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Results: 1-25/30
Authors:
Hill, BT
Fahy, J
Citation: Bt. Hill et J. Fahy, Tubulin-interacting agents - Preface, CUR PHARM D, 7(13), 2001, pp. NIL_2-NIL_2
Authors:
Hill, BT
Citation: Bt. Hill, Vinflunine, a second generation novel Vinca alkaloid with a distinctive pharmacological profile, now in clinical development and prospects for futuremitotic blockers, CUR PHARM D, 7(13), 2001, pp. 1199-1212
Authors:
Fahy, J
Hill, BT
Citation: J. Fahy et Bt. Hill, Tubulin-interacting agents - Epilogue, CUR PHARM D, 7(13), 2001, pp. 1297-1301
Authors:
Kruczynski, A
Hill, BT
Citation: A. Kruczynski et Bt. Hill, Vinflunine, the latest Vinca alkaloid in clinical development - A review of its preclinical anticancer properties, CR R ONC H, 40(2), 2001, pp. 159-173
Authors:
Etievant, C
Kruczynski, A
Barret, JM
Tait, AS
Kavallaris, M
Hill, BT
Citation: C. Etievant et al., Markedly diminished drug resistance-inducing properties of vinflunine (20 ',20 '-difluoro-3 ',4 '-dihydrovinorelbine) relative to vinorelbine, identified in murine and human tumour cells in vivo and in vitro, CANC CHEMOT, 48(1), 2001, pp. 62-70
Authors:
Ngan, VK
Bellman, K
Hill, BT
Wilson, L
Jordan, MA
Citation: Vk. Ngan et al., Mechanism of mitotic block and inhibition of cell proliferation by the semisynthetic vinca alkaloids vinorelbine and its newer derivative vinflunine, MOLEC PHARM, 60(1), 2001, pp. 225-232
Authors:
Tichy, SE
Hill, BT
Campbell, JL
Kenttamaa, HI
Citation: Se. Tichy et al., Synthesis and characterization of a distonic nitrene ion: Gas-phase reactivity of singlet and triplet N-phenyl-3-nitrenopyridinium ion, J AM CHEM S, 123(32), 2001, pp. 7923-7924
Authors:
Likhotvorik, I
Zhu, ZD
Tae, EL
Tippmann, E
Hill, BT
Platz, MS
Citation: I. Likhotvorik et al., Carbomethoxychlorocarbene: Spectroscopy, theory, chemistry and kinetics, J AM CHEM S, 123(25), 2001, pp. 6061-6068
Authors:
Perrin, D
Gras, S
van Hille, B
Hill, BT
Citation: D. Perrin et al., Expression in yeast and purification of functional recombinant human poly(ADP-ribose)polymerase (PARP). Comparative pharmacological profile with thatof the rat enzyme, J ENZ INHIB, 15(5), 2000, pp. 461-469
Authors:
Workman, RD
Lewis, MJ
Hill, BT
Citation: Rd. Workman et al., Enhancing the financial performance of a health system laboratory network using an information system, AM J CLIN P, 114(1), 2000, pp. 9-15
Authors:
Hill, BT
Perrin, D
Kruczynski, A
Citation: Bt. Hill et al., Inhibition of RAS-targeted prenylation: protein farnesyl transferase inhibitors revisited, CR R ONC H, 33(1), 2000, pp. 7-23
Authors:
Dempke, W
Voigt, W
Grothey, A
Hill, BT
Schmoll, HJ
Citation: W. Dempke et al., Cisplatin resistance and oncogene - a review, ANTI-CANC D, 11(4), 2000, pp. 225-236
Authors:
Hill, BT
Moran, E
Etievant, C
Perrin, D
Masterson, A
Larkin, A
Whelan, RDH
Citation: Bt. Hill et al., Low-dose twice-daily fractionated X-irradiation of ovarian tumor cells in vitro generates drug-resistant cells overexpressing two multidrug resistance-associated proteins, P-glycoprotein and MRP1, ANTI-CANC D, 11(3), 2000, pp. 193-200
Authors:
van Hille, B
Etievant, C
