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Results: 1-11 |
Results: 11
Neurodegenerative changes associated with beta-amyloid deposition in the brains of mice carrying mutant amyloid precursor protein and mutant presenilin-1 transgenes
Authors: Kurt, MA Davies, DC Kidd, M Duff, K Rolph, SC Jennings, KH Howlett, DR
Citation: Ma. Kurt et al., Neurodegenerative changes associated with beta-amyloid deposition in the brains of mice carrying mutant amyloid precursor protein and mutant presenilin-1 transgenes, EXP NEUROL, 171(1), 2001, pp. 59-71
Association of JNK immunoreactivity with B-amyloid/tau deposits in transgenic mouse brain
Authors: Howlett, DR
Citation: Dr. Howlett, Association of JNK immunoreactivity with B-amyloid/tau deposits in transgenic mouse brain, ALZHEIM REP, 3(1), 2000, pp. 11-14
ASP1 (BACE2) cleaves the amyloid precursor protein at the beta-secretase site
Authors: Hussain, I Powell, DJ Howlett, DR Chapman, GA Gilmour, L Murdock, PR Tew, DG Meek, TD Chapman, C Schneider, K Ratcliffe, SJ Tattersall, D Testa, TT Southan, C Ryan, DM Simmons, DL Walsh, FS Dingwall, C Christie, G
Citation: I. Hussain et al., ASP1 (BACE2) cleaves the amyloid precursor protein at the beta-secretase site, MOL CELL NE, 16(5), 2000, pp. 609-619
Fractionation and characterization of oligomeric, protofibrillar and fibrillar forms of beta-amyloid peptide
Authors: Ward, RV Jennings, KH Jepras, R Neville, W Owen, DE Hawkins, J Christie, G Davis, JB George, A Karran, EH Howlett, DR
Citation: Rv. Ward et al., Fractionation and characterization of oligomeric, protofibrillar and fibrillar forms of beta-amyloid peptide, BIOCHEM J, 348, 2000, pp. 137-144
In search of an enzyme: the beta-secretase of Alzheimer's disease is an aspartic proteinase
Authors: Howlett, DR Simmons, DL Dingwall, C Christie, G
Citation: Dr. Howlett et al., In search of an enzyme: the beta-secretase of Alzheimer's disease is an aspartic proteinase, TRENDS NEUR, 23(11), 2000, pp. 565-570
Biological activity associated with a high molecular weight form of beta-amyloid
Authors: Howlett, DR Ward, RV Bresciani, L Jennings, KH Christie, G Allsop, D Gray, CW Karran, EH
Citation: Dr. Howlett et al., Biological activity associated with a high molecular weight form of beta-amyloid, ALZHEIM REP, 2(3), 1999, pp. 171-177
Identification of a novel aspartic protease (Asp 2) as beta-secretase
Authors: Hussain, I Powell, D Howlett, DR Tew, DG Week, TD Chapman, C Gloger, IS Murphy, KE Southan, CD Ryan, DM Smith, TS Simmons, DL Walsh, FS Dingwall, C Christie, G
Citation: I. Hussain et al., Identification of a novel aspartic protease (Asp 2) as beta-secretase, MOL CELL NE, 14(6), 1999, pp. 419-427
Common structural features determine the effectiveness of carvedilol, daunomycin and rolitetracycline as inhibitors of Alzheimer beta-amyloid fibril formation
Authors: Howlett, DR George, AR Owen, DE Ward, RV Markwell, RE
Citation: Dr. Howlett et al., Common structural features determine the effectiveness of carvedilol, daunomycin and rolitetracycline as inhibitors of Alzheimer beta-amyloid fibril formation, BIOCHEM J, 343, 1999, pp. 419-423
Inhibition of fibril formation in beta-amyloid peptide by a novel series of benzofurans
Authors: Howlett, DR Perry, AE Godfrey, F Swatton, JE Jennings, KH Spitzfaden, C Wadsworth, H Wood, SJ Markwell, RE
Citation: Dr. Howlett et al., Inhibition of fibril formation in beta-amyloid peptide by a novel series of benzofurans, BIOCHEM J, 340, 1999, pp. 283-289
Alzheimer's disease: Correlation of the suppression of beta-amyloid peptide secretion from cultured cells with inhibition of the chymotrypsin-like activity of the proteasome
Authors: Christie, G Markwell, RE Gray, CW Smith, L Godfrey, F Mansfield, F Wadsworth, H King, R McLaughlin, M Cooper, DG Ward, RV Howlett, DR Hartmann, T Lichtenthaler, SF Beyreuther, K Underwood, J Gribble, SK Cappai, R Masters, CL Tamaoka, A Gardner, RL Rivett, AJ Karran, EH Allsop, D
Citation: G. Christie et al., Alzheimer's disease: Correlation of the suppression of beta-amyloid peptide secretion from cultured cells with inhibition of the chymotrypsin-like activity of the proteasome, J NEUROCHEM, 73(1), 1999, pp. 195-204
Computationally derived structural models of the beta-amyloid found in Alzheimer's disease plaques and the interaction with possible aggregation inhibitors
Authors: George, AR Howlett, DR
Citation: Ar. George et Dr. Howlett, Computationally derived structural models of the beta-amyloid found in Alzheimer's disease plaques and the interaction with possible aggregation inhibitors, BIOPOLYMERS, 50(7), 1999, pp. 733-741
Risultati: 1-11 |