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Results: 1-25 | 26-42
Results: 1-25/42
ROLE OF HUMAN CYTOCHROME-P450 3A4 AND 3A5 IN THE METABOLISM OF TAXOTERE AND ITS DERIVATIVES - ENZYME SPECIFICITY, INTERINDIVIDUAL DISTRIBUTION AND METABOLIC CONTRIBUTION IN HUMAN LIVER
Authors: SHOU MG MARTINET M KORZEKWA KR KRAUSZ KW GONZALEZ FJ GELBOIN HV
Citation: Mg. Shou et al., ROLE OF HUMAN CYTOCHROME-P450 3A4 AND 3A5 IN THE METABOLISM OF TAXOTERE AND ITS DERIVATIVES - ENZYME SPECIFICITY, INTERINDIVIDUAL DISTRIBUTION AND METABOLIC CONTRIBUTION IN HUMAN LIVER, Pharmacogenetics, 8(5), 1998, pp. 391-401
SELECTIVELY DEUTERATED WARFARIN - SUBSTRATE PROBE FOR THE MECHANISM OF AROMATIC HYDROXYLATION CATALYZED BY CYTOCHROME-P450
Authors: DARBYSHIRE JF IYER KR GROGAN J KORZEKWA KR TRAGER WF
Citation: Jf. Darbyshire et al., SELECTIVELY DEUTERATED WARFARIN - SUBSTRATE PROBE FOR THE MECHANISM OF AROMATIC HYDROXYLATION CATALYZED BY CYTOCHROME-P450, The FASEB journal, 12(5), 1998, pp. 5567-5567
METABOLISM OF DAPSONE BY CYP2C9 AND ITS EFFECT ON CYP2C9 SUBSTRATES
Authors: TRACY TS METZ CA KORZEKWA KR
Citation: Ts. Tracy et al., METABOLISM OF DAPSONE BY CYP2C9 AND ITS EFFECT ON CYP2C9 SUBSTRATES, Clinical pharmacology and therapeutics, 63(2), 1998, pp. 61-61
EVALUATION OF ATYPICAL CYTOCHROME-P450 KINETICS WITH 2-SUBSTRATE MODELS - EVIDENCE THAT MULTIPLE SUBSTRATES CAN SIMULTANEOUSLY BIND TO CYTOCHROME-P450 ACTIVE-SITES
Authors: KORZEKWA KR KRISHNAMACHARY N SHOU M OGAI A PARISE RA RETTIE AE GONZALEZ FJ TRACY TS
Citation: Kr. Korzekwa et al., EVALUATION OF ATYPICAL CYTOCHROME-P450 KINETICS WITH 2-SUBSTRATE MODELS - EVIDENCE THAT MULTIPLE SUBSTRATES CAN SIMULTANEOUSLY BIND TO CYTOCHROME-P450 ACTIVE-SITES, Biochemistry, 37(12), 1998, pp. 4137-4147
ROLE OF CDNA-EXPRESSED HUMAN CYTOCHROMES P450 IN THE METABOLISM OF DIAZEPAM
Authors: YANG TJ SHOU M KORZEKWA KR GONZALEZ FJ GELBOIN HV YANG SK
Citation: Tj. Yang et al., ROLE OF CDNA-EXPRESSED HUMAN CYTOCHROMES P450 IN THE METABOLISM OF DIAZEPAM, Biochemical pharmacology, 55(6), 1998, pp. 889-896
THE EFFECTS OF DIABETES ON PLACENTAL AROMATASE-ACTIVITY
Authors: MCROBIE DJ KORZEKWA KR GLOVER DD TRACY TS
Citation: Dj. Mcrobie et al., THE EFFECTS OF DIABETES ON PLACENTAL AROMATASE-ACTIVITY, Journal of steroid biochemistry and molecular biology, 63(1-3), 1997, pp. 147-153
