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Results: 1-25 | 26-48
Results: 1-25/48
REGULATION OF PROSTAGLANDIN BIOSYNTHESIS IN-VIVO BY GLUTATHIONE
Authors: MARGALIT A HAUSER SD ZWEIFEL BS ANDERSON MA ISAKSON PC
Citation: A. Margalit et al., REGULATION OF PROSTAGLANDIN BIOSYNTHESIS IN-VIVO BY GLUTATHIONE, American journal of physiology. Regulatory, integrative and comparative physiology, 43(2), 1998, pp. 294-302
PHARMACOLOGICAL ANALYSIS OF CYCLOOXYGENASE-1 IN INFLAMMATION
Authors: SMITH CJ ZHANG Y KOBOLDT CM MUHAMMAD J ZWEIFEL BS SHAFFER A TALLEY JJ MASFERRER JL SEIBERT K ISAKSON PC
Citation: Cj. Smith et al., PHARMACOLOGICAL ANALYSIS OF CYCLOOXYGENASE-1 IN INFLAMMATION, Proceedings of the National Academy of Sciences of the United Statesof America, 95(22), 1998, pp. 13313-13318
CYCLOOXYGENASE-2 INHIBITION PREVENTS DELAYED DEATH OF CA1 HIPPOCAMPAL-NEURONS FOLLOWING GLOBAL-ISCHEMIA
Authors: NAKAYAMA M UCHIMURA K ZHU RL NAGAYAMA T ROSE ME STETLER RA ISAKSON PC CHEN J GRAHAM SH
Citation: M. Nakayama et al., CYCLOOXYGENASE-2 INHIBITION PREVENTS DELAYED DEATH OF CA1 HIPPOCAMPAL-NEURONS FOLLOWING GLOBAL-ISCHEMIA, Proceedings of the National Academy of Sciences of the United Statesof America, 95(18), 1998, pp. 10954-10959
EFFECT OF COX-1 AND COX-2 INHIBITION ON INDUCTION AND MAINTENANCE OF CARRAGEENAN-EVOKED THERMAL HYPERALGESIA IN RATS
Authors: DIRIG DM ISAKSON PC YAKSH TL
Citation: Dm. Dirig et al., EFFECT OF COX-1 AND COX-2 INHIBITION ON INDUCTION AND MAINTENANCE OF CARRAGEENAN-EVOKED THERMAL HYPERALGESIA IN RATS, The Journal of pharmacology and experimental therapeutics, 285(3), 1998, pp. 1031-1038
PRELIMINARY-STUDY OF THE SAFETY AND EFFICACY OF SC-58635, A NOVEL CYCLOOXYGENASE-2 INHIBITOR - EFFICACY AND SAFETY IN 2 PLACEBO-CONTROLLED TRIALS IN OSTEOARTHRITIS AND RHEUMATOID-ARTHRITIS, AND STUDIES OF GASTROINTESTINAL AND PLATELET EFFECTS
Authors: SIMON LS LANZA FL LIPSKY PE HUBBARD RC TALWALKER S SCHWARTZ BD ISAKSON PC GEIS GS
Citation: Ls. Simon et al., PRELIMINARY-STUDY OF THE SAFETY AND EFFICACY OF SC-58635, A NOVEL CYCLOOXYGENASE-2 INHIBITOR - EFFICACY AND SAFETY IN 2 PLACEBO-CONTROLLED TRIALS IN OSTEOARTHRITIS AND RHEUMATOID-ARTHRITIS, AND STUDIES OF GASTROINTESTINAL AND PLATELET EFFECTS, Arthritis and rheumatism, 41(9), 1998, pp. 1591-1602
3,4-DIARYLPYRAZOLES - POTENT AND SELECTIVE INHIBITORS OF CYCLOOXYGENASE-2
Authors: PENNING TD KRAMER SW LEE LF COLLINS PW KOBOLDT CM SEIBERT K VEENHUIZEN AW ZHANG YY ISAKSON PC
