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Results:
1-24
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Results: 24
Authors:
Reichert, W
Hartmann, RW
Jose, J
Citation: W. Reichert et al., Stable expression of the human 5 alpha-reductase isoenzymes type I and type II in HEK293 cells to identify dual and selective inhibitors, J ENZ INHIB, 16(1), 2001, pp. 47-53
Authors:
Reichert, W
Michel, A
Hartmann, RW
Jose, J
Citation: W. Reichert et al., Stable expression of human 5 alpha-reductase type II in COS1 cells due to chromosomal gene integration: a novel tool for inhibitor identification, J STEROID B, 78(3), 2001, pp. 275-284
Authors:
Schertl, S
Hartmann, RW
Batzl-Hartmann, C
Schlemmer, R
Spruss, T
Bernhardt, G
Gust, R
Schonenberger, H
Citation: S. Schertl et al., 1-(2,6-dichloro-4-hydroxyphenyl)-2-phenylethanes - New biological responsemodifiers for the therapy of breast cancer. Synthesis and evaluation of estrogenic/antiestrogenic properties, ARCH PHARM, 334(4), 2001, pp. 125-137
Authors:
Haidar, S
Klein, CDP
Hartmann, RW
Citation: S. Haidar et al., Synthesis and evaluation of steroidal hydroxamic acids as inhibitors of P450 17 (17 alpha-hydroxylase/C17-20-lyase), ARCH PHARM, 334(4), 2001, pp. 138-140
Authors:
Kleber, A
Hartmann, RW
Jose, J
Citation: A. Kleber et al., No effect of thromboxane A(2) on the attachment of tumor cell lines MDA MB231, DU145, and U937 to the basement membrane in an in-vitro model, J CANC RES, 127(12), 2001, pp. 751-754
Authors:
Recanatini, M
Bisi, A
Cavalli, A
Belluti, F
Gobbi, S
Rampa, A
Valenti, P
Palzer, M
Palusczak, A
Hartmann, RW
Citation: M. Recanatini et al., A new class of nonsteroidal aromatase inhibitors: Design and synthesis of chromone and xanthone derivatives and inhibition of the P450 enzymes aromatase and 17 alpha-hydroxylase/C17,20-lyase, J MED CHEM, 44(5), 2001, pp. 672-680
Authors:
Hartmann, RW
Tunnessen, WW
Citation: Rw. Hartmann et Ww. Tunnessen, Picture of the month - Congenital aniridia, ARCH PED AD, 154(5), 2000, pp. 525-526
Authors:
Zhuang, Y
Wachall, BG
Hartmann, RW
Citation: Y. Zhuang et al., Novel imidazolyl and triazolyl substituted biphenyl compounds: Synthesis and evaluation as nonsteroidal inhibitors of human 17 alpha-hydroxylase-C17,20-lyase (P450 17), BIO MED CH, 8(6), 2000, pp. 1245-1252
Authors:
Picard, F
Baston, E
Reichert, W
Hartmann, RW
Citation: F. Picard et al., Synthesis of N-substituted piperidine-4-(benzylidene-4-carboxylic acids) and evaluation as inhibitors of steroid-5 alpha-reductase type 1 and 2, BIO MED CH, 8(6), 2000, pp. 1479-1487
Authors:
Ehmer, PB
Jose, J
Hartmann, RW
Citation: Pb. Ehmer et al., Development of a simple and rapid assay for the evaluation of inhibitors of human 17 alpha-hydroxylase-C-17,C-21-lyase (P450c17) by coexpression of P450c17 with NADPH-cytochrome-P450-reductase in Escherichia coli, J STEROID B, 75(1), 2000, pp. 57-63
Authors:
Reichert, W
Jose, J
Hartmann, RW
Citation: W. Reichert et al., 5 alpha-reductase in intact DU145 cells: Evidence for isozyme I and evaluation of novel inhibitors, ARCH PHARM, 333(7), 2000, pp. 201-204
Authors:
Hartmann, RW
Reichert, M
Citation: Rw. Hartmann et M. Reichert, New nonsteroidal steroid 5 alpha-reductase inhibitors. Syntheses and structure-activity studies on carboxamide phenylalkyl-substituted pyridones and piperidones, ARCH PHARM, 333(5), 2000, pp. 145-153
Authors:
Baston, E
Palusczak, A
Hartmann, RW
Citation: E. Baston et al., 6-substituted 1H-quinolin-2-ones and 2-methoxy-quinolines: Synthesis and evaluation as inhibitors of steroid 5 alpha reductases types 1 and 2, EUR J MED C, 35(10), 2000, pp. 931-940
Authors:
Jacobs, C
Frotscher, M
Dannhardt, G
Hartmann, RW
Citation: C. Jacobs et al., 1-imidazolyl(alkyl)-substituted di- and tetrahydroquinolines and analogues: Syntheses and evaluation of dual inhibitors of thromboxane A(2) synthase and aromatase, J MED CHEM, 43(9), 2000, pp. 1841-1851
Authors:
Hartmann, RW
Hector, M
Wachall, BG
Palusczak, A
Palzer, M
Huch, V
Veith, M
Citation: Rw. Hartmann et al., Synthesis and evaluation of 17-aliphatic heterocycle-substituted steroidalinhibitors of 17 alpha-hydroxylase/C17-20-lyase (P450 17), J MED CHEM, 43(23), 2000, pp. 4437-4445
Authors:
Hartmann, RW
Hector, M
Haidar, S
Ehmer, PB
Reichert, W
Jose, J
Citation: Rw. Hartmann et al., Synthesis and evaluation of novel steroidal oxime inhibitors of P450 17 (17 alpha-hydroxylase/C17-20-lyase) and 5 alpha-reductase types 1 and 2, J MED CHEM, 43(22), 2000, pp. 4266-4277
Authors:
Wachall, BG
Hector, M
Zhuang, Y
Hartmann, RW
Citation: Bg. Wachall et al., Imidazole substituted biphenyls: A new class of highly potent and in vivo active inhibitors of P450 17 as potential therapeutics for treatment of prostate cancer, BIO MED CH, 7(9), 1999, pp. 1913-1924
Authors:
Le Borgne, M
Marchand, P
Delevoye-Seiller, B
Robert, JM
Le Baut, G
Hartmann, RW
Palzer, M
Citation: M. Le Borgne et al., New selective nonsteroidal aromatase inhibitors: Synthesis and inhibitory activity of 2, 3 or 5-(alpha-azolylbenzyl)-1H-indoles, BIOORG MED, 9(3), 1999, pp. 333-336
Authors:
Baston, E
Hartmann, RW
Citation: E. Baston et Rw. Hartmann, N-substituted 4-(5-indolyl)benzoic acids. Synthesis and evaluation of steroid 5 alpha-reductase type I and II inhibitory activity, BIOORG MED, 9(11), 1999, pp. 1601-1606
Authors:
Haider, N
Hartmann, RW
Steinwender, A
Citation: N. Haider et al., Synthesis of 2-[2-(1-imidazolyl)ethyl]-4-phenylcycloalka[g]phthalazin-1(2H)-ones as thromboxane A(2) synthase inhibitors, ARCH PHARM, 332(11), 1999, pp. 408-409
Authors:
Hartmann, RW
Frotscher, M
Citation: Rw. Hartmann et M. Frotscher, 1-imidazolylcarbonyloxy-substituted tetrahydroquinolines and pyridines: Synthesis and evaluation of P450 TxA2 inhibition, ARCH PHARM, 332(10), 1999, pp. 358-362
Authors:
Zhuang, Y
Hartmann, RW
Citation: Y. Zhuang et Rw. Hartmann, Synthesis and evaluation of azole-substituted 2-aryl-6-methoxy-3,4-dihydronaphthalenes and -naphthalenes as inhibitors of 17 alpha-hydroxylase-C17,20-lyase (P450 17), ARCH PHARM, 332(1), 1999, pp. 25-30
Authors:
Hartmann, RW
Citation: Rw. Hartmann, Ludwig's angina in children, AM FAM PHYS, 60(1), 1999, pp. 109-112
Authors:
Dannhardt, G
Flemmer, L
Hartmann, RW
Kleber, A
Schulze, E
Citation: G. Dannhardt et al., Spectrofluorimetric quantification of malondialdehyde for evaluation of cyclooxygenase-1/thromboxane synthase inhibition, ARCH PHARM, 331(11), 1998, pp. 359-364
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