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Results: 76-100/110
AZATOXIN DERIVATIVES WITH POTENT AND SELECTIVE ACTION ON TOPOISOMERASE-II
Authors: LETEURTRE F SACKETT DL MADALENGOITIA J KOHLHAGEN G MACDONALD T HAMEL E PAULL KD POMMIER Y
Citation: F. Leteurtre et al., AZATOXIN DERIVATIVES WITH POTENT AND SELECTIVE ACTION ON TOPOISOMERASE-II, Biochemical pharmacology, 49(9), 1995, pp. 1283-1290
INTERACTIONS OF TUBULIN WITH GUANINE-NUCLEOTIDES THAT HAVE PACLITAXEL-LIKE EFFECTS ON TUBULIN ASSEMBLY - 2',3'-DIDEOXYGUANOSINE 5'-[ALPHA,BETA-METHYLENE]TRIPHOSPHATE GUANOINE 5'-[ALPHA,BETA-METHYLENE]TRIPHOSPHATE, AND 2',3'-DIDEOXYGUANOSINE 5'-TRIPHOSPHATE
Authors: HAMEL E VAUGHNS J GETAHUN Z JOHNSON R LIN CM
Citation: E. Hamel et al., INTERACTIONS OF TUBULIN WITH GUANINE-NUCLEOTIDES THAT HAVE PACLITAXEL-LIKE EFFECTS ON TUBULIN ASSEMBLY - 2',3'-DIDEOXYGUANOSINE 5'-[ALPHA,BETA-METHYLENE]TRIPHOSPHATE GUANOINE 5'-[ALPHA,BETA-METHYLENE]TRIPHOSPHATE, AND 2',3'-DIDEOXYGUANOSINE 5'-TRIPHOSPHATE, Archives of biochemistry and biophysics, 322(2), 1995, pp. 486-499
REGIOCONTROLLED TOTAL SYNTHESES OF THE TROPOLOISOQUINOLINE ALKALOIDS IMERUBRINE AND GRANDIRUBRINE
Authors: BANWELL MG HAMEL E IRELAND NK MACKAY MF
Citation: Mg. Banwell et al., REGIOCONTROLLED TOTAL SYNTHESES OF THE TROPOLOISOQUINOLINE ALKALOIDS IMERUBRINE AND GRANDIRUBRINE, Heterocycles, 39(1), 1994, pp. 205-217
SYNTHESIS AND BIOLOGICAL EVALUATION OF 4-DEACETYLPACLITAXEL
Authors: NEIDIGH KA GHARPURE MM RIMOLDI JM KINGSTON DGI JIANG YQ HAMEL E
Citation: Ka. Neidigh et al., SYNTHESIS AND BIOLOGICAL EVALUATION OF 4-DEACETYLPACLITAXEL, Tetrahedron letters, 35(37), 1994, pp. 6839-6842
SYNTHESIS AND BIOLOGICAL EVALUATION OF 4-DEACETOXYPACLITAXEL
Authors: CHORDIA MD CHAUDHARY AG KINGSTON DGI JIANG YQ HAMEL E
Citation: Md. Chordia et al., SYNTHESIS AND BIOLOGICAL EVALUATION OF 4-DEACETOXYPACLITAXEL, Tetrahedron letters, 35(37), 1994, pp. 6843-6846
2-METHOXYESTRADIOL, AN ENDOGENOUS MAMMALIAN METABOLITE, INHIBITS TUBULIN POLYMERIZATION BY INTERACTING AT THE COLCHICINE SITE
Authors: DAMATO RJ LIN CM FLYNN E FOLKMAN J HAMEL E
Citation: Rj. Damato et al., 2-METHOXYESTRADIOL, AN ENDOGENOUS MAMMALIAN METABOLITE, INHIBITS TUBULIN POLYMERIZATION BY INTERACTING AT THE COLCHICINE SITE, Proceedings of the National Academy of Sciences of the United Statesof America, 91(9), 1994, pp. 3964-3968
TOTAL SYNTHESES OF THE STRUCTURES ASSIGNED TO SALIMINE AND JERUSALEMINE, ALKALOIDS FROM COLCHICUM-DECAISNEI BOISS (LILIACEAE)
Authors: BANWELL MG FAM MA GABLE RW HAMEL E
