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Results: 1-9 |
Results: 9
STRUCTURES OF TYR188LEU MUTANT AND WILD-TYPE HIV-1 REVERSE-TRANSCRIPTASE COMPLEXED WITH THE NONNUCLEOSIDE INHIBITOR HBY-097 - INHIBITOR FLEXIBILITY IS A USEFUL DESIGN FEATURE FOR REDUCING DRUG-RESISTANCE
Authors: HSIOU Y DAS KY DING JP CLARK AD KLEIM JP ROSNER M WINKLER I RIESS G HUGHES SH ARNOLD E
Citation: Y. Hsiou et al., STRUCTURES OF TYR188LEU MUTANT AND WILD-TYPE HIV-1 REVERSE-TRANSCRIPTASE COMPLEXED WITH THE NONNUCLEOSIDE INHIBITOR HBY-097 - INHIBITOR FLEXIBILITY IS A USEFUL DESIGN FEATURE FOR REDUCING DRUG-RESISTANCE, Journal of Molecular Biology, 284(2), 1998, pp. 313-323
STRUCTURE OF UNLIGANDED HIV-1 REVERSE-TRANSCRIPTASE AT 2.7 ANGSTROM RESOLUTION - IMPLICATIONS OF CONFORMATIONAL-CHANGES FOR POLYMERIZATION AND INHIBITION MECHANISMS
Authors: HSIOU Y DING J DAS K CLARK AD HUGHES SH ARNOLD E
Citation: Y. Hsiou et al., STRUCTURE OF UNLIGANDED HIV-1 REVERSE-TRANSCRIPTASE AT 2.7 ANGSTROM RESOLUTION - IMPLICATIONS OF CONFORMATIONAL-CHANGES FOR POLYMERIZATION AND INHIBITION MECHANISMS, Structure, 4(7), 1996, pp. 853-860
SELECTIVE PRESSURE OF A QUINOXALINE NONNUCLEOSIDE INHIBITOR OF HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 (HIV-1) REVERSE-TRANSCRIPTASE (RT) ON HIV-1 REPLICATION RESULTS IN THE EMERGENCE OF NUCLEOSIDE RT-INHIBITOR-SPECIFIC (RT LEU-74-]VAL OR ILE AND VAL-75-]LEU OR ILE) HIV-1 MUTANTS
Authors: KLEIM JP ROSNER M WINKLER I PAESSENS A KIRSCH R HSIOU Y ARNOLD E RIESS G
Citation: Jp. Kleim et al., SELECTIVE PRESSURE OF A QUINOXALINE NONNUCLEOSIDE INHIBITOR OF HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 (HIV-1) REVERSE-TRANSCRIPTASE (RT) ON HIV-1 REPLICATION RESULTS IN THE EMERGENCE OF NUCLEOSIDE RT-INHIBITOR-SPECIFIC (RT LEU-74-]VAL OR ILE AND VAL-75-]LEU OR ILE) HIV-1 MUTANTS, Proceedings of the National Academy of Sciences of the United Statesof America, 93(1), 1996, pp. 34-38
CRYSTAL-STRUCTURES OF 8-CL AND 9-CL TIBO COMPLEXED WITH WILD-TYPE HIV-1 RT AND 8-CL TIBO COMPLEXED WITH THE TYR181CYS HIV-1 RT DRUG-RESISTANT MUTANT
Authors: DAS K DING JP HSIOU Y CLARK AD MOEREELS H KOYMANS L ANDRIES K PAUWELS R JANSSEN PAJ BOYER PL CLARK P SMITH RH SMITH MBK MICHEJDA CJ HUGHES SH ARNOLD E
Citation: K. Das et al., CRYSTAL-STRUCTURES OF 8-CL AND 9-CL TIBO COMPLEXED WITH WILD-TYPE HIV-1 RT AND 8-CL TIBO COMPLEXED WITH THE TYR181CYS HIV-1 RT DRUG-RESISTANT MUTANT, Journal of Molecular Biology, 264(5), 1996, pp. 1085-1100
