AAAAAA

   
Results: 1-16 |
Results: 16
Biosynthesis and processing of cathepsin K in cultured human osteoclasts
Authors: Rieman, DJ McClung, HA Dodds, RA Hwang, SM Lark, MW Holmes, S James, IE Drake, FH Gowen, M
Citation: Dj. Rieman et al., Biosynthesis and processing of cathepsin K in cultured human osteoclasts, BONE, 28(3), 2001, pp. 282-289
Human osteoclast cathepsin K is processed intracellularly prior to attachment and bone resorption
Authors: Dodds, RA James, IE Rieman, D Ahern, R Hwang, SM Connor, JR Thompson, SD Veber, DF Drake, FH Holmes, S Lark, MW Gowen, M
Citation: Ra. Dodds et al., Human osteoclast cathepsin K is processed intracellularly prior to attachment and bone resorption, J BONE MIN, 16(3), 2001, pp. 478-486
Antagonism of the osteoclast vitronectin receptor with an orally active nonpeptide inhibitor prevents cancellous bone loss in the ovariectomized rat
Authors: Lark, MW Stroup, GB Dodds, RA Kapadia, R Hoffman, SJ Hwang, SM James, IE Lechowska, B Liang, XG Rieman, DJ Salyers, KL Ward, K Smith, BR Miller, WH Huffman, WF Gowen, M
Citation: Mw. Lark et al., Antagonism of the osteoclast vitronectin receptor with an orally active nonpeptide inhibitor prevents cancellous bone loss in the ovariectomized rat, J BONE MIN, 16(2), 2001, pp. 319-327
Potent and selective inhibition of human cathepsin K leads to inhibition of bone resorption in vivo in a nonhuman primate
Authors: Stroup, GB Lark, MW Veber, DF Bhattacharyya, A Blake, S Dare, LC Erhard, KF Hoffman, SJ James, IE Marquis, RW Ru, Y Vasko-Moser, JA Smith, BR Tomaszek, T Gowen, M
Citation: Gb. Stroup et al., Potent and selective inhibition of human cathepsin K leads to inhibition of bone resorption in vivo in a nonhuman primate, J BONE MIN, 16(10), 2001, pp. 1739-1746
Azepanone-based inhibitors of human and rat cathepsin K
Authors: Marquis, RW Ru, Y LoCastro, SM Zeng, J Yamashita, DS Oh, HJ Erhard, KF Davis, LD Tomaszek, TA Tew, D Salyers, K Proksch, J Ward, K Smith, B Levy, M Cummings, MD Haltiwanger, RC Trescher, G Wang, B Hemling, ME Quinn, CJ Cheng, HY Lin, F Smith, WW Janson, CA Zhao, BG McQueney, MS D'Alessio, K Lee, CP Marzulli, A Dodds, RA Blake, S Hwang, SM James, IE Gress, CJ Bradley, BR Lark, MW Gowen, M Veber, DF
Citation: Rw. Marquis et al., Azepanone-based inhibitors of human and rat cathepsin K, J MED CHEM, 44(9), 2001, pp. 1380-1395
Potent and selective cathepsin L inhibitors do not inhibit human osteoclast resorption in vitro
Authors: James, IE Marquis, RW Blake, SM Hwang, SM Gress, CJ Ru, Y Zembryki, D Yamashita, DS McQueney, MS Tomaszek, TA Oh, HJ Gowen, M Veber, DF Lark, MW
Citation: Ie. James et al., Potent and selective cathepsin L inhibitors do not inhibit human osteoclast resorption in vitro, J BIOL CHEM, 276(15), 2001, pp. 11507-11511
FrzB-2: a human secreted frizzled-related protein with a potential role inchondrocyte apoptosis
Authors: James, IE Kumar, S Barnes, MR Gress, CJ Hand, AT Dodds, RA Connor, JR Bradley, BR Campbell, DA Grabill, SE Williams, K Blake, SM Gowen, M Lark, MW
Citation: Ie. James et al., FrzB-2: a human secreted frizzled-related protein with a potential role inchondrocyte apoptosis, OSTEO CART, 8(6), 2000, pp. 452-463
Differential expression of Egr-1 in osteoarthritic compared to normal adult human articular cartilage
Authors: Wang, FL Connor, JR Dodds, RA James, IE Kumar, S Zou, C Lark, MW Gowen, M Nuttall, ME
Citation: Fl. Wang et al., Differential expression of Egr-1 in osteoarthritic compared to normal adult human articular cartilage, OSTEO CART, 8(3), 2000, pp. 161-169
Discovery of orally active nonpeptide vitronectin receptor antagonists based on a 2-benzazepine Gly-Asp mimetic
