Citation: J. Iley et al., Chemical and microsomal oxidation of tertiary amides: regio- and stereoselective aspects, J CHEM S P2, (8), 2001, pp. 1299-1305
Citation: J. Iley et al., Chemical and microsomal oxidation of tertiary amides: regio- and stereoselective aspects (vol 11, pg 1299, 2001), J CHEM S P2, (11), 2001, pp. 2233-2233
Authors:
Clemente, A
Domingos, A
Grancho, AP
Iley, J
Moreira, R
Neres, J
Palma, N
Santana, AB
Valente, E
Citation: A. Clemente et al., Design, synthesis and stability of N-acyloxymethyl- and N-aminocarbonyloxymethyl-2-azetidinones as human leukocyte elastase inhibitors, BIOORG MED, 11(8), 2001, pp. 1065-1068
Authors:
Iley, J
Barroso, H
Moreira, R
Lopes, F
Calheiros, T
Citation: J. Iley et al., Acyloxymethyl as a drug protecting group. Part 7: Tertiary sulfonamidomethyl ester prodrugs of benzylpenicillin: Chemical hydrolysis and anti-bacterial activity, BIO MED CH, 8(7), 2000, pp. 1629-1636
Authors:
Carvalho, E
Francisco, AP
Iley, J
Rosa, E
Citation: E. Carvalho et al., Triazene drug metabolites. Part 17: Synthesis and plasma hydrolysis of acyloxymethyl carbamate derivatives of antitumour triazenes, BIO MED CH, 8(7), 2000, pp. 1719-1725
Citation: F. Lopes et al., Acyloxymethyl as a drug protecting group. Part 6: N-acyloxymethyl- and N-[(aminocarbonyloxy)methyl]sulfonamides as prodrugs of agents containing a secondary sulfonamide group, BIO MED CH, 8(4), 2000, pp. 707-716
Authors:
Constantino, L
Paixao, P
Moreira, R
Portela, MJ
Do Rosario, VE
Iley, J
Citation: L. Constantino et al., Metabolism of primaquine by liver homogenate fractions - Evidence for monoamine oxidase and cytochrome P450 involvement in the oxidative deamination of primaquine to carboxyprimaquine, EXP TOX PAT, 51(4-5), 1999, pp. 299-303
Citation: J. Iley et al., Cleavage of tertiary amidomethyl ester prodrugs of carboxylic acids by ratliver homogenates, EUR J PH SC, 9(2), 1999, pp. 201-205
Authors:
Portela, MJ
Moreira, R
Valente, E
Constantino, L
Iley, J
Pinto, J
Rosa, R
Cravo, P
do Rosario, VE
Citation: Mj. Portela et al., Dipeptide derivatives of primaquine as transmission-blocking antimalarials: Effect of aliphatic side-chain acylation on the gametocytocidal activity and on the formation of carboxyprimaquine in rat liver homogenates, PHARM RES, 16(6), 1999, pp. 949-955
Citation: F. Lopes et al., Acyloxymethyl as a drug protecting group. Part 5. Kinetics and mechanism of the hydrolysis of tertiary N-acyloxymethylsulfonamides, J CHEM S P2, (3), 1999, pp. 431-439
Citation: L. Constantino et J. Iley, Microsomal metabolism of N,N-diethyl-m-toluamide (DEET, DET): the extendednetwork of metabolites, XENOBIOTICA, 29(4), 1999, pp. 409-416