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Results: 1-25/36
Authors:
Langouet, S
Welti, DH
Kerriguy, N
Fay, LB
Huynh-Ba, T
Markovic, J
Guengerich, FP
Guillouzo, A
Turesky, RJ
Citation: S. Langouet et al., Metabolism of 2-amino-3,8-dimethylimidazo [4,5-f]quinoxaline in human hepatocytes: 2-Amino-3-methylimidazo[4,5-f]quinoxaline-8-carboxylic acid is a major detoxication pathway catalyzed by cytochrome P450 1A2 (vol 14, pg 211,2001), CHEM RES T, 14(5), 2001, pp. 609-609
Authors:
Langouet, S
Welti, DH
Kerriguy, N
Fay, LB
Huynh-Ba, T
Markovic, J
Guengerich, FP
Guillouzo, A
Turesky, RJ
Citation: S. Langouet et al., Metabolism of 2-amino-3,8-dimethylimidazo[4,5-f] quinoxaline in human hepatocytes: 2-Amino-3-methylimidazo [4,5-f]quinoxaline-8-carboxylic acid is a major detoxication pathway catalyzed by cytochrome P450 1A2, CHEM RES T, 14(2), 2001, pp. 211-221
Authors:
Payen, L
Courtois, A
Langouet, S
Guillouzo, A
Fardel, O
Citation: L. Payen et al., Unaltered expression of multidrug resistance transporters in polycyclic aromatic hydrocarbon-resistant rat liver cells, TOXICOLOGY, 156(2-3), 2001, pp. 109-117
Authors:
Le Ferrec, E
Ilyin, G
Maheo, K
Bardiau, C
Courtois, A
Guillouzo, A
Morel, F
Citation: E. Le Ferrec et al., Differential effects of oltipraz on CYP1A and CYP2B in rat lung, CARCINOGENE, 22(1), 2001, pp. 49-55
Authors:
Andersson, TB
Sjoberg, H
Hoffmann, KJ
Boobis, AR
Watts, P
Edwards, RJ
Lake, BG
Price, RJ
Renwick, AB
Gomez-Lechon, MJ
Castell, JV
Ingelman-Sundberg, M
Hidestrand, M
Goldfarb, PS
Lewis, DFV
Corcos, L
Guillouzo, A
Taavitsainen, P
Pelkonen, O
Citation: Tb. Andersson et al., An assessment of human liver-derived in vitro systems to predict the in vivo metabolism and clearance of almokalant, DRUG META D, 29(5), 2001, pp. 712-720
Authors:
Pelkonen, O
Myllynen, P
Taavitsainen, P
Boobis, AR
Watts, P
Lake, BG
Price, RJ
Renwick, AB
Gomez-Lechon, MJ
Castell, JV
Ingelman-Sundberg, M
Hidestrand, M
Guillouzo, A
Corcos, L
Goldfarb, PS
Lewis, DFV
Citation: O. Pelkonen et al., Carbamazepine: a 'blind' assessment of CYP-associated metabolism and interactions in human liver-derived in vitro systems, XENOBIOTICA, 31(6), 2001, pp. 321-343
Authors:
Vernhet, L
Seite, MP
Allain, N
Guillouzo, A
Fardel, O
Citation: L. Vernhet et al., Arsenic induces expression of the multidrug resistance-associated protein 2 (MRP2) gene in primary rat and human hepatocytes, J PHARM EXP, 298(1), 2001, pp. 234-239
Authors:
Desmots, F
Rauch, C
Ylyin, GP
Guillouzo, A
Morel, F
Citation: F. Desmots et al., Structure and organization of a human glutathione transferase A4 pseudogene, CHEM-BIO IN, 133(1-3), 2001, pp. 315-319
Authors:
Payen, L
Delugin, L
Courtois, A
Trinquart, Y
Guillouzo, A
Fardel, O
Citation: L. Payen et al., The sulphonylurea glibenclamide inhibits multidrug resistance protein (MRP1) activity in human lung cancer cells, BR J PHARM, 132(3), 2001, pp. 778-784
Authors:
Vernhet, L
Allain, N
Payen, L
Anger, JP
Guillouzo, A
Fardel, O
Citation: L. Vernhet et al., Resistance of human multidrug resistance-associated protein 1-overexpressing lung tumor cells to the anticancer drug arsenic trioxide, BIOCH PHARM, 61(11), 2001, pp. 1387-1391
Authors:
Payen, L
Courtois, A
Loewert, M
Guillouzo, A
Fardel, O
Citation: L. Payen et al., Reactive oxygen species-related induction of multidrug resistance-associated protein 2 expression in primary hepatocytes exposed to sulforaphane, BIOC BIOP R, 282(1), 2001, pp. 257-263
Authors:
Langouet, S
Furge, LL
Kerriguy, N
Nakamura, K
Guillouzo, A
Guengerich, FP