Citation: Td. Penning et al., 3,4-DIARYLPYRAZOLES - POTENT AND SELECTIVE INHIBITORS OF CYCLOOXYGENASE-2, Bioorganic & medicinal chemistry letters, 7(16), 1997, pp. 2121-2124
CYCLOOXYGENASE-2 EXPRESSION DURING RAT NEOCORTICAL DEVELOPMENT AND INRETT-SYNDROME
Authors: KAUFMANN WE WORLEY PF TAYLOR CV BREMER M ISAKSON PC
Citation: We. Kaufmann et al., CYCLOOXYGENASE-2 EXPRESSION DURING RAT NEOCORTICAL DEVELOPMENT AND INRETT-SYNDROME, Brain & development, 19(1), 1997, pp. 25-34
ALTERED ARACHIDONIC-ACID METABOLISM IN URATE CRYSTAL-INDUCED INFLAMMATION
Authors: MARGALIT A DUFFIN KL SHAFFER AF GREGORY SA ISAKSON PC
Citation: A. Margalit et al., ALTERED ARACHIDONIC-ACID METABOLISM IN URATE CRYSTAL-INDUCED INFLAMMATION, Inflammation, 21(2), 1997, pp. 205-222
THE DISCOVERY AND FUNCTION OF COX-2
Authors: NEEDLEMAN P ISAKSON PC
Citation: P. Needleman et Pc. Isakson, THE DISCOVERY AND FUNCTION OF COX-2, Journal of rheumatology, 24, 1997, pp. 6-8
OUTCOME OF SPECIFIC COX-2 INHIBITION IN RHEUMATOID-ARTHRITIS
Authors: LIPSKY PE ISAKSON PC
Citation: Pe. Lipsky et Pc. Isakson, OUTCOME OF SPECIFIC COX-2 INHIBITION IN RHEUMATOID-ARTHRITIS, Journal of rheumatology, 24, 1997, pp. 9-14
CYCLOOXYGENASES AND THE CENTRAL-NERVOUS-SYSTEM
Authors: KAUFMANN WE ANDREASSON KL ISAKSON PC WORLEY PF
Citation: We. Kaufmann et al., CYCLOOXYGENASES AND THE CENTRAL-NERVOUS-SYSTEM, Prostaglandins, 54(3), 1997, pp. 601-624
STRUCTURAL BASIS FOR SELECTIVE-INHIBITION OF CYCLOOXYGENASE-2 BY ANTIINFLAMMATORY AGENTS (VOL 384, PG 644, 1996)
Authors: KURUMBAIL RG STEVENS AM GIERSE JK MCDONALD JJ STEGEMAN RA PAK JY GILDEHAUS D MIYASHIRO JM PENNING TD SEIBERT K ISAKSON PC STALLINGS WC
Citation: Rg. Kurumbail et al., STRUCTURAL BASIS FOR SELECTIVE-INHIBITION OF CYCLOOXYGENASE-2 BY ANTIINFLAMMATORY AGENTS (VOL 384, PG 644, 1996), Nature, 385(6616), 1997, pp. 555-555
INHIBITION OF CYCLOOXYGENASE-2 RAPIDLY REVERSES INFLAMMATORY HYPERALGESIA AND PROSTAGLANDIN E-2 PRODUCTION
Authors: ZHANG Y SHAFFER A PORTANOVA J SEIBERT K ISAKSON PC
Citation: Y. Zhang et al., INHIBITION OF CYCLOOXYGENASE-2 RAPIDLY REVERSES INFLAMMATORY HYPERALGESIA AND PROSTAGLANDIN E-2 PRODUCTION, The Journal of pharmacology and experimental therapeutics, 283(3), 1997, pp. 1069-1075
SYNTHESIS AND BIOLOGICAL EVALUATION OF THE 1,5-DIARYLPYRAZOLE CLASS OF CYCLOOXYGENASE-2 INHIBITORS - IDENTIFICATION OF RIFLUOROMETHYL)-1H-PYRAZOL-1-YL]BENZENESULFONAMIDE (SC-58635, CELECOXIB)
