Huang, SX Fair, JA Goulet, MT Wyvratt, MJ Lo, JL Ren, N Yudkovitz, JB Yang, YT Cheng, K Cui, JS Mount, G Rohrer, SP Schaeffer, JM Rhodes, L Drisko, JE McGowan, E MacIntyre, DE Vincent, S Carlin, JR Cameron, J Smith, RG
Citation: Rj. Devita et al., A potent, nonpeptidyl 1H-quinolone antagonist for the gonadotropin-releasing hormone receptor, J MED CHEM, 44(6), 2001, pp. 917-922
Potent antagonists of gonadotropin releasing hormone receptors derived from quinolone-6-carboxamides
Authors: Walsh, TF Toupence, RB Young, JR Huang, SX Ujjainwalla, F DeVita, RJ Goulet, MT Wyvratt, MJ Fisher, MH Lo, JL Ren, N Yudkovitz, JB Yang, YT Cheng, K Smith, RG
Citation: Tf. Walsh et al., Potent antagonists of gonadotropin releasing hormone receptors derived from quinolone-6-carboxamides, BIOORG MED, 10(5), 2000, pp. 443-447
Quinolones as gonadotropin releasing hormone (GnRH) antagonists: Simultaneous optimization of the C(3)-aryl and C(6)-substituents
Authors: Young, JR Huang, SX Chen, I Walsh, TF DeVita, RJ Wyvratt, MJ Goulet, MT Ren, N Lo, J Yang, YT Yudkovitz, JB Cheng, K Smith, RG
Citation: Jr. Young et al., Quinolones as gonadotropin releasing hormone (GnRH) antagonists: Simultaneous optimization of the C(3)-aryl and C(6)-substituents, BIOORG MED, 10(15), 2000, pp. 1723-1727
Identification of Phe(313) of the gonadotropin-releasing hormone (GnRH) receptor as a site critical for the binding of nonpeptide GnRH antagonists
Authors: Cui, JS Smith, RG Mount, GR Lo, JL Yu, JH Walsh, TF Singh, SB DeVita, RJ Goulet, MT Schaeffer, JM Cheng, K
Citation: Js. Cui et al., Identification of Phe(313) of the gonadotropin-releasing hormone (GnRH) receptor as a site critical for the binding of nonpeptide GnRH antagonists, MOL ENDOCR, 14(5), 2000, pp. 671-681
Identification and initial structure-activity relationships of a novel non-peptide quinolone GnRH receptor antagonist
Authors: DeVita, RJ Hollings, DD Goulet, MT Wyvratt, MJ Fisher, MH Lo, JL Yang, YT Cheng, K Smith, RG
Citation: Rj. Devita et al., Identification and initial structure-activity relationships of a novel non-peptide quinolone GnRH receptor antagonist, BIOORG MED, 9(17), 1999, pp. 2615-2620
Investigation of the 4-O-alkylamine substituent of non-peptide quinolone GnRH receptor antagonists
Authors: DeVita, RJ Goulet, MT Wyvratt, MJ Fisher, MH Lo, JL Yang, YT Cheng, K Smith, RG
Citation: Rj. Devita et al., Investigation of the 4-O-alkylamine substituent of non-peptide quinolone GnRH receptor antagonists, BIOORG MED, 9(17), 1999, pp. 2621-2624
C32-O-Phenalkyl ether derivatives of the immunosuppressant ascomycin: a tether length study
Authors: Goulet, MT Sinclair, PT Wong, F Staruch, MJ Dumont, FJ Cryan, JG Wiederrecht, GJ Wyvratt, MJ Parsons, WH
Citation: Mt. Goulet et al., C32-O-Phenalkyl ether derivatives of the immunosuppressant ascomycin: a tether length study, BIOORG MED, 9(14), 1999, pp. 2085-2088
Potent immunosuppressive C32-O-arylethyl ether derivatives of ascomycin with reduced toxicity.
Authors: Armstrong, HM Wong, F Holmes, MA Sinclair, PJ Goulet, MT Dumont, FJ Staruch, M Koprak, S Peterson, LB Rosa, R Wilusz, MB Wiederrecht, GJ Cryan, JG Wyvratt, MJ Parsons, WH
Citation: Hm. Armstrong et al., Potent immunosuppressive C32-O-arylethyl ether derivatives of ascomycin with reduced toxicity., BIOORG MED, 9(14), 1999, pp. 2089-2094
Asymmetric synthesis of chiral, nonracemic trifluoromethyl-substituted piperidines and decahydroquinolines
Authors: Jiang, JL DeVita, RJ Doss, GA Goulet, MT Wyvratt, MJ
Citation: Jl. Jiang et al., Asymmetric synthesis of chiral, nonracemic trifluoromethyl-substituted piperidines and decahydroquinolines, J AM CHEM S, 121(3), 1999, pp. 593-594
Risultati: 1-17 |