Citation: Mg. Banwell et al., TOTAL SYNTHESES OF THE STRUCTURES ASSIGNED TO SALIMINE AND JERUSALEMINE, ALKALOIDS FROM COLCHICUM-DECAISNEI BOISS (LILIACEAE), Journal of the Chemical Society, Chemical Communications, (22), 1994, pp. 2647-2649
ANTINEOPLASTIC AGENTS-300 - ISOLATION AND STRUCTURE OF THE RARE HUMANCANCER INHIBITORY MACROCYCLIC LACTONES SPONGISTATIN-8 AND SPONGISTATIN-9
Authors: PETTIT GR CICHACZ ZA HERALD CL GAO F BOYD MR SCHMIDT JM HAMEL E BAI RL
Citation: Gr. Pettit et al., ANTINEOPLASTIC AGENTS-300 - ISOLATION AND STRUCTURE OF THE RARE HUMANCANCER INHIBITORY MACROCYCLIC LACTONES SPONGISTATIN-8 AND SPONGISTATIN-9, Journal of the Chemical Society, Chemical Communications, (13), 1994, pp. 1605-1606
STRUCTURE OF CURACIN-A, A NOVEL ANTIMITOTIC, ANTIPROLIFERATIVE, AND BRINE SHRIMP TOXIC NATURAL PRODUCT FROM THE MARINE CYANOBACTERIUM LYNGBYA-MAJUSCULA
Authors: GERWICK WH PROTEAU PJ NAGLE DG HAMEL E BLOKHIN A SLATE DL
Citation: Wh. Gerwick et al., STRUCTURE OF CURACIN-A, A NOVEL ANTIMITOTIC, ANTIPROLIFERATIVE, AND BRINE SHRIMP TOXIC NATURAL PRODUCT FROM THE MARINE CYANOBACTERIUM LYNGBYA-MAJUSCULA, Journal of organic chemistry, 59(6), 1994, pp. 1243-1245
THE DOLASTATINS .21. SYNTHESIS, X-RAY CRYSTAL-STRUCTURE, AND MOLECULAR MODELING OF (6R)-ISODOLASTATIN-10
Authors: PETTIT GR SRIRANGAM JK HERALD DL HAMEL E
Citation: Gr. Pettit et al., THE DOLASTATINS .21. SYNTHESIS, X-RAY CRYSTAL-STRUCTURE, AND MOLECULAR MODELING OF (6R)-ISODOLASTATIN-10, Journal of organic chemistry, 59(21), 1994, pp. 6127-6130
CHOLINERGIC DILATATION AND CONSTRICTION OF FELINE CEREBRAL BLOOD-VESSELS ARE MEDIATED BY STIMULATION OF PHOSPHOINOSITIDE METABOLISM VIA 2 DIFFERENT MUSCARINIC RECEPTOR SUBTYPES
Authors: DAUPHIN F LINVILLE DG HAMEL E
Citation: F. Dauphin et al., CHOLINERGIC DILATATION AND CONSTRICTION OF FELINE CEREBRAL BLOOD-VESSELS ARE MEDIATED BY STIMULATION OF PHOSPHOINOSITIDE METABOLISM VIA 2 DIFFERENT MUSCARINIC RECEPTOR SUBTYPES, Journal of neurochemistry, 63(2), 1994, pp. 544-551
ANTITUMOR AGENTS .150. 2',3',4',5',5,6,7-SUBSTITUTED 2-PHENYL-4-QUINOLONES AND RELATED-COMPOUNDS - THEIR SYNTHESIS, CYTOTOXICITY, AND INHIBITION OF TUBULIN POLYMERIZATION
Authors: LI L WANG HK KUO SC WU TS LEDNICER D LIN CM HAMEL E LEE KH
Citation: L. Li et al., ANTITUMOR AGENTS .150. 2',3',4',5',5,6,7-SUBSTITUTED 2-PHENYL-4-QUINOLONES AND RELATED-COMPOUNDS - THEIR SYNTHESIS, CYTOTOXICITY, AND INHIBITION OF TUBULIN POLYMERIZATION, Journal of medicinal chemistry, 37(8), 1994, pp. 1126-1135
ANTITUMOR AGENTS .155. SYNTHESIS AND BIOLOGICAL EVALUATION OF 3',6,7-SUBSTITUTED 2-PHENYL-4-QUINOLONES AS ANTIMICROTUBULE AGENTS
Authors: LI LP WANG HK KUO SC WU TS MAUGER A LIN CM HAMEL E LEE KH
