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Results: 1-25/33
Authors:
PRICE RJ
RENWICK AB
BARTON PT
HOUSTON JB
LAKE BG
Citation: Rj. Price et al., INFLUENCE OF SLICE THICKNESS AND CULTURE CONDITIONS ON THE METABOLISMOF 7-ETHOXYCOUMARIN IN PRECISION-CUT RAT-LIVER SLICES, ATLA. Alternatives to laboratory animals, 26(4), 1998, pp. 541-548
Authors:
WORTH AP
BARRATT MD
HOUSTON JB
Citation: Ap. Worth et al., THE VALIDATION OF COMPUTATIONAL PREDICTION TECHNIQUES, ATLA. Alternatives to laboratory animals, 26(2), 1998, pp. 241-247
Authors:
CARLILE DJ
STEVENS AJ
ASHFORTH EIL
WAGHELA D
HOUSTON JB
Citation: Dj. Carlile et al., IN-VIVO CLEARANCE OF ETHOXYCOUMARIN AND ITS PREDICTION FROM IN-VITRO SYSTEMS - USE OF DRUG DEPLETION AND METABOLITE FORMATION METHODS IN HEPATIC MICROSOMES AND ISOLATED HEPATOCYTES, Drug metabolism and disposition, 26(3), 1998, pp. 216-221
Authors:
HOUSTON JB
CARLILE DJ
Citation: Jb. Houston et Dj. Carlile, INCORPORATION OF IN-VITRO DRUG-METABOLISM DATA INTO PHYSIOLOGICALLY-BASED PHARMACOKINETIC MODELS, Toxicology in vitro, 11(5), 1997, pp. 473-478
Authors:
HOUSTON JB
CARLILE DJ
Citation: Jb. Houston et Dj. Carlile, PREDICTION OF HEPATIC-CLEARANCE FROM MICROSOMES, HEPATOCYTES, AND LIVER SLICES, Drug metabolism reviews, 29(4), 1997, pp. 891-922
Authors:
LEAHY DE
DUNCAN R
AHR HJ
BAYLISS MK
DEBOER AG
DARVAS F
FENTEM JH
FRY JR
HOPKINS R
HOUSTON JB
KARLSSON J
KEDDERIS GL
PRATTEN MK
PRIETO P
SMITH DA
STRAUGHAN DW
Citation: De. Leahy et al., PHARMACOKINETICS IN EARLY DRUG RESEARCH - THE REPORT AND RECOMMENDATIONS OF ECVAM WORKSHOP-22, ATLA. Alternatives to laboratory animals, 25(1), 1997, pp. 17-31
Authors:
CARLILE DJ
ZOMORODI K
HOUSTON JB
Citation: Dj. Carlile et al., SCALING FACTORS TO RELATE DRUG METABOLIC-CLEARANCE IN HEPATIC MICROSOMES, ISOLATED HEPATOCYTES, AND THE INTACT LIVER - STUDIES WITH INDUCEDLIVERS INVOLVING DIAZEPAM, Drug metabolism and disposition, 25(8), 1997, pp. 903-911
Authors:
WORBOYS PD
BRADBURY A
HOUSTON JB
Citation: Pd. Worboys et al., KINETICS OF DRUG-METABOLISM IN RAT-LIVER SLICES .3. RELATIONSHIP BETWEEN METABOLIC-CLEARANCE AND SLICE UPTAKE RATE, Drug metabolism and disposition, 25(4), 1997, pp. 460-467
Authors:
ZOMORODI K
HOUSTON JB
Citation: K. Zomorodi et Jb. Houston, SELECTIVITY OF OMEPRAZOLE INHIBITION TOWARDS RAT-LIVER CYTOCHROMES P450, Xenobiotica, 27(1), 1997, pp. 49-58
Authors:
ZOMORODI K
HOUSTON JB
Citation: K. Zomorodi et Jb. Houston, DIAZEPAM-OMEPRAZOLE INHIBITION INTERACTION - AN IN-VITRO INVESTIGATION USING HUMAN LIVER-MICROSOMES, British journal of clinical pharmacology, 42(2), 1996, pp. 157-162
Authors:
BLAAUBOER BJ
BAYLISS MK
CASTELL JV
EVELO CTA
FRAZIER JM
GROEN K
GULDEN M
GUILLOUZO A
HISSINK AM
HOUSTON JB
JOHANSON G
DEJONGH J
KEDDERIS GL
REINHARDT CA
VANDESANDT JJM
SEMINO G
Citation: Bj. Blaauboer et al., THE USE OF BIOKINETICS AND IN-VITRO METHODS IN TOXICOLOGICAL RISK-EVALUATION - THE REPORT AND RECOMMENDATIONS OF ECVAM WORKSHOP 15, ATLA. Alternatives to laboratory animals, 24(4), 1996, pp. 473-497
Authors:
WORBOYS PD
BRADBURY A
HOUSTON JB
Citation: Pd. Worboys et al., KINETICS OF DRUG-METABOLISM IN RAT-LIVER SLICES .2. COMPARISON OF CLEARANCE BY LIVER SLICES AND FRESHLY ISOLATED HEPATOCYTES, Drug metabolism and disposition, 24(6), 1996, pp. 676-681
Authors:
