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Results: 1-25 |
Results: 25
SUBSTITUTED 3-BETA-PHENYLETHYNYL DERIVATIVES OF 3-ALPHA-HYDROXY-5-ALPHA-PREGNAN-20-ONE - REMARKABLY POTENT NEUROACTIVE STEROID MODULATORS OF GAMMA-AMINOBUTYRIC ACID(A) RECEPTORS
Authors: HAWKINSON JE ACOSTABURRUEL M YANG KC HOGENKAMP DJ CHEN JS LAN NC DREWE JA WHITTEMORE ER WOODWARD RM CARTER RB UPASANI RB
Citation: Je. Hawkinson et al., SUBSTITUTED 3-BETA-PHENYLETHYNYL DERIVATIVES OF 3-ALPHA-HYDROXY-5-ALPHA-PREGNAN-20-ONE - REMARKABLY POTENT NEUROACTIVE STEROID MODULATORS OF GAMMA-AMINOBUTYRIC ACID(A) RECEPTORS, The Journal of pharmacology and experimental therapeutics, 287(1), 1998, pp. 198-207
ANXIOLYTIC AND ANTICONVULSANT ACTIVITY OF A SYNTHETIC NEUROACTIVE STEROID CO-3-0593
Authors: WIELAND S BELLUZZI J HAWKINSON JE HOGENKAMP D UPASANI R STEIN L WOOD PL GEE KW LAN NC
Citation: S. Wieland et al., ANXIOLYTIC AND ANTICONVULSANT ACTIVITY OF A SYNTHETIC NEUROACTIVE STEROID CO-3-0593, Psychopharmacology, 134(1), 1997, pp. 46-54
CCD-3693 - AN ORALLY BIOAVAILABLE ANALOG OF THE ENDOGENOUS NEUROACTIVE STEROID, PREGNANOLONE, DEMONSTRATES POTENT SEDATIVE HYPNOTIC ACTIONSIN THE RAT
Authors: EDGAR DM SEIDEL WF GEE KW LAN NC FIELD G XIA HJ HAWKINSON JE WIELAND S CARTER RB WOOD PL
Citation: Dm. Edgar et al., CCD-3693 - AN ORALLY BIOAVAILABLE ANALOG OF THE ENDOGENOUS NEUROACTIVE STEROID, PREGNANOLONE, DEMONSTRATES POTENT SEDATIVE HYPNOTIC ACTIONSIN THE RAT, The Journal of pharmacology and experimental therapeutics, 282(1), 1997, pp. 420-429
CHARACTERIZATION OF THE ANTICONVULSANT PROPERTIES OF GANAXOLONE (CCD 1042, PHA-HYDROXY-3-BETA-METHYL-5-ALPHA-PREGNAN-20-ONE), A SELECTIVE, HIGH-AFFINITY, STEROID MODULATOR OF THE GAMMA-AMINOBUTYRIC ACID(A) RECEPTOR
Authors: CARTER RB WOOD PL WIELAND S HAWKINSON JE BELELLI D LAMBERT JJ WHITE HS WOLF HH MIRSADEGHI S TAHIR SH BOLGER MB LAN NC GEE KW
Citation: Rb. Carter et al., CHARACTERIZATION OF THE ANTICONVULSANT PROPERTIES OF GANAXOLONE (CCD 1042, PHA-HYDROXY-3-BETA-METHYL-5-ALPHA-PREGNAN-20-ONE), A SELECTIVE, HIGH-AFFINITY, STEROID MODULATOR OF THE GAMMA-AMINOBUTYRIC ACID(A) RECEPTOR, The Journal of pharmacology and experimental therapeutics, 280(3), 1997, pp. 1284-1295
STRUCTURE-ACTIVITY-RELATIONSHIPS OF ALKYL-SUBSTITUTED AND ALKOXY-SUBSTITUTED 1,4-DIHYDROQUINOXALINE-2,3-DIONES - POTENT AND SYSTEMICALLY ACTIVE ANTAGONISTS FOR THE GLYCINE SITE OF THE NMDA RECEPTOR
Authors: CAI SX KHER SM ZHOU ZL ILYIN V ESPITIA SA TRAN M HAWKINSON JE WOODWARD RM WEBER E KEANA JFW
Citation: Sx. Cai et al., STRUCTURE-ACTIVITY-RELATIONSHIPS OF ALKYL-SUBSTITUTED AND ALKOXY-SUBSTITUTED 1,4-DIHYDROQUINOXALINE-2,3-DIONES - POTENT AND SYSTEMICALLY ACTIVE ANTAGONISTS FOR THE GLYCINE SITE OF THE NMDA RECEPTOR, Journal of medicinal chemistry, 40(5), 1997, pp. 730-738