Citation: Lp. Li et al., ANTITUMOR AGENTS .155. SYNTHESIS AND BIOLOGICAL EVALUATION OF 3',6,7-SUBSTITUTED 2-PHENYL-4-QUINOLONES AS ANTIMICROTUBULE AGENTS, Journal of medicinal chemistry, 37(20), 1994, pp. 3400-3407
LIGHT AND ELECTRON-MICROSCOPIC IMMUNOCYTOCHEMICAL ANALYSIS OF THE NEUROVASCULAR RELATIONSHIPS OF CHOLINE-ACETYLTRANSFERASE AND VASOACTIVE INTESTINAL POLYPEPTIDE NERVE-TERMINALS IN THE RAT CEREBRAL CARTER
Authors: CHEDOTAL A UMBRIACO D DESCARRIES L HARTMAN BK HAMEL E
Citation: A. Chedotal et al., LIGHT AND ELECTRON-MICROSCOPIC IMMUNOCYTOCHEMICAL ANALYSIS OF THE NEUROVASCULAR RELATIONSHIPS OF CHOLINE-ACETYLTRANSFERASE AND VASOACTIVE INTESTINAL POLYPEPTIDE NERVE-TERMINALS IN THE RAT CEREBRAL CARTER, Journal of comparative neurology, 343(1), 1994, pp. 57-71
THE MAGNESIUM-GTP, INTERACTION IN MICROTUBULE ASSEMBLY
Authors: GROVER S HAMEL E
Citation: S. Grover et E. Hamel, THE MAGNESIUM-GTP, INTERACTION IN MICROTUBULE ASSEMBLY, European journal of biochemistry, 222(1), 1994, pp. 163-172
DISTINCT CHOLINE-ACETYLTRANSFERASE (CHAT) AND VASOACTIVE INTESTINAL POLYPEPTIDE (VIP) BIPOLAR NEURONS PROJECT TO LOCAL BLOOD-VESSELS IN THERAT CEREBRAL-CORTEX
Authors: CHEDOTAL A COZZARI C FAURE MP HARTMAN BK HAMEL E
Citation: A. Chedotal et al., DISTINCT CHOLINE-ACETYLTRANSFERASE (CHAT) AND VASOACTIVE INTESTINAL POLYPEPTIDE (VIP) BIPOLAR NEURONS PROJECT TO LOCAL BLOOD-VESSELS IN THERAT CEREBRAL-CORTEX, Brain research, 646(2), 1994, pp. 181-193
UNEXPECTEDLY FACILE HYDROLYSIS OF THE 2-BENZOATE GROUP OF TAXOL AND SYNTHESES OF ANALOGS WITH INCREASED ACTIVITIES
Authors: CHAUDHARY AG GHARPURE MM RIMOLDI JM CHORDIA MD GUNATILAKA AAL KINGSTON DGI GROVER S LIN CM HAMEL E
Citation: Ag. Chaudhary et al., UNEXPECTEDLY FACILE HYDROLYSIS OF THE 2-BENZOATE GROUP OF TAXOL AND SYNTHESES OF ANALOGS WITH INCREASED ACTIVITIES, Journal of the American Chemical Society, 116(9), 1994, pp. 4097-4098
CHOLINERGIC INNERVATION OF THE VASCULAR W ALL
Authors: CHEDOTAL A HAMEL E
Citation: A. Chedotal et E. Hamel, CHOLINERGIC INNERVATION OF THE VASCULAR W ALL, MS. Medecine sciences, 9(10), 1993, pp. 1035-1042
STUDIES DIRECTED TOWARDS TOTAL SYNTHESES OF THE TROPOLOISOQUINOLINE ALKALOIDS GRANDIRUBRINE AND IMERUBRINE .2. THERMOLYSIS OF TRAMETHOXYISOQUINO[2,1-C][1,2,3]BENZOTRIAZIN-7-IUM CHLORIDE - COMPETITIVE MODES OF CYCLIZATION LEADING TO THE INDENO[1,2,3-IJ]ISOQUINOLINE (AZAFLUORANTHENE) SKELETON
Authors: BANWELL MG HAMEL E IRELAND NK MACKAY MF SERELIS AK
Citation: Mg. Banwell et al., STUDIES DIRECTED TOWARDS TOTAL SYNTHESES OF THE TROPOLOISOQUINOLINE ALKALOIDS GRANDIRUBRINE AND IMERUBRINE .2. THERMOLYSIS OF TRAMETHOXYISOQUINO[2,1-C][1,2,3]BENZOTRIAZIN-7-IUM CHLORIDE - COMPETITIVE MODES OF CYCLIZATION LEADING TO THE INDENO[1,2,3-IJ]ISOQUINOLINE (AZAFLUORANTHENE) SKELETON, Journal of the Chemical Society. Perkin transactions. I, (16), 1993, pp. 1905-1911
