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Results: 1-25 | 26-26
Results: 1-25/26
STRUCTURE AND MECHANISM OF ACTION OF NONNUCLEOSIDE INHIBITORS OF HIV-1 REVERSE-TRANSCRIPTASE - STRATEGIES TO COMBAT DRUG-RESISTANCE
Authors: SMITH RH MICHEJDA CJ HUGHES SH ARNOLD E JANSSEN PAJ SMITH MBK
Citation: Rh. Smith et al., STRUCTURE AND MECHANISM OF ACTION OF NONNUCLEOSIDE INHIBITORS OF HIV-1 REVERSE-TRANSCRIPTASE - STRATEGIES TO COMBAT DRUG-RESISTANCE, Journal of molecular structure. Theochem, 423(1-2), 1998, pp. 67-77
NIEMEGEERS,CARLOS,J.E. (1927-1997)
Authors: JANSSEN PAJ AWOUTERS FHL LEYSEN JE MEGENS AAHP
Citation: Paj. Janssen et al., NIEMEGEERS,CARLOS,J.E. (1927-1997), Psychopharmacology, 134(3), 1997, pp. 318-318
THE ALPHA AND OMEGA OF G-PROTEIN COUPLED RECEPTORS - A NOVEL METHOD FOR CLASSIFICATION PART-2 BIN CLASSIFICATION
Authors: MOEREELS H LEWI PJ DAEYAERT F SCHENCK E JANSSEN PAJ
Citation: H. Moereels et al., THE ALPHA AND OMEGA OF G-PROTEIN COUPLED RECEPTORS - A NOVEL METHOD FOR CLASSIFICATION PART-2 BIN CLASSIFICATION, Receptors & channels, 5(3-4), 1997, pp. 139-148
MOLECULAR MODELING OF HIV-1 REVERSE-TRANSCRIPTASE DRUG-RESISTANT MUTANT STRAINS - IMPLICATIONS FOR THE MECHANISM OF POLYMERASE ACTION
Authors: SMITH MBK MICHEJDA CJ HUGHES SH BOYER PL JANSSEN PAJ ANDRIES K BUCKHEIT RW SMITH RH
Citation: Mbk. Smith et al., MOLECULAR MODELING OF HIV-1 REVERSE-TRANSCRIPTASE DRUG-RESISTANT MUTANT STRAINS - IMPLICATIONS FOR THE MECHANISM OF POLYMERASE ACTION, Protein engineering, 10(12), 1997, pp. 1379-1383
THE ALPHA AND OMEGA OF G-PROTEIN COUPLED RECEPTORS - A NOVEL METHOD FOR CLASSIFICATION .1.
Authors: MOEREELS H LEWI PJ KOYMANS LMH JANSSEN PAJ
Citation: H. Moereels et al., THE ALPHA AND OMEGA OF G-PROTEIN COUPLED RECEPTORS - A NOVEL METHOD FOR CLASSIFICATION .1., Receptors & channels, 4(1), 1996, pp. 19-30
CRYSTAL-STRUCTURES OF 8-CL AND 9-CL TIBO COMPLEXED WITH WILD-TYPE HIV-1 RT AND 8-CL TIBO COMPLEXED WITH THE TYR181CYS HIV-1 RT DRUG-RESISTANT MUTANT
Authors: DAS K DING JP HSIOU Y CLARK AD MOEREELS H KOYMANS L ANDRIES K PAUWELS R JANSSEN PAJ BOYER PL CLARK P SMITH RH SMITH MBK MICHEJDA CJ HUGHES SH ARNOLD E
Citation: K. Das et al., CRYSTAL-STRUCTURES OF 8-CL AND 9-CL TIBO COMPLEXED WITH WILD-TYPE HIV-1 RT AND 8-CL TIBO COMPLEXED WITH THE TYR181CYS HIV-1 RT DRUG-RESISTANT MUTANT, Journal of Molecular Biology, 264(5), 1996, pp. 1085-1100
THE ROLE OF NUCLEIC-ACID IN THE RESISTANCE OF HIV-1 REVERSE-TRANSCRIPTASE TO NUCLEOSIDE AND NONNUCLEOSIDE INHIBITORS
Authors: ARNOLD E DAS K DING JP HSIOU Y TANTILLO C ROY BM YADAV P ZHANG WY LENTZ K CLARK AD BOYER PL HUGHES SH MITSUYA H MELLORS J KLEIM JP ROSNER M MOEREELS HR KOYMANS L ANDRIES K PAUWELS R JANSSEN PAJ
Citation: E. Arnold et al., THE ROLE OF NUCLEIC-ACID IN THE RESISTANCE OF HIV-1 REVERSE-TRANSCRIPTASE TO NUCLEOSIDE AND NONNUCLEOSIDE INHIBITORS, Journal of acquired immune deficiency syndromes and human retrovirology, 10, 1995, pp. 7-7
8-CHLORO-TIBO (R091767) AND AZT IN COMBINATION CAN PREVENT THE APPEARANCE OF RESISTANT HIV IN-VITRO
