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Results: 1-23 |
Results: 23
Constitutive activation of Stat3 by the Src and JAK tyrosine kinases participates in growth regulation of human breast carcinoma cells
Authors: Garcia, R Bowman, TL Niu, GL Yu, H Minton, S Muro-Cacho, CA Cox, CE Falcone, R Fairclough, R Parsons, S Laudano, A Gazit, A Levitzki, A Kraker, A Jove, R
Citation: R. Garcia et al., Constitutive activation of Stat3 by the Src and JAK tyrosine kinases participates in growth regulation of human breast carcinoma cells, ONCOGENE, 20(20), 2001, pp. 2499-2513
Role of the cytoplasmic tyrosines of beta 1A integrins in transformation by v-src
Authors: Sakai, T Jove, R Fassler, R Mosher, DF
Citation: T. Sakai et al., Role of the cytoplasmic tyrosines of beta 1A integrins in transformation by v-src, P NAS US, 98(7), 2001, pp. 3808-3813
Stat3-mediated Myc expression is required for Src transformation and PDGF-induced mitogenesis
Authors: Bowman, T Broome, MA Sinibaldi, D Wharton, W Pledger, WJ Sedivy, JM Irby, R Yeatman, T Courtneidge, SA Jove, R
Citation: T. Bowman et al., Stat3-mediated Myc expression is required for Src transformation and PDGF-induced mitogenesis, P NAS US, 98(13), 2001, pp. 7319-7324
Cooperative regulation of Mcl-1 by Janus kinase/STAT and phosphatidylinositol 3-kinase contribute to granulocyte-macrophage colony-stimulating factor-delayed apoptosis in human neutrophils
Authors: Epling-Burnette, PK Zhong, B Bai, FQ Jiang, K Bailey, RD Garcia, R Jove, R Djeu, JY Loughran, TP Wei, S
Citation: Pk. Epling-burnette et al., Cooperative regulation of Mcl-1 by Janus kinase/STAT and phosphatidylinositol 3-kinase contribute to granulocyte-macrophage colony-stimulating factor-delayed apoptosis in human neutrophils, J IMMUNOL, 166(12), 2001, pp. 7486-7495
Inhibition of STAT3 signaling leads to apoptosis of leukemic large granular lymphocytes and decreased Mcl-1 expression
Authors: Epling-Burnette, PK Liu, JH Catlett-Falcone, R Turkson, J Oshiro, M Kothapalli, R Li, YX Wang, JM Yang-Yen, HF Karras, J Jove, R Loughran, TP
Citation: Pk. Epling-burnette et al., Inhibition of STAT3 signaling leads to apoptosis of leukemic large granular lymphocytes and decreased Mcl-1 expression, J CLIN INV, 107(3), 2001, pp. 351-361
Phosphotyrosyl peptides block Stat3-mediated DNA binding activity, gene regulation, and cell transformation
Authors: Turkson, J Ryan, D Kim, JS Zhang, Y Chen, Z Haura, E Laudano, A Sebti, S Hamilton, AD Jove, R
Citation: J. Turkson et al., Phosphotyrosyl peptides block Stat3-mediated DNA binding activity, gene regulation, and cell transformation, J BIOL CHEM, 276(48), 2001, pp. 45443-45455
Overexpression of a dominant-negative signal transducer and activator of transcription 3 variant in tumor cells leads to production of soluble factors that induce apoptosis and cell cycle arrest
Authors: Niu, GL Shain, KH Huang, M Ravi, R Bedi, A Dalton, WS Jove, R Yu, H
Citation: Gl. Niu et al., Overexpression of a dominant-negative signal transducer and activator of transcription 3 variant in tumor cells leads to production of soluble factors that induce apoptosis and cell cycle arrest, CANCER RES, 61(8), 2001, pp. 3276-3280
AKT1/PKB alpha kinase is frequently elevated in human cancers and its constitutive activation is required for oncogenic transformation in NIH3T3 cells
Authors: Sun, M Wang, G Paciga, JE Feldman, RI Yuan, ZQ Ma, XL Shelley, SA Jove, R Tsichlis, PN Nicosia, SV Cheng, JQ
Citation: M. Sun et al., AKT1/PKB alpha kinase is frequently elevated in human cancers and its constitutive activation is required for oncogenic transformation in NIH3T3 cells, AM J PATH, 159(2), 2001, pp. 431-437
STAT proteins: novel molecular targets for cancer drug discovery
Authors: Turkson, J Jove, R
Citation: J. Turkson et R. Jove, STAT proteins: novel molecular targets for cancer drug discovery, ONCOGENE, 19(56), 2000, pp. 6613-6626
Induction of p21(WAF1/CIP1) and cyclin D1 expression by the Src oncoprotein in mouse fibroblasts: Role of activated STAT3 signaling
Authors: Sinibaldi, D Wharton, W Turkson, J Bowman, T Pledger, WJ Jove, R
Citation: D. Sinibaldi et al., Induction of p21(WAF1/CIP1) and cyclin D1 expression by the Src oncoprotein in mouse fibroblasts: Role of activated STAT3 signaling, ONCOGENE, 19(48), 2000, pp. 5419-5427
Preface: STAT signaling
Authors: Jove, R
