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Results: 1-25/53
Authors:
Sastre, M
Steiner, H
Fuchs, K
Capell, A
Multhaup, G
Condron, MM
Teplow, DB
Haass, C
Citation: M. Sastre et al., Presenilin dependent gamma-secretase processing of beta-amyloid precursor protein at a site corresponding to the S3 cleavage of Notch, EMBO REP, 2(9), 2001, pp. 835-841
Authors:
Haass, C
Steiner, H
Citation: C. Haass et H. Steiner, Protofibrils, the unifying toxic molecule of neurodegenerative disorders?, NAT NEUROSC, 4(9), 2001, pp. 859-860
Authors:
Steiner, H
Winkler, E
Shearman, MS
Prywes, R
Haass, C
Citation: H. Steiner et al., Endoproteolysis of the ER stress transducer ATF6 in the presence of functionally inactive presenilins, NEUROBIOL D, 8(4), 2001, pp. 717-722
Authors:
Walter, J
Kaether, C
Steiner, H
Haass, C
Citation: J. Walter et al., The cell biology of Alzheimer's disease: uncovering the secrets of secretases, CUR OP NEUR, 11(5), 2001, pp. 585-590
Authors:
Steiner, H
Haass, C
Citation: H. Steiner et C. Haass, Nuclear signaling - A common function of presenilin substrates?, J MOL NEURO, 17(2), 2001, pp. 193-198
Authors:
Eckert, A
Steiner, B
Marques, C
Leutz, S
Romig, H
Haass, C
Muller, WE
Citation: A. Eckert et al., Elevated vulnerability to oxidative stress-induced cell death and activation of caspase-3 by the Swedish amyloid precursor protein mutation, J NEUROSC R, 64(2), 2001, pp. 183-192
Authors:
Haass, C
Kahle, PJ
Citation: C. Haass et Pj. Kahle, Neuroscience - Parkin and its substrates, SCIENCE, 293(5528), 2001, pp. 224-225
Authors:
Rathke-Hartlieb, S
Kahle, PJ
Neumann, M
Ozmen, L
Haid, S
Okochi, M
Haass, C
Schulz, JB
Citation: S. Rathke-hartlieb et al., Sensitivity to MPTP is not increased in Parkinson's disease-associated mutant alpha-synuclein transgenic mice, J NEUROCHEM, 77(4), 2001, pp. 1181-1184
Authors:
Wolfe, MS
Haass, C
Citation: Ms. Wolfe et C. Haass, The role of presenilins in gamma-secretase activity, J BIOL CHEM, 276(8), 2001, pp. 5413-5416
Authors:
Yamazaki, T
Chang, TY
Haass, C
Ihara, Y
Citation: T. Yamazaki et al., Accumulation and aggregation of amyloid beta-protein in late endosomes of Niemann-Pick type C cells, J BIOL CHEM, 276(6), 2001, pp. 4454-4460
Authors:
Walter, J
Fluhrer, R
Hartung, B
Willem, M
Kaether, C
Capell, A
Lammich, S
Multhaup, G
Haass, C
Citation: J. Walter et al., Phosphorylation regulates intracellular trafficking of beta-secretase, J BIOL CHEM, 276(18), 2001, pp. 14634-14641
Authors:
Steiner, H
Revesz, T
Neumann, M
Romig, H
Grim, MG
Pesold, B
Kretzschmar, HA
Hardy, J
Holton, JL
Baumeister, R
Houlden, H
Haass, C
Citation: H. Steiner et al., A pathogenic presenilin-1 deletion causes abberrant A beta 42 production in the absence of congophilic amyloid plaques, J BIOL CHEM, 276(10), 2001, pp. 7233-7239
Authors:
Kahle, PJ
Neumann, M
Ozmen, L
Muller, V
Odoy, S
Okamoto, N
Jacobsen, H
Iwatsubo, T
Trojanowski, JQ
Takahashi, H
Wakabayashi, K
Bogdanovic, N
Riederer, P
Kretzschmar, HA
Haass, C
Citation: Pj. Kahle et al., Selective insolubility of alpha-Synuclein in human Lewy body diseases is recapitulated in a transgenic mouse model, AM J PATH, 159(6), 2001, pp. 2215-2225