Authors: Miller, WH Alberts, DP Bhatnagar, PK Bondinell, WE Callahan, JF Calvo, RR Cousins, RD Erhard, KF Heerding, DA Keenan, RM Kwon, C Manley, PJ Newlander, KA Ross, ST Samanen, JM Uzinskas, IN Venslavsky, JW Yuan, CCK Haltiwanger, RC Gowen, M Hwang, SM James, IE Lark, MW Rieman, DJ Stroup, GB Azzarano, LM Salyers, KL Smith, BR Ward, KW Johanson, KO Huffman, WF
Citation: Wh. Miller et al., Discovery of orally active nonpeptide vitronectin receptor antagonists based on a 2-benzazepine Gly-Asp mimetic, J MED CHEM, 43(1), 2000, pp. 22-26
Antagonizing the parathyroid calcium receptor stimulates parathyroid hormone secretion and bone formation in osteopenic rats
Authors: Gowen, M Stroup, GB Dodds, RA James, IE Votta, BJ Smith, BR Bhatnagar, PK Lago, AM Callahan, JF DelMar, EG Miller, MA Nemeth, EF Fox, J
Citation: M. Gowen et al., Antagonizing the parathyroid calcium receptor stimulates parathyroid hormone secretion and bone formation in osteopenic rats, J CLIN INV, 105(11), 2000, pp. 1595-1604
CK beta-8 [CCL23], a novel CC chemokine, is chemotactic for human osteoclast precursors and is expressed in bone tissues
Authors: Votta, BJ White, JR Dodds, RA James, IE Connor, JR Lee-Rykaczewski, E Eichman, CF Kumar, S Lark, MW Gowen, M
Citation: Bj. Votta et al., CK beta-8 [CCL23], a novel CC chemokine, is chemotactic for human osteoclast precursors and is expressed in bone tissues, J CELL PHYS, 183(2), 2000, pp. 196-207
Injurious mechanical compression of bovine articular cartilage induces chondrocyte apoptosis
Authors: Loening, AM James, IE Levenston, ME Badger, AM Frank, EH Kurz, B Nuttall, ME Hung, HH Blake, SM Grodzinsky, AJ Lark, MW
Citation: Am. Loening et al., Injurious mechanical compression of bovine articular cartilage induces chondrocyte apoptosis, ARCH BIOCH, 381(2), 2000, pp. 205-212
Orally bioavailable nonpeptide vitronectin receptor antagonists with efficacy in an osteoporosis model
Authors: Miller, WH Bondinell, WE Cousins, RD Erhard, KF Jakas, DR Keenan, RM Ku, TW Newlander, KA Ross, ST Haltiwanger, RC Bradbeer, J Drake, FH Gowen, M Hoffman, SJ Hwang, SM James, IE Lark, MW Lechowska, B Rieman, DJ Stroup, GB Vasko-Moser, JA Zembryki, DL Azzarano, LM Adams, PC Salyers, KL Smith, BR Ward, KW Johanson, KO Huffman, WF
Citation: Wh. Miller et al., Orally bioavailable nonpeptide vitronectin receptor antagonists with efficacy in an osteoporosis model, BIOORG MED, 9(13), 1999, pp. 1807-1812
Development and characterization of a human in vitro resorption assay: Demonstration of utility using novel antiresorptive agents
Authors: James, IE Lark, MW Zembryki, D Lee-Rykaczewski, EV Hwang, SM Tomaszek, TA Belfiore, P Gowen, M
Citation: Ie. James et al., Development and characterization of a human in vitro resorption assay: Demonstration of utility using novel antiresorptive agents, J BONE MIN, 14(9), 1999, pp. 1562-1569
Design and characterization of orally active Arg-Gly-Asp peptidomimetic vitronectin receptor antagonist SB 265123 for prevention of bone loss in osteoporosis
Authors: Lark, MW Stroup, GB Hwang, SM James, IE Rieman, DJ Drake, FH Bradbeer, JN Mathur, A Erhard, KF Newlander, KA Ross, ST Salyers, KL Smith, BR Miller, WH Huffman, WF Gowen, M
Citation: Mw. Lark et al., Design and characterization of orally active Arg-Gly-Asp peptidomimetic vitronectin receptor antagonist SB 265123 for prevention of bone loss in osteoporosis, J PHARM EXP, 291(2), 1999, pp. 612-617
Identification and cloning of a connective tissue growth factor-like cDNA from human osteoblasts encoding a novel regulator of osteoblast functions
Authors: Kumar, S Hand, AT Connor, JR Dodds, RA Ryan, PJ Trill, JJ Fisher, SM Nuttall, ME Lipshutz, DB Zou, C Hwang, SM Votta, BJ James, IE Rieman, DJ Gowen, M Lee, JC
Citation: S. Kumar et al., Identification and cloning of a connective tissue growth factor-like cDNA from human osteoblasts encoding a novel regulator of osteoblast functions, J BIOL CHEM, 274(24), 1999, pp. 17123-17131
Risultati: 1-16 |