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Results: 1-25 |
Results: 25
Discriminative stimulus effects of the type-4 phosphodiesterase inhibitor rolipram in rats
Authors: Makhay, MM Houslay, MD O'Donnell, JM
Citation: Mm. Makhay et al., Discriminative stimulus effects of the type-4 phosphodiesterase inhibitor rolipram in rats, PSYCHOPHAR, 158(3), 2001, pp. 297-304
Identification of a surface on the beta-propeller protein RACK1 that interacts with the cAMP-specific phosphodiesterase PDE4D5
Authors: Steele, MR McCahill, A Thompson, DS MacKenzie, C Isaacs, NW Houslay, MD Bolger, GB
Citation: Mr. Steele et al., Identification of a surface on the beta-propeller protein RACK1 that interacts with the cAMP-specific phosphodiesterase PDE4D5, CELL SIGNAL, 13(7), 2001, pp. 507-513
The novel long PDE4A10 cyclic AMP phosphodiesterase shows a pattern of expression within brain that is distinct from the long PDE4A5 and short PDE4A1isoforms
Authors: McPhee, I Cochran, S Houslay, MD
Citation: I. Mcphee et al., The novel long PDE4A10 cyclic AMP phosphodiesterase shows a pattern of expression within brain that is distinct from the long PDE4A5 and short PDE4A1isoforms, CELL SIGNAL, 13(12), 2001, pp. 911-918
mAKAP assembles a protein kinase A/PDE4 phosphodiesterase cAMP signaling module
Authors: Dodge, KL Khouangsathiene, S Kapiloff, MS Mouton, R Hill, EV Houslay, MD Langeberg, LK Scott, JD
Citation: Kl. Dodge et al., mAKAP assembles a protein kinase A/PDE4 phosphodiesterase cAMP signaling module, EMBO J, 20(8), 2001, pp. 1921-1930
Development of rolipram-sensitive, cyclic AMP phosphodiesterase (PDE4) in rat primary neuronal cultures
Authors: Ye, Y Jackson, K Houslay, MD Chandler, LJ O'Donnell, JM
Citation: Y. Ye et al., Development of rolipram-sensitive, cyclic AMP phosphodiesterase (PDE4) in rat primary neuronal cultures, DEV BRAIN R, 130(1), 2001, pp. 115-121
PDE4 cAMP-specific phosphodiesterases
Authors: Houslay, MD
Citation: Md. Houslay, PDE4 cAMP-specific phosphodiesterases, PROG NUCL A, 69, 2001, pp. 249-315
Phorbol 12-myristate 13-acetate triggers the protein kinase A-mediated phosphorylation and activation of the PDE4D5 cAMP phosphodiesterase in human aortic smooth muscle cells through a route involving extracellular signal regulated kinase (ERK)
Authors: Baillie, G MacKenzie, SJ Houslay, MD
Citation: G. Baillie et al., Phorbol 12-myristate 13-acetate triggers the protein kinase A-mediated phosphorylation and activation of the PDE4D5 cAMP phosphodiesterase in human aortic smooth muscle cells through a route involving extracellular signal regulated kinase (ERK), MOLEC PHARM, 60(5), 2001, pp. 1100-1111
Molecular cloning, genomic positioning, promoter identification, and characterization of the novel cyclic AMP-specific phosphodiesterase PDE4A10
Authors: Rena, G Begg, F Ross, A Mackenzie, C Mcphee, I Campbell, L Huston, E Sullivan, M Houslay, MD
Citation: G. Rena et al., Molecular cloning, genomic positioning, promoter identification, and characterization of the novel cyclic AMP-specific phosphodiesterase PDE4A10, MOLEC PHARM, 59(5), 2001, pp. 996-1011
Adenosine 3 ',5 '-cyclic monophosphate (cAMP)-dependent inhibition of IL-5from human T lymphocytes is not mediated by the cAMP-dependent protein kinase A(1)
Authors: Staples, KJ Bergmann, M Tomita, K Houslay, MD McPhee, I Barnes, PJ Giembycz, MA Newton, R
Citation: Kj. Staples et al., Adenosine 3 ',5 '-cyclic monophosphate (cAMP)-dependent inhibition of IL-5from human T lymphocytes is not mediated by the cAMP-dependent protein kinase A(1), J IMMUNOL, 167(4), 2001, pp. 2074-2080
