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Results: 1-25 | 26-50 | 51-57
Results: 1-25/57
CATALYTIC PROPERTIES OF AN EXPRESSED CYTOCHROME-P450 2B1 FROM A WISTAR-KYOTO RAT-LIVER CDNA LIBRARY
Authors: KOBAYASHI Y STROBEL SM HOPKINS NE ALWORTH WL HALPERT JR
Citation: Y. Kobayashi et al., CATALYTIC PROPERTIES OF AN EXPRESSED CYTOCHROME-P450 2B1 FROM A WISTAR-KYOTO RAT-LIVER CDNA LIBRARY, Drug metabolism and disposition, 26(10), 1998, pp. 1026-1030
ANALYSIS OF HUMAN CYTOCHROME-P450 3A4 COOPERATIVITY - CONSTRUCTION AND CHARACTERIZATION OF A SITE-DIRECTED MUTANT THAT DISPLAYS HYPERBOLIC STEROID HYDROXYLATION KINETICS
Authors: HARLOW GR HALPERT JR
Citation: Gr. Harlow et Jr. Halpert, ANALYSIS OF HUMAN CYTOCHROME-P450 3A4 COOPERATIVITY - CONSTRUCTION AND CHARACTERIZATION OF A SITE-DIRECTED MUTANT THAT DISPLAYS HYPERBOLIC STEROID HYDROXYLATION KINETICS, Proceedings of the National Academy of Sciences of the United Statesof America, 95(12), 1998, pp. 6636-6641
STRUCTURE-FUNCTION-RELATIONSHIPS OF HUMAN LIVER CYTOCHROMES P450 3A -AFLATOXIN-B1 METABOLISM AS A PROBE
Authors: WANG HF DICK R YIN HQ LICADCOLES E KROETZ DL SZKLARZ G HARLOW G HALPERT JR CORREIA MA
Citation: Hf. Wang et al., STRUCTURE-FUNCTION-RELATIONSHIPS OF HUMAN LIVER CYTOCHROMES P450 3A -AFLATOXIN-B1 METABOLISM AS A PROBE, Biochemistry, 37(36), 1998, pp. 12536-12545
PROBING THE ACTIVE-SITE OF CYTOCHROME-P450 2B1 - METABOLISM OF 7-ALKOXYCOUMARINS BY THE WILD-TYPE AND 5 SITE-DIRECTED MUTANTS
Authors: KOBAYASHI Y FANG XJ SZKLARZ GD HALPERT JR
Citation: Y. Kobayashi et al., PROBING THE ACTIVE-SITE OF CYTOCHROME-P450 2B1 - METABOLISM OF 7-ALKOXYCOUMARINS BY THE WILD-TYPE AND 5 SITE-DIRECTED MUTANTS, Biochemistry, 37(19), 1998, pp. 6679-6688
ANALYSIS OF 4 RESIDUES WITHIN SUBSTRATE RECOGNITION SITE-4 OF HUMAN CYTOCHROME-P450 3A4 - ROLE IN STEROID HYDROXYLASE-ACTIVITY AND ALPHA-NAPHTHOFLAVONE STIMULATION
Authors: DOMANSKI TL LIU JP HARLOW GR HALPERT JR
Citation: Tl. Domanski et al., ANALYSIS OF 4 RESIDUES WITHIN SUBSTRATE RECOGNITION SITE-4 OF HUMAN CYTOCHROME-P450 3A4 - ROLE IN STEROID HYDROXYLASE-ACTIVITY AND ALPHA-NAPHTHOFLAVONE STIMULATION, Archives of biochemistry and biophysics, 350(2), 1998, pp. 223-232
STRUCTURAL DETERMINANTS OF PROGESTERONE HYDROXYLATION BY CYTOCHROME-P450 2B5 - THE ROLE OF NONSUBSTRATE RECOGNITION SITE RESIDUES
