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Results: 1-25 |
Results: 25
EFFECTS OF BETA-3-INTEGRIN BLOCKADE (C7E3) ON THE RESPONSE TO ANGIOPLASTY AND INTRAARTERIAL STENTING IN ATHEROSCLEROTIC NONHUMAN-PRIMATES
Authors: DEITCH JS WILLIAMS JK ADAMS MR FLY CA HERRINGTON DM JORDAN RE NAKADA MT JAKUBOWSKI JA GEARY RL
Citation: Js. Deitch et al., EFFECTS OF BETA-3-INTEGRIN BLOCKADE (C7E3) ON THE RESPONSE TO ANGIOPLASTY AND INTRAARTERIAL STENTING IN ATHEROSCLEROTIC NONHUMAN-PRIMATES, Arteriosclerosis, thrombosis, and vascular biology, 18(11), 1998, pp. 1730-1737
DEVELOPMENT OF DUAL-ACTING AGENTS FOR THROMBOXANE RECEPTOR ANTAGONISMAND THROMBOXANE SYNTHASE INHIBITION - 2 - DESIGN, SYNTHESIS, AND EVALUATION OF A NOVEL SERIES OF PHENYL OXAZOLE DERIVATIVES
Authors: TAKEUCHI K KOHN TJ MAIS DE TRUE TA WYSS VL JAKUBOWSKI JA
Citation: K. Takeuchi et al., DEVELOPMENT OF DUAL-ACTING AGENTS FOR THROMBOXANE RECEPTOR ANTAGONISMAND THROMBOXANE SYNTHASE INHIBITION - 2 - DESIGN, SYNTHESIS, AND EVALUATION OF A NOVEL SERIES OF PHENYL OXAZOLE DERIVATIVES, Bioorganic & medicinal chemistry letters, 8(15), 1998, pp. 1943-1948
QUANTITATIVE DETECTION OF PLATELET GPIIB-IIIA RECEPTOR ANTAGONIST ACTIVITY USING A FLOW CYTOMETRIC METHOD
Authors: GREEN LJ MARDER P UM SL JAKUBOWSKI JA LAWRENCE JB
Citation: Lj. Green et al., QUANTITATIVE DETECTION OF PLATELET GPIIB-IIIA RECEPTOR ANTAGONIST ACTIVITY USING A FLOW CYTOMETRIC METHOD, Journal of clinical laboratory analysis, 12(4), 1998, pp. 191-196
INTRAVENOUS ADMINISTRATION OF THE GLYCOPROTEIN IIB-IIIA RECEPTOR ANTAGONIST 7E3 INDUCES REPERFUSION OF AN ACUTE THROMBOTIC OCCLUSION OF THECANINE CORONARY-ARTERY
Authors: SHETLER TJ BAILEY BD JAKUBOWSKI JA JACKSON CV
Citation: Tj. Shetler et al., INTRAVENOUS ADMINISTRATION OF THE GLYCOPROTEIN IIB-IIIA RECEPTOR ANTAGONIST 7E3 INDUCES REPERFUSION OF AN ACUTE THROMBOTIC OCCLUSION OF THECANINE CORONARY-ARTERY, Thrombosis research, 90(2), 1998, pp. 95-100
DIHYDROISOQUINOLONE RGD MIMICS - EXPLORATION OF THE ASPARTATE ISOSTERE
Authors: FISHER MJ GUNN BP HARMS CS KLINE AD MULLANEY JT SCARBOROUGH RM SKELTON MA UM SL UTTERBACK BG JAKUBOWSKI JA
Citation: Mj. Fisher et al., DIHYDROISOQUINOLONE RGD MIMICS - EXPLORATION OF THE ASPARTATE ISOSTERE, Bioorganic & medicinal chemistry letters, 7(19), 1997, pp. 2537-2542
HUMAN GROUP-II 14 KDA PHOSPHOLIPASE A(2) ACTIVATES HUMAN PLATELETS
Authors: POLGAR J KRAMER RM UM SL JAKUBOWSKI JA CLEMETSON KJ
Citation: J. Polgar et al., HUMAN GROUP-II 14 KDA PHOSPHOLIPASE A(2) ACTIVATES HUMAN PLATELETS, Biochemical journal, 327, 1997, pp. 259-265
AN ACYLIMINIUM ION APPROACH TOWARDS THE SYNTHESIS OF BETA-SUBSTITUTED3,4-DIHYDROISOQUINALONE PROPIONATES
Authors: FISHER MJ GUNN BP UM S JAKUBOWSKI JA