The RACK1 signaling scaffold protein selectively interacts with the cAMP-specific phosphodiesterase PDE4D5 isoform (vol 274, pg 14909, 1999)
Authors: Yarwood, SJ Steele, MR Scotland, G Houslay, MD Bolger, GB
Citation: Sj. Yarwood et al., The RACK1 signaling scaffold protein selectively interacts with the cAMP-specific phosphodiesterase PDE4D5 isoform (vol 274, pg 14909, 1999), J BIOL CHEM, 276(9), 2001, pp. 6879-6879
Surgically induced cryptorchidism-related degenerative changes in spermatogonia are associated with loss of cyclic adenosine monophosphate-dependent phosphodiesterases type 4 in abdominal testes of rats
Authors: Faroqui, SM Al-Bagdadi, F Houslay, MD Bolger, GB Stout, R Specian, RD Cherry, JA Conti, M O'Donnell, JM
Citation: Sm. Faroqui et al., Surgically induced cryptorchidism-related degenerative changes in spermatogonia are associated with loss of cyclic adenosine monophosphate-dependent phosphodiesterases type 4 in abdominal testes of rats, BIOL REPROD, 64(6), 2001, pp. 1583-1589
Action of rolipram on specific PDE4 cAMP phosphodiesterase isoforms and onthe phosphorylation of cAMP-response-element-binding protein (CREB) and p38 mitogen-activated protein (MAP) kinase in U937 monocytic cells
Authors: MacKenzie, SJ Houslay, MD
Citation: Sj. Mackenzie et Md. Houslay, Action of rolipram on specific PDE4 cAMP phosphodiesterase isoforms and onthe phosphorylation of cAMP-response-element-binding protein (CREB) and p38 mitogen-activated protein (MAP) kinase in U937 monocytic cells, BIOCHEM J, 347, 2000, pp. 571-578
Cell-type specific integration of cross-talk between extracellular signal-regulated kinase and cAMP signaling
Authors: Houslay, MD Kolch, W
Citation: Md. Houslay et W. Kolch, Cell-type specific integration of cross-talk between extracellular signal-regulated kinase and cAMP signaling, MOLEC PHARM, 58(4), 2000, pp. 659-668
Membrane localization of cyclic nucleotide phosphodiesterase 3 (PDES) - Two N-terminal, domains are required for the efficient targeting to, and association of, PDE3 with endoplasmic reticulum
Authors: Shakur, Y Takeda, K Kenan, Y Yu, ZX Rena, G Brandt, D Houslay, MD Degerman, E Ferrans, VJ Manganiello, VC
Citation: Y. Shakur et al., Membrane localization of cyclic nucleotide phosphodiesterase 3 (PDES) - Two N-terminal, domains are required for the efficient targeting to, and association of, PDE3 with endoplasmic reticulum, J BIOL CHEM, 275(49), 2000, pp. 38749-38761
The cAMP-specific phosphodiesterase PDE4A5 is cleaved downstream of its SH3 interaction domain by caspase-3 - Consequences for altered intracellular distribution
Authors: Huston, E Beard, M McCallum, F Pyne, NJ Vandenabeele, P Scotland, G Houslay, MD
Citation: E. Huston et al., The cAMP-specific phosphodiesterase PDE4A5 is cleaved downstream of its SH3 interaction domain by caspase-3 - Consequences for altered intracellular distribution, J BIOL CHEM, 275(36), 2000, pp. 28063-28074
ERK2 mitogen-activated protein kinase binding, phosphorylation, and regulation of the PDE4D cAMP-specific phosphodiesterases - The involvement of COOH-terminal docking sites and NH2-terminal UCR regions
Authors: MacKenzie, SJ Baillie, GS McPhee, I Bolger, GB Houslay, MD
Citation: Sj. Mackenzie et al., ERK2 mitogen-activated protein kinase binding, phosphorylation, and regulation of the PDE4D cAMP-specific phosphodiesterases - The involvement of COOH-terminal docking sites and NH2-terminal UCR regions, J BIOL CHEM, 275(22), 2000, pp. 16609-16617
UCR1 and UCR2 domains unique to the cAMP-specific phosphodiesterase familyform a discrete module via electrostatic interactions
Authors: Beard, MB Olsen, AE Jones, RE Erdogan, S Houslay, MD Bolger, GB
