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Results: 26-50/50
Authors:
Tacken, PJ
de Beer, F
van Vark, LC
Havekes, LM
Hofker, MH
van Dijk, KW
Citation: Pj. Tacken et al., Very-low-density lipoprotein binding to the apolipoprotein E receptor 2 isenhanced by lipoprotein lipase, and does not require apolipoprotein E, BIOCHEM J, 347, 2000, pp. 357-361
Use of transgenic mice to study the role of apolipoprotein E in lipid metabolism and atherosclerosis
Authors:
Van Dijk, KW
Hofker, MH
Havekes, LM
Citation: Kw. Van Dijk et al., Use of transgenic mice to study the role of apolipoprotein E in lipid metabolism and atherosclerosis, INT J TISS, 22(2-3), 2000, pp. 49-58
Authors:
Jong, MC
Havekes, LM
Citation: Mc. Jong et Lm. Havekes, Insights into apolipoprotein C metabolism from transgenic and gene-targeted mice, INT J TISS, 22(2-3), 2000, pp. 59-66
Authors:
de Winther, MPJ
Gijbels, MJJ
Van Dijk, KW
Havekes, LM
Hofker, MH
Citation: Mpj. De Winther et al., Transgenic mouse models to study the role of the macrophage scavenger receptor class A in atherosclerosis, INT J TISS, 22(2-3), 2000, pp. 85-91
Authors:
Mensenkamp, AR
van Luyn, MJA
van Goor, H
Bloks, V
Apostel, F
Greeve, J
Hofker, MH
Jong, MC
van Vlijmen, BJM
Havekes, LM
Kuipers, F
Citation: Ar. Mensenkamp et al., Hepatic lipid accumulation, altered very low density lipoprotein formationand apolipoprotein E deposition in apolipoprotein E3-Leiden transgenic mice, J HEPATOL, 33(2), 2000, pp. 189-198
Authors:
Herijgers, N
de Winther, MPJ
Van Eck, M
Havekes, LM
Hofker, MH
Hoogerbrugge, PM
Van Berkel, TJC
Citation: N. Herijgers et al., Effect of human scavenger receptor class A overexpression in bone marrow-derived cells on lipoprotein metabolism and atherosclerosis in low density lipoprotein receptor knockout mice, J LIPID RES, 41(9), 2000, pp. 1402-1409
Authors:
Rensen, PCN
Jong, MC
van Vark, LC
van der Boom, H
Hendriks, WL
van Berkel, TJC
Biessen, EAL
Havekes, LM
Citation: Pcn. Rensen et al., Apolipoprotein E is resistant to intracellular degradation in vitro and invivo - Evidence for retroendocytosis, J BIOL CHEM, 275(12), 2000, pp. 8564-8571
Authors:
de Man, FHAF
de Beer, F
van der Laarse, A
Jansen, H
Leuven, JAG
Souverijn, JHM
Vroom, TFFP
Schoormans, SCM
Fruchart, JC
Havekes, LM
Smelt, AHM
Citation: Fhaf. De Man et al., The hypolipidemic action of bezafibrate therapy in hypertriglyceridemia ismediated by upregulation of lipoprotein lipase: no effects on VLDL substrate affinity to lipolysis or LDL receptor binding, ATHEROSCLER, 153(2), 2000, pp. 363-371
Authors:
Sijbrands, EJG
Westendorp, RGJ
Lombardi, MP
Havekes, LM
Frants, RR
Kastelein, JJP
Smelt, AHM
Citation: Ejg. Sijbrands et al., Additional risk factors influence excess mortality in heterozygous familial hypercholesterolaemia, ATHEROSCLER, 149(2), 2000, pp. 421-425
Authors:
Lombardi, MP
Redeker, EJW
Defesche, JC
Kamerling, SWA
Trip, MD
Mannens, MMAM
Havekes, LM
Kastelein, JJP
Citation: Mp. Lombardi et al., Molecular genetic testing for familial hypercholesterolemia: spectrum of LDL receptor gene mutations in the Netherlands, CLIN GENET, 57(2), 2000, pp. 116-124
Authors:
Lardenoye, JHP
Delsing, DJM
de Vries, MR
Deckers, MML
Princen, HMG
Havekes, LM
van Hinsbergh, VWM
van Bockel, JH
Quax, PHA
Citation: Jhp. Lardenoye et al., Accelerated atherosclerosis by placement of a perivascular cuff and a cholesterol-rich diet in ApoE3Leiden transgenic mice, CIRCUL RES, 87(3), 2000, pp. 248-253
Authors:
Jong, MC
Hofker, MH
Havekes, LM
Citation: Mc. Jong et al., Role of ApoCs in lipoprotein metabolism - Functional differences between ApoC1, ApoC2, and ApoC3, ART THROM V, 19(3), 1999, pp. 472-484
Authors:
de Beer, F
Hendriks, WL
van Vark, LC
Kamerling, SWA
van Dijk, KW
Hofker, MH
Smelt, AHM
Havekes, LM
Citation: F. De Beer et al., Binding of beta-VLDL to heparan sulfate proteoglycans requires lipoproteinlipase, whereas ApoE only modulates binding affinity, ART THROM V, 19(3), 1999, pp. 633-637
