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Results: 1-22 |
Results: 22
PROTEIN-LINKED DNA STRAND BREAKS INDUCED BY NSC-314622, A NOVEL NONCAMPTOTHECIN TOPOISOMERASE-I POISON
Authors: KOHLHAGEN G PAULL KD CUSHMAN M NAGAFUJI P POMMIER Y
Citation: G. Kohlhagen et al., PROTEIN-LINKED DNA STRAND BREAKS INDUCED BY NSC-314622, A NOVEL NONCAMPTOTHECIN TOPOISOMERASE-I POISON, Molecular pharmacology, 54(1), 1998, pp. 50-58
EARLY INDUCTION OF APOPTOSIS IN HEMATOPOIETIC-CELL LINES AFTER EXPOSURE TO FLAVOPIRIDOL
Authors: PARKER BW KAUR G NIEVESNEIRA W TAIMI M KOHLHAGEN G SHIMIZU T LOSIEWICZ MD POMMIER Y SAUSVILLE EA SENDEROWICZ AM
Citation: Bw. Parker et al., EARLY INDUCTION OF APOPTOSIS IN HEMATOPOIETIC-CELL LINES AFTER EXPOSURE TO FLAVOPIRIDOL, Blood, 91(2), 1998, pp. 458-465
MAMMALIAN DNA TOPOISOMERASE-I ACTIVITY AND POISONING BY CAMPTOTHECIN ARE INHIBITED BY SIMIAN-VIRUS-40 LARGE T-ANTIGEN
Authors: POMMIER Y KOHLHAGEN G WU CX SIMMONS DT
Citation: Y. Pommier et al., MAMMALIAN DNA TOPOISOMERASE-I ACTIVITY AND POISONING BY CAMPTOTHECIN ARE INHIBITED BY SIMIAN-VIRUS-40 LARGE T-ANTIGEN, Biochemistry, 37(11), 1998, pp. 3818-3823
NOVEL 7-ALKYL METHYLENEDIOXY-CAMPTOTHECIN DERIVATIVES EXHIBIT INCREASED CYTOTOXICITY AND INDUCE PERSISTENT CLEAVABLE COMPLEXES BOTH WITH PURIFIED MAMMALIAN TOPOISOMERASE-I AND IN HUMAN COLON-CARCINOMA SW620 CELLS
Authors: VALENTI M NIEVESNEIRA W KOHLHAGEN G KOHN KW WALL ME WANI MC POMMIER Y
Citation: M. Valenti et al., NOVEL 7-ALKYL METHYLENEDIOXY-CAMPTOTHECIN DERIVATIVES EXHIBIT INCREASED CYTOTOXICITY AND INDUCE PERSISTENT CLEAVABLE COMPLEXES BOTH WITH PURIFIED MAMMALIAN TOPOISOMERASE-I AND IN HUMAN COLON-CARCINOMA SW620 CELLS, Molecular pharmacology, 52(1), 1997, pp. 82-87
TRAPPING OF MAMMALIAN TOPOISOMERASE-I AND RECOMBINATIONS INDUCED BY DAMAGED DNA CONTAINING NICKS OR GAPS - IMPORTANCE OF DNA END PHOSPHORYLATION AND CAMPTOTHECIN EFFECTS
Authors: POURQUIER P PILON AA KOHLHAGEN G MAZUMDER A SHARMA A POMMIER Y
Citation: P. Pourquier et al., TRAPPING OF MAMMALIAN TOPOISOMERASE-I AND RECOMBINATIONS INDUCED BY DAMAGED DNA CONTAINING NICKS OR GAPS - IMPORTANCE OF DNA END PHOSPHORYLATION AND CAMPTOTHECIN EFFECTS, The Journal of biological chemistry, 272(42), 1997, pp. 26441-26447
EFFECTS OF URACIL INCORPORATION, DNA MISMATCHES, AND ABASIC SITES ON CLEAVAGE AND RELIGATION ACTIVITIES OF MAMMALIAN TOPOISOMERASE-I
Authors: POURQUIER P UENG LM KOHLHAGEN G MAZUMDER A GUPTA M KOHN KW POMMIER Y
Citation: P. Pourquier et al., EFFECTS OF URACIL INCORPORATION, DNA MISMATCHES, AND ABASIC SITES ON CLEAVAGE AND RELIGATION ACTIVITIES OF MAMMALIAN TOPOISOMERASE-I, The Journal of biological chemistry, 272(12), 1997, pp. 7792-7796
DNA SEQUENCE-SELECTIVE AND STRUCTURE-SELECTIVE ALKYLATION OF GUANINE N2 IN THE DNA MINOR-GROOVE BY ECTEINASCIDIN-743, A POTENT ANTITUMOR COMPOUND FROM THE CARIBBEAN TUNICATE ECTEINASCIDIN-TURBINATA
Authors: POMMIER Y KOHLHAGEN G BAILLY C WARING M MAZUMDER A KOHN KW