MODIFIED TAXOLS .9. SYNTHESIS AND BIOLOGICAL EVALUATION OF 7-SUBSTITUTED PHOTOAFFINITY ANALOGS OF TAXOL
Authors: RIMOLDI JM KINGSTON DGI CHAUDHARY AG SAMARANAYAKE G GROVER S HAMEL E
Citation: Jm. Rimoldi et al., MODIFIED TAXOLS .9. SYNTHESIS AND BIOLOGICAL EVALUATION OF 7-SUBSTITUTED PHOTOAFFINITY ANALOGS OF TAXOL, Journal of natural products, 56(8), 1993, pp. 1313-1330
2 NEW CYTOTOXIC CHALCONES FROM CALYTHROPSIS-AUREA
Authors: BEUTLER JA CARDELLINA JH GRAY GN PRATHER TR SHOEMAKER RH BOYD MR LIN CM HAMEL E CRAGG GM
Citation: Ja. Beutler et al., 2 NEW CYTOTOXIC CHALCONES FROM CALYTHROPSIS-AUREA, Journal of natural products, 56(10), 1993, pp. 1718-1722
SPONGISTATIN-1, A HIGHLY CYTOTOXIC, SPONGE-DERIVED, MARINE NATURAL PRODUCT THAT INHIBITS MITOSIS, MICROTUBULE ASSEMBLY, AND THE BINDING OF VINBLASTINE TO TUBULIN
Authors: BAI RL CICHACZ ZA HERALD CL PETTIT GR HAMEL E
Citation: Rl. Bai et al., SPONGISTATIN-1, A HIGHLY CYTOTOXIC, SPONGE-DERIVED, MARINE NATURAL PRODUCT THAT INHIBITS MITOSIS, MICROTUBULE ASSEMBLY, AND THE BINDING OF VINBLASTINE TO TUBULIN, Molecular pharmacology, 44(4), 1993, pp. 757-766
EXPRESSION OF MESSENGER-RNA FOR THE SEROTONIN 5-HYDROXYTRYPTAMINE(1D-BETA) RECEPTOR SUBTYPE IN HUMAN AND BOVINE CEREBRAL-ARTERIES
Authors: HAMEL E FAN E LINVILLE D TING V VILLEMURE JG CHIA LS
Citation: E. Hamel et al., EXPRESSION OF MESSENGER-RNA FOR THE SEROTONIN 5-HYDROXYTRYPTAMINE(1D-BETA) RECEPTOR SUBTYPE IN HUMAN AND BOVINE CEREBRAL-ARTERIES, Molecular pharmacology, 44(2), 1993, pp. 242-246
ISOLATION AND STRUCTURE OF HALISTATIN-1 FROM THE EASTERN INDIAN-OCEANMARINE SPONGE PHAKELLIA-CARTERI
Authors: PETTIT GR TAN R GAO F WILLIAMS MD DOUBEK DL BOYD MR SCHMIDT JM CHAPUIS JC HAMEL E BAI R HOOPER JNA TACKETT LP
Citation: Gr. Pettit et al., ISOLATION AND STRUCTURE OF HALISTATIN-1 FROM THE EASTERN INDIAN-OCEANMARINE SPONGE PHAKELLIA-CARTERI, Journal of organic chemistry, 58(9), 1993, pp. 2538-2543
SYNTHESIS AND CYTOTOXICITY OF 1,6,7,8-SUBSTITUTED 2-(4'SUBSTITUTED PHENYL)-4-QUINOLONES AND RELATED-COMPOUNDS - IDENTIFICATION AS ANTIMITOTIC AGENTS INTERACTING WITH TUBULIN
Authors: KUO SC LEE HZ JUANG JP LIN YT WU TS CHANG JJ LEDNICER D PAULL KD LIN CM HAMEL E LEE KH
Citation: Sc. Kuo et al., SYNTHESIS AND CYTOTOXICITY OF 1,6,7,8-SUBSTITUTED 2-(4'SUBSTITUTED PHENYL)-4-QUINOLONES AND RELATED-COMPOUNDS - IDENTIFICATION AS ANTIMITOTIC AGENTS INTERACTING WITH TUBULIN, Journal of medicinal chemistry, 36(9), 1993, pp. 1146-1156
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