Authors: PENNING TD TALLEY JJ BERTENSHAW SR CARTER JS COLLINS PW DOCTER S GRANETO MJ LEE LF MALECHA JW MIYASHIRO JM ROGERS RS ROGIER DJ YU SS ANDERSON GD BURTON EG COGBURN JN GREGORY SA KOBOLDT CM PERKINS WE SEIBERT K VEENHUIZEN AW ZHANG YY ISAKSON PC
Citation: Td. Penning et al., SYNTHESIS AND BIOLOGICAL EVALUATION OF THE 1,5-DIARYLPYRAZOLE CLASS OF CYCLOOXYGENASE-2 INHIBITORS - IDENTIFICATION OF RIFLUOROMETHYL)-1H-PYRAZOL-1-YL]BENZENESULFONAMIDE (SC-58635, CELECOXIB), Journal of medicinal chemistry, 40(9), 1997, pp. 1347-1365
1,2-DIARYLPYRROLES AS POTENT AND SELECTIVE INHIBITORS OF CYCLOOXYGENASE-2
Authors: KHANNA IK WEIER RM YU Y COLLINS PW MIYASHIRO JM KOBOLDT CM VEENHUIZEN AW CURRIE JL SEIBERT K ISAKSON PC
Citation: Ik. Khanna et al., 1,2-DIARYLPYRROLES AS POTENT AND SELECTIVE INHIBITORS OF CYCLOOXYGENASE-2, Journal of medicinal chemistry, 40(11), 1997, pp. 1619-1633
1,2-DIARYLIMIDAZOLES AS POTENT, CYCLOOXYGENASE-2 SELECTIVE, AND ORALLY-ACTIVE ANTIINFLAMMATORY AGENTS
Authors: KHANNA IK WEIER RM YU Y XU XD KOSZYK FJ COLLINS PW KOBOLDT CM VEENHUIZEN AW PERKINS WE CASLER JJ MASFERRER JL ZHANG YY GREGORY SA SEIBERT K ISAKSON PC
Citation: Ik. Khanna et al., 1,2-DIARYLIMIDAZOLES AS POTENT, CYCLOOXYGENASE-2 SELECTIVE, AND ORALLY-ACTIVE ANTIINFLAMMATORY AGENTS, Journal of medicinal chemistry, 40(11), 1997, pp. 1634-1647
A SELECTIVE CYCLOOXYGENASE-2 INHIBITOR SUPPRESSES THE GROWTH OF H-RAS-TRANSFORMED RAT INTESTINAL EPITHELIAL-CELLS
Authors: SHENG GG SHAO JY SHENG HM HOOTON EB ISAKSON PC MORROW JD COFFEY RJ DUBOIS RN BEAUCHAMP RD
Citation: Gg. Sheng et al., A SELECTIVE CYCLOOXYGENASE-2 INHIBITOR SUPPRESSES THE GROWTH OF H-RAS-TRANSFORMED RAT INTESTINAL EPITHELIAL-CELLS, Gastroenterology, 113(6), 1997, pp. 1883-1891
CHRONIC TGF-BETA TREATMENT CAUSES MALIGNANT TRANSFORMATION OF RAT INTESTINAL EPITHELIAL-CELLS (RIE-1) ASSOCIATED WITH OVEREXPRESSION OF CYCLOOXYGENASE-2
Authors: SHENG H SHAO J HOOTON EB LAMPS L ISAKSON PC MORROW JD DUBOIS RN BEAUCHAMP RD
Citation: H. Sheng et al., CHRONIC TGF-BETA TREATMENT CAUSES MALIGNANT TRANSFORMATION OF RAT INTESTINAL EPITHELIAL-CELLS (RIE-1) ASSOCIATED WITH OVEREXPRESSION OF CYCLOOXYGENASE-2, Gastroenterology, 112(4), 1997, pp. 654-654
A SELECTIVE CYCLOOXYGENASE-2 INHIBITOR (SC-58125) SUPPRESSES THE GROWTH OF H-RAS-TRANSFORMED RAT INTESTINAL EPITHELIAL-CELLS
Authors: SHENG GG SHAO J SHENG H HOOTON EB ISAKSON PC MORROW JD COFFEY RJ DUBOIS RN BEAUCHAMP RD
