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Results: 1-13 |
Results: 13
PREPARATION OF ALPHA-KETO ESTER ENOL ACETATES AS POTENTIAL PRODRUGS OF HUMAN NEUTROPHIL ELASTASE INHIBITORS
Authors: BURKHART JP MEHDI S KOEHL JR ANGELASTRO MR BEY P PEET NP
Citation: Jp. Burkhart et al., PREPARATION OF ALPHA-KETO ESTER ENOL ACETATES AS POTENTIAL PRODRUGS OF HUMAN NEUTROPHIL ELASTASE INHIBITORS, Bioorganic & medicinal chemistry letters, 8(1), 1998, pp. 63-64
6-HOUR WINDOW OF OPPORTUNITY FOR CALPAIN INHIBITION IN FOCAL CEREBRAL-ISCHEMIA IN RATS
Authors: MARKGRAF CG VELAYO NL JOHNSON MP MCCARTY DR MEDHI S KOEHL JR CHMIELEWSKI PA LINNIK MD
Citation: Cg. Markgraf et al., 6-HOUR WINDOW OF OPPORTUNITY FOR CALPAIN INHIBITION IN FOCAL CEREBRAL-ISCHEMIA IN RATS, Stroke, 29(1), 1998, pp. 152-158
INHIBITION OF HUMAN NEUTROPHIL ELASTASE - 4 - DESIGN, SYNTHESIS, X-RAY CRYSTALLOGRAPHIC ANALYSIS, AND STRUCTURE-ACTIVITY-RELATIONSHIPS FOR A SERIES OF P-2-MODIFIED, ORALLY-ACTIVE PEPTIDYL PENTAFLUOROETHYL KETONES
Authors: CREGGE RJ DURHAM SL FARR RA GALLION SL HARE CM HOFFMAN RV JANUSZ MJ KIM HO KOEHL JR MEHDI S METZ WA PEET NP PELTON JT SCHREUDER HA SUNDER S TARDIF C
Citation: Rj. Cregge et al., INHIBITION OF HUMAN NEUTROPHIL ELASTASE - 4 - DESIGN, SYNTHESIS, X-RAY CRYSTALLOGRAPHIC ANALYSIS, AND STRUCTURE-ACTIVITY-RELATIONSHIPS FOR A SERIES OF P-2-MODIFIED, ORALLY-ACTIVE PEPTIDYL PENTAFLUOROETHYL KETONES, Journal of medicinal chemistry, 41(14), 1998, pp. 2461-2480
CALPAIN INHIBITION PROTECTS NEURONS WHEN THERAPY IS DELAYED FOR 6 HOURS AFTER FOCAL CEREBRAL-ISCHEMIA
Authors: JOHNSON MP MARKGRAF CG VELAYO NL MCCARTY DR CHMIELEWSKI PA KOEHL JR MEHDI S ANGELASTRO MR LINNIK MD
Citation: Mp. Johnson et al., CALPAIN INHIBITION PROTECTS NEURONS WHEN THERAPY IS DELAYED FOR 6 HOURS AFTER FOCAL CEREBRAL-ISCHEMIA, Stroke, 28(1), 1997, pp. 115-115
THE SYNTHESIS OF AMINOBENZAZEPINONES AS ANTI-PHENYLALANINE DIPEPTIDE MIMICS AND THEIR USE IN NEP INHIBITION
Authors: WARSHAWSKY AM FLYNN GA KOEHL JR MEHDI S VAZ RJ
Citation: Am. Warshawsky et al., THE SYNTHESIS OF AMINOBENZAZEPINONES AS ANTI-PHENYLALANINE DIPEPTIDE MIMICS AND THEIR USE IN NEP INHIBITION, Bioorganic & medicinal chemistry letters, 6(8), 1996, pp. 957-962
SYNTHESIS OF CONSTRAINED THIORPHAN ANALOGS AS INHIBITORS OF NEUTRAL ENDOPEPTIDASE
Authors: BEIGHT DW MEHDI S KOEHL JR FLYNN GA
Citation: Dw. Beight et al., SYNTHESIS OF CONSTRAINED THIORPHAN ANALOGS AS INHIBITORS OF NEUTRAL ENDOPEPTIDASE, Bioorganic & medicinal chemistry letters, 6(17), 1996, pp. 2053-2058
INHIBITION OF HUMAN NEUTROPHIL ELASTASE .3. AN ORALLY-ACTIVE ENOL ACETATE PRODRUG
Authors: BURKHART JP KOEHL JR MEHDI S DURHAM SL JANUSZ MJ HUBER EW ANGELASTRO MR SUNDER S METZ WA SHUM PW CHEN TM BEY P CREGGE RJ PEET NP
Citation: Jp. Burkhart et al., INHIBITION OF HUMAN NEUTROPHIL ELASTASE .3. AN ORALLY-ACTIVE ENOL ACETATE PRODRUG, Journal of medicinal chemistry, 38(2), 1995, pp. 223-233
