Authors:
Kenworthy, KE
Clarke, SE
Andrews, J
Houston, JB
Citation: Ke. Kenworthy et al., Multisite kinetic models for CYP3A4: Simultaneous activation and inhibition of diazepam and testosterone metabolism, DRUG META D, 29(12), 2001, pp. 1644-1651
Citation: Jb. Houston et Ke. Kenworthy, In vitro-in vivo scaling of CYP kinetic data not consistent with the classical Michaelis-Menten model, DRUG META D, 28(3), 2000, pp. 246-254
Authors:
DeJongh, J
Forsby, A
Houston, JB
Beckman, M
Combes, R
Blaauboer, BJ
Citation: J. Dejongh et al., An integrated approach to the prediction of systemic toxicity using computer-based biokinetic models and biological in vitro test methods: Overview of a prevalidation study based on the ECITTS project (vol 13, pg 549, 1999), TOX VITRO, 13(6), 1999, pp. 939-939
Authors:
DeJongh, J
Forsby, A
Houston, JB
Beckman, M
Combes, R
Blaauboer, BJ
Citation: J. Dejongh et al., An integrated approach to the prediction of systemic toxicity using computer-based biokinetic models and biological in vitro test methods: Overview of a prevalidation study based on the ECITTS project, TOX VITRO, 13(4-5), 1999, pp. 549-554
Citation: Bj. Blaauboer et al., The integrated use of alternative methods in toxicological risk evaluation- ECVAM Integrated Testing Strategies task force report 1, ATLA-ALT L, 27(2), 1999, pp. 229-237
Citation: Dj. Carlile et al., Kinetics of drug metabolism in rat liver slices: IV. Comparison of ethoxycoumarin clearance by liver slices, isolated hepatocytes, and hepatic microsomes from rats pretreated with known modifiers of cytochrome P-450 activity, DRUG META D, 27(4), 1999, pp. 526-532
Citation: Le. Witherow et Jb. Houston, Sigmoidal kinetics of CYP3A substrates: An approach for scaling dextromethorphan metabolism in hepatic microsomes and isolated hepatocytes to predictin vivo clearance in rat, J PHARM EXP, 290(1), 1999, pp. 58-65