Authors:
Steiner, H
Haass, C
Citation: H. Steiner et C. Haass, A novel protease active site motif conserved in presenilins and polytopic bacterial aspartyl proteases?, ALZHEIMER'S DISEASE, 2001, pp. 549-558
Authors:
Kahle, PJ
Neumann, M
Ozmen, L
Kretzschmar, HA
Haass, C
Citation: Pj. Kahle et al., Somal and neuritic accumulation of the Parkinson's disease-associated mutant [A30P] alpha-synuclein in transgenic mice, ALZHEIMER'S DISEASE, 2001, pp. 671-677
Authors:
Steiner, H
Haass, C
Citation: H. Steiner et C. Haass, Intramembrane proteolysis by presenilins, NAT REV MOL, 1(3), 2000, pp. 217-224
Authors:
Capell, A
Steiner, H
Romig, H
Keck, S
Baader, M
Grim, MG
Baumeister, R
Haass, C
Citation: A. Capell et al., Presenilin-1 differentially facilitates endoproteolysis of the beta-amyloid precursor protein and Notch, NAT CELL BI, 2(4), 2000, pp. 205-211
Authors:
Steiner, H
Kostka, M
Romig, H
Basset, G
Pesold, B
Hardy, J
Capell, A
Meyn, L
Grim, ML
Baumeister, R
Fechteler, K
Haass, C
Citation: H. Steiner et al., Glycine 384 is required for presenilin-1 function and is conserved in bacterial polytopic aspartyl proteases, NAT CELL BI, 2(11), 2000, pp. 848-851
Authors:
Hayashi, H
Mizuno, T
Michikawa, M
Haass, C
Yanagisawa, K
Citation: H. Hayashi et al., Amyloid precursor protein in unique cholesterol-rich microdomains different from caveolae-like domains, BBA-MOL C B, 1483(1), 2000, pp. 81-90
Authors:
Mathews, PM
Cataldo, AM
Kao, BH
Rudnicki, AG
Qin, X
Yang, JL
Jiang, Y
Picciano, M
Hulette, C
Lippa, CF
Bird, TD
Nochlin, D
Walter, J
Haass, C
Levesque, L
Fraser, PE
Andreadis, A
Nixon, RA
Citation: Pm. Mathews et al., Brain expression of presenilins in sporadic and early-onset, familial Alzheimer's disease, MOL MED, 6(10), 2000, pp. 878-891
Authors:
Kahle, PJ
Leimer, U
Haass, C
Citation: Pj. Kahle et al., Does failure of parkin-mediated ubiquitination cause juvenile parkinsonism?, TRENDS BIOC, 25(11), 2000, pp. 524-527
Authors:
Wirths, O
Weickert, S
Majtenyi, K
Havas, L
Kahle, PJ
Okochi, M
Haass, C
Multhaup, G
Beyreuther, K
Bayer, TA
Citation: O. Wirths et al., Lewy body variant of Alzheimer's disease: alpha-synuclein in dystrophic neurites of A beta plaques, NEUROREPORT, 11(17), 2000, pp. 3737-3741
Authors:
Kahle, PJ
Neumann, M
Ozmen, L
Muller, V
Jacobsen, H
Schindzielorz, A
Okochi, M
Leimer, U
van der Putten, H
Probst, A
Kremmer, E
Kretzschmar, HA
Haass, C
Citation: Pj. Kahle et al., Subcellular localization of wild-type and Parkinson's disease-associated mutant alpha-synuclein in human and transgenic mouse brain, J NEUROSC, 20(17), 2000, pp. 6365-6373
Authors:
Haass, C
Kahle, PJ
Citation: C. Haass et Pj. Kahle, Neurodegenerative diseases - Parkinson's pathology in a fly, NATURE, 404(6776), 2000, pp. 341
Authors:
Kulic, L
Walter, J
Multhaup, G
Teplow, DB
Baumeister, R
Romig, H
Capell, A
Steiner, H
Haass, C
Citation: L. Kulic et al., Separation of presenilin function in amyloid beta-peptide generation and endoproteolysis of Notch, P NAS US, 97(11), 2000, pp. 5913-5918