Citation: Y. Pommier et al., DNA SEQUENCE-SELECTIVE AND STRUCTURE-SELECTIVE ALKYLATION OF GUANINE N2 IN THE DNA MINOR-GROOVE BY ECTEINASCIDIN-743, A POTENT ANTITUMOR COMPOUND FROM THE CARIBBEAN TUNICATE ECTEINASCIDIN-TURBINATA, Biochemistry, 35(41), 1996, pp. 13303-13309
DNA RECOMBINASE ACTIVITY OF EUKARYOTIC DNA TOPOISOMERASE-I - EFFECTS OF CAMPTOTHECIN AND OTHER INHIBITORS
Authors: POMMIER Y JENKINS J KOHLHAGEN G LETEURTRE F
Citation: Y. Pommier et al., DNA RECOMBINASE ACTIVITY OF EUKARYOTIC DNA TOPOISOMERASE-I - EFFECTS OF CAMPTOTHECIN AND OTHER INHIBITORS, Mutation research. DNA repair, 337(2), 1995, pp. 135-145
INTERACTION OF AN ALKYLATING CAMPTOTHECIN DERIVATIVE WITH A DNA-BASE AT TOPOISOMERASE I-DNA CLEAVAGE SITES
Authors: POMMIER Y KOHLHAGEN G KOHN KW LETEURTRE F WANI MC WALL ME
Citation: Y. Pommier et al., INTERACTION OF AN ALKYLATING CAMPTOTHECIN DERIVATIVE WITH A DNA-BASE AT TOPOISOMERASE I-DNA CLEAVAGE SITES, Proceedings of the National Academy of Sciences of the United Statesof America, 92(19), 1995, pp. 8861-8865
EUKARYOTIC DNA TOPOISOMERASES MEDIATED DNA CLEAVAGE INDUCED BY A NEW INHIBITOR - NSC-665517
Authors: GUPTA M ABDELMEGEED M HOKI Y KOHLHAGEN G PAULL K POMMIER Y
Citation: M. Gupta et al., EUKARYOTIC DNA TOPOISOMERASES MEDIATED DNA CLEAVAGE INDUCED BY A NEW INHIBITOR - NSC-665517, Molecular pharmacology, 48(4), 1995, pp. 658-665
MUTATION AT THE CATALYTIC SITE OF TOPOISOMERASE-I IN CEM C2, A HUMAN LEUKEMIA-CELL LINE RESISTANT TO CAMPTOTHECIN/
Authors: FUJIMORI A HARKER WG KOHLHAGEN G HOKI Y POMMIER Y
Citation: A. Fujimori et al., MUTATION AT THE CATALYTIC SITE OF TOPOISOMERASE-I IN CEM C2, A HUMAN LEUKEMIA-CELL LINE RESISTANT TO CAMPTOTHECIN/, Cancer research, 55(6), 1995, pp. 1339-1346
EFFECTS OF TYRPHOSTINS, PROTEIN-KINASE INHIBITORS, ON HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 INTEGRASE
Authors: MAZUMDER A GAZIT A LEVITZKI A NICKLAUS M YUNG J KOHLHAGEN G POMMIER Y
Citation: A. Mazumder et al., EFFECTS OF TYRPHOSTINS, PROTEIN-KINASE INHIBITORS, ON HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 INTEGRASE, Biochemistry, 34(46), 1995, pp. 15111-15122
DIFFERENTIAL STABILIZATION OF EUKARYOTIC DNA TOPOISOMERASE-I CLEAVABLE COMPLEXES BY CAMPTOTHECIN DERIVATIVES
Authors: TANIZAWA A KOHN KW KOHLHAGEN G LETEURTRE F POMMIER Y
Citation: A. Tanizawa et al., DIFFERENTIAL STABILIZATION OF EUKARYOTIC DNA TOPOISOMERASE-I CLEAVABLE COMPLEXES BY CAMPTOTHECIN DERIVATIVES, Biochemistry, 34(21), 1995, pp. 7200-7206
AZATOXIN DERIVATIVES WITH POTENT AND SELECTIVE ACTION ON TOPOISOMERASE-II
Authors: LETEURTRE F SACKETT DL MADALENGOITIA J KOHLHAGEN G MACDONALD T HAMEL E PAULL KD POMMIER Y
Citation: F. Leteurtre et al., AZATOXIN DERIVATIVES WITH POTENT AND SELECTIVE ACTION ON TOPOISOMERASE-II, Biochemical pharmacology, 49(9), 1995, pp. 1283-1290
TOPOISOMERASE INHIBITION AND CYTOTOXICITY OF THE ANTHRAPYRAZOLES DUP-937 AND DUP-941 (LOSOXANTRONE) IN THE NATIONAL-CANCER-INSTITUTE PRECLINICAL ANTITUMOR DRUG DISCOVERY SCREEN