A)-7-SUBSTITUTED-1,4-DIHYDROQUINOXALINE-2,3-DIONES - NOVEL, SYSTEMICALLY ACTIVE AND BROAD-SPECTRUM ANTAGONISTS FOR NMDA GLYCINE, AMPA, AND KAINATE RECEPTORS/
Authors: CAI SX HUANG JC ESPITIA SA TRAN M ILYIN VI HAWKINSON JE WOODWARD RM WEBER E KEANA JFW
Citation: Sx. Cai et al., A)-7-SUBSTITUTED-1,4-DIHYDROQUINOXALINE-2,3-DIONES - NOVEL, SYSTEMICALLY ACTIVE AND BROAD-SPECTRUM ANTAGONISTS FOR NMDA GLYCINE, AMPA, AND KAINATE RECEPTORS/, Journal of medicinal chemistry, 40(22), 1997, pp. 3679-3686
SYNTHESIS AND IN-VITRO ACTIVITY OF 3-BETA-SUBSTITUTED-3-ALPHA-HYDROXYPREGNAN-20-ONES - ALLOSTERIC MODULATORS OF THE GABA(A) RECEPTOR
Authors: HOGENKAMP DJ TAHIR SH HAWKINSON JE UPASANI RB ALAUDDIN M KIMBROUGH CL ACOSTABURRUEL M WHITTEMORE ER WOODWARD RM LAN NC GEE KW BOLGER MB
Citation: Dj. Hogenkamp et al., SYNTHESIS AND IN-VITRO ACTIVITY OF 3-BETA-SUBSTITUTED-3-ALPHA-HYDROXYPREGNAN-20-ONES - ALLOSTERIC MODULATORS OF THE GABA(A) RECEPTOR, Journal of medicinal chemistry, 40(1), 1997, pp. 61-72
ROXY-3-BETA-(PHENYLETHYNYL)-5-BETA-PREGNAN-20-ONES - SYNTHESIS AND PHARMACOLOGICAL ACTIVITY OF NEUROACTIVE STEROIDS WITH HIGH-AFFINITY FOR GABA(A) RECEPTORS
Authors: UPASANI RB YANG KC ACOSTABURRUEL M KONKOY CS MCLELLAN JA WOODWARD RM LAN NC CARTER RB HAWKINSON JE
Citation: Rb. Upasani et al., ROXY-3-BETA-(PHENYLETHYNYL)-5-BETA-PREGNAN-20-ONES - SYNTHESIS AND PHARMACOLOGICAL ACTIVITY OF NEUROACTIVE STEROIDS WITH HIGH-AFFINITY FOR GABA(A) RECEPTORS, Journal of medicinal chemistry, 40(1), 1997, pp. 73-84
NOVEL PHOSPHOSERINE PHOSPHATASE INHIBITORS
Authors: HAWKINSON JE ACOSTABURRUEL M TA ND WOOD PL
Citation: Je. Hawkinson et al., NOVEL PHOSPHOSERINE PHOSPHATASE INHIBITORS, European journal of pharmacology, 337(2-3), 1997, pp. 315-324
EFFECTS OF THIOCYANATE AND AMPA RECEPTOR LIGANDS ON (S)-5-FLUOROWILLARDIINE, (S)-AMPA AND (R,S)-AMPA BINDING
Authors: HAWKINSON JE ESPITIA SA
Citation: Je. Hawkinson et Sa. Espitia, EFFECTS OF THIOCYANATE AND AMPA RECEPTOR LIGANDS ON (S)-5-FLUOROWILLARDIINE, (S)-AMPA AND (R,S)-AMPA BINDING, European journal of pharmacology, 329(2-3), 1997, pp. 213-221
THE N-METHYL-D-ASPARTATE (NMDA) RECEPTOR GLYCINE SITE ANTAGONIST ACEA-1021 DOES NOT PRODUCE PATHOLOGICAL-CHANGES IN RAT-BRAIN
Authors: HAWKINSON JE HUBER KR SAHOTA PS HSU HH WEBER E WHITEHOUSE MJ
Citation: Je. Hawkinson et al., THE N-METHYL-D-ASPARTATE (NMDA) RECEPTOR GLYCINE SITE ANTAGONIST ACEA-1021 DOES NOT PRODUCE PATHOLOGICAL-CHANGES IN RAT-BRAIN, Brain research, 744(2), 1997, pp. 227-234
1-HYDROXY-1,4-DIHYDROQUINOXALINE-2,3-DIONES - NOVEL ANTAGONISTS AT NMDA RECEPTOR GLYCINE SITES
Authors: ZHENG H ESPITIA SA ILYIN V HAWKINSON JE WOODWARD RM WEBER E KEANA JFW
Citation: H. Zheng et al., 1-HYDROXY-1,4-DIHYDROQUINOXALINE-2,3-DIONES - NOVEL ANTAGONISTS AT NMDA RECEPTOR GLYCINE SITES, Bioorganic & medicinal chemistry letters, 6(4), 1996, pp. 439-440
