Authors:
DEHAAN L
VERWEIJ WR
FEIL IK
HOLTROP M
HOL WGJ
AGSTERIBBE E
WILSCHUT J
Citation: L. Dehaan et al., NONTOXIC VARIANTS OF THE ESCHERICHIA-COLI HEAT-LABILE ENTEROTOXIN AS MUCOSAL IMMUNOGENS AND ADJUVANTS, STP PHARMA SCIENCES, 8(1), 1998, pp. 75-80
Authors:
BERNSTEIN BE
MICHELS PAM
KIM HD
PETRA PH
HOL WGJ
Citation: Be. Bernstein et al., THE IMPORTANCE OF DYNAMIC LIGHT-SCATTERING IN OBTAINING MULTIPLE CRYSTAL FORMS OF TRYPANOSOMA-BRUCEI PGK, Protein science, 7(2), 1998, pp. 504-507
Citation: Ji. Yeh et Wgj. Hol, A FLASH-ANNEALING TECHNIQUE TO IMPROVE DIFFRACTION LIMITS AND LOWER MOSAICITY IN CRYSTALS OF GLYCEROL KINASE, Acta crystallographica. Section D, Biological crystallography, 54, 1998, pp. 479-480
Authors:
CHANDRA NR
MUIRHEAD H
HOLBROOK JJ
BERNSTEIN BE
HOL WGJ
SESSIONS RB
Citation: Nr. Chandra et al., A GENERAL-METHOD OF DOMAIN CLOSURE IS APPLIED TO PHOSPHOGLYCERATE KINASE AND THE RESULT COMPARED WITH THE CRYSTAL-STRUCTURE OF A CLOSED CONFORMATION OF THE ENZYME, Proteins, 30(4), 1998, pp. 372-380
Authors:
REDINBO MR
STEWART L
KUHN P
CHAMPOUX JJ
HOL WGJ
Citation: Mr. Redinbo et al., CRYSTAL-STRUCTURES OF HUMAN TOPOISOMERASE-I IN COVALENT AND NONCOVALENT COMPLEXES WITH DNA, Science, 279(5356), 1998, pp. 1504-1513
Authors:
MINKE W
HOVEY B
SARFATY S
HOU Z
ZHANG ZS
ROACH C
LASSILA K
HOF S
HINDSGAUL O
HOLMES RK
FAN E
MERRITT E
VERLINDE C
HOL WGJ
Citation: W. Minke et al., CRYSTAL-STRUCTURES OF CHOLERA-TOXIN AND ESCHERICHIA-COLI HEAT-LABILE ENTEROTOXIN AND STRUCTURE-BASED DESIGN OF TOXIN ANTAGONISTS, Naunyn-Schmiedeberg's archives of pharmacology, 358(1), 1998, pp. 35-35
Authors:
VERLINDE C
BERNSTEIN B
KIM HD
CHUDZIK D
BACA A
WOODEN J
LI RB
CHOE JW
BRESSI J
GELB M
BLACKBURN M
FAN E
HOL WGJ
Citation: C. Verlinde et al., STRUCTURE-BASED DESIGN OF INHIBITORS OF KEY PROTEINS IN TRYPANOSOMA-BRUCEI AND PLASMODIUM-FALCIPARUM, Naunyn-Schmiedeberg's archives of pharmacology, 358(1), 1998, pp. 105-105
Citation: G. Rudenko et al., THE ATOMIC MODEL OF THE HUMAN PROTECTIVE PROTEIN CATHEPSIN-A SUGGESTSA STRUCTURAL BASIS FOR GALACTOSIALIDOSIS, Proceedings of the National Academy of Sciences of the United Statesof America, 95(2), 1998, pp. 621-625
Authors:
BERNSTEIN BE
WILLIAMS DM
BRESSI JC
KUHN P
GELB MH
BLACKBURN GM
HOL WGJ
Citation: Be. Bernstein et al., A BISUBSTRATE ANALOG INDUCES UNEXPECTED CONFORMATIONAL-CHANGES IN PHOSPHOGLYCERATE KINASE FROM TRYPANOSOMA-BRUCEI, Journal of Molecular Biology, 279(5), 1998, pp. 1137-1148
Citation: H. Kim et Wgj. Hol, CRYSTAL-STRUCTURE OF LEISHMANIA-MEXICANA GLYCOSOMAL GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE IN A NEW CRYSTAL FORM CONFIRMS THE PUTATIVE PHYSIOLOGICAL ACTIVE-SITE STRUCTURE, Journal of Molecular Biology, 278(1), 1998, pp. 5-11