Citation: R. Jove, Preface: STAT signaling, ONCOGENE, 19(21), 2000, pp. 2466-2467
STATs in oncogenesis
Authors: Bowman, T Garcia, R Turkson, J Jove, R
Citation: T. Bowman et al., STATs in oncogenesis, ONCOGENE, 19(21), 2000, pp. 2474-2488
Activation of Stat3 preassembled with platelet-derived growth factor beta receptors requires Src kinase activity
Authors: Wang, YZ Wharton, W Garcia, R Kraker, A Jove, R Pledger, WU
Citation: Yz. Wang et al., Activation of Stat3 preassembled with platelet-derived growth factor beta receptors requires Src kinase activity, ONCOGENE, 19(17), 2000, pp. 2075-2085
Activation of Stat3 in v-Src-transformed fibroblasts requires cooperation of Jak1 kinase activity
Authors: Zhang, Y Turkson, J Carter-Su, C Smithgall, T Levitzki, A Kraker, A Krolewski, JJ Medveczky, P Jove, R
Citation: Y. Zhang et al., Activation of Stat3 in v-Src-transformed fibroblasts requires cooperation of Jak1 kinase activity, J BIOL CHEM, 275(32), 2000, pp. 24935-24944
The pyrido[2,3-d]pyrimidine derivative PD180970 inhibits p210(Bcr-Abl) tyrosine kinase and induces apoptosis of K562 leukemic cells
Authors: Dorsey, JF Jove, R Kraker, AJ Wu, J
Citation: Jf. Dorsey et al., The pyrido[2,3-d]pyrimidine derivative PD180970 inhibits p210(Bcr-Abl) tyrosine kinase and induces apoptosis of K562 leukemic cells, CANCER RES, 60(12), 2000, pp. 3127-3131
Constitutive activation of Stat3 signaling confers resistance to apoptosisin human U266 myeloma cells
Authors: Catlett-Falcone, R Landowski, TH Oshiro, MM Turkson, J Levitzki, A Savino, R Ciliberto, G Moscinski, L Fernandez-Luna, JL Nunez, G Dalton, WS Jove, R
Citation: R. Catlett-falcone et al., Constitutive activation of Stat3 signaling confers resistance to apoptosisin human U266 myeloma cells, IMMUNITY, 10(1), 1999, pp. 105-115
Activating SRC mutation in a subset of advanced human colon cancers
Authors: Irby, RB Mao, WG Coppola, D Kang, J Loubeau, JM Trudeau, W Karl, R Fujita, DJ Jove, R Yeatman, TJ
Citation: Rb. Irby et al., Activating SRC mutation in a subset of advanced human colon cancers, NAT GENET, 21(2), 1999, pp. 187-190
Inhibition of pp60(c-Src) reduces Bcl-X-L expression and reverses the transformed phenotype of cells overexpressing EGF and HER-2 receptors
Authors: Karni, R Jove, R Levitzki, A
Citation: R. Karni et al., Inhibition of pp60(c-Src) reduces Bcl-X-L expression and reverses the transformed phenotype of cells overexpressing EGF and HER-2 receptors, ONCOGENE, 18(33), 1999, pp. 4654-4662
The Src-family kinase Lck can induce STAT3 phosphorylation and DNA bindingactivity
Authors: Lund, TC Coleman, C Horvath, E Sefton, BM Jove, R Medveczky, MM Medveczky, PG
Citation: Tc. Lund et al., The Src-family kinase Lck can induce STAT3 phosphorylation and DNA bindingactivity, CELL SIGNAL, 11(11), 1999, pp. 789-796
Requirement for Ras/Rac1-mediated p38 and c-Jun N-terminal kinase signaling in Stat3 transcriptional activity induced by the Src oncoprotein
Authors: Turkson, J Bowman, T Adnane, J Zhang, Y Djeu, JY Sekharam, M Frank, DA Holzman, LB Wu, J Sebti, S Jove, R
Citation: J. Turkson et al., Requirement for Ras/Rac1-mediated p38 and c-Jun N-terminal kinase signaling in Stat3 transcriptional activity induced by the Src oncoprotein, MOL CELL B, 19(11), 1999, pp. 7519-7528
Gene therapy with dominant-negative Stat3 suppresses growth of the murine melanoma B16 tumor in vivo
Authors: Niu, GL Heller, R Catlett-Falcone, R Coppola, D Jaroszeski, M Dalton, W Jove, R Yu, H
Citation: Gl. Niu et al., Gene therapy with dominant-negative Stat3 suppresses growth of the murine melanoma B16 tumor in vivo, CANCER RES, 59(20), 1999, pp. 5059-5063
STAT5 activation by BCR-Abl contributes to transformation of K562 leukemiacells
Authors: de Groot, RP Raaijmakers, JAM Lammers, JWJ Jove, R Koenderman, L
Citation: Rp. De Groot et al., STAT5 activation by BCR-Abl contributes to transformation of K562 leukemiacells, BLOOD, 94(3), 1999, pp. 1108-1112
Constitutive activation of the JAK2/STAT5 signal transduction pathway correlates with growth factor independence of megakaryocytic leukemic cell lines
Authors: Liu, RY Fan, C Garcia, R Jove, R Zuckerman, KS
Citation: Ry. Liu et al., Constitutive activation of the JAK2/STAT5 signal transduction pathway correlates with growth factor independence of megakaryocytic leukemic cell lines, BLOOD, 93(7), 1999, pp. 2369-2379
Risultati: 1-23 |