STUDIES ON CYTOCHROME-P450 REDUCTASE INTERACTIONS
Authors: KORZEKWA KR SHOU M GROGAN J PARISE R
Citation: Kr. Korzekwa et al., STUDIES ON CYTOCHROME-P450 REDUCTASE INTERACTIONS, The FASEB journal, 11(9), 1997, pp. 11-11
FUNCTIONAL-CHARACTERIZATION OF GLU-302, SER-478, AND HIS-480 OF HUMANAROMATASE (CYP19)
Authors: KAO YC KORZEKWA KR LAUGHTON CA CHEN S
Citation: Yc. Kao et al., FUNCTIONAL-CHARACTERIZATION OF GLU-302, SER-478, AND HIS-480 OF HUMANAROMATASE (CYP19), The FASEB journal, 11(9), 1997, pp. 142-142
ROLE OF HUMAN HEPATIC CYTOCHROME-P450 1A2 AND 3A4 IN THE METABOLIC-ACTIVATION OF ESTRONE
Authors: SHOU MG KORZEKWA KR BROOKS EN KRAUSZ KW GONZALEZ FJ GELBOIN HV
Citation: Mg. Shou et al., ROLE OF HUMAN HEPATIC CYTOCHROME-P450 1A2 AND 3A4 IN THE METABOLIC-ACTIVATION OF ESTRONE, Carcinogenesis, 18(1), 1997, pp. 207-214
INVOLVEMENT OF MULTIPLE CYTOCHROME-P450 ISOFORMS IN NAPROXEN O-DEMETHYLATION
Authors: TRACY TS MARRA C WRIGHTON SA GONZALEZ FJ KORZEKWA KR
Citation: Ts. Tracy et al., INVOLVEMENT OF MULTIPLE CYTOCHROME-P450 ISOFORMS IN NAPROXEN O-DEMETHYLATION, European Journal of Clinical Pharmacology, 52(4), 1997, pp. 293-298
HUMAN CYP2C9 AND CYP2A6 MEDIATE FORMATION OF THE HEPATOTOXIN 4-ENE-VALPROIC ACID
Authors: SADEQUE AJM FISHER MB KORZEKWA KR GONZALEZ FJ RETTIE AE
Citation: Ajm. Sadeque et al., HUMAN CYP2C9 AND CYP2A6 MEDIATE FORMATION OF THE HEPATOTOXIN 4-ENE-VALPROIC ACID, The Journal of pharmacology and experimental therapeutics, 283(2), 1997, pp. 698-703
SPECIFICITY OF CDNA-EXPRESSED HUMAN AND RODENT CYTOCHROME P450S IN THE OXIDATIVE-METABOLISM OF THE POTENT CARCINOGEN 7,12-DIMETHYLBENZ[A]ANTHRACENE
Authors: SHOU MG KORZEKWA KR KRAUSZ KW BUTERS JTM GROGAN J GOLDFARB I HARDWICK JP GONZALEZ FJ GELBOIN HV
Citation: Mg. Shou et al., SPECIFICITY OF CDNA-EXPRESSED HUMAN AND RODENT CYTOCHROME P450S IN THE OXIDATIVE-METABOLISM OF THE POTENT CARCINOGEN 7,12-DIMETHYLBENZ[A]ANTHRACENE, Molecular carcinogenesis, 17(4), 1996, pp. 241-249
INHIBITORY AND NONINHIBITORY MONOCLONAL-ANTIBODIES TO HUMAN CYTOCHROME-P450 2E1
Authors: GELBOIN HV GOLDFARB I KRAUSZ KW GROGAN J KORZEKWA KR GONZALEZ FJ SHOU MG
Citation: Hv. Gelboin et al., INHIBITORY AND NONINHIBITORY MONOCLONAL-ANTIBODIES TO HUMAN CYTOCHROME-P450 2E1, Chemical research in toxicology, 9(6), 1996, pp. 1023-1030