Authors: LETEURTRE F KOHLHAGEN G PAULL KD POMMIER Y
Citation: F. Leteurtre et al., TOPOISOMERASE INHIBITION AND CYTOTOXICITY OF THE ANTHRAPYRAZOLES DUP-937 AND DUP-941 (LOSOXANTRONE) IN THE NATIONAL-CANCER-INSTITUTE PRECLINICAL ANTITUMOR DRUG DISCOVERY SCREEN, Journal of the National Cancer Institute, 86(16), 1994, pp. 1239-1244
MAPPING OF TOPOISOMERASE CLEAVAGE SITES IN THE HUMAN C-MYC PROTOONCOGENE
Authors: LETEURTRE F GUPTA M KOHLHAGEN G POMMIER Y
Citation: F. Leteurtre et al., MAPPING OF TOPOISOMERASE CLEAVAGE SITES IN THE HUMAN C-MYC PROTOONCOGENE, The FASEB journal, 8(7), 1994, pp. 10001272-10001272
CELLULAR DETERMINANTS OF SENSITIVITY AND RESISTANCE TO DNA TOPOISOMERASE INHIBITORS
Authors: POMMIER Y LETEURTRE F FESEN MR FUJIMORI A BERTRAND R SOLARY E KOHLHAGEN G KOHN KW
Citation: Y. Pommier et al., CELLULAR DETERMINANTS OF SENSITIVITY AND RESISTANCE TO DNA TOPOISOMERASE INHIBITORS, Cancer investigation, 12(5), 1994, pp. 530-542
SAINTOPIN, A DUAL INHIBITOR OF DNA TOPOISOMERASE-I AND TOPOISOMERASE-II, AS A PROBE FOR DRUG-ENZYME INTERACTIONS
Authors: LETEURTRE F FUJIMORI A TANIZAWA A CHHABRA A MAZUMDER A KOHLHAGEN G NAKANO H POMMIER Y
Citation: F. Leteurtre et al., SAINTOPIN, A DUAL INHIBITOR OF DNA TOPOISOMERASE-I AND TOPOISOMERASE-II, AS A PROBE FOR DRUG-ENZYME INTERACTIONS, The Journal of biological chemistry, 269(46), 1994, pp. 28702-28707
EFFECTS OF DNA METHYLATION ON TOPOISOMERASE-I AND TOPOISOMERASE-II CLEAVAGE ACTIVITIES
Authors: LETEURTRE F KOHLHAGEN G FESEN MR TANIZAWA A KOHN KW POMMIER Y
Citation: F. Leteurtre et al., EFFECTS OF DNA METHYLATION ON TOPOISOMERASE-I AND TOPOISOMERASE-II CLEAVAGE ACTIVITIES, The Journal of biological chemistry, 269(11), 1994, pp. 7893-7900
STREPTONIGRIN-INDUCED TOPOISOMERASE-II SITES EXHIBIT BASE PREFERENCESIN THE MIDDLE OF THE ENZYME STAGGER
Authors: LETEURTRE F KOHLHAGEN G POMMIER Y
Citation: F. Leteurtre et al., STREPTONIGRIN-INDUCED TOPOISOMERASE-II SITES EXHIBIT BASE PREFERENCESIN THE MIDDLE OF THE ENZYME STAGGER, Biochemical and biophysical research communications, 203(2), 1994, pp. 1259-1267
CLONING OF CHINESE-HAMSTER DNA TOPOISOMERASE-I CDNA AND IDENTIFICATION OF A SINGLE-POINT MUTATION RESPONSIBLE FOR CAMPTOTHECIN RESISTANCE
Authors: TANIZAWA A BERTRAND R KOHLHAGEN G TABUCHI A JENKINS J POMMIER Y
Citation: A. Tanizawa et al., CLONING OF CHINESE-HAMSTER DNA TOPOISOMERASE-I CDNA AND IDENTIFICATION OF A SINGLE-POINT MUTATION RESPONSIBLE FOR CAMPTOTHECIN RESISTANCE, The Journal of biological chemistry, 268(34), 1993, pp. 25463-25468
SPECIFIC INTERACTION OF CAMPTOTHECIN, A TOPOISOMERASE-I INHIBITOR, WITH GUANINE RESIDUES OF DNA DETECTED BY PHOTOACTIVATION AT 365 NM
Authors: LETEURTRE F FESEN M KOHLHAGEN G KOHN KW POMMIER Y
Citation: F. Leteurtre et al., SPECIFIC INTERACTION OF CAMPTOTHECIN, A TOPOISOMERASE-I INHIBITOR, WITH GUANINE RESIDUES OF DNA DETECTED BY PHOTOACTIVATION AT 365 NM, Biochemistry, 32(34), 1993, pp. 8955-8962
Risultati: 1-22 |