Authors:
Hombach, A
Muche, JM
Gerken, M
Gellrich, S
Heuser, C
Pohl, C
Sterry, W
Abken, H
Citation: A. Hombach et al., T cells engrafted with a recombinant anti-CD30 receptor target autologous CD30(+) cutaneous lymphoma cells, GENE THER, 8(11), 2001, pp. 891-895
Authors:
Rappl, G
Kapsokefalou, A
Heuser, C
Rossler, M
Ugurel, S
Tilgen, W
Reinhold, U
Abken, H
Citation: G. Rappl et al., Dermal fibroblasts sustain proliferation of activated T cells via membrane-bound interleukin-15 upon long-term stimulation with tumor necrosis factor-alpha, J INVES DER, 116(1), 2001, pp. 102-109
Authors:
Hombach, A
Heuser, C
Marquardt, T
Wieczarkowiecz, A
Groneck, V
Pohl, C
Abken, H
Citation: A. Hombach et al., CD4(+) T cells engrafted with a recombinant immunoreceptor efficiently lyse target cells in a MHC antigen- and Fas-independent fashion, J IMMUNOL, 167(2), 2001, pp. 1090-1096
Authors:
Hombach, A
Wieczarkowiecz, A
Marquardt, T
Heuser, C
Usai, L
Pohl, C
Seliger, B
Abken, H
Citation: A. Hombach et al., Tumor-specific T cell activation by recombinant immunoreceptors: CD3 zeta signaling and CD28 costimulation are simultaneously required for efficient IL-2 secretion and can ge integrated into one combined CD28/CD3 zeta signaling receptor molecule, J IMMUNOL, 167(11), 2001, pp. 6123-6131
Authors:
Hombach, A
Sent, D
Schneider, C
Heuser, C
Koch, D
Pohl, C
Seliger, B
Abken, H
Citation: A. Hombach et al., T-cell activation by recombinant receptors: CD28 costimulation is requiredfor interleukin 2 secretion and receptor-mediated T-cell proliferation butdoes not affect receptor-mediated target cell lysis, CANCER RES, 61(5), 2001, pp. 1976-1982
Authors:
Hombach, A
Heuser, C
Gerken, M
Fischer, B
Lewalter, K
Diehl, V
Pohl, C
Abken, H
Citation: A. Hombach et al., T cell activation by recombinant Fc epsilon RI gamma-chain immune receptors: an extracellular spacer domain impairs antigen-dependent T cell activation but not antigen recognition, GENE THER, 7(12), 2000, pp. 1067-1075
Authors:
Steffens, S
Frank, S
Fischer, U
Heuser, C
Meyer, KL
Dobberstein, KU
Rainov, NG
Kramm, CM
Citation: S. Steffens et al., Enhanced green fluorescent protein fusion proteins of herpes simplex virustype 1 thymidine kinase and cytochrome P4504B1: Applications for prodrug-activating gene therapy, CANC GENE T, 7(5), 2000, pp. 806-812
Authors:
Hombach, A
Heuser, C
Sircar, R
Tillmann, T
Diehl, V
Pohl, C
Abken, H
Citation: A. Hombach et al., Characterization of a chimeric T-cell receptor with specificity for the Hodgkin's lymphoma-associated CD30 antigen, J IMMUNOTH, 22(6), 1999, pp. 473-480
Authors:
Hombach, A
Koch, D
Sircar, R
Heuser, C
Diehl, V
Kruis, W
Pohl, C
Abken, H
Citation: A. Hombach et al., A chimeric receptor that selectively targets membrane-bound carcinoembryonic antigen (mCEA) in the presence of soluble CEA, GENE THER, 6(2), 1999, pp. 300-304
Authors:
Hombach, A
Pohl, C
Heuser, C
Sircar, R
Koch, D
Diehl, V
Abken, H
Citation: A. Hombach et al., Generation of the single chain antibody fragment conserves the idiotypic profile of the anti-CD30 monoclonal antibody HRS3. (vol 48, pg 497, 1998), SC J IMMUN, 50(2), 1999, pp. 232-232
Authors:
Reinhold, U
Liu, LD
Ludtke-Handjery, HC
Heuser, C
Hombach, A
Wang, XH
Tilgen, W
Ferrone, S
Abken, H
Citation: U. Reinhold et al., Specific lysis of melanoma cells by receptor grafted T cells is enhanced by anti-idiotypic monoclonal antibodies directed to the scFv domain of the receptor, J INVES DER, 112(5), 1999, pp. 744-750