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Results:
1-11
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Results: 11
Authors:
DIONSCHULTZ A
HOWELL EE
Citation: A. Dionschultz et Ee. Howell, EFFECTS OF INSERTIONS AND DELETIONS IN A BETA-BULGE REGION OF ESCHERICHIA-COLI DIHYDROFOLATE-REDUCTASE, Protein engineering, 10(3), 1997, pp. 263-272
Authors:
PARK H
BRADRICK TD
HOWELL EE
Citation: H. Park et al., A GLUTAMINE 67-]HISTIDINE MUTATION IN HOMOTETRAMERIC R67 DIHYDROFOLATE-REDUCTASE RESULTS IN 4 MUTATIONS PER SINGLE ACTIVE-SITE PORE AND CAUSES SUBSTANTIAL SUBSTRATE AND COFACTOR INHIBITION, Protein engineering, 10(12), 1997, pp. 1415-1424
Authors:
PARK HY
ZHUANG P
NICHOLS R
HOWELL EE
Citation: Hy. Park et al., MECHANISTIC STUDIES OF R67 DIHYDROFOLATE-REDUCTASE - EFFECTS OF PH AND AN H62C MUTATION, The Journal of biological chemistry, 272(4), 1997, pp. 2252-2258
Authors:
YANG QX
HUANG FY
LIN TH
GELBAUM L
HOWELL EE
HUANG TH
Citation: Qx. Yang et al., DYNAMICS OF TRIMETHOPRIM BOUND TO DIHYDROFOLATE-REDUCTASE - A DEUTERIUM NMR-STUDY, Solid state nuclear magnetic resonance, 7(3), 1996, pp. 193-201
Authors:
BRADRICK TD
SHATTUCK C
STRADER MB
WICKER C
EISENSTEIN E
HOWELL EE
Citation: Td. Bradrick et al., REDESIGNING THE QUATERNARY STRUCTURE OF R67 DIHYDROFOLATE-REDUCTASE -CREATION OF AN ACTIVE MONOMER FROM A TETRAMERIC PROTEIN BY QUADRUPLICATION OF THE GENE, The Journal of biological chemistry, 271(45), 1996, pp. 28031-28037
Authors:
BRADRICK TD
BEECHEM JM
HOWELL EE
Citation: Td. Bradrick et al., UNUSUAL BINDING STOICHIOMETRIES AND COOPERATIVITY ARE OBSERVED DURINGBINARY AND TERNARY COMPLEX-FORMATION IN THE SINGLE ACTIVE PORE OF R67DIHYDROFOLATE-REDUCTASE, A D-2 SYMMETRICAL PROTEIN, Biochemistry, 35(35), 1996, pp. 11414-11424
Authors:
NARAYANA N
MATTHEWS DA
HOWELL EE
XUONG NH
Citation: N. Narayana et al., A PLASMID-ENCODED DIHYDROFOLATE-REDUCTASE FROM TRIMETHOPRIM-RESISTANTBACTERIA HAS A NOVEL D-2-SYMMETRICAL ACTIVE-SITE, Nature structural biology, 2(11), 1995, pp. 1018-1025
Authors:
HOWELL EE
SHATTUCK C
Citation: Ee. Howell et C. Shattuck, CONSTRUCTION OF AN ACTIVE, MONOMERIC R67 DIHYDROFOLATE-REDUCTASE BY GENE QUADRUPLICATION, The FASEB journal, 9(6), 1995, pp. 1483-1483
Authors:
ZHUANG P
EISENSTEIN E
HOWELL EE
Citation: P. Zhuang et al., EQUILIBRIUM FOLDING STUDIES OF TETRAMERIC R67 DIHYDROFOLATE-REDUCTASE, Biochemistry, 33(14), 1994, pp. 4237-4244
Authors:
BROWN KA
HOWELL EE
KRAUT J
Citation: Ka. Brown et al., LONG-RANGE STRUCTURAL EFFECTS IN A 2ND-SITE REVERTANT OF A MUTANT DIHYDROFOLATE-REDUCTASE, Proceedings of the National Academy of Sciences of the United Statesof America, 90(24), 1993, pp. 11753-11756
Authors:
ZHUANG P
YIN M
HOLLAND JC
PETERSON CB
HOWELL EE
Citation: P. Zhuang et al., ARTIFICIAL DUPLICATION OF THE R67 DIHYDROFOLATE-REDUCTASE GENE TO CREATE PROTEIN ASYMMETRY - EFFECTS ON PROTEIN-ACTIVITY AND FOLDING, The Journal of biological chemistry, 268(30), 1993, pp. 22672-22679
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