Authors: HE YQ HARLOW GR SZKLARZ GD HALPERT JR
Citation: Yq. He et al., STRUCTURAL DETERMINANTS OF PROGESTERONE HYDROXYLATION BY CYTOCHROME-P450 2B5 - THE ROLE OF NONSUBSTRATE RECOGNITION SITE RESIDUES, Archives of biochemistry and biophysics, 350(2), 1998, pp. 333-339
MOLECULAR MODELING OF CYTOCHROME-P450 3A4
Authors: SZKLARZ GD HALPERT JR
Citation: Gd. Szklarz et Jr. Halpert, MOLECULAR MODELING OF CYTOCHROME-P450 3A4, Journal of computer-aided molecular design, 11(3), 1997, pp. 265-272
MOLECULAR-BASIS OF P450 2B AND 3A SPECIFICITY - MUTANTS, MODELS, AND MECHANISMS
Authors: HALPERT JR DOMANSKI T FANG X HARLOW GR HE YA HE YO KOBAYASHI Y STROBEL SM SZKLARZ GD
Citation: Jr. Halpert et al., MOLECULAR-BASIS OF P450 2B AND 3A SPECIFICITY - MUTANTS, MODELS, AND MECHANISMS, The FASEB journal, 11(9), 1997, pp. 14-14
IDENTIFICATION OF KEY RESIDUES IN HUMAN CYTOCHROME-P450 3A4 BY CASSETTE, SITE-DIRECTED AND RANDOM MUTAGENESIS
Authors: HE YA HE YQ SZKLARZ GD HALPERT JR
Citation: Ya. He et al., IDENTIFICATION OF KEY RESIDUES IN HUMAN CYTOCHROME-P450 3A4 BY CASSETTE, SITE-DIRECTED AND RANDOM MUTAGENESIS, The FASEB journal, 11(9), 1997, pp. 145-145
MUTAGENESIS OF RESIDUES WITHIN SRS-2 AND SRS-4 OF HUMAN CYTOCHROME-P450 3A4 AND THE EFFECT ON HYDROXYLASE-ACTIVITY AND STIMULATION BY ALPHA-NAPHTHOFLAVONE
Authors: DOMANSKI TL HARLOW GR HALPERT JR
Citation: Tl. Domanski et al., MUTAGENESIS OF RESIDUES WITHIN SRS-2 AND SRS-4 OF HUMAN CYTOCHROME-P450 3A4 AND THE EFFECT ON HYDROXYLASE-ACTIVITY AND STIMULATION BY ALPHA-NAPHTHOFLAVONE, The FASEB journal, 11(9), 1997, pp. 147-147
HETEROLOGOUS EXPRESSION OF A P450 2B2 CDNA CLONE - ACTIVITY AND SUBSTRATE-SPECIFICITY
Authors: STROBEL SM HALPERT JR
Citation: Sm. Strobel et Jr. Halpert, HETEROLOGOUS EXPRESSION OF A P450 2B2 CDNA CLONE - ACTIVITY AND SUBSTRATE-SPECIFICITY, The FASEB journal, 11(9), 1997, pp. 148-148
STOICHIOMETRY OF 7-ETHOXYCOUMARIN METABOLISM BY WILD-TYPE P450 2B1 AND 5 ACTIVE-SITE MUTANTS
Authors: FANG X KOBAYASHI Y HALPERT JR
Citation: X. Fang et al., STOICHIOMETRY OF 7-ETHOXYCOUMARIN METABOLISM BY WILD-TYPE P450 2B1 AND 5 ACTIVE-SITE MUTANTS, The FASEB journal, 11(9), 1997, pp. 149-149
MOLECULAR-BASIS OF THE PROGESTERONE HYDROXYLASE SPECIFICITY OF CYTOCHROME-P450 2B5
Authors: HE YQ HALPERT JR