Authors: DEBETHUNE MP AZIJN H HERTOGS K ANDRIES K JANSSEN PAJ PAUWELS R
Citation: Mp. Debethune et al., 8-CHLORO-TIBO (R091767) AND AZT IN COMBINATION CAN PREVENT THE APPEARANCE OF RESISTANT HIV IN-VITRO, Journal of acquired immune deficiency syndromes and human retrovirology, 10, 1995, pp. 15-15
DESIGN OF AN EXPERIMENTAL ASSAY THAT MIGHT BE OF PROGNOSTIC VALUE FORANTI-HIV COMBINATION THERAPY
Authors: AZIJN H DEBETHUNE MP HERTOGS K ANDRIES K JANSSEN PAJ PAUWELS R
Citation: H. Azijn et al., DESIGN OF AN EXPERIMENTAL ASSAY THAT MIGHT BE OF PROGNOSTIC VALUE FORANTI-HIV COMBINATION THERAPY, Journal of acquired immune deficiency syndromes and human retrovirology, 10, 1995, pp. 86-86
STRUCTURE OF HIV-1 RT TIBO R-86183 COMPLEX REVEALS SIMILARITY IN THE BINDING OF DIVERSE NONNUCLEOSIDE INHIBITORS/
Authors: DING JP DAS K MOEREELS H KOYMANS L ANDRIES K JANSSEN PAJ HUGHES SH ARNOLD E
Citation: Jp. Ding et al., STRUCTURE OF HIV-1 RT TIBO R-86183 COMPLEX REVEALS SIMILARITY IN THE BINDING OF DIVERSE NONNUCLEOSIDE INHIBITORS/, Nature structural biology, 2(5), 1995, pp. 407-415
STRUCTURE OF HIV-1 REVERSE-TRANSCRIPTASE IN A COMPLEX WITH THE NONNUCLEOSIDE INHIBITOR ALPHA-APA-R-95845 AT 2.8-ANGSTROM RESOLUTION
Authors: DING J DAS K TANTILLO C ZHANG W CLARK AD JESSEN S LU X HSIOU Y JACOBOMOLINA A ANDRIES K PAUWELS R MOEREELS H KOYMANS L JANSSEN PAJ SMITH RH KOEPKE MK MICHEJDA CJ HUGHES SH ARNOLD E
Citation: J. Ding et al., STRUCTURE OF HIV-1 REVERSE-TRANSCRIPTASE IN A COMPLEX WITH THE NONNUCLEOSIDE INHIBITOR ALPHA-APA-R-95845 AT 2.8-ANGSTROM RESOLUTION, Structure, 3(4), 1995, pp. 365-379
MOLECULAR MODELING STUDIES OF HIV-1 REVERSE-TRANSCRIPTASE NONNUCLEOSIDE INHIBITORS - TOTAL-ENERGY OF COMPLEXATION AS A PREDICTOR OF DRUG PLACEMENT AND ACTIVITY
Authors: SMITH MBK ROUZER CA TANEYHILL LA SMITH NA HUGHES SH BOYER PL JANSSEN PAJ MOEREELS H KOYMANS L ARNOLD E DING JP DAS K ZHANG WY MICHEJDA CJ SMITH RH
Citation: Mbk. Smith et al., MOLECULAR MODELING STUDIES OF HIV-1 REVERSE-TRANSCRIPTASE NONNUCLEOSIDE INHIBITORS - TOTAL-ENERGY OF COMPLEXATION AS A PREDICTOR OF DRUG PLACEMENT AND ACTIVITY, Protein science, 4(10), 1995, pp. 2203-2222
IMMUNOLOGICAL ALTERATIONS INDUCED BY ADJUVANT TREATMENT OF POSTOPERATIVE COLON-CARCINOMA DUKES-B OR DUKES-C WITH LEVAMISOLE IN COMBINATION WITH 5-FU
Authors: DEBRABANDER M VANDEBROEK J WASSENAAR H DECREE J BAISIER A DEMOEN B DERIDDER R JAGERS E ROELS V VOGELS O VERHAEGEN H JANSSEN PAJ
Citation: M. Debrabander et al., IMMUNOLOGICAL ALTERATIONS INDUCED BY ADJUVANT TREATMENT OF POSTOPERATIVE COLON-CARCINOMA DUKES-B OR DUKES-C WITH LEVAMISOLE IN COMBINATION WITH 5-FU, Anticancer research, 15(5), 1995, pp. 2271-2277
INTRANASAL PIRODAVIR (R77,975) TREATMENT OF RHINOVIRUS COLDS
Authors: HAYDEN FG HIPSKIND GJ WOERNER DH EISEN GF JANSSENS M JANSSEN PAJ ANDRIES K
Citation: Fg. Hayden et al., INTRANASAL PIRODAVIR (R77,975) TREATMENT OF RHINOVIRUS COLDS, Antimicrobial agents and chemotherapy, 39(2), 1995, pp. 290-294
SYNTHESIS AND ANTI-HIV-1 ACTIVITY OF ETHYLIMIDAZO[4,5,1-JK][1,4]BENZODIAZEPIN-2(1H)-ONE (TIBO) DERIVATIVES .3.
