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Results: 1-25/51
Authors:
Bergsten, E
Uutela, M
Li, XR
Pietras, K
Ostman, A
Heldin, CH
Alitalo, K
Eriksson, U
Citation: E. Bergsten et al., PDGF-D is a specific, protease-activated ligand for the PDGF beta-receptor, NAT CELL BI, 3(5), 2001, pp. 512-516
Authors:
Heldin, CH
Citation: Ch. Heldin, Signal transduction: Multiple pathways, multiple options for therapy, STEM CELLS, 19(4), 2001, pp. 295-303
Authors:
Kurisaki, A
Kose, S
Yoneda, Y
Heldin, CH
Moustakas, A
Citation: A. Kurisaki et al., Transforming growth-factor beta induces nuclear import of Smad3 in an importin-beta 1 and Ran-dependent manner (vol 12, pg 1079, 2001), MOL BIOL CE, 12(9), 2001, pp. NIL_3-NIL_3
Authors:
Kurisaki, A
Kose, S
Yoneda, Y
Heldin, CH
Moustakas, A
Citation: A. Kurisaki et al., Transforming growth factor-beta induces nuclear import of Smad3 in an importin-beta 1 and Ran-dependent manner, MOL BIOL CE, 12(4), 2001, pp. 1079-1091
Authors:
Rosendahl, A
Checchin, D
Fehniger, TE
ten Dijke, P
Heldin, CH
Sideras, P
Citation: A. Rosendahl et al., Activation of the TGF-beta/activin-Smad2 pathway during allergic airway inflammation, AM J RESP C, 25(1), 2001, pp. 60-68
Authors:
Yakmovych, I
Ten Dijke, P
Heldin, CH
Souchelnytskyi, S
Citation: I. Yakmovych et al., Regulation of Smad signaling by protein kinase C, FASEB J, 15(3), 2001, pp. 553-555
Authors:
Itoh, F
Asao, H
Sugamura, K
Heldin, CH
ten Dijke, P
Itoh, S
Citation: F. Itoh et al., Promoting bone morphogenetic protein signaling through negative regulationof inhibitory Smads, EMBO J, 20(15), 2001, pp. 4132-4142
Authors:
Ostman, A
Heldin, CH
Citation: A. Ostman et Ch. Heldin, Involvement of platelet-derived growth factor in disease: Development of specific antagonists, ADV CANC R, 80, 2001, pp. 1-38
Authors:
Heldin, CH
Ericsson, J
Citation: Ch. Heldin et J. Ericsson, Signal transduction - RIPping tyrosine kinase receptors apart, SCIENCE, 294(5549), 2001, pp. 2111
Authors:
Shimizu, A
Persson, C
Heldin, CH
Ostman, A
Citation: A. Shimizu et al., Ligand stimulation reduces platelet-derived growth factor beta-receptor susceptibility to tyrosine dephosphorylation, J BIOL CHEM, 276(30), 2001, pp. 27749-27752
Authors:
Pulaski, L
Landstrom, M
Heldin, CH
Souchelnytskyi, S
Citation: L. Pulaski et al., Phosphorylation of Smad7 at Ser-249 does not interfere with its inhibitoryrole in transforming growth factor-beta-dependent signaling but affects Smad7-dependent transcriptional activation, J BIOL CHEM, 276(17), 2001, pp. 14344-14349
Authors:
Ronnstrand, L
Heldin, CH
Citation: L. Ronnstrand et Ch. Heldin, Mechanisms of platelet-derived growth factor-induced chemotaxis, INT J CANC, 91(6), 2001, pp. 757-762
Authors:
Pietras, K
Ostman, A
Sjoquist, M
Buchdunger, E
Reed, RK
Heldin, CH
Rubin, K
Citation: K. Pietras et al., Inhibition of platelet-derived growth factor receptors reduces interstitial hypertension and increases transcapillary transport in tumors, CANCER RES, 61(7), 2001, pp. 2929-2934
Authors:
Sjoblom, T
Shimizu, A
O'Brien, KP
Pietras, K
Dal Cin, P