IN-VITRO AND IN-VIVO ACTIVITY OF 16,17-DEHYDRO-EPIPREGNANOLONES - 17,20-BOND TORSIONAL ENERGY ANALYSIS AND D-RING CONFORMATION
Authors: BOLGER MB WIELAND S HAWKINSON JE XIA HJ UPASANI R LAN NC
Citation: Mb. Bolger et al., IN-VITRO AND IN-VIVO ACTIVITY OF 16,17-DEHYDRO-EPIPREGNANOLONES - 17,20-BOND TORSIONAL ENERGY ANALYSIS AND D-RING CONFORMATION, Pharmaceutical research, 13(10), 1996, pp. 1488-1494
ROXY-3-BETA-TRIFLUOROMETHYL-5-ALPHA-PREGNAN-20-ONE (CO-2-1970) - A PARTIAL AGONIST AT THE NEUROACTIVE STEROID SITE OF THE GAMMA-AMINOBUTYRIC-ACID(A) RECEPTOR
Authors: HAWKINSON JE DREWE JA KIMBROUGH CL CHEN JS HOGENKAMP DJ LAN NC GEE KW SHEN KZ WHITTEMORE ER WOODWARD RM
Citation: Je. Hawkinson et al., ROXY-3-BETA-TRIFLUOROMETHYL-5-ALPHA-PREGNAN-20-ONE (CO-2-1970) - A PARTIAL AGONIST AT THE NEUROACTIVE STEROID SITE OF THE GAMMA-AMINOBUTYRIC-ACID(A) RECEPTOR, Molecular pharmacology, 49(5), 1996, pp. 897-906
FORMATION OF D-SERINE FROM L-PHOSPHOSERINE IN BRAIN SYNAPTOSOMES
Authors: WOOD PL HAWKINSON JE GOODNOUGH DB
Citation: Pl. Wood et al., FORMATION OF D-SERINE FROM L-PHOSPHOSERINE IN BRAIN SYNAPTOSOMES, Journal of neurochemistry, 67(4), 1996, pp. 1485-1490
ANALOGS OF 3-HYDROXY-1H-1-BENZAZEPINE-2,5-DIONE - STRUCTURE-ACTIVITY RELATIONSHIP AT N-METHYL-D-ASPARTATE RECEPTOR GLYCINE SITES
Authors: GUZIKOWSKI AP CAI SX ESPITIA SA HAWKINSON JE HUETTNER JE NOGALES DF TRAN M WOODWARD RM WEBER E KEANA JFW
Citation: Ap. Guzikowski et al., ANALOGS OF 3-HYDROXY-1H-1-BENZAZEPINE-2,5-DIONE - STRUCTURE-ACTIVITY RELATIONSHIP AT N-METHYL-D-ASPARTATE RECEPTOR GLYCINE SITES, Journal of medicinal chemistry, 39(23), 1996, pp. 4643-4653
STRUCTURE-ACTIVITY RELATIONSHIPS OF 4-HYDROXY-3-NITROQUINOLIN-2(1H)-ONES AS NOVEL ANTAGONISTS AT THE GLYCINE SITE OF N-METHYL-D-ASPARTATE RECEPTORS
Authors: CAI SX ZHOU ZL HUANG JC WHITTEMORE ER EGBUWOKU ZO HAWKINSON JE WOODWARD RM WEBER E KEANA JFW
Citation: Sx. Cai et al., STRUCTURE-ACTIVITY RELATIONSHIPS OF 4-HYDROXY-3-NITROQUINOLIN-2(1H)-ONES AS NOVEL ANTAGONISTS AT THE GLYCINE SITE OF N-METHYL-D-ASPARTATE RECEPTORS, Journal of medicinal chemistry, 39(23), 1996, pp. 4682-4686
SYNTHESIS AND STRUCTURE-ACTIVITY-RELATIONSHIPS OF 1,2,3,4-TETRAHYDROQUINOLINE-2,3,4-TRIONE 3-OXIMES - NOVEL AND HIGHLY POTENT ANTAGONISTS FOR NMDA RECEPTOR GLYCINE SITE
Authors: CAI SX ZHOU ZL HUANG JC WHITTEMORE ER EGBUWOKU ZO LU YX HAWKINSON JE WOODWARD RM WEBER E KEANA JFW
Citation: Sx. Cai et al., SYNTHESIS AND STRUCTURE-ACTIVITY-RELATIONSHIPS OF 1,2,3,4-TETRAHYDROQUINOLINE-2,3,4-TRIONE 3-OXIMES - NOVEL AND HIGHLY POTENT ANTAGONISTS FOR NMDA RECEPTOR GLYCINE SITE, Journal of medicinal chemistry, 39(17), 1996, pp. 3248-3255
THE METABOTROPIC GLUTAMATE-RECEPTOR ANTAGONIST L-2-AMINO-3-PHOSPHONOPROPIONIC ACID INHIBITS PHOSPHOSERINE PHOSPHATASE