Citation: Mb. Beard et al., UCR1 and UCR2 domains unique to the cAMP-specific phosphodiesterase familyform a discrete module via electrostatic interactions, J BIOL CHEM, 275(14), 2000, pp. 10349-10358
Use of an activation-specific probe to show that Rap1A and Rap1B display different sensitivities to activation by forskolin in Rat1 cells
Authors: McPhee, I Houslay, MD Yarwood, SJ
Citation: I. Mcphee et al., Use of an activation-specific probe to show that Rap1A and Rap1B display different sensitivities to activation by forskolin in Rat1 cells, FEBS LETTER, 477(3), 2000, pp. 213-218
Sub-family selective actions in the ability of Erk2 MAP kinase to phosphorylate and regulate the activity of PDE4 cyclic AMP-specific phosphodiesterases
Authors: Baillie, GS MacKenzie, SJ McPhee, I Houslay, MD
Citation: Gs. Baillie et al., Sub-family selective actions in the ability of Erk2 MAP kinase to phosphorylate and regulate the activity of PDE4 cyclic AMP-specific phosphodiesterases, BR J PHARM, 131(4), 2000, pp. 811-819
Genomic organisation of the human cyclic AMP-specific phosphodiesterase PDE4C gene and its chromosomal localisation to 19p13.1, between RAB3A and JUND
Authors: Sullivan, M Olsen, AS Houslay, MD
Citation: M. Sullivan et al., Genomic organisation of the human cyclic AMP-specific phosphodiesterase PDE4C gene and its chromosomal localisation to 19p13.1, between RAB3A and JUND, CELL SIGNAL, 11(10), 1999, pp. 735-742
The MAP kinase ERK2 inhibits the cyclic AMP-specific phosphodiesterase HSPDE4D3 by phosphorylating it at Ser579
Authors: Hoffmann, R Baillie, GS MacKenzie, SJ Yarwood, SJ Houslay, MD
Citation: R. Hoffmann et al., The MAP kinase ERK2 inhibits the cyclic AMP-specific phosphodiesterase HSPDE4D3 by phosphorylating it at Ser579, EMBO J, 18(4), 1999, pp. 893-903
The RACK1 signaling scaffold protein selectively interacts with the cAMP-specific phosphodiesterase PDE4D5 isoform
Authors: Yarwood, SJ Steele, MR Scotland, G Houslay, MD Bolger, GB
Citation: Sj. Yarwood et al., The RACK1 signaling scaffold protein selectively interacts with the cAMP-specific phosphodiesterase PDE4D5 isoform, J BIOL CHEM, 274(21), 1999, pp. 14909-14917
Association with the SRC family tyrosyl kinase LYN triggers a conformational change in the catalytic region of human cAMP-specific phosphodiesterase HSPDE4A4B - Consequences for rolipram inhibition
Authors: McPhee, I Yarwood, SJ Scotland, G Huston, E Beard, MB Ross, AH Houslay, ES Houslay, MD
Citation: I. Mcphee et al., Association with the SRC family tyrosyl kinase LYN triggers a conformational change in the catalytic region of human cAMP-specific phosphodiesterase HSPDE4A4B - Consequences for rolipram inhibition, J BIOL CHEM, 274(17), 1999, pp. 11796-11810
Growth hormone-dependent differentiation of 3T3-F442A preadipocytes requires Janus kinase signal transducer and activator of transcription but not mitogen-activated protein kinase or p70 S6 kinase signaling
Authors: Yarwood, SJ Sale, EM Sale, GJ Houslay, MD Kilgour, E Anderson, NG
Citation: Sj. Yarwood et al., Growth hormone-dependent differentiation of 3T3-F442A preadipocytes requires Janus kinase signal transducer and activator of transcription but not mitogen-activated protein kinase or p70 S6 kinase signaling, J BIOL CHEM, 274(13), 1999, pp. 8662-8668
The unique N-terminal domain of the cAMP phosphodiesterase PDE4D4 allows for interaction with specific SH3 domains
Authors: Beard, MB O'Connell, JC Bolger, GB Houslay, MD
Citation: Mb. Beard et al., The unique N-terminal domain of the cAMP phosphodiesterase PDE4D4 allows for interaction with specific SH3 domains, FEBS LETTER, 460(1), 1999, pp. 173-177
Risultati: 1-25 |