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Results: 1-25/29
Authors:
Willemsen, RA
Debets, R
Hart, E
Hoogenboom, HR
Bolhuis, RLH
Chames, P
Citation: Ra. Willemsen et al., A phage display selected Fab fragment with MHC class I-restricted specificity for MAGE-A1 allows for retargeting of primary human T lymphocytes, GENE THER, 8(21), 2001, pp. 1601-1608
Authors:
Roovers, RC
van der Linden, E
de Bruine, AP
Arends, JW
Hoogenboom, HR
Citation: Rc. Roovers et al., Identification of colon tumour-associated antigens by phage antibody selections on primary colorectal carcinoma, EUR J CANC, 37(4), 2001, pp. 542-549
Authors:
Roovers, RC
van der Linden, E
de Bruine, AP
Arends, JW
Hoogenboom, HR
Citation: Rc. Roovers et al., In vitro characterisation of a monovalent and bivalent form of a fully human anti Ep-CAM phage antibody, CANCER IMMU, 50(1), 2001, pp. 51-59
Authors:
van den Beucken, T
van Neer, N
Sablon, E
Desmet, J
Celis, L
Hoogenboom, HR
Hufton, SE
Citation: T. Van Den Beucken et al., Building novel binding ligands to B7.1 and B7.2 based on human antibody single variable light chain domains, J MOL BIOL, 310(3), 2001, pp. 591-601
Authors:
Todorovska, A
Roovers, RC
Dolezal, O
Kortt, AA
Hoogenboom, HR
Hudson, PJ
Citation: A. Todorovska et al., Design and application of diabodies, triabodies and tetrabodies for cancertargeting, J IMMUNOL M, 248(1-2), 2001, pp. 47-66
Authors:
Roovers, RC
van der Linden, E
Zulema, H
de Bruine, A
Arends, JW
Hoogenboom, HR
Citation: Rc. Roovers et al., Evidence for a bias toward intracellular antigens in the local humoral anti-tumor immune response of a colorectal cancer patient revealed by phage display, INT J CANC, 93(6), 2001, pp. 832-840
Authors:
Hoogenboom, HR
Chames, P
Citation: Hr. Hoogenboom et P. Chames, Natural and designer binding sites made by phage display technology, IMMUNOL TOD, 21(8), 2000, pp. 371-378
Authors:
Chames, P
Hufton, SE
Coulie, PG
Uchanska-Ziegler, B
Hoogenboom, HR
Citation: P. Chames et al., Direct selection of a human antibody fragment directed against the tumor T-cell epitope HLA-A1-MAGE-A1 from a nonimmunized phage-Fab library, P NAS US, 97(14), 2000, pp. 7969-7974
Authors:
Beiboer, SHW
Reurs, A
Roovers, RC
Arends, JW
Whitelegg, NR
Rees, AR
Hoogenboom, HR
Citation: Shw. Beiboer et al., Guided selection of a pan carcinoma specific antibody reveals similar binding characteristics yet structural divergence between the original murine antibody and its human equivalent, J MOL BIOL, 296(3), 2000, pp. 833-849
Authors:
Hufton, SE
van Neer, N
van den Beuken, T
Desmet, J
Sablon, E
Hoogenboom, HR
Citation: Se. Hufton et al., Development and application of cytotoxic T lymphocyte-associated antigen 4as a protein scaffold for the generation of novel binding ligands, FEBS LETTER, 475(3), 2000, pp. 225-231
Authors:
Lener, M
Horn, IR
Cardinale, A
Messina, S
Nielsen, UB
Rybak, SM
Hoogenboom, HR
Cattaneo, A
Biocca, S
Citation: M. Lener et al., Diverting a protein from its cellular location by intracellular antibodies- The case of p21Ras, EUR J BIOCH, 267(4), 2000, pp. 1196-1205
Authors:
Klimka, A
Matthey, B
Roovers, RC
Barth, S
Arends, JW
Engert, A
Hoogenboom, HR
Citation: A. Klimka et al., Human anti-CD30 recombinant antibodies by guided phage antibody selection using cell panning, BR J CANC, 83(2), 2000, pp. 252-260
Authors:
Nuttall, SD
Rousch, MJM
Irving, RA
Hufton, SE
Hoogenboom, HR
Hudson, PJ
Citation: Sd. Nuttall et al., Design and expression of soluble CTLA-4 variable domain as a scaffold for the display of functional polypeptides, PROTEINS, 36(2), 1999, pp. 217-227
Authors:
Andersson, E
Henderikx, P
Krambovitis, E
Hoogenboom, HR
Borrebaeck, CAK