Citation: Am. Aronov et al., SELECTIVE TIGHT-BINDING INHIBITORS OF TRYPANOSOMAL GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE VIA STRUCTURE-BASED DRUG DESIGN, Journal of medicinal chemistry, 41(24), 1998, pp. 4790-4799
Citation: E. Pohl et al., MOTION OF THE DNA-BINDING DOMAIN WITH RESPECT TO THE CORE OF THE DIPHTHERIA-TOXIN REPRESSOR (DTXR) REVEALED IN THE CRYSTAL-STRUCTURES OF APO-DTXR AND HOLO-DTXR, The Journal of biological chemistry, 273(35), 1998, pp. 22420-22427
Authors:
DEHAAN L
VERWEIJ WR
FEIL IK
HOLTROP M
HOL WGJ
AGSTERIBBE E
WILSCHUT J
Citation: L. Dehaan et al., ROLE OF G(M1) BINDING IN THE MUCOSAL IMMUNOGENICITY AND ADJUVANT ACTIVITY OF THE ESCHERICHIA-COLI HEAT-LABILE ENTEROTOXIN AND ITS B-SUBUNIT, Immunology, 94(3), 1998, pp. 424-430
Authors:
DEHAAN L
FEIL IK
VERWEIJ WR
HOLTROP M
HOL WGJ
AGSTERIBBE E
WILSCHUT J
Citation: L. Dehaan et al., MUTATIONAL ANALYSIS OF THE ROLE OF ADP-RIBOSYLATION ACTIVITY AND G(M1)-BINDING ACTIVITY IN THE ADJUVANT PROPERTIES OF THE ESCHERICHIA-COLI HEAT-LABILE ENTEROTOXIN TOWARDS INTRANASALLY ADMINISTERED KEYHOLE LIMPET HEMOCYANIN, European Journal of Immunology, 28(4), 1998, pp. 1243-1250
Citation: H. Kim et al., CRYSTAL-STRUCTURE OF FRUCTOSE-1,6-BISPHOSPHATE ALDOLASE FROM THE HUMAN MALARIA PARASITE PLASMODIUM-FALCIPARUM, Biochemistry, 37(13), 1998, pp. 4388-4396
Citation: Be. Bernstein et Wgj. Hol, CRYSTAL-STRUCTURES OF SUBSTRATES AND PRODUCTS BOUND TO THE PHOSPHOGLYCERATE KINASE ACTIVE-SITE REVEAL THE CATALYTIC MECHANISM, Biochemistry, 37(13), 1998, pp. 4429-4436
Citation: Ea. Merritt et al., STRUCTURAL FOUNDATION FOR THE DESIGN OF RECEPTOR ANTAGONISTS TARGETING ESCHERICHIA-COLI HEAT-LABILE ENTEROTOXIN, Structure, 5(11), 1997, pp. 1485-1499
Citation: E. Pohl et al., COMPARISON OF HIGH-RESOLUTION STRUCTURES OF THE DIPHTHERIA-TOXIN REPRESSOR IN COMPLEX WITH COBALT AND ZINC AT THE CATION-ANION BINDING-SITE, Protein science, 6(5), 1997, pp. 1114-1118
Authors:
IZARD T
SARFATY S
WESTPHAL A
DEKOK A
HOL WGJ
Citation: T. Izard et al., IMPROVEMENT OF DIFFRACTION QUALITY UPON REHYDRATION OF DEHYDRATED ICOSAHEDRAL ENTEROCOCCUS-FAECALIS PYRUVATE-DEHYDROGENASE CORE CRYSTALS, Protein science, 6(4), 1997, pp. 913-915
Authors:
VANDENAKKER F
FEIL IK
ROACH C
PLATAS AA
MERRITT EA
HOL WGJ
Citation: F. Vandenakker et al., CRYSTAL-STRUCTURE OF HEAT-LABILE ENTEROTOXIN FROM ESCHERICHIA-COLI WITH INCREASED THERMOSTABILITY INTRODUCED BY AN ENGINEERED DISULFIDE BOND IN THE A-SUBUNIT, Protein science, 6(12), 1997, pp. 2644-2649
Citation: F. Vandenakker et al., CRYSTAL-STRUCTURE OF A NONTOXIC MUTANT OF HEAT-LABILE ENTEROTOXIN, WHICH IS A POTENT MUCOSAL ADJUVANT, Protein science, 6(12), 1997, pp. 2650-2654
Citation: Be. Bernstein et Wgj. Hol, PROBING THE LIMITS OF THE MOLECULAR REPLACEMENT METHOD - THE CASE OF TRYPANOSOMA-BRUCEI PHOSPHOGLYCERATE KINASE, Acta crystallographica. Section D, Biological crystallography, 53, 1997, pp. 756-764