Citation: Mj. Fisher et al., AN ACYLIMINIUM ION APPROACH TOWARDS THE SYNTHESIS OF BETA-SUBSTITUTED3,4-DIHYDROISOQUINALONE PROPIONATES, Tetrahedron letters, 38(33), 1997, pp. 5747-5750
FIBRINOGEN RECEPTOR (GPIIB-IIIA) ANTAGONISTS DERIVED FROM 5,6-BICYCLIC TEMPLATES - AMIDINOINDOLES, AMIDINOINDAZOLES, AND AMIDINOBENZOFURANSCONTAINING THE N-ALPHA-SULFONAMIDE CARBOXYLIC-ACID FUNCTION AS POTENTPLATELET-AGGREGATION INHIBITORS
Authors: SU T NAUGHTON MAH SMYTH MS ROSE JW ARFSTEN AE MCCOWAN JR JAKUBOWSKI JA WYSS VL RUTERBORIES KJ SALL DJ SCARBOROUGH RM
Citation: T. Su et al., FIBRINOGEN RECEPTOR (GPIIB-IIIA) ANTAGONISTS DERIVED FROM 5,6-BICYCLIC TEMPLATES - AMIDINOINDOLES, AMIDINOINDAZOLES, AND AMIDINOBENZOFURANSCONTAINING THE N-ALPHA-SULFONAMIDE CARBOXYLIC-ACID FUNCTION AS POTENTPLATELET-AGGREGATION INHIBITORS, Journal of medicinal chemistry, 40(26), 1997, pp. 4308-4318
USE OF CONFORMATIONALLY RESTRICTED BENZAMIDINES AS ARGININE SURROGATES IN THE DESIGN OF PLATELET GPIIB-IIIA RECEPTOR ANTAGONISTS
Authors: SALL DJ ARFSTEN AE BASTIAN JA DENNEY ML HARMS CS MCCOWAN JR MORIN JM ROSE JW SCARBOROUGH RM SMYTH MS UM SL UTTERBACK BG VASILEFF RT WIKEL JH WYSS VL JAKUBOWSKI JA
Citation: Dj. Sall et al., USE OF CONFORMATIONALLY RESTRICTED BENZAMIDINES AS ARGININE SURROGATES IN THE DESIGN OF PLATELET GPIIB-IIIA RECEPTOR ANTAGONISTS, Journal of medicinal chemistry, 40(18), 1997, pp. 2843-2857
NONPEPTIDE RGD SURROGATES WHICH MIMIC A GLY-ASP BETA-TURN - POTENT ANTAGONISTS OF PLATELET GLYCOPROTEIN IIB-IIIA
Authors: FISHER MJ GUNN B HARMS CS KLINE AD MULLANEY JT NUNES A SCARBOROUGH RM ARFSTEN AE SKELTON MA UM SL UTTERBACK BG JAKUBOWSKI JA
Citation: Mj. Fisher et al., NONPEPTIDE RGD SURROGATES WHICH MIMIC A GLY-ASP BETA-TURN - POTENT ANTAGONISTS OF PLATELET GLYCOPROTEIN IIB-IIIA, Journal of medicinal chemistry, 40(13), 1997, pp. 2085-2101
EFFECT OF CA2-IIIA INTERACTIONS WITH INTEGRILIN - ENHANCED GP IIB-IIIA BINDING AND INHIBITION OF PLATELET-AGGREGATION BY REDUCTIONS IN THE CONCENTRATION OF IONIZED CALCIUM IN PLASMA ANTICOAGULATED WITH CITRATE( ON GP IIB)
Authors: PHILLIPS DR TENG W ARFSTEN A NANNIZZIALAIMO L WHITE MM LONGHURST C SHATTIL SJ RANDOLPH A JAKUBOWSKI JA JENNINGS LK SCARBOROUGH RM
Citation: Dr. Phillips et al., EFFECT OF CA2-IIIA INTERACTIONS WITH INTEGRILIN - ENHANCED GP IIB-IIIA BINDING AND INHIBITION OF PLATELET-AGGREGATION BY REDUCTIONS IN THE CONCENTRATION OF IONIZED CALCIUM IN PLASMA ANTICOAGULATED WITH CITRATE( ON GP IIB), Circulation, 96(5), 1997, pp. 1488-1494
ANALYSIS OF FIBRINOGEN BINDING TO PLATELETS AND QUANTITATIVE DETECTION OF PLATELET IIB IIIA RECEPTOR ANTAGONIST ACTIVITY USING FLOW CYTOMETRIC METHODS/
Authors: MARDER P GREEN LJ UM SL JAKUBOWSKI JA LAWRENCE JB