ERVINE CM
MATTHEW DE
BRENNAN B
HOUSTON JB
Citation: Cm. Ervine et al., COMPARISON OF KETOCONAZOLE AND FLUCONAZOLE AS CYTOCHROME-P450 INHIBITORS - USE OF STEADY-STATE INFUSION APPROACH TO ACHIEVE PLASMA CONCENTRATION-RESPONSE RELATIONSHIPS, Drug metabolism and disposition, 24(2), 1996, pp. 211-215
Authors:
WORBOYS PD
BRENNAN B
BRADBURY A
HOUSTON JB
Citation: Pd. Worboys et al., METABOLITE KINETICS OF ONDANSETRON IN RAT - COMPARISON OF HEPATIC MICROSOMES, ISOLATED HEPATOCYTES AND LIVER SLICES, WITH IN-VIVO DISPOSITION, Xenobiotica, 26(9), 1996, pp. 897-907
Authors:
FORD J
MARTIN SW
HOUSTON JB
Citation: J. Ford et al., ASSESSMENT OF INTESTINAL PERMEABILITY CHANGES INDUCED BY NONSTEROIDALANTIINFLAMMATORY DRUGS IN THE RAT, Journal of pharmacological and toxicological methods, 34(1), 1995, pp. 9-16
Authors:
FORD J
HOUSTON JB
Citation: J. Ford et Jb. Houston, CONCENTRATION-RESPONSE RELATIONSHIPS FOR 3 NONSTEROIDAL ANTIINFLAMMATORY DRUGS IN THE RAT INTESTINE, Human & experimental toxicology, 14(7), 1995, pp. 573-579
Authors:
DAVIS JD
AARONS L
HOUSTON JB
Citation: Jd. Davis et al., EFFECT OF NORFLOXACIN ON THEOPHYLLINE DISPOSITION - A COMPARISON WITHOTHER FLUOROQUINOLONES, Pharmaceutical research, 12(2), 1995, pp. 257-262
Authors:
MARTIN SW
STEVENS AJ
BRENNAN BS
REIS ML
GIFFORD LA
ROWLAND M
HOUSTON JB
Citation: Sw. Martin et al., REGIONAL DRUG-DELIVERY .1. PERMEABILITY CHARACTERISTICS OF THE RAT 6-DAY-OLD AIR POUCH MODEL OF INFLAMMATION, Pharmaceutical research, 12(12), 1995, pp. 1980-1986
Authors:
ZOMORODI K
HOUSTON JB
Citation: K. Zomorodi et Jb. Houston, EFFECT OF OMEPRAZOLE ON DIAZEPAM DISPOSITION IN THE RAT - IN-VITRO AND IN-VIVO STUDIES, Pharmaceutical research, 12(11), 1995, pp. 1642-1646
Authors:
HAYES KA
BRENNAN B
CHENERY R
HOUSTON JB
Citation: Ka. Hayes et al., IN-VIVO DISPOSITION OF CAFFEINE PREDICTED FROM HEPATIC-MICROSOMAL ANDHEPATOCYTE DATA, Drug metabolism and disposition, 23(3), 1995, pp. 349-353
Authors:
WORBOYS PD
BRADBURY A
HOUSTON JB
Citation: Pd. Worboys et al., KINETICS OF DRUG-METABOLISM IN RAT-LIVER SLICES - RATES OF OXIDATION OF ETHOXYCOUMARIN AND TOLBUTAMIDE, EXAMPLES OF HIGH-CLEARANCE AND LOW-CLEARANCE COMPOUNDS, Drug metabolism and disposition, 23(3), 1995, pp. 393-397
Authors:
ZOMORODI K
CARLILE DJ
HOUSTON JB
Citation: K. Zomorodi et al., KINETICS OF DIAZEPAM METABOLISM IN RAT HEPATIC MICROSOMES AND HEPATOCYTES AND THEIR USE IN PREDICTING IN-VIVO HEPATIC-CLEARANCE, Xenobiotica, 25(9), 1995, pp. 907-916
Authors:
DAVIS JD
AARONS L
HOUSTON JB
Citation: Jd. Davis et al., METABOLISM OF THEOPHYLLINE AND ITS INHIBITION BY FLUOROQUINOLONES IN RAT HEPATIC MICROSOMES, Xenobiotica, 25(6), 1995, pp. 563-573
Authors:
MARTIN SW
STEVENS AJ
BRENNAN BS
ROWLAND M
HOUSTON JB
Citation: Sw. Martin et al., PHARMACODYNAMIC COMPARISON OF REGIONAL DRUG-DELIVERY FOR NONSTEROIDALANTIINFLAMMATORY DRUGS, USING THE RAT AIR-POUCH MODEL OF INFLAMMATION, Journal of Pharmacy and Pharmacology, 47(6), 1995, pp. 458-461
Authors:
ASHFORTH EIL
CARLILE DJ
CHENERY R
HOUSTON JB
Citation: Eil. Ashforth et al., PREDICTION OF IN-VIVO DISPOSITION FROM IN-VITRO SYSTEMS - CLEARANCE OF PHENYTOIN AND TOLBUTAMIDE USING RAT HEPATIC-MICROSOMAL AND HEPATOCYTE DATA, The Journal of pharmacology and experimental therapeutics, 274(2), 1995, pp. 761-766