Barret, JM
Kruczynski, A
Hill, BT
Citation: B. Van Hille et al., Characterization of the biological and biochemical activities of F 11782 and the bisdioxopiperazines, ICRF-187 and ICRF-193, two types of topoisomerase II catalytic inhibitors with distinctive mechanisms of action, ANTI-CANC D, 11(10), 2000, pp. 829-841
Authors:
Etievant, C
Kruczynski, A
Barret, JM
Perrin, D
van Hille, B
Guminski, Y
Hill, BT
Citation: C. Etievant et al., F 11782, a dual inhibitor of topoisomerases I and II with an original mechanism of action in vitro, and markedly superior in vivo antitumour activity, relative to three other dual topoisomerase inhibitors, intoplicin, aclarubicin and TAS-103, CANC CHEMOT, 46(2), 2000, pp. 101-113
Authors:
Barret, JM
Etievant, C
Hill, BT
Citation: Jm. Barret et al., In vitro synergistic effects of vinflunine, a novel fluorinated vinca alkaloid, in combination with other anticancer drugs, CANC CHEMOT, 45(6), 2000, pp. 471-476
Authors:
Barret, JM
Montaudon, D
Etievant, C
Perrin, D
Kruczynski, A
Robert, J
Hill, BT
Citation: Jm. Barret et al., Detection of DNA-strand breaks in cells treated with F 11782, a catalytic inhibitor of topoisomerases I and II, ANTICANC R, 20(6B), 2000, pp. 4557-4562
Authors:
Ngan, VK
Bellman, K
Panda, D
Hill, BT
Jordan, MA
Wilson, L
Citation: Vk. Ngan et al., Novel actions of the antitumor drugs vinflunine and vinorelbine on microtubules, CANCER RES, 60(18), 2000, pp. 5045-5051
Authors:
Kruczynski, A
Etievant, C
Perrin, D
Imbert, T
Colpaert, F
Hill, BT
Citation: A. Kruczynski et al., Preclinical antitumour activity of F 11782, a novel dual catalytic inhibitor of topoisomerases, BR J CANC, 83(11), 2000, pp. 1516-1524
Authors:
Lobert, S
Fahy, J
Hill, BT
Duflos, A
Etievant, C
Correia, JJ
Citation: S. Lobert et al., Vinca alkaloid-induced tubulin spiral formation correlates with cytotoxicity in the leukemic L1210 cell line, BIOCHEM, 39(39), 2000, pp. 12053-12062
Authors:
Perrin, D
van Hille, B
Barret, JM
Kruczynski, A
Etievant, C
Imbert, T
Hill, BT
Citation: D. Perrin et al., F 11782, a novel epipodophylloid non-intercalating dual catalytic inhibitor of topoisomerases I and II with an original mechanism of action, BIOCH PHARM, 59(7), 2000, pp. 807-819
Authors:
Artau, A
Nizzi, KE
Hill, BT
Sunderlin, LS
Wenthold, PG
Citation: A. Artau et al., Bond dissociation energy in trifluoride ion, J AM CHEM S, 122(43), 2000, pp. 10667-10670
Authors:
Hill, BT
Poutsma, JC
Chyall, LJ
Hu, J
Squires, RR
Citation: Bt. Hill et al., Distonic ions of the "Ate" class, J AM SOC M, 10(9), 1999, pp. 896-906
Authors:
Hill, BT
Fiebig, HH
Waud, WR
Poupon, MF
Colpaert, F
Kruczynski, A
Citation: Bt. Hill et al., Superior in vivo experimental antitumour activity of vinflunine, relative to vinorelbine, in a panel of human tumour xenografts, EUR J CANC, 35(3), 1999, pp. 512-520
Authors:
Jean-Decoster, C
Brichese, L
Barret, JM
Tollon, Y
Kruczynski, A
Hill, BT
Wright, M
Citation: C. Jean-decoster et al., Vinflunine, a new vinca alkaloid: cytotoxicity, cellular accumulation and action on the interphasic and mitotic microtubule cytoskeleton of PtK2 cells, ANTI-CANC D, 10(6), 1999, pp. 537-543