Citation: E. Andersson et al., A tandem repeat of MUC1 core protein induces a weak in vitro immune response in human B cells, CANCER IMMU, 47(5), 1999, pp. 249-256
Authors:
Pelsers, MMAL
Lutgerink, JT
van Nieuwenhoven, FA
Tandon, NN
van der Vusse, GJ
Arends, JW
Hoogenboom, HR
Glatz, JFC
Citation: Mmal. Pelsers et al., A sensitive immunoassay for rat fatty acid translocase (CD36) using phage antibodies selected on cell transfectants: abundant presence of fatty acid translocase CD36 in cardiac and red skeletal muscle and up-regulation in diabetes, BIOCHEM J, 337, 1999, pp. 407-414
Authors:
Hufton, SE
Moerkerk, PT
Meulemans, EV
de Bruine, A
Arends, JW
Hoogenboom, HR
Citation: Se. Hufton et al., Phage display of cDNA repertoires: the pVI display system and its applications for the selection of immunogenic ligands, J IMMUNOL M, 231(1-2), 1999, pp. 39-51
Authors:
Mutuberria, R
Hoogenboom, HR
van der Linden, E
de Bruine, AP
Roovers, RC
Citation: R. Mutuberria et al., Model systems to study the parameters determining the success of phage antibody selections on complex antigens, J IMMUNOL M, 231(1-2), 1999, pp. 65-81
Authors:
Newton, DL
Pollock, D
DiTullio, P
Echelard, Y
Harvey, M
Wilburn, B
Williams, J
Hoogenboom, HR
Raus, JCM
Meade, HM
Rybak, SM
Citation: Dl. Newton et al., Antitransferrin receptor antibody-RNase fusion protein expressed in the mammary gland of transgenic mice, J IMMUNOL M, 231(1-2), 1999, pp. 159-167
Authors:
de Haard, HJ
van Neer, N
Reurs, A
Hufton, SE
Roovers, RC
Henderikx, P
de Bruine, AP
Arends, JW
Hoogenboom, HR
Citation: Hj. De Haard et al., A large non-immunized human Fab fragment phage library that permits rapid isolation and kinetic analysis of high affinity antibodies, J BIOL CHEM, 274(26), 1999, pp. 18218-18230
Authors:
Manzke, O
Fitzgerald, KJ
Holliger, P
Klock, J
Span, M
Fleischmann, B
Hescheler, J
Liu, QH
Johnson, KS
Diehl, V
Hoogenboom, HR
Bohlen, H
Citation: O. Manzke et al., CD3x anti-nitrophenyl bispecific diabodies: Universal immunotherapeutic tools for retargeting T cells to tumors, INT J CANC, 82(5), 1999, pp. 700-708
Authors:
Hufton, SE
Moerkerk, PT
Brandwijk, R
de Bruine, AP
Arends, JW
Hoogenboom, HR
Citation: Se. Hufton et al., A profile of differentially expressed genes in primary colorectal cancer using suppression subtractive hybridization, FEBS LETTER, 463(1-2), 1999, pp. 77-82
Authors:
Horn, IR
Wittinghofer, A
de Bruine, AP
Hoogenboom, HR
Citation: Ir. Horn et al., Selection of phage-displayed Fab antibodies on the active conformation of Ras yields a high affinity conformation-specific antibody preventing the binding of c-Raf kinase to Ras, FEBS LETTER, 463(1-2), 1999, pp. 115-120
Authors:
Persic, L
Horn, IR
Rybak, S
Cattaneo, A
Hoogenboom, HR
Bradbury, A
Citation: L. Persic et al., Single-chain variable fragments selected on the 57-76 p21Ras neutralising epitope from phage antibody libraries recognise the parental protein, FEBS LETTER, 443(2), 1999, pp. 112-116
Authors:
Hoogenboom, HR
Lutgerink, JT
Pelsers, MMAL
Rousch, MJMM
Coote, J
van Neer, N
de Bruine, A
van Nieuwenhoven, FA
Glatz, JFC
Arends, JW
Citation: Hr. Hoogenboom et al., Selection-dominant and nonaccessible epitopes on cell-surface receptors revealed by cell-panning with a large phage antibody library, EUR J BIOCH, 260(3), 1999, pp. 774-784
Authors:
Klimka, A
Barth, S
Matthey, B
Roovers, RC
Lemke, H
Hansen, H
Arends, JW
Diehl, V
Hoogenboom, HR
Engert, A
Citation: A. Klimka et al., An anti-CD30 single-chain Fv selected by phage display and fused to Pseudomonas exotoxin A (Ki-4(scFV)-ETA ') is a potent immunotoxin against a Hodgkin-derived cell line, BR J CANC, 80(8), 1999, pp. 1214-1222