PHARMACOLOGY OF FLUORO-1-(1-METHYLETHYL)-2-OXOBUTYL]-L-PROLINAMIDE (MDL-101,146) - A POTENT ORALLY-ACTIVE INHIBITOR OF HUMAN NEUTROPHIL ELASTASE (VOL 270, PG 185, 1994)
Authors: DURHAM SL HARE CM ANGELASTRO MR BURKHART JP KOEHL JR MARQUART AL MEHDI S PEET NP JANUSZ MJ
Citation: Sl. Durham et al., PHARMACOLOGY OF FLUORO-1-(1-METHYLETHYL)-2-OXOBUTYL]-L-PROLINAMIDE (MDL-101,146) - A POTENT ORALLY-ACTIVE INHIBITOR OF HUMAN NEUTROPHIL ELASTASE (VOL 270, PG 185, 1994), The Journal of pharmacology and experimental therapeutics, 271(3), 1994, pp. 1720-1720
PHARMACOLOGY OF FLUORO-1-(1-METHYLETHYL)-2-OXOBUTYL]-L-PROLINAMIDE (MDL-101,146) - A POTENT ORALLY-ACTIVE INHIBITOR OF HUMAN NEUTROPHIL ELASTASE
Authors: DURHAM SL HARE CM ANGELASTRO MR BURKHART JP KOEHL JR MARQUART AL MEHDI S FEET NP JANUSZ MJ
Citation: Sl. Durham et al., PHARMACOLOGY OF FLUORO-1-(1-METHYLETHYL)-2-OXOBUTYL]-L-PROLINAMIDE (MDL-101,146) - A POTENT ORALLY-ACTIVE INHIBITOR OF HUMAN NEUTROPHIL ELASTASE, The Journal of pharmacology and experimental therapeutics, 270(1), 1994, pp. 185-191
CHARACTERIZATION OF A DUAL INHIBITOR OF ANGIOTENSIN I-CONVERTING ENZYME AND NEUTRAL ENDOPEPTIDASE
Authors: FRENCH JF FLYNN GA GIROUX EL MEHDI S ANDERSON B BEACH DC KOEHL JR DAGE RC
Citation: Jf. French et al., CHARACTERIZATION OF A DUAL INHIBITOR OF ANGIOTENSIN I-CONVERTING ENZYME AND NEUTRAL ENDOPEPTIDASE, The Journal of pharmacology and experimental therapeutics, 268(1), 1994, pp. 180-186
INHIBITION OF HUMAN NEUTROPHIL ELASTASE WITH PEPTIDYL ELECTROPHILIC KETONES .2. ORALLY-ACTIVE P-G-VAL-PRO-VAL PENTAFLUOROETHYL KETONES
Authors: ANGELASTRO MR BAUGH LE BEY P BURKHART JP CHEN TM DURHAM SL HARE CM HUBER EW JANUSZ MJ KOEHL JR MARQUART AL MEHDI S PEET NP
Citation: Mr. Angelastro et al., INHIBITION OF HUMAN NEUTROPHIL ELASTASE WITH PEPTIDYL ELECTROPHILIC KETONES .2. ORALLY-ACTIVE P-G-VAL-PRO-VAL PENTAFLUOROETHYL KETONES, Journal of medicinal chemistry, 37(26), 1994, pp. 4538-4553
APPLICATION OF A CONFORMATIONALLY RESTRICTED PHE-LEU DIPEPTIDE MIMETIC TO THE DESIGN OF A COMBINED INHIBITOR OF ANGIOTENSIN I-CONVERTING ENZYME AND NEUTRAL ENDOPEPTIDASE-24.11
Authors: FLYNN GA BEIGHT DW MEHDI S KOEHL JR GIROUX EL FRENCH JF HAKE PW DAGE RC
Citation: Ga. Flynn et al., APPLICATION OF A CONFORMATIONALLY RESTRICTED PHE-LEU DIPEPTIDE MIMETIC TO THE DESIGN OF A COMBINED INHIBITOR OF ANGIOTENSIN I-CONVERTING ENZYME AND NEUTRAL ENDOPEPTIDASE-24.11, Journal of medicinal chemistry, 36(16), 1993, pp. 2420-2423
MDL 101,146, A POTENT ORALLY ACTIVE INHIBITOR OF HUMAN NEUTROPHIL ELASTASE INDUCED ACUTE PULMONARY HEMORRHAGE IN RATS AND HAMSTERS
Authors: DURHAM SL HARE CM ANGELASTRO MR BURKHART JP KOEHL JR MARQUART AL MEHDI S PEET NP JANUSZ MJ
Citation: Sl. Durham et al., MDL 101,146, A POTENT ORALLY ACTIVE INHIBITOR OF HUMAN NEUTROPHIL ELASTASE INDUCED ACUTE PULMONARY HEMORRHAGE IN RATS AND HAMSTERS, The American review of respiratory disease, 147(4), 1993, pp. 675-675
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