NUCLEOSIDE REVERSE-TRANSCRIPTASE (RT) INHIBITOR-SPECIFIC MUTATIONS WITHIN THE HIV-1 POL GENE SELECTED WITH A NONNUCLEOSIDE TYPE RT INHIBITOR
Authors: KLEIM JP ROSNER M WINKLER I PAESSENS A KIRSCH R HSIOU Y ARNOLD E RIESS G
Citation: Jp. Kleim et al., NUCLEOSIDE REVERSE-TRANSCRIPTASE (RT) INHIBITOR-SPECIFIC MUTATIONS WITHIN THE HIV-1 POL GENE SELECTED WITH A NONNUCLEOSIDE TYPE RT INHIBITOR, Journal of acquired immune deficiency syndromes and human retrovirology, 10, 1995, pp. 3-3
THE ROLE OF NUCLEIC-ACID IN THE RESISTANCE OF HIV-1 REVERSE-TRANSCRIPTASE TO NUCLEOSIDE AND NONNUCLEOSIDE INHIBITORS
Authors: ARNOLD E DAS K DING JP HSIOU Y TANTILLO C ROY BM YADAV P ZHANG WY LENTZ K CLARK AD BOYER PL HUGHES SH MITSUYA H MELLORS J KLEIM JP ROSNER M MOEREELS HR KOYMANS L ANDRIES K PAUWELS R JANSSEN PAJ
Citation: E. Arnold et al., THE ROLE OF NUCLEIC-ACID IN THE RESISTANCE OF HIV-1 REVERSE-TRANSCRIPTASE TO NUCLEOSIDE AND NONNUCLEOSIDE INHIBITORS, Journal of acquired immune deficiency syndromes and human retrovirology, 10, 1995, pp. 7-7
STRUCTURE OF HIV-1 REVERSE-TRANSCRIPTASE IN A COMPLEX WITH THE NONNUCLEOSIDE INHIBITOR ALPHA-APA-R-95845 AT 2.8-ANGSTROM RESOLUTION
Authors: DING J DAS K TANTILLO C ZHANG W CLARK AD JESSEN S LU X HSIOU Y JACOBOMOLINA A ANDRIES K PAUWELS R MOEREELS H KOYMANS L JANSSEN PAJ SMITH RH KOEPKE MK MICHEJDA CJ HUGHES SH ARNOLD E
Citation: J. Ding et al., STRUCTURE OF HIV-1 REVERSE-TRANSCRIPTASE IN A COMPLEX WITH THE NONNUCLEOSIDE INHIBITOR ALPHA-APA-R-95845 AT 2.8-ANGSTROM RESOLUTION, Structure, 3(4), 1995, pp. 365-379
NOVEL MUTATIONS IN REVERSE-TRANSCRIPTASE OF HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 REDUCE SUSCEPTIBILITY TO FOSCARNET IN LABORATORY AND CLINICAL ISOLATES
Authors: MELLORS JW BAZMI HZ SCHINAZI RF ROY BM HSIOU Y ARNOLD E WEIR J MAYERS DL
Citation: Jw. Mellors et al., NOVEL MUTATIONS IN REVERSE-TRANSCRIPTASE OF HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 REDUCE SUSCEPTIBILITY TO FOSCARNET IN LABORATORY AND CLINICAL ISOLATES, Antimicrobial agents and chemotherapy, 39(5), 1995, pp. 1087-1092
PORPHYRIN SPONGES - CONSERVATION OF HOST STRUCTURE IN OVER 200 PORPHYRIN-BASED LATTICE CLATHRATES
Authors: BYRN MP CURTIS CJ HSIOU Y KHAN SI SAWIN PA TENDICK SK TERZIS A STROUSE CE
Citation: Mp. Byrn et al., PORPHYRIN SPONGES - CONSERVATION OF HOST STRUCTURE IN OVER 200 PORPHYRIN-BASED LATTICE CLATHRATES, Journal of the American Chemical Society, 115(21), 1993, pp. 9480-9497
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