Authors: HAWKINSON JE ACOSTABURRUEL M WOOD PL
Citation: Je. Hawkinson et al., THE METABOTROPIC GLUTAMATE-RECEPTOR ANTAGONIST L-2-AMINO-3-PHOSPHONOPROPIONIC ACID INHIBITS PHOSPHOSERINE PHOSPHATASE, European journal of pharmacology, 307(2), 1996, pp. 219-225
STEROID INHIBITION OF [H-3]SR-95531 BINDING TO THE GABA(A) RECOGNITION SITE
Authors: HAWKINSON JE ACOSTABURRUEL M KIMBROUGH CL GOODNOUGH DB WOOD PL
Citation: Je. Hawkinson et al., STEROID INHIBITION OF [H-3]SR-95531 BINDING TO THE GABA(A) RECOGNITION SITE, European journal of pharmacology, 304(1-3), 1996, pp. 141-146
NEUROACTIVE STEROID MODULATION OF [H-3] MUSCIMOL BINDING TO THE GABA(A) RECEPTOR COMPLEX IN RAT CORTEX
Authors: GOODNOUGH DB HAWKINSON JE
Citation: Db. Goodnough et Je. Hawkinson, NEUROACTIVE STEROID MODULATION OF [H-3] MUSCIMOL BINDING TO THE GABA(A) RECEPTOR COMPLEX IN RAT CORTEX, European journal of pharmacology. Molecular pharmacology section, 288(2), 1995, pp. 157-162
SELECTIVE ACTIONS OF CERTAIN NEUROACTIVE PREGNANEDIOLS AT THE GAMMA-AMINOBUTYRIC-ACID TYPE-A RECEPTOR COMPLEX IN RAT-BRAIN
Authors: MCCAULEY LD LIU V CHEN JS HAWKINSON JE LAN NC GEE KW
Citation: Ld. Mccauley et al., SELECTIVE ACTIONS OF CERTAIN NEUROACTIVE PREGNANEDIOLS AT THE GAMMA-AMINOBUTYRIC-ACID TYPE-A RECEPTOR COMPLEX IN RAT-BRAIN, Molecular pharmacology, 47(2), 1995, pp. 354-362
THE NEUROACTIVE STEROID 3-ALPHA-HYDROXY-5-BETA-PREGNAN-20-ONE IS A 2-COMPONENT MODULATOR OF LIGAND-BINDING TO THE GABA(A) RECEPTOR
Authors: HAWKINSON JE KIMBROUGH CL MCCAULEY LD BOLGER MB LAN NC GEE KW
Citation: Je. Hawkinson et al., THE NEUROACTIVE STEROID 3-ALPHA-HYDROXY-5-BETA-PREGNAN-20-ONE IS A 2-COMPONENT MODULATOR OF LIGAND-BINDING TO THE GABA(A) RECEPTOR, European journal of pharmacology. Molecular pharmacology section, 269(2), 1994, pp. 157-163
CORRELATION OF NEUROACTIVE STEROID MODULATION OF [S-35] T-BUTYLBICYCLOPHOSPHOROTHIONATE AND [H-3] FLUNITRAZEPAM BINDING AND GAMMA-AMINOBUTYRIC-ACID, RECEPTOR FUNCTION
Authors: HAWKINSON JE KIMBROUGH CL BELELLI D LAMBERT JJ PURDY RH LAN NC
Citation: Je. Hawkinson et al., CORRELATION OF NEUROACTIVE STEROID MODULATION OF [S-35] T-BUTYLBICYCLOPHOSPHOROTHIONATE AND [H-3] FLUNITRAZEPAM BINDING AND GAMMA-AMINOBUTYRIC-ACID, RECEPTOR FUNCTION, Molecular pharmacology, 46(5), 1994, pp. 977-985
PHOTOACTIVATABLE LUOROPHENYL)-5-TERT-BUTYL-1,3-DITHIANE-BIS-SULFONE AND RELATED-COMPOUNDS AS CANDIDATE IRREVERSIBLE PROBES FOR THE GABA-GATED CHLORIDE CHANNELS
Authors: KAPFER I HAWKINSON JE CASIDA JE GOELDNER MP
Citation: I. Kapfer et al., PHOTOACTIVATABLE LUOROPHENYL)-5-TERT-BUTYL-1,3-DITHIANE-BIS-SULFONE AND RELATED-COMPOUNDS AS CANDIDATE IRREVERSIBLE PROBES FOR THE GABA-GATED CHLORIDE CHANNELS, Journal of medicinal chemistry, 37(1), 1994, pp. 133-140
Risultati: 1-25 |