Citation: S. Langouet et al., Inhibition of human cytochrome P450 enzymes by 1,2-dithiole-3-thione, oltipraz and its derivatives, and sulforaphane, CHEM RES T, 13(4), 2000, pp. 245-252
Authors:
Joannard, F
Galisteo, M
Corcos, L
Guillouzo, A
Lagadic-Gossmann, D
Citation: F. Joannard et al., Regulation of phenobarbital-induction of CYP2B and CYP3A genes in rat cultured hepatocytes: involvement of several serine/threonine protein kinases and phosphatases, CELL BIOL T, 16(5), 2000, pp. 325-337
Authors:
Lagadic-Gossmann, D
Lerche, C
Rissel, M
Joannard, F
Galisteo, M
Guillouzo, A
Corcos, L
Citation: D. Lagadic-gossmann et al., The induction of the human hepatic CYP2E1 gene by interleukin 4 is transcriptional and regulated by protein kinase C, CELL BIOL T, 16(4), 2000, pp. 221-233
Authors:
Rialland, L
Guyomard, C
Scotte, M
Chesne, C
Guillouzo, A
Citation: L. Rialland et al., Viability and drug metabolism capacity of alginate-entrapped hepatocytes after cryopreservation, CELL BIOL T, 16(2), 2000, pp. 105-116
Authors:
Pons, F
Haag, M
Corcos, L
Bonnet, P
Guillouzo, A
Lugnier, A
Frossard, N
Citation: F. Pons et al., Inhalation of toluene diisocyanate affects cytochrome P4502B1 expression in rat lung, ARCH TOXIC, 74(7), 2000, pp. 397-403
Authors:
Lecureur, V
Courtois, A
Payen, L
Verhnet, L
Guillouzo, A
Fardel, O
Citation: V. Lecureur et al., Expression and regulation of hepatic drug and bile acid transporters, TOXICOLOGY, 153(1-3), 2000, pp. 203-219
Authors:
Galisteo, M
Rissel, M
Sergent, O
Chevanne, M
Cillard, J
Guillouzo, A
Lagadic-Gossmann, D
Citation: M. Galisteo et al., Hepatotoxicity of tacrine: Occurrence of membrane fluidity alterations without involvement of lipid peroxidation, J PHARM EXP, 294(1), 2000, pp. 160-167
Authors:
Marc, N
Galisteo, M
Lagadic-Gossmann, D
Fautrel, A
Joannard, F
Guillouzo, A
Corcos, L
Citation: N. Marc et al., Regulation of phenobarbital induction of the cytochrome P450 2b9/10 genes in primary mouse hepatocyte culture - Involvement of calcium- and cAMP-dependent pathways, EUR J BIOCH, 267(4), 2000, pp. 963-970
Authors:
Payen, L
Courtois, A
Campion, JP
Guillouzo, A
Fardel, O
Citation: L. Payen et al., Characterization and inhibition by a wide range of xenobiotics of organic anion excretion by primary human hepatocytes, BIOCH PHARM, 60(12), 2000, pp. 1967-1975
Authors:
Marc, N
Fautrel, A
Damon, M
Guillouzo, A
Corcos, L
Citation: N. Marc et al., Phenobarbital induction of aldehyde dehydrogenase type 2 mRNA in mouse liver: A candidate region on chromosome 7 for a putative regulatory gene, BIOCHEM GEN, 38(9-10), 2000, pp. 297-307
Authors:
Le Marrec-Croq, F
Glaise, D
Guguen-Guillouzo, C
Chesne, C
Guillouzo, A
Boulo, V
Dorange, G
Citation: F. Le Marrec-croq et al., Primary cultures of heart cells from the scallop Pecten maximus (Mollusca-Bivalvia), IN VITRO-AN, 35(5), 1999, pp. 289-295
Authors:
Courtois, A
Payen, L
Vernhet, L
de Vries, EGE
Guillouzo, A
Fardel, O
Citation: A. Courtois et al., Inhibition of multidrug resistance-associated protein (MRP) activity by rifampicin in human multidrug-resistant lung tumor cells, CANCER LETT, 139(1), 1999, pp. 97-104
Authors:
Courtois, A
Payen, L
Vernhet, L
Morel, F
Guillouzo, A
Fardel, O
Citation: A. Courtois et al., Differential regulation of canalicular multispecific organic anion transporter (cMOAT) expression by the chemopreventive agent oltipraz in primary rat hepatocytes and in rat liver, CARCINOGENE, 20(12), 1999, pp. 2327-2330
Authors:
Desille, M
Corcos, L
L'Helgoualc'h, A
Fremond, B
Campion, JP
Guillouzo, A
Clement, B
Citation: M. Desille et al., Detoxifying activity in pig livers and hepatocytes intended for xenotherapy, TRANSPLANT, 68(10), 1999, pp. 1437-1443