Authors:
Ciraulo, DA
Knapp, CM
LoCastro, J
Greenblatt, DJ
Shader, RI
Citation: Da. Ciraulo et al., A benzodiazepine mood effect scale: Reliability and validity determined for alcohol-dependent subjects and adults with a parental history of alcoholism, AM J DRUG A, 27(2), 2001, pp. 339-347
Authors:
Venkatakrishnan, K
von Moltke, LL
Greenblatt, DJ
Citation: K. Venkatakrishnan et al., Human drug metabolism and the cytochromes P450: Application and relevance of in vitro models, J CLIN PHAR, 41(11), 2001, pp. 1149-1179
Authors:
Venkatakrishnan, K
Schmider, J
Harmatz, JS
Ehrenberg, BL
von Moltke, LL
Graf, JA
Mertzanis, P
Corbett, KE
Rodriguez, MC
Shader, RI
Greenblatt, DJ
Citation: K. Venkatakrishnan et al., Relative contribution of CYP3A to amitriptyline clearance in humans: In vitro and in vivo studies, J CLIN PHAR, 41(10), 2001, pp. 1043-1054
Authors:
von Moltke, LL
Greenblatt, DJ
Granda, BW
Giancarlo, GM
Duan, SX
Daily, JP
Harmatz, JS
Shader, RI
Citation: Ll. Von Moltke et al., Inhibition of human cytochrome P450 isoforms by nonnucleoside reverse transcriptase inhibitors, J CLIN PHAR, 41(1), 2001, pp. 85-91
Authors:
Von Moltke, LL
Greenblatt, DJ
Giancarlo, GM
Granda, BW
Harmatz, JS
Shader, RI
Citation: Ll. Von Moltke et al., Escitalopram (S-citalopram) and its metabolites in vitro: cytochromes mediating biotransformation, inhibitory effects, and comparison to R-citalopram, DRUG META D, 29(8), 2001, pp. 1102-1109
Authors:
Hesse, LM
von Moltke, LL
Shader, RI
Greenblatt, DJ
Citation: Lm. Hesse et al., Ritonavir, efavirenz, and nelfinavir inhibit CYP2B6 activity in vitro: Potential drug interactions with bupropion, DRUG META D, 29(2), 2001, pp. 100-102
Authors:
Hesse, LM
Venkatakrishnan, K
Von Moltke, LL
Shader, RI
Greenblatt, DJ
Citation: Lm. Hesse et al., CYP3A4 is the major CYP isoform mediating the in vitro hydroxylation and demethylation of flunitrazepam, DRUG META D, 29(2), 2001, pp. 133-140
Authors:
Giancarlo, GM
Venkatakrishnan, K
Granda, BW
von Moltke, LL
Greenblatt, DJ
Citation: Gm. Giancarlo et al., Relative contributions of CYP2C9 and 2C19 to phenytoin 4-hydroxylation in vitro: inhibition by sulfaphenazole, omeprazole, and ticlopidine, EUR J CL PH, 57(1), 2001, pp. 31-36
Authors:
Court, MH
Duan, SX
Von Moltke, LL
Greenblatt, DJ
Patten, CJ
Miners, JO
Mackenzie, PI
Citation: Mh. Court et al., Interindividual variability in acetaminophen glucuronidation by human liver microsomes: Identification of relevant acetaminophen UDP-glucuronosyltransferase isoforms, J PHARM EXP, 299(3), 2001, pp. 998-1006
Authors:
Venkatakrishnan, K
Von Moltke, LL
Greenblatt, DJ
Citation: K. Venkatakrishnan et al., Application of the relative activity factor approach in scaling from heterologously expressed cytochromes P450 to human liver microsomes: Studies on amitriptyline as a model substrate, J PHARM EXP, 297(1), 2001, pp. 326-337
Authors:
Perloff, MD
von Moltke, LL
Marchand, JE
Greenblatt, DJ
Citation: Md. Perloff et al., Ritonavir induces P-glycoprotein expression, multidrug resistance-associated protein (MRP1) expression, and drug transporter-mediated activity in a human intestinal cell line, J PHARM SCI, 90(11), 2001, pp. 1829-1837
Authors:
Soriano, SG
Sullivan, LJ
Venkatakrishnan, K
Greenblatt, DJ
Martyn, JAJ
Citation: Sg. Soriano et al., Pharmacokinetics and pharmacodynamics of vecuronium in children receiving phenytoin or carbamazepine for chronic anticonvulsant therapy, BR J ANAEST, 86(2), 2001, pp. 223-229
Authors:
Court, MH
Duan, SX
Hesse, LM
Venkatakrishnan, K
Greenblatt, DJ
Citation: Mh. Court et al., Cytochrome P-4502B6 is responsible for interindividual variability of propofol hydroxylation by human liver microsomes, ANESTHESIOL, 94(1), 2001, pp. 110-119
Authors:
Cotreau, MM
von Moltke, LL
Beinfeld, MC
Greenblatt, DJ
Citation: Mm. Cotreau et al., Methodologies to study the induction of rat hepatic and intestinal cytochrome P450 3A at the mRNA, protein, and catalytic activity level, J PHARM TOX, 43(1), 2000, pp. 41-54
Citation: Mh. Court et Dj. Greenblatt, Molecular genetic basis for deficient acetaminophen glucuronidation by cats: UGT1A6 is a pseudogene, and evidence for reduced diversity of expressed hepatic UGT1A isoforms, PHARMACOGEN, 10(4), 2000, pp. 355-369
Authors:
Venkatakrishnan, K
von Moltke, LL
Greenblatt, DJ
Citation: K. Venkatakrishnan et al., Effects of the antifungal agents on oxidative drug metabolism - Clinical relevance, CLIN PHARMA, 38(2), 2000, pp. 111-180
Authors:
Busto, UE
Kaplan, HL
Wright, CE
Gomez-Mancilla, B
Zawertailo, L
Greenblatt, DJ
Sellers, EM
Citation: Ue. Busto et al., A comparative pharmacokinetic and dynamic evaluation of alprazolam sustained-release, bromazepam, and lorazepam, J CL PSYCH, 20(6), 2000, pp. 628-635