Authors:
van Dijk, KW
van Vlijmen, BJM
de Winther, MPJ
van't Hof, B
van der Zee, A
van der Boom, H
Havekes, LM
Hofker, MH
Citation: Kw. Van Dijk et al., Hyperlipidemia of ApoE2(Arg(158)-Cys) and ApoE3-Leiden transgenic mice is modulated predominantly by LDL receptor expression, ART THROM V, 19(12), 1999, pp. 2945-2951
Authors:
Sijbrands, EJ
Hoffer, MJV
Meinders, AE
Havekes, LM
Frants, RR
Smelt, AHM
De Knijff, P
Citation: Ej. Sijbrands et al., Severe hyperlipidemia in apolipoprotein E2 homozygotes due to a combined effect of hyperinsulinemia and an SstI polymorphism, ART THROM V, 19(11), 1999, pp. 2722-2729
Authors:
Jong, MC
Van Dijk, KW
Dahlmans, VEH
Van der Boom, H
Kobayashi, K
Oka, K
Siest, G
Chan, L
Hofker, MH
Havekes, LM
Citation: Mc. Jong et al., Reversal of hyperlipidaemia in apolipoprotein C1 transgenic mice by adenovirus-mediated gene delivery of the low-density-lipoprotein receptor, but not by the very-low-density-lipoprotein receptor, BIOCHEM J, 338, 1999, pp. 281-287
Authors:
van Dijk, KW
van Vlijmen, BJM
van't Hof, HB
van der Zee, A
Santamarina-Fojo, S
van Berkel, TJC
Havekes, LM
Hofker, MH
Citation: Kw. Van Dijk et al., In LDL receptor-deficient mice, catabolism of remnant lipoproteins requires a high level of apoE but is inhibited by excess apoE, J LIPID RES, 40(2), 1999, pp. 336-344
Authors:
Mensenkamp, AR
Jong, MC
van Goor, H
van Luyn, MJA
Bloks, V
Havinga, R
Voshol, PJ
Hofker, MH
van Dijk, KW
Havekes, LM
Kuipers, F
Citation: Ar. Mensenkamp et al., Apolipoprotein E participates in the regulation of very low density lipoprotein-triglyceride secretion by the liver, J BIOL CHEM, 274(50), 1999, pp. 35711-35718
Authors:
van Vlijmen, BJM
Rohlmann, A
Page, ST
Bensadoun, A
Bos, IST
van Berkel, TJC
Havekes, LM
Herz, J
Citation: Bjm. Van Vlijmen et al., An extrahepatic receptor-associated protein-sensitive mechanism is involved in the metabolism of triglyceride-rich lipoproteins, J BIOL CHEM, 274(49), 1999, pp. 35219-35226
Authors:
de Winther, MPJ
van Dijk, KW
van Vlijmen, BJM
Gijbels, MJJ
Heus, JJ
Wijers, ER
van den Bos, AC
Breuer, M
Frants, RR
Havekes, LM
Hofker, MH
Citation: Mpj. De Winther et al., Macrophage specific overexpression of the human macrophage scavenger receptor in transgenic mice, using a 180-kb yeast artificial chromosome, leads to enhanced foam cell formation of isolated peritoneal macrophages, ATHEROSCLER, 147(2), 1999, pp. 339-347
Authors:
de Winther, MPJ
Gijbels, MJJ
van Dijk, KW
van Gorp, PJJ
Suzuki, H
Kodama, T
Frants, RR
Havekes, LM
Hofker, MH
Citation: Mpj. De Winther et al., Scavenger receptor deficiency leads to more complex atherosclerotic lesions in APOE3Leiden transgenic mice, ATHEROSCLER, 144(2), 1999, pp. 315-321
Authors:
Gijbels, MJJ
van der Cammen, M
van der Laan, LJW
Emeis, JJ
Havekes, LM
Hofker, MH
Kraal, G
Citation: Mjj. Gijbels et al., Progression and regression of atherosclerosis in APOE3-Leiden transgenic mice: an immunohistochemical study, ATHEROSCLER, 143(1), 1999, pp. 15-25
Authors:
Boer, JMA
Kuivenhoven, JA
Feskens, EJM
Schouten, EG
Havekes, LM
Seidell, JC
Kastelein, JJP
Kromhout, D
Citation: Jma. Boer et al., Physical activity modulates the effect of a lipoprotein lipase mutation (D9N) on plasma lipids and lipoproteins, CLIN GENET, 56(2), 1999, pp. 158-163
Authors:
Mulder, M
Ravid, R
Swaab, DF
de Kloet, ER
Haasdijk, ED
Julk, J
van der Boom, J
Havekes, LM
Citation: M. Mulder et al., Reduced levels of cholesterol, phospholipids, and fatty acids in cerebrospinal fluid of Alzheimer disease patients are not related to apolipoprotein E4, ALZ DIS A D, 12(3), 1998, pp. 198-203
Authors:
Jong, MC
Dahlmans, VEH
Princen, HMG
Hofker, MH
Havekes, LM
Citation: Mc. Jong et al., Effects of fenofibrate on hyperlipidemia and postprandial triglyceride metabolism in human apolipoprotein C1 transgenic mice, ATHEROSCLER, 141, 1998, pp. S77-S80