Citation: Gg. Sheng et al., A SELECTIVE CYCLOOXYGENASE-2 INHIBITOR (SC-58125) SUPPRESSES THE GROWTH OF H-RAS-TRANSFORMED RAT INTESTINAL EPITHELIAL-CELLS, Gastroenterology, 112(4), 1997, pp. 654-654
EFFECT OF SPINAL CYCLOOXYGENASE INHIBITORS IN RAT USING THE FORMALIN TEST AND IN-VITRO PROSTAGLANDIN E-2 RELEASE
Authors: DIRIG DM KONIN GP ISAKSON PC YAKSH TL
Citation: Dm. Dirig et al., EFFECT OF SPINAL CYCLOOXYGENASE INHIBITORS IN RAT USING THE FORMALIN TEST AND IN-VITRO PROSTAGLANDIN E-2 RELEASE, European journal of pharmacology, 331(2-3), 1997, pp. 155-160
A STUDY OF THE PLATELET EFFECTS OF SC-58635, A NOVEL COX-2-SELECTIVE INHIBITOR
Authors: MENGLEGAW L HUBBARD RC KARIM A YU SS TALWALKER S ISAKSON PC GEIS GS SCHWARTZ BD
Citation: L. Menglegaw et al., A STUDY OF THE PLATELET EFFECTS OF SC-58635, A NOVEL COX-2-SELECTIVE INHIBITOR, Arthritis and rheumatism, 40(9), 1997, pp. 374-374
SPINAL AND SYSTEMIC CYCLOOXYGENASE (COX) INHIBITORS SUPPRESS PAW CARRAGEENAN-EVOKED THERMAL HYPERALGESIA IN RATS
Authors: DIRIG DM ISAKSON PC YAKSH TL
Citation: Dm. Dirig et al., SPINAL AND SYSTEMIC CYCLOOXYGENASE (COX) INHIBITORS SUPPRESS PAW CARRAGEENAN-EVOKED THERMAL HYPERALGESIA IN RATS, Anesthesiology, 87(3), 1997, pp. 721-721
SC-58635, A HIGHLY SELECTIVE INHIBITOR OF COX-2, IS AN EFFECTIVE ANALGESIC IN AN ACUTE POSTSURGICAL PAIN MODEL
Authors: HUBBARD RC MEHLISCH DR JASPER DR NUGENT MJ YU S ISAKSON PC
Citation: Rc. Hubbard et al., SC-58635, A HIGHLY SELECTIVE INHIBITOR OF COX-2, IS AN EFFECTIVE ANALGESIC IN AN ACUTE POSTSURGICAL PAIN MODEL, Journal of investigative medicine, 44(3), 1996, pp. 293-293
CYCLOOXYGENASE-2 INHIBITORS - A NEW CLASS OF ANTIINFLAMMATORY AGENTS THAT SPARE THE GASTROINTESTINAL-TRACT
Authors: MASFERRER JL ISAKSON PC SEIBERT K
Citation: Jl. Masferrer et al., CYCLOOXYGENASE-2 INHIBITORS - A NEW CLASS OF ANTIINFLAMMATORY AGENTS THAT SPARE THE GASTROINTESTINAL-TRACT, Gastroenterology clinics of North America, 25(2), 1996, pp. 363
STRUCTURAL BASIS FOR SELECTIVE-INHIBITION OF CYCLOOXYGENASE-2 BY ANTIINFLAMMATORY AGENTS
Authors: KURUMBAIL RG STEVENS AM GIERSE JK MCDONALD JJ STEGEMAN RA PAK JY GILDEHAUS D MIYASHIRO JM PENNING TD SEIBERT K ISAKSON PC STALLINGS WC
Citation: Rg. Kurumbail et al., STRUCTURAL BASIS FOR SELECTIVE-INHIBITION OF CYCLOOXYGENASE-2 BY ANTIINFLAMMATORY AGENTS, Nature, 384(6610), 1996, pp. 644-648
Risultati: 1-25 | 26-48