Buchdunger, E
Dumanski, JP
Ostman, A
Heldin, CH
Citation: T. Sjoblom et al., Growth inhibition of dermatofibrosarcoma protuberans tumors by the platelet-derived growth factor receptor antagonist STI571 through induction of apoptosis, CANCER RES, 61(15), 2001, pp. 5778-5783
Authors:
Heldin, CH
Moustakas, A
Souchelnytskyi, S
Itoh, S
ten Dijke, P
Citation: Ch. Heldin et al., Signal transduction mechanisms for members of the TGF-beta family, PROG INFLAM, 2001, pp. 11-40
Authors:
Li, XR
Ponten, A
Aase, K
Karlsson, L
Abramsson, A
Uutela, M
Backstrom, G
Hellstrom, M
Bostrom, H
Li, H
Soriano, P
Betscholtz, C
Heldin, CH
Alitalo, K
Ostman, A
Eriksson, U
Citation: Xr. Li et al., PDGF-C is a new protease-activated ligand for the PDGF alpha-receptor, NAT CELL BI, 2(5), 2000, pp. 302-309
Authors:
Leppanen, O
Janjic, N
Carlsson, MA
Pietras, K
Levin, M
Vargeese, C
Green, LS
Bergqvist, D
Ostman, A
Heldin, CH
Citation: O. Leppanen et al., Intimal hyperplasia recurs after removal of PDGF-AB and -BB inhibition in the rat carotid artery injury model, ART THROM V, 20(11), 2000, pp. E89-E95
Authors:
ten Dijke, P
Miyazono, K
Heldin, CH
Citation: P. Ten Dijke et al., Signaling inputs converge on nuclear effecters in TGF-beta signaling, TRENDS BIOC, 25(2), 2000, pp. 64-70
Authors:
Landstrom, M
Heldin, NE
Bu, SZ
Hermansson, A
Itoh, S
ten Dijke, P
Heldin, CH
Citation: M. Landstrom et al., Smad7 mediates apoptosis induced by transforming growth factor beta in prostatic carcinoma cells, CURR BIOL, 10(9), 2000, pp. 535-538
Authors:
Moren, A
Itoh, S
Moustakas, A
ten Dijke, P
Heldin, CH
Citation: A. Moren et al., Functional consequences of tumorigenic missense mutations in the amino-terminal domain of Smad4, ONCOGENE, 19(38), 2000, pp. 4396-4404
Authors:
Tallquist, MD
Klinghoffer, RA
Heuchel, R
Mueting-Nelsen, PF
Corrin, PD
Heldin, CH
Johnson, RJ
Soriano, P
Citation: Md. Tallquist et al., Retention of PDGFR-beta function in mice in the absence of phosphatidylinositol 3 '-kinase and phospholipase C gamma signaling pathways, GENE DEV, 14(24), 2000, pp. 3179-3190
Authors:
Itoh, S
Ericsson, J
Nishikawa, J
Heldin, CH
ten Dijke, P
Citation: S. Itoh et al., The transcriptional co-activator P/CAF potentiates TGF-beta/Smad signaling, NUCL ACID R, 28(21), 2000, pp. 4291-4298
Authors:
Paukku, K
Valgeirsdottir, S
Saharinen, P
Bergman, M
Heldin, CH
Silvennoinen, O
Citation: K. Paukku et al., Platelet-derived growth factor (PDGF)-induced activation of signal transducer and activator of transcription (Stat) 5 is mediated by PDGF beta-receptor and is not dependent on c-Src, Fyn, Jak1 or Jak2 kinases, BIOCHEM J, 345, 2000, pp. 759-766
Authors:
Miyazono, K
Ten Dijke, P
Heldin, CH
Citation: K. Miyazono et al., TGF-beta signaling by Smad proteins, ADV IMMUNOL, 75, 2000, pp. 115-157
Authors:
Hooshmand-Rad, R
Hajkova, L
Klint, P
Karlsson, R
Vanhaesebroeck, B
Claesson-Welsh, L
Heldin, CH
Citation: R. Hooshmand-rad et al., The PI 3-kinase isoforms p110 alpha and p110 beta have differential roles in PDGF- and insulin-mediated signaling, J CELL SCI, 113(2), 2000, pp. 207-214