Authors: BRESLIN HJ KUKLA MJ LUDOVICI DW MOHRBACHER R HO W MIRANDA M RODGERS JD HITCHENS TK LEO G GAUTHIER DA HO CY SCOTT MK DECLERCQ E PAUWELS R ANDRIES K JANSSEN MAC JANSSEN PAJ
Citation: Hj. Breslin et al., SYNTHESIS AND ANTI-HIV-1 ACTIVITY OF ETHYLIMIDAZO[4,5,1-JK][1,4]BENZODIAZEPIN-2(1H)-ONE (TIBO) DERIVATIVES .3., Journal of medicinal chemistry, 38(5), 1995, pp. 771-793
SYNTHESIS AND ANTI-HIV-1 ACTIVITY OF ETHYLIMIDAZO[4,5,1-JK][1,4]BENZODIAZEPIN-2(1H)-ONE (TIBO) DERIVATIVES .4.
Authors: HO W KUKLA MJ BRESLIN HJ LUDOVICI DW GROUS PP DIAMOND CJ MIRANDA M RODGERS JD HO CY DECLERCQ E PAUWELS R ANDRIES K JANSSEN MAC JANSSEN PAJ
Citation: W. Ho et al., SYNTHESIS AND ANTI-HIV-1 ACTIVITY OF ETHYLIMIDAZO[4,5,1-JK][1,4]BENZODIAZEPIN-2(1H)-ONE (TIBO) DERIVATIVES .4., Journal of medicinal chemistry, 38(5), 1995, pp. 794-802
CELL-BASED AND BIOCHEMICAL-ANALYSIS OF THE ANTI-HIV ACTIVITY OF COMBINATIONS OF 3'-AZIDO-3'-DEOXYTHYMIDINE AND ANALOGS OF TIBO
Authors: BUCKHEIT RW WHITE EL GERMANYDECKER J ALLEN LB ROSS LJ SHANNON WM JANSSEN PAJ CHIRIGOS MA
Citation: Rw. Buckheit et al., CELL-BASED AND BIOCHEMICAL-ANALYSIS OF THE ANTI-HIV ACTIVITY OF COMBINATIONS OF 3'-AZIDO-3'-DEOXYTHYMIDINE AND ANALOGS OF TIBO, Antiviral chemistry & chemotherapy, 5(1), 1994, pp. 35-42
CHARACTERIZATION OF HIV-1 STRAINS ISOLATED FROM PATIENTS TREATED WITHTIBO R82913
Authors: VANDAMME AM DEBYSER Z PAUWELS R DEVREESE K GOUBAU P YOULE M GAZZARD B STOFFELS PA CAUWENBERGH GF ANNE J ANDRIES K JANSSEN PAJ DESMYTER J DECLERCQ E
Citation: Am. Vandamme et al., CHARACTERIZATION OF HIV-1 STRAINS ISOLATED FROM PATIENTS TREATED WITHTIBO R82913, AIDS research and human retroviruses, 10(1), 1994, pp. 39-46
NEW YDROIMIDAZO[4,5,1-JK][1,4]-BENZODIAZEPIN-2(1H)-ONE AND OIMIDAZO[4,5,1-JK][1,4]-BENZODIAZEPIN-2(1H)-THIONE DERIVATIVES ARE POTENT INHIBITORS OF HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 REPLICATION AND ARE SYNERGISTIC WITH 2',3'-DIDEOXYNUCLEOSIDE ANALOGS
Authors: PAUWELS R ANDRIES K DEBYSER Z KUKLA MJ SCHOLS D BRESLIN HJ WOESTENBORGHS R DESMYTER J JANSSEN MAC DECLERCQ E JANSSEN PAJ
Citation: R. Pauwels et al., NEW YDROIMIDAZO[4,5,1-JK][1,4]-BENZODIAZEPIN-2(1H)-ONE AND OIMIDAZO[4,5,1-JK][1,4]-BENZODIAZEPIN-2(1H)-THIONE DERIVATIVES ARE POTENT INHIBITORS OF HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 REPLICATION AND ARE SYNERGISTIC WITH 2',3'-DIDEOXYNUCLEOSIDE ANALOGS, Antimicrobial agents and chemotherapy, 38(12), 1994, pp. 2863-2870
INHIBITION OF 5-HYDROXYTRYPTAMINE-INDUCED AND 5-HYDROXYTRYPTAMINE-AMPLIFIED HUMAN PLATELET-AGGREGATION BY KETANSERIN (R-41-468), A SELECTIVE 5-HT(2)-RECEPTOR ANTAGONIST