Citation: Yq. He et Jr. Halpert, MOLECULAR-BASIS OF THE PROGESTERONE HYDROXYLASE SPECIFICITY OF CYTOCHROME-P450 2B5, The FASEB journal, 11(9), 1997, pp. 151-151
SIGNIFICANCE OF GLYCINE-478 IN CYTOCHROME-P450 2B1 ON THE METABOLISM OF N-BENZYL-1-AMINOBENZOTRIAZOLE
Authors: KENT UM HANNA IH SZKLARZ GD VAZ ADN HALPERT JR BEND JR HOLLENBERG PF
Citation: Um. Kent et al., SIGNIFICANCE OF GLYCINE-478 IN CYTOCHROME-P450 2B1 ON THE METABOLISM OF N-BENZYL-1-AMINOBENZOTRIAZOLE, The FASEB journal, 11(9), 1997, pp. 187-187
ISOLATION, HETEROLOGOUS EXPRESSION, AND FUNCTIONAL-CHARACTERIZATION OF A NOVEL CYTOCHROME-P450 3A ENZYME FROM A CANINE CDNA LIBRARY
Authors: FRASER DJ FEYEREISEN R HARLOW GR HALPERT JR
Citation: Dj. Fraser et al., ISOLATION, HETEROLOGOUS EXPRESSION, AND FUNCTIONAL-CHARACTERIZATION OF A NOVEL CYTOCHROME-P450 3A ENZYME FROM A CANINE CDNA LIBRARY, The FASEB journal, 11(9), 1997, pp. 316-316
FUNCTIONAL INTERACTION BETWEEN AMINO-ACID-RESIDUE-242 AND AMINO-ACID-RESIDUE-290 IN CYTOCHROMES P-450 2B1 AND 2B11
Authors: HARLOW GR HE YA HALPERT JR
Citation: Gr. Harlow et al., FUNCTIONAL INTERACTION BETWEEN AMINO-ACID-RESIDUE-242 AND AMINO-ACID-RESIDUE-290 IN CYTOCHROMES P-450 2B1 AND 2B11, Biochimica et biophysica acta. Protein structure and molecular enzymology, 1338(2), 1997, pp. 259-266
INACTIVATION OF CYTOCHROME P450S 2B1, 2B4, 2B6, AND 2B11 BY ARYLALKYNES
Authors: ROBERTS ES HOPKINS NE FOROOZESH M ALWORTH WL HALPERT JR HOLLENBERG PF
Citation: Es. Roberts et al., INACTIVATION OF CYTOCHROME P450S 2B1, 2B4, 2B6, AND 2B11 BY ARYLALKYNES, Drug metabolism and disposition, 25(11), 1997, pp. 1242-1248
USE OF HOMOLOGY MODELING IN CONJUNCTION WITH SITE-DIRECTED MUTAGENESIS FOR ANALYSIS OF STRUCTURE-FUNCTION-RELATIONSHIPS OF MAMMALIAN CYTOCHROMES P450
Authors: SZKLARZ GD HALPERT JR
Citation: Gd. Szklarz et Jr. Halpert, USE OF HOMOLOGY MODELING IN CONJUNCTION WITH SITE-DIRECTED MUTAGENESIS FOR ANALYSIS OF STRUCTURE-FUNCTION-RELATIONSHIPS OF MAMMALIAN CYTOCHROMES P450, Life sciences, 61(26), 1997, pp. 2507-2520
ISOLATION, HETEROLOGOUS EXPRESSION AND FUNCTIONAL-CHARACTERIZATION OFA NOVEL CYTOCHROME-P450 3A ENZYME FROM A CANINE LIVER CDNA LIBRARY
Authors: FRASER DJ FEYEREISEN R HARLOW GR HALPERT JR
Citation: Dj. Fraser et al., ISOLATION, HETEROLOGOUS EXPRESSION AND FUNCTIONAL-CHARACTERIZATION OFA NOVEL CYTOCHROME-P450 3A ENZYME FROM A CANINE LIVER CDNA LIBRARY, The Journal of pharmacology and experimental therapeutics, 283(3), 1997, pp. 1425-1432
