Authors:
Sugden, MC
Langdown, ML
Munns, MJ
Holness, MJ
Citation: Mc. Sugden et al., Maternal glucocorticoid treatment modulates placental leptin and leptin receptor expression and materno-fetal leptin physiology during late pregnancy, and elicits hypertension associated with hyperleptinaemia in the early-growth-retarded adult offspring, EUR J ENDOC, 145(4), 2001, pp. 529-539
Citation: Mj. Holness, Enhanced glucose uptake into adipose tissue induced by early growth restriction augments excursions in plasma leptin response evoked by changes in insulin status, INT J OBES, 25(12), 2001, pp. 1775-1781
Citation: Mj. Holness et Mc. Sugden, Antecedent protein restriction and high-fat feeding interactively sensitise the leptin response to elevated insulin, MOL C ENDOC, 173(1-2), 2001, pp. 53-62
Authors:
Langdown, ML
Smith, ND
Sugden, MC
Holness, MJ
Citation: Ml. Langdown et al., Excessive glucocorticoid exposure during late intrauterine development modulates the expression of cardiac uncoupling proteins in adult hypertensive male offspring, PFLUG ARCH, 442(2), 2001, pp. 248-255
Citation: Ml. Langdown et al., Early growth retardation induced by excessive exposure to glucocorticoids in utero selectively increases cardiac GLUT1 protein expression and Akt/protein kinase B activity in adulthood, J ENDOCR, 169(1), 2001, pp. 11-22
Citation: Mj. Holness et Mc. Sugden, Dexamethasone during late gestation exacerbates peripheral insulin resistance and selectively targets glucose-sensitive functions in beta cell and liver, ENDOCRINOL, 142(9), 2001, pp. 3742-3748
Authors:
Sugden, MC
Bulmer, K
Gibbons, GF
Holness, MJ
Citation: Mc. Sugden et al., Role of peroxisome proliferator-activated receptor-alpha in the mechanism underlying changes in renal pyruvate dehydrogenase kinase isoform 4 proteinexpression in starvation and after refeeding, ARCH BIOCH, 395(2), 2001, pp. 246-252
Authors:
Sugden, MC
Langdown, ML
Harris, RA
Holness, MJ
Citation: Mc. Sugden et al., Expression and regulation of pyruvate dehydrogenase kinase isoforms in thedeveloping rat heart and in adulthood: role of thyroid hormone status and lipid supply, BIOCHEM J, 352, 2000, pp. 731-738
Citation: Mj. Holness et al., Early-life programming of susceptibility to dysregulation of glucose metabolism and the development of Type 2 diabetes mellitus, BIOCHEM J, 349, 2000, pp. 657-665
Authors:
Sugden, MC
Kraus, A
Harris, RA
Holness, MJ
Citation: Mc. Sugden et al., Fibre-type specific modification of the activity and regulation of skeletal muscle pyruvate dehydrogenase kinase (PDK) by prolonged starvation and refeeding is associated with targeted regulation of PDK isoenzyme 4 expression, BIOCHEM J, 346, 2000, pp. 651-657
Authors:
Sugden, MC
Lall, HS
Harris, RA
Holness, MJ
Citation: Mc. Sugden et al., Selective modification of the pyruvate dehydrogenase kinase isoform profile in skeletal muscle in hyperthyroidism: implications for the regulatory impact of glucose on fatty acid oxidation, J ENDOCR, 167(2), 2000, pp. 339-345
Authors:
Holness, MJ
Kraus, A
Harris, RA
Sugden, MC
Citation: Mj. Holness et al., Targeted upregulation of pyruvate dehydrogenase kinase (PDK)-4 in slow-twitch skeletal muscle underlies the stable modification of the regulatory characteristics of PDK induced by high-fat feeding, DIABETES, 49(5), 2000, pp. 775-781
Citation: Mc. Sugden et al., Caloric restriction leads to regional specialisation of adipocyte functionin the rat, BBA-MOL C B, 1437(2), 1999, pp. 202-213
Citation: Mj. Holness et Mc. Sugden, The impact of increased dietary lipid on the regulation of glucose uptake and oxidation by insulin in brown- and a range of white-adipose-tissue depots in vivo, INT J OBES, 23(6), 1999, pp. 629-638
Citation: Mj. Holness et Mc. Sugden, Antecedent protein restriction exacerbates development of impaired insulinaction after high-fat feeding, AM J P-ENDO, 39(1), 1999, pp. E85-E93
Citation: Mc. Sugden et al., Substrate interactions in the short- and long-term regulation of renal glucose oxidation, METABOLISM, 48(6), 1999, pp. 707-715
Authors:
Sugden, MC
Priestman, DA
Orfali, KA
Holness, MJ
Citation: Mc. Sugden et al., Hyperthyroidism facilitates cardiac fatty acid oxidation through altered regulation of cardiac carnitine palmitoyltransferase: Studies in vivo and with cardiac myocytes, HORMONE MET, 31(5), 1999, pp. 300-306
Citation: Mj. Holness et Mc. Sugden, In late pregnancy insulin-dependent glucose transport phosphorylation is selectively impaired and activation of glycogen synthase by insulin facilitated in skeletal muscles of 24-h starved rats, DIABETOLOG, 42(7), 1999, pp. 802-811
Citation: Mj. Holness et al., Protein restriction during early development enhances insulin responsiveness but selectively impairs sensitivity to insulin at low concentrations in white adipose tissue during a later pregnancy, BR J NUTR, 81(6), 1999, pp. 481-489