Authors: DECLERCK F DAVID JL JANSSEN PAJ
Citation: F. Declerck et al., INHIBITION OF 5-HYDROXYTRYPTAMINE-INDUCED AND 5-HYDROXYTRYPTAMINE-AMPLIFIED HUMAN PLATELET-AGGREGATION BY KETANSERIN (R-41-468), A SELECTIVE 5-HT(2)-RECEPTOR ANTAGONIST, Agents and actions, 43(3-4), 1994, pp. 225-234
LOCATIONS OF ANTI-AIDS DRUG-BINDING SITES AND RESISTANCE MUTATIONS INTHE 3-DIMENSIONAL STRUCTURE OF HIV-1 REVERSE-TRANSCRIPTASE - IMPLICATIONS FOR MECHANISMS OF DRUG-INHIBITION AND RESISTANCE
Authors: TANTILLO C DING JP JACOBOMOLINA A NANNI RG BOYER PL HUGHES SH PAUWELS R ANDRIES K JANSSEN PAJ ARNOLD E
Citation: C. Tantillo et al., LOCATIONS OF ANTI-AIDS DRUG-BINDING SITES AND RESISTANCE MUTATIONS INTHE 3-DIMENSIONAL STRUCTURE OF HIV-1 REVERSE-TRANSCRIPTASE - IMPLICATIONS FOR MECHANISMS OF DRUG-INHIBITION AND RESISTANCE, Journal of Molecular Biology, 243(3), 1994, pp. 369-387
IS IT POSSIBLE TO PREDICT THE CLINICAL EFFECTS OF NEUROLEPTICS FROM ANIMAL DATA .5. FROM HALOPERIDOL AND PIPAMPERONE TO RISPERIDONE
Authors: JANSSEN PAJ AWOUTERS FHL
Citation: Paj. Janssen et Fhl. Awouters, IS IT POSSIBLE TO PREDICT THE CLINICAL EFFECTS OF NEUROLEPTICS FROM ANIMAL DATA .5. FROM HALOPERIDOL AND PIPAMPERONE TO RISPERIDONE, Arzneimittel-Forschung, 44-1(3), 1994, pp. 269-277
DIFFERENTIAL ANTIVIRAL ACTIVITY OF 2 TIBO DERIVATIVES AGAINST THE HUMAN IMMUNODEFICIENCY AND MURINE LEUKEMIA VIRUSES ALONE AND IN COMBINATION WITH OTHER ANTI-HIV AGENTS
Authors: BUCKHEIT RW GERMANYDECKER J HOLLINGSHEAD MG ALLEN LB SHANNON WM JANSSEN PAJ CHIRIGOS MA
Citation: Rw. Buckheit et al., DIFFERENTIAL ANTIVIRAL ACTIVITY OF 2 TIBO DERIVATIVES AGAINST THE HUMAN IMMUNODEFICIENCY AND MURINE LEUKEMIA VIRUSES ALONE AND IN COMBINATION WITH OTHER ANTI-HIV AGENTS, AIDS research and human retroviruses, 9(11), 1993, pp. 1097-1106
LOPERAMIDE - SURVEY OF STUDIES ON MECHANISM OF ITS ANTIDIARRHEAL ACTIVITY
Authors: AWOUTERS F MEGENS A VERLINDEN M SCHUURKES J NIEMEGEERS C JANSSEN PAJ
Citation: F. Awouters et al., LOPERAMIDE - SURVEY OF STUDIES ON MECHANISM OF ITS ANTIDIARRHEAL ACTIVITY, Digestive diseases and sciences, 38(6), 1993, pp. 977-995
INVITRO AND INVIVO RECEPTOR-BINDING AND EFFECTS ON MONOAMINE TURNOVERIN RAT-BRAIN REGIONS OF THE NOVEL ANTIPSYCHOTICS RISPERIDONE AND OCAPERIDONE
Authors: LEYSEN JE JANSSEN PMF GOMMEREN W WYNANTS J PAUWELS PJ JANSSEN PAJ
Citation: Je. Leysen et al., INVITRO AND INVIVO RECEPTOR-BINDING AND EFFECTS ON MONOAMINE TURNOVERIN RAT-BRAIN REGIONS OF THE NOVEL ANTIPSYCHOTICS RISPERIDONE AND OCAPERIDONE, Molecular pharmacology, 41(3), 1992, pp. 494-508
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