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Results: 1-7 |
Results: 7
MICROSOMAL METABOLISM OF DELAVIRDINE - EVIDENCE FOR MECHANISM-BASED INACTIVATION OF HUMAN CYTOCHROME-P450 3A
Authors: VOORMAN RL MAIO SM PAYNE NA ZHA ZY KOEPLINGER KA WANG XH
Citation: Rl. Voorman et al., MICROSOMAL METABOLISM OF DELAVIRDINE - EVIDENCE FOR MECHANISM-BASED INACTIVATION OF HUMAN CYTOCHROME-P450 3A, The Journal of pharmacology and experimental therapeutics, 287(1), 1998, pp. 381-388
CONTRIBUTION OF SERUM-PROTEIN ASSOCIATION TO DISCREPANCY BETWEEN THE IN-VIVO AND IN-VITRO UDS RESULTS FOR -2,4-DI-1-PYRROLIDINYL-7H-PYRROLO[2,3-D]PYRIMIDINE (U-89843)
Authors: ZHAO ZY KOEPLINGER KA PADBURY GE AARON CS HARBACH PR MAYO JK MATTES WB BUNDY GL
Citation: Zy. Zhao et al., CONTRIBUTION OF SERUM-PROTEIN ASSOCIATION TO DISCREPANCY BETWEEN THE IN-VIVO AND IN-VITRO UDS RESULTS FOR -2,4-DI-1-PYRROLIDINYL-7H-PYRROLO[2,3-D]PYRIMIDINE (U-89843), Mutation research. Genetic toxicology and environmental mutagenesis, 395(2-3), 1997, pp. 119-126
BIOACTIVATION OF -2,4-DI-1-PYRROLIDINYL-7H-PYRROLO[2,3-D]PYRIMIDINE (U-89843) TO REACTIVE INTERMEDIATES THAT BIND COVALENTLY TO MACROMOLECULES AND PRODUCE GENOTOXICITY
Authors: ZHAO ZY KOEPLINGER KA PADBURY GE HAUER MJ BUNDY GL BANITT LS SCHWARTZ TM ZIMMERMANN DC HARBACH PR MAYO JK AARON CS
Citation: Zy. Zhao et al., BIOACTIVATION OF -2,4-DI-1-PYRROLIDINYL-7H-PYRROLO[2,3-D]PYRIMIDINE (U-89843) TO REACTIVE INTERMEDIATES THAT BIND COVALENTLY TO MACROMOLECULES AND PRODUCE GENOTOXICITY, Chemical research in toxicology, 9(8), 1996, pp. 1230-1239
IN-VITRO AND IN-VIVO BIOTRANSFORMATION OF -2,4-DI-1-PYRROLIDINYL-7H-PYRROLO[2,3-D]PYRIMIDINE (U-89843) IN THE RAT
Authors: ZHAO ZY KOEPLINGER KA BUNDY GL BANITT LS PADBURY GE HAUER MJ SANDERS PE
Citation: Zy. Zhao et al., IN-VITRO AND IN-VIVO BIOTRANSFORMATION OF -2,4-DI-1-PYRROLIDINYL-7H-PYRROLO[2,3-D]PYRIMIDINE (U-89843) IN THE RAT, Drug metabolism and disposition, 24(2), 1996, pp. 187-198
STRUCTURE-BASED DESIGN OF HIV PROTEASE INHIBITORS - SULFONAMIDE-CONTAINING 5,6-DIHYDRO-4-HYDROXY-2-PYRONES AS NONPEPTIDIC INHIBITORS
Authors: THAISRIVONGS S SKULNICK HI TURNER SR STROHBACH JW TOMMASI RA JOHNSON PD ARISTOFF PA JUDGE TM GAMMILL RB MORRIS JK ROMINES KR CHRUSCIEL RA HINSHAW RR CHONG KT TARPLEY WG POPPE SM SLADE DE LYNN JC HORNG MM TOMICH PK SEEST EP DOLAK LA HOWE WJ HOWARD GM SCHWENDE FJ TOTH LN PADBURY GE WILSON GJ SHIOU LH ZIPP GL WILKINSON KF RUSH BD RUWART MJ KOEPLINGER KA ZHAO ZY COLE S ZAYA RM KAKUK TJ JANAKIRAMAN MN WATENPAUGH KD
Citation: S. Thaisrivongs et al., STRUCTURE-BASED DESIGN OF HIV PROTEASE INHIBITORS - SULFONAMIDE-CONTAINING 5,6-DIHYDRO-4-HYDROXY-2-PYRONES AS NONPEPTIDIC INHIBITORS, Journal of medicinal chemistry, 39(22), 1996, pp. 4349-4353
CHROMATOGRAPHIC MEASUREMENT OF DRUG-PROTEIN INTERACTION - DETERMINATION OF HIV PROTEASE INHIBITOR-SERUM ALBUMIN ASSOCIATION
Authors: KOEPLINGER KA ZHAO ZY
Citation: Ka. Koeplinger et Zy. Zhao, CHROMATOGRAPHIC MEASUREMENT OF DRUG-PROTEIN INTERACTION - DETERMINATION OF HIV PROTEASE INHIBITOR-SERUM ALBUMIN ASSOCIATION, Analytical biochemistry, 243(1), 1996, pp. 66-73
STRUCTURE-BASED DESIGN OF HIV PROTEASE INHIBITORS - 4-HYDROXYCOUMARINS AND 4-HYDROXY-2-PYRONES AS NONPEPTIDIC INHIBITORS
Authors: THAISRIVONGS S TOMICH PK WATENPAUGH KD CHONG KT HOWE WJ YANG CP STROHBACH JW TURNER SR MCGRATH JP BOHANON MJ LYNN JC MULICHAK AM SPINELLI PA HINSHAW RR PAGANO PJ MOON JB RUWART MJ WILKINSON KF RUSH BD ZIPP GL DALGA RJ SCHWENDE FJ HOWARD GM PADBURY GE TOTH LN ZHAO ZY KOEPLINGER KA KAKUK TJ COLE SL ZAYA RM PIPER RC JEFFREY P
Citation: S. Thaisrivongs et al., STRUCTURE-BASED DESIGN OF HIV PROTEASE INHIBITORS - 4-HYDROXYCOUMARINS AND 4-HYDROXY-2-PYRONES AS NONPEPTIDIC INHIBITORS, Journal of medicinal chemistry, 37(20), 1994, pp. 3200-3204
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