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Results: 1-17 |
Results: 17
Novel molecules that interact with microtubules and have functional activity similar to Taxol (TM)
Authors: He, LF Orr, GA Horwitz, SB
Citation: Lf. He et al., Novel molecules that interact with microtubules and have functional activity similar to Taxol (TM), DRUG DISC T, 6(22), 2001, pp. 1153-1164
Tumor targeting by covalent conjugation of a natural fatty acid to paclitaxel
Authors: Bradley, MO Webb, NL Anthony, FH Devanesan, P Witman, PA Hemamalini, S Chander, MC Baker, SD He, LF Horwitz, SB Swindell, CS
Citation: Mo. Bradley et al., Tumor targeting by covalent conjugation of a natural fatty acid to paclitaxel, CLIN CANC R, 7(10), 2001, pp. 3229-3238
The relationship between Taxol and (+)-discodermolide: synthetic analogs and modeling studies
Authors: Martello, LA LaMarche, MJ He, LF Beauchamp, TJ Smith, AB Horwitz, SB
Citation: La. Martello et al., The relationship between Taxol and (+)-discodermolide: synthetic analogs and modeling studies, CHEM BIOL, 8(9), 2001, pp. 843-855
The role of beta-tubulin isotypes in resistance to antimitotic drugs
Authors: Burkhart, CA Kavallaris, M Horwitz, SB
Citation: Ca. Burkhart et al., The role of beta-tubulin isotypes in resistance to antimitotic drugs, BBA-REV CAN, 1471(2), 2001, pp. O1-O9
Selective potentiation of paclitaxel (Taxol)-induced cell death by mitogen-activated protein kinase kinase inhibition in human cancer cell lines
Authors: McDaid, HM Horwitz, SB
Citation: Hm. Mcdaid et Sb. Horwitz, Selective potentiation of paclitaxel (Taxol)-induced cell death by mitogen-activated protein kinase kinase inhibition in human cancer cell lines, MOLEC PHARM, 60(2), 2001, pp. 290-301
The role of ERK 1/2 and p38 MAP-kinase pathways in Taxol-induced apoptosisin human ovarian carcinoma cells
Authors: Seidman, R Gitelman, I Sagi, O Horwitz, SB Wolfson, M
Citation: R. Seidman et al., The role of ERK 1/2 and p38 MAP-kinase pathways in Taxol-induced apoptosisin human ovarian carcinoma cells, EXP CELL RE, 268(1), 2001, pp. 84-92
Multiple microtubule alterations are associated with Vinca alkaloid resistance in human leukemia cells
Authors: Kavallaris, M Tait, AS Walsh, BJ He, LF Horwitz, SB Norris, MD Haber, M
Citation: M. Kavallaris et al., Multiple microtubule alterations are associated with Vinca alkaloid resistance in human leukemia cells, CANCER RES, 61(15), 2001, pp. 5803-5809
Identification by mass spectrometry of a new alpha-tubulin isotype expressed in human breast and lung carcinoma cell lines
Authors: Rao, S Aberg, F Nieves, E Horwitz, SB Orr, GA
Citation: S. Rao et al., Identification by mass spectrometry of a new alpha-tubulin isotype expressed in human breast and lung carcinoma cell lines, BIOCHEM, 40(7), 2001, pp. 2096-2103
On the total synthesis and preliminary biological evaluations of 15(R) and15(S) aza-dEpoB: A Mitsunobu inversion at C15 in pre-epothilone fragments
Authors: Stachel, SJ Chappell, MD Lee, CB Danishefsky, SJ Chou, TC He, LF Horwitz, SB
Citation: Sj. Stachel et al., On the total synthesis and preliminary biological evaluations of 15(R) and15(S) aza-dEpoB: A Mitsunobu inversion at C15 in pre-epothilone fragments, ORG LETT, 2(11), 2000, pp. 1637-1639
Taxol and discodermolide represent a synergistic drug combination in humancarcinoma cell lines
Authors: Martello, LA McDaid, HM Regl, DL Yang, CPH Meng, DF Pettus, TRR Kaufman, MD Arimoto, H Danishefsky, SJ Smith, AB Horwitz, SB
Citation: La. Martello et al., Taxol and discodermolide represent a synergistic drug combination in humancarcinoma cell lines, CLIN CANC R, 6(5), 2000, pp. 1978-1987
Taxol mediates serine phosphorylation of the 66-kDa Shc isoform
Authors: Yang, CPH Horwitz, SB
Citation: Cph. Yang et Sb. Horwitz, Taxol mediates serine phosphorylation of the 66-kDa Shc isoform, CANCER RES, 60(18), 2000, pp. 5171-5178
A common pharmacophore for Taxol and the epothilones based on the biological activity of a taxane molecule lacking a C-13 side chain
Authors: He, LF Jagtap, PGF Kingston, DGI Shen, HJ Orr, GA Horwitz, SB
Citation: Lf. He et al., A common pharmacophore for Taxol and the epothilones based on the biological activity of a taxane molecule lacking a C-13 side chain, BIOCHEM, 39(14), 2000, pp. 3972-3978
Structure activity profiles of eleutherobin analogs and their cross-resistance in Taxol-resistant cell lines
Authors: McDaid, HM Bhattacharya, SK Chen, XT He, LF Shen, HJ Gutteridge, CE Horwitz, SB Danishefsky, SJ
Citation: Hm. Mcdaid et al., Structure activity profiles of eleutherobin analogs and their cross-resistance in Taxol-resistant cell lines, CANC CHEMOT, 44(2), 1999, pp. 131-137
The synthesis and evaluation of 12,13-benzodesoxyepothilone B: a highly convergent route
Authors: Glunz, PW He, LF Horwitz, SB Chakravarty, S Ojima, I Chou, TC Danishefsky, SJ
Citation: Pw. Glunz et al., The synthesis and evaluation of 12,13-benzodesoxyepothilone B: a highly convergent route, TETRAHEDR L, 40(38), 1999, pp. 6895-6898
A common pharmacophore for cytotoxic natural products that stabilize microtubules
Authors: Ojima, I Chakravarty, S Inoue, T Lin, SN He, LF Horwitz, SB Kuduk, SD Danishefsky, SJ
Citation: I. Ojima et al., A common pharmacophore for cytotoxic natural products that stabilize microtubules, P NAS US, 96(8), 1999, pp. 4256-4261
Characterization of the taxol binding site on the microtubule - Identification of Arg(282) in beta-tubulin as the site of photoincorporation of a 7-benzophenone analogue of taxol
Authors: Rao, S He, LF Chakravarty, S Ojima, I Orr, GA Horwitz, SB
Citation: S. Rao et al., Characterization of the taxol binding site on the microtubule - Identification of Arg(282) in beta-tubulin as the site of photoincorporation of a 7-benzophenone analogue of taxol, J BIOL CHEM, 274(53), 1999, pp. 37990-37994
Antisense oligonucleotides to class III beta-tubulin sensitize drug-resistant cells to Taxol
Authors: Kavallaris, M Burkhart, CA Horwitz, SB
Citation: M. Kavallaris et al., Antisense oligonucleotides to class III beta-tubulin sensitize drug-resistant cells to Taxol, BR J CANC, 80(7), 1999, pp. 1020-1025
Risultati: 1-17 |