SELECTIVELY DEUTERATED WARFARIN - SUBSTRATE PROBE FOR THE MECHANISM OF AROMATIC HYDROXYLATION CATALYZED BY CYTOCHROME-P450
Authors: DARBYSHIRE JF IYER KR GROGAN J KORZEKWA KR TRAGER WF
Citation: Jf. Darbyshire et al., SELECTIVELY DEUTERATED WARFARIN - SUBSTRATE PROBE FOR THE MECHANISM OF AROMATIC HYDROXYLATION CATALYZED BY CYTOCHROME-P450, Drug metabolism and disposition, 24(9), 1996, pp. 1038-1045
INVOLVEMENT OF MULTIPLE CYTOCHROME-P450 ISOFORMS IN NAPROXEN DEMETHYLATION
Authors: TRACY TS MARRA C WRIGHTON SA GONZALEZ FJ KORZEKWA KR
Citation: Ts. Tracy et al., INVOLVEMENT OF MULTIPLE CYTOCHROME-P450 ISOFORMS IN NAPROXEN DEMETHYLATION, Clinical pharmacology and therapeutics, 59(2), 1996, pp. 51-51
STUDIES OF FLURBIPROFEN 4'-HYDROXYLATION - ADDITIONAL EVIDENCE SUGGESTING THE SOLE INVOLVEMENT OF CYTOCHROME-P450 2C9
Authors: TRACY TS MARRA C WRIGHTON SA GONZALEZ FJ KORZEKWA KR
Citation: Ts. Tracy et al., STUDIES OF FLURBIPROFEN 4'-HYDROXYLATION - ADDITIONAL EVIDENCE SUGGESTING THE SOLE INVOLVEMENT OF CYTOCHROME-P450 2C9, Biochemical pharmacology, 52(8), 1996, pp. 1305-1309
COMPARISON OF SUBSTRATE METABOLISM BY WILD-TYPE CYP2D6 PROTEIN AND A VARIANT CONTAINING METHIONINE, NOT VALINE, AT POSITION-374
Authors: CRESPI CL STEIMEL DT PENMAN BW KORZEKWA KR FERNANDEZSALGUERO P BUTERS JTM GELBOIN HV GONZALEZ FJ IDLE JR DALY AK
Citation: Cl. Crespi et al., COMPARISON OF SUBSTRATE METABOLISM BY WILD-TYPE CYP2D6 PROTEIN AND A VARIANT CONTAINING METHIONINE, NOT VALINE, AT POSITION-374, Pharmacogenetics, 5(4), 1995, pp. 234-243
CYTOCHROMES P450 EXPRESSION SYSTEMS
Authors: GONZALEZ FJ KORZEKWA KR
Citation: Fj. Gonzalez et Kr. Korzekwa, CYTOCHROMES P450 EXPRESSION SYSTEMS, Annual review of pharmacology and toxicology, 35, 1995, pp. 369-390
ISOTOPE EFFECT STUDIES ON THE CYTOCHROME-P450 ENZYMES
Authors: KORZEKWA KR GILLETTE JR TRAGER WF
Citation: Kr. Korzekwa et al., ISOTOPE EFFECT STUDIES ON THE CYTOCHROME-P450 ENZYMES, Drug metabolism reviews, 27(1-2), 1995, pp. 45-59
CDNA-DIRECTED EXPRESSION OF HUMAN CYTOCHROME-P450 CYP1A1 USING BACULOVIRUS - PURIFICATION, DEPENDENCY ON NADPH-P450 OXIDOREDUCTASE, AND RECONSTITUTION OF CATALYTIC PROPERTIES WITHOUT PURIFICATION
Authors: BUTERS JTM SHOU MG HARDWICK JP KORZEKWA KR GONZALEZ FJ
Citation: Jtm. Buters et al., CDNA-DIRECTED EXPRESSION OF HUMAN CYTOCHROME-P450 CYP1A1 USING BACULOVIRUS - PURIFICATION, DEPENDENