Authors:
Mensenkamp, AR
Teusink, B
Baller, JFW
Wolters, H
Havinga, R
van Dijk, KW
Havekes, LM
Kuipers, F
Citation: Ar. Mensenkamp et al., Mice expressing only the mutant APOE3Leiden gene show impaired VLDL secretion, ART THROM V, 21(8), 2001, pp. 1366-1372
Authors:
Volger, OL
van der Boom, H
de Wit, ECM
van Duyvenvoorde, W
Hornstra, G
Plat, J
Havekes, LM
Mensink, RP
Princen, HMG
Citation: Ol. Volger et al., Dietary plant stanol esters reduce VLDL cholesterol secretion and bile saturation in apolipoprotein E3-Leiden transgenic mice, ART THROM V, 21(6), 2001, pp. 1046-1052
Authors:
van de Poll, SWE
Romer, TJ
Volger, OL
Delsing, DJM
Schut, TCB
Princen, HMG
Havekes, LM
Jukema, JW
van der Laarse, A
Puppels, GJ
Citation: Swe. Van De Poll et al., Raman spectroscopic evaluation of the effects of diet and lipid-lowering therapy on atherosclerotic plaque development in mice, ART THROM V, 21(10), 2001, pp. 1630-1635
Authors:
Tacken, PJ
van der Zee, A
Beumer, TL
Florijn, RJ
Gijpels, MJJ
Havekes, LM
Frants, RR
van Dijk, KW
Hofker, MH
Citation: Pj. Tacken et al., Effective generation of very low density lipoprotein receptor transgenic mice by overlapping genomic DNA fragments: high testis expression and disturbed spermatogenesis, TRANSGEN RE, 10(3), 2001, pp. 211-221
Authors:
Mulder, M
Blokland, A
van den Berg, DJ
Schulten, H
Bakker, AHF
Terwel, D
Honig, W
de Kloet, ER
Havekes, LM
Steinbusch, HWM
de Lange, ECM
Citation: M. Mulder et al., Apolipoprotein E protects against neuropathology induced by a high-fat diet and maintains the integrity of the blood-brain barrier during aging, LAB INV, 81(7), 2001, pp. 953-960
Authors:
Jong, MC
Rensen, PCN
Dahlmans, VEH
van der Boom, H
van Berkel, TJC
Havekes, LM
Citation: Mc. Jong et al., Apolipoprotein C-III deficiency accelerates triglyceride hydrolysis by lipoprotein lipase in wild-type and apoE knockout mice, J LIPID RES, 42(10), 2001, pp. 1578-1585
Authors:
Teusink, B
Mensenkamp, AR
van der Boom, H
Kuipers, F
van Dijk, KW
Havekes, LM
Citation: B. Teusink et al., Stimulation of the in vivo production of very low density lipoproteins by apolipoprotein E is independent of the presence of the low density lipoprotein receptor, J BIOL CHEM, 276(44), 2001, pp. 40693-40697
Authors:
Kypreos, KE
van Dijk, KW
van der Zee, A
Havekes, LM
Zannis, VI
Citation: Ke. Kypreos et al., Domains of apolipoprotein E contributing to triglyceride and cholesterol homeostasis in vivo - Carboxyl-terminal region 203-299 promotes hepatic verylow density lipoprotein-triglyceride secretion, J BIOL CHEM, 276(23), 2001, pp. 19778-19786
Authors:
Boer, JMA
Feskens, EJM
Kuivenhoven, JA
Schouten, EG
Havekes, LM
Kastelein, JJP
Seidell, JC
Kromhout, D
Citation: Jma. Boer et al., Parental history of myocardial infarction: lipid traits, gene polymorphisms and lifestyle, ATHEROSCLER, 155(1), 2001, pp. 149-156
Authors:
Koopmans, SJ
Jong, MC
Que, I
Dahlmans, VEH
Pijl, H
Radder, JK
Frolich, M
Havekes, LM
Citation: Sj. Koopmans et al., Hyperlipidaemia is associated with increased insulin-mediated glucose metabolism, reduced fatty acid metabolism and normal blood pressure in transgenic mice overexpressing human apolipoprotein C1, DIABETOLOG, 44(4), 2001, pp. 437-443
Authors:
Voshol, PJ
Jong, MC
Dahlmans, VEH
Kratky, D
Levak-Frank, S
Zechner, R
Romijn, JA
Havekes, LM
Citation: Pj. Voshol et al., In muscle-specific lipoprotein lipase-overexpressing mice, muscle triglyceride content is increased without inhibition of insulin-stimulated whole-body and muscle-specific glucose uptake, DIABETES, 50(11), 2001, pp. 2585-2590
Authors:
van Vlijmen, BJM
Gerritsen, G
Franken, AL
Boesten, SM
Kockx, MM
Gijbels, MJ
Vierboom, MP
van Eck, M
van de Water, B
van Berkel, TJC
Havekes, LM
Citation: Bjm. Van Vlijmen et al., Macrophage p53 deficiency leads to enhanced atherosclerosis in APOE3-Leiden transgenic mice, CIRCUL RES, 88(8), 2001, pp. 780-786
Authors:
Delsing, DJM
Offerman, EH
van Duyvenvoorde, W
van der Boom, H
de Wit, ECM
Gijbels, MJJ
van der Laarse, A
Jukema, JW
Havekes, LM
Princen, HMG
Citation: Djm. Delsing et al., Acyl-CoA: Cholesterol acyltransferase inhibitor avasimibe reduces atherosclerosis in addition to its cholesterol-lowering effect in ApoE3-Leiden mice, CIRCULATION, 103(13), 2001, pp. 1778-1786
Authors:
Kypreos, KE
Morani, P
van Dijk, KW
Havekes, LM
Zannis, VI
Citation: Ke. Kypreos et al., The amino-terminal 1-185 domain of ApoE promotes the clearance of lipoprotein remnants in vivo. The carboxy-terminal domain is required for inductionof hyperlipidemia in normal and ApoE-deficient mice, BIOCHEM, 40(20), 2001, pp. 6027-6035
Authors:
de Beer, F
van Dijk, KW
Jong, MC
van Vark, LC
van der Zee, A
Hofker, MH
Fallaux, FJ
Hoeben, RC
Smelt, AHM
Havekes, LM
Citation: F. De Beer et al., Apolipoprotein E2 (Lys146 -> Gln) causes hypertriglyceridemia due to an apolipoprotein E variant-specific inhibition of lipolysis of very low densitylipoproteins-triglycerides, ART THROM V, 20(7), 2000, pp. 1800-1806
Authors:
Post, SM
de Roos, B
Vemeulen, M
Afman, L
Jong, MC
Dahlmans, VEH
Havekes, LM
Stellaard, F
Katan, MB
Princen, HMG
Citation: Sm. Post et al., Cafestol increases serum cholesterol levels in apolipoprotein E3-Leiden transgenic mice by suppression of bile acid synthesis, ART THROM V, 20(6), 2000, pp. 1551-1556
Authors:
de Winther, MPJ
van Dijk, KW
Havekes, LM
Hofker, MH
Citation: Mpj. De Winther et al., Macrophage scavenger receptor class A - A multifunctional receptor in atherosclerosis, ART THROM V, 20(2), 2000, pp. 290-297
Authors:
Van Eck, M
De Winther, MPJ
Herijgers, N
Havekes, LM
Hofker, MH
Groot, PHE
Van Berkel, TJC
Citation: M. Van Eck et al., Effect of human scavenger receptor class A overexpression in bone marrow-derived cells on cholesterol levels and atherosclerosis in ApoE-deficient mice, ART THROM V, 20(12), 2000, pp. 2600-2606
Authors:
Van Eck, M
Herijgers, N
Van Dijk, KW
Havekes, LM
Hofker, MH
Groot, PHE
Van Berkel, TJC
Citation: M. Van Eck et al., Effect of macrophage-derived mouse apoE, human apoE3-Leiden, and human apoE2 (Arg158 -> Cys) on cholesterol levels and atherosclerosis in apoE-deficient mice, ART THROM V, 20(1), 2000, pp. 119-127
Authors:
Jong, MC
Hendriks, WL
van Vark, LC
Dahlmans, VEH
Groener, JEM
Havekes, LM
Citation: Mc. Jong et al., Oxidized VLDL induces less triglyceride accumulation in J774 macrophages than native VLDL due to an impaired extracellular lipolysis, ART THROM V, 20(1), 2000, pp. 144-151
Authors:
Neale, MC
de Knijff, P
Havekes, LM
Boomsma, DI
Citation: Mc. Neale et al., ApoE polymorphism accounts for only part of the genetic variation in quantitative ApoE levels, GENET EPID, 18(4), 2000, pp. 331-340