Authors:
BOSCHELLI DH
WU ZP
KLUTCHKO SR
SHOWALTER HDH
HAMBY JM
LU GH
MAJOR TC
DAHRING TK
BATLEY B
PANEK RL
KEISER J
HARTL BG
KRAKER AJ
KLOHS WD
ROBERTS BJ
PATMORE S
ELLIOTT WL
STEINKAMPF R
BRADFORD LA
HALLAK H
DOHERTY AM
Citation: Dh. Boschelli et al., SYNTHESIS AND TYROSINE KINASE INHIBITORY ACTIVITY OF A SERIES OF 2-AMINO-8H-PYRIDO[2,3-D]PYRIMIDINES - IDENTIFICATION OF POTENT, SELECTIVE PLATELET-DERIVED GROWTH-FACTOR RECEPTOR TYROSINE KINASE INHIBITORS, Journal of medicinal chemistry, 41(22), 1998, pp. 4365-4377
Authors:
KLUTCHKO SR
HAMBY JM
BOSCHELLI DH
WU ZP
KRAKER AJ
AMAR AM
HARTL BG
SHEN C
KLOHS WD
STEINKAMPF RW
DRISCOLL DL
NELSON JM
ELLIOTT WL
ROBERTS BJ
STONER CL
VINCENT PW
DYKES DJ
PANEK RL
LU GH
MAJOR TC
DAHRING TK
HALLAK H
BRADFORD LA
SHOWALTER HDH
DOHERTY AM
Citation: Sr. Klutchko et al., 2-SUBSTITUTED AMINOPYRIDO[2,3-D]PYRIMIDIN-7(8H) ONES - STRUCTURE-ACTIVITY-RELATIONSHIPS AGAINST SELECTED TYROSINE KINASES AND IN-VITRO AND IN-VIVO ANTICANCER ACTIVITY, Journal of medicinal chemistry, 41(17), 1998, pp. 3276-3292
Authors:
BARKSDALE CM
BURGER PJ
NORDBLOM GD
COOK JA
KIRKISH LS
MICHNIEWICZ BM
DUDECK RC
HODGES JC
KLUTCHKO SR
CONNOLLY CJC
Citation: Cm. Barksdale et al., DEVELOPMENT AND VALIDATION OF A RADIOIMMUNOASSAY FOR THE ORALLY-ACTIVE RENIN INHIBITOR CI-992 IN CYNOMOLGUS MONKEY AND HUMAN PLASMA, Journal of clinical ligand assay, 20(3), 1997, pp. 251-257
Authors:
PANEK RL
LU GH
KLUTCHKO SR
BATLEY BL
DAHRING TK
HAMBY JM
HALLAK H
DOHERTY AM
KEISER JA
Citation: Rl. Panek et al., IN-VITRO PHARMACOLOGICAL CHARACTERIZATION OF PD-166285, A NEW NANOMOLAR POTENT AND BROADLY ACTIVE PROTEIN-TYROSINE KINASE INHIBITOR, The Journal of pharmacology and experimental therapeutics, 283(3), 1997, pp. 1433-1444