ALANINE-SCANNING MUTAGENESIS OF A PUTATIVE SUBSTRATE RECOGNITION SITEIN HUMAN CYTOCHROME-P450 3A4 - ROLE OF RESIDUE-210 AND RESIDUE-211 INFLAVONOID ACTIVATION AND SUBSTRATE-SPECIFICITY
Authors: HARLOW GR HALPERT JR
Citation: Gr. Harlow et Jr. Halpert, ALANINE-SCANNING MUTAGENESIS OF A PUTATIVE SUBSTRATE RECOGNITION SITEIN HUMAN CYTOCHROME-P450 3A4 - ROLE OF RESIDUE-210 AND RESIDUE-211 INFLAVONOID ACTIVATION AND SUBSTRATE-SPECIFICITY, The Journal of biological chemistry, 272(9), 1997, pp. 5396-5402
STOICHIOMETRY OF 7-ETHOXYCOUMARIN METABOLISM BY CYTOCHROME-P450 2B1 WILD-TYPE AND 5 ACTIVE-SITE MUTANTS
Authors: FANG XJ KOBAYASHI Y HALPERT JR
Citation: Xj. Fang et al., STOICHIOMETRY OF 7-ETHOXYCOUMARIN METABOLISM BY CYTOCHROME-P450 2B1 WILD-TYPE AND 5 ACTIVE-SITE MUTANTS, FEBS letters, 416(1), 1997, pp. 77-80
REASSESSMENT OF CYTOCHROME-P450 2B2 - CATALYTIC SPECIFICITY AND IDENTIFICATION OF 4 ACTIVE-SITE RESIDUES
Authors: STROBEL SM HALPERT JR
Citation: Sm. Strobel et Jr. Halpert, REASSESSMENT OF CYTOCHROME-P450 2B2 - CATALYTIC SPECIFICITY AND IDENTIFICATION OF 4 ACTIVE-SITE RESIDUES, Biochemistry, 36(39), 1997, pp. 11697-11706
SIGNIFICANCE OF GLYCINE-478 IN THE METABOLISM OF N-BENZYL-1-AMINOBENZOTRIAZOLE TO REACTIVE INTERMEDIATES BY CYTOCHROME-P450 2B1
Authors: KENT UM HANNA IH SZKLARZ GD VAZ ADN HALPERT JR BEND JR HOLLENBERG PF
Citation: Um. Kent et al., SIGNIFICANCE OF GLYCINE-478 IN THE METABOLISM OF N-BENZYL-1-AMINOBENZOTRIAZOLE TO REACTIVE INTERMEDIATES BY CYTOCHROME-P450 2B1, Biochemistry, 36(39), 1997, pp. 11707-11716
IDENTIFICATION OF 3 KEY RESIDUES IN SUBSTRATE RECOGNITION SITE-5 OF HUMAN CYTOCHROME-P450 3A4 BY CASSETTE AND SITE-DIRECTED MUTAGENESIS
Authors: HE YA HE YQ SZKLARZ GD HALPERT JR
Citation: Ya. He et al., IDENTIFICATION OF 3 KEY RESIDUES IN SUBSTRATE RECOGNITION SITE-5 OF HUMAN CYTOCHROME-P450 3A4 BY CASSETTE AND SITE-DIRECTED MUTAGENESIS, Biochemistry, 36(29), 1997, pp. 8831-8839
DITHIONITE-SUPPORTED HYDROXYLATION OF PALMITIC ACID BY CYTOCHROME P450BM-3
Authors: FANG XJ HALPERT JR
Citation: Xj. Fang et Jr. Halpert, DITHIONITE-SUPPORTED HYDROXYLATION OF PALMITIC ACID BY CYTOCHROME P450BM-3, Drug metabolism and disposition, 24(11), 1996, pp. 1282-1285
Risultati: 1-25 | 26-50 | 51-57