Citation: P. Marder et al., ANALYSIS OF FIBRINOGEN BINDING TO PLATELETS AND QUANTITATIVE DETECTION OF PLATELET IIB IIIA RECEPTOR ANTAGONIST ACTIVITY USING FLOW CYTOMETRIC METHODS/, Molecular biology of the cell, 7, 1996, pp. 1437-1437
PLATELET GLYCOPROTEIN IIB-IIIA RECEPTOR (GPIIB-IIIA) ANTAGONISTS DERIVED FROM AMIDINOINDOLES
Authors: SALL DJ ARFSTEN AE BERRY DR DENNEY ML HARMS CS MCCOWAN JR RAY JK SCARBOROUGH RM UM SL UTTERBACK BG JAKUBOWSKI JA
Citation: Dj. Sall et al., PLATELET GLYCOPROTEIN IIB-IIIA RECEPTOR (GPIIB-IIIA) ANTAGONISTS DERIVED FROM AMIDINOINDOLES, Bioorganic & medicinal chemistry letters, 6(1), 1996, pp. 81-86
ACTIVATION OF P38 MAP KINASE AND CA2-SENSITIVE CYTOSOLIC PHOSPHOLIPASE A(2) IN HUMAN PLATELETS()
Authors: KRAMER RM ROBERTS EF UM SL FISHER MJ JAKUBOWSKI JA
Citation: Rm. Kramer et al., ACTIVATION OF P38 MAP KINASE AND CA2-SENSITIVE CYTOSOLIC PHOSPHOLIPASE A(2) IN HUMAN PLATELETS(), The FASEB journal, 10(6), 1996, pp. 18-18
ACTIVATION OF P38 MAP KINASE AND CA2-SENSITIVE CYTOSOLIC PHOSPHOLIPASE A(2) IN HUMAN PLATELETS()
Authors: KRAMER RM ROBERTS EF UM SL FISHER MJ JAKUBOWSKI JA
Citation: Rm. Kramer et al., ACTIVATION OF P38 MAP KINASE AND CA2-SENSITIVE CYTOSOLIC PHOSPHOLIPASE A(2) IN HUMAN PLATELETS(), The FASEB journal, 10(6), 1996, pp. 1470-1470
P38 MITOGEN-ACTIVATED PROTEIN-KINASE PHOSPHORYLATES CYTOSOLIC PHOSPHOLIPASE A(2) (CPLA(2)) IN THROMBIN-STIMULATED PLATELETS - EVIDENCE THATPROLINE-DIRECTED PHOSPHORYLATION IS NOT REQUIRED FOR MOBILIZATION OF ARACHIDONIC-ACID BY CPLA(2)
Authors: KRAMER RM ROBERTS EF UM SL BORSCHHAUBOLD AG WATSON SP FISHER MJ JAKUBOWSKI JA
Citation: Rm. Kramer et al., P38 MITOGEN-ACTIVATED PROTEIN-KINASE PHOSPHORYLATES CYTOSOLIC PHOSPHOLIPASE A(2) (CPLA(2)) IN THROMBIN-STIMULATED PLATELETS - EVIDENCE THATPROLINE-DIRECTED PHOSPHORYLATION IS NOT REQUIRED FOR MOBILIZATION OF ARACHIDONIC-ACID BY CPLA(2), The Journal of biological chemistry, 271(44), 1996, pp. 27723-27729
IN-VIVO EFFECTS OF A NOVEL THROMBOXANE A(2) PROSTAGLANDIN H-2 (TXA(2)PGH(2)) PARTIAL AGONIST, LFONYLAMINO[2.2.1]-BICYCLOHEPT-2-EXO-YL]-HEPTENOIC ACID [(+)-S-145], ON VASCULAR, PLATELET AND CARDIAC-FUNCTION()5(Z))
Authors: DUBE GP JAKUBOWSKI JA BRUNE KA BEMIS KG KURTZ WL
Citation: Gp. Dube et al., IN-VIVO EFFECTS OF A NOVEL THROMBOXANE A(2) PROSTAGLANDIN H-2 (TXA(2)PGH(2)) PARTIAL AGONIST, LFONYLAMINO[2.2.1]-BICYCLOHEPT-2-EXO-YL]-HEPTENOIC ACID [(+)-S-145], ON VASCULAR, PLATELET AND CARDIAC-FUNCTION()5(Z)), The Journal of pharmacology and experimental therapeutics, 272(2), 1995, pp. 799-807
DIFFERENTIAL ACTIVATION OF CYTOSOLIC PHOSPHOLIPASE A(2) (CPLA(2)) BY THROMBIN AND THROMBIN RECEPTOR AGONIST PEPTIDE IN HUMAN PLATELETS - EVIDENCE FOR ACTIVATION OF CPLA(2) INDEPENDENT OF THE MITOGEN-ACTIVATED PROTEIN-KINASES ERK1 2/
Authors: KRAMER RM ROBERTS EF HYSLOP PA UTTERBACK BG HUI KY JAKUBOWSKI JA
Citation: Rm. Kramer et al., DIFFERENTIAL ACTIVATION OF CYTOSOLIC PHOSPHOLIPASE A(2) (CPLA(2)) BY THROMBIN AND THROMBIN RECEPTOR AGONIST PEPTIDE IN HUMAN PLATELETS - EVIDENCE FOR ACTIVATION OF CPLA(2) INDEPENDENT OF THE MITOGEN-ACTIVATED PROTEIN-KINASES ERK1 2/, The Journal of biological chemistry, 270(24), 1995, pp. 14816-14823
THROMBIN INHIBITION BY NOVEL ARGINAL TRIPEPTIDE LY296516 FAILS TO INHIBIT INTIMAL THICKENING IN A RABBIT MODEL OF ARTERIAL INJURY
Authors: DUBE GP KURTZ WL BRUNE KA SHUMAN RT JAKUBOWSKI JA CRAFT TJ COFFMAN WJ SMITH GF
Citation: Gp. Dube et al., THROMBIN INHIBITION BY NOVEL ARGINAL TRIPEPTIDE LY296516 FAILS TO INHIBIT INTIMAL THICKENING IN A RABBIT MODEL OF ARTERIAL INJURY, Circulation, 92(8), 1995, pp. 162-162
ACTIVATION OF CA2-SENSITIVE PHOSPHOLIPASE-A(2) (CPLA2) BY THROMBIN INHUMAN PLATELETS()
Authors: KRAMER RM ROBERTS EF MANETTA JV JAKUBOWSKI JA
Citation: Rm. Kramer et al., ACTIVATION OF CA2-SENSITIVE PHOSPHOLIPASE-A(2) (CPLA2) BY THROMBIN INHUMAN PLATELETS(), Journal of cellular biochemistry, 1994, pp. 22-22
ACTIVATION OF CA2-SENSITIVE PHOSPHOLIPASE-A(2) (CPLA2) BY THROMBIN INHUMAN PLATELETS()
Authors: KRAMER RM ROBERTS E MANETTA JV JAKUBOWSKI JA
Citation: Rm. Kramer et al., ACTIVATION OF CA2-SENSITIVE PHOSPHOLIPASE-A(2) (CPLA2) BY THROMBIN INHUMAN PLATELETS(), Journal of cellular biochemistry, 1994, pp. 69-69
BIOCHEMICAL AND PHARMACOLOGICAL ACTIVITY OF ARENE-FUSED PROSTACYCLIN ANALOGS ON HUMAN PLATELETS
Authors: JAKUBOWSKI JA UTTERBACK BG MAIS DE HARDINGER SA BRAISH TF NEVILL CR FUCHS PL
Citation: Ja. Jakubowski et al., BIOCHEMICAL AND PHARMACOLOGICAL ACTIVITY OF ARENE-FUSED PROSTACYCLIN ANALOGS ON HUMAN PLATELETS, Prostaglandins, 47(3), 1994, pp. 189-201
CORRELATION OF MOLECULAR SHAPE WITH GPIIB-IIIA RECEPTOR ANTAGONIST ACTIVITY IN RGD PEPTIDES
Authors: TUNG JS JAKUBOWSKI JA HEATH WF UTTERBACK BG HERRON DK
Citation: Js. Tung et al., CORRELATION OF MOLECULAR SHAPE WITH GPIIB-IIIA RECEPTOR ANTAGONIST ACTIVITY IN RGD PEPTIDES, Receptor, 3(4), 1993, pp. 343-356
CA2-SENSITIVE CYTOSOLIC PHOSPHOLIPASE-A(2) (CPLA(2)) IN HUMAN PLATELETS()
Authors: KRAMER RM ROBERTS EF MANETTA JV SPORTSMAN JR JAKUBOWSKI JA
Citation: Rm. Kramer et al., CA2-SENSITIVE CYTOSOLIC PHOSPHOLIPASE-A(2) (CPLA(2)) IN HUMAN PLATELETS(), Journal of lipid mediators, 6(1-3), 1993, pp. 209-216
THROMBIN-INDUCED PHOSPHORYLATION AND ACTIVATION OF CA2-SENSITIVE CYTOSOLIC PHOSPHOLIPASE-A(2) IN HUMAN PLATELETS()
Authors: KRAMER RM ROBERTS EF MANETTA JV HYSLOP PA JAKUBOWSKI JA
Citation: Rm. Kramer et al., THROMBIN-INDUCED PHOSPHORYLATION AND ACTIVATION OF CA2-SENSITIVE CYTOSOLIC PHOSPHOLIPASE-A(2) IN HUMAN PLATELETS(), The Journal of biological chemistry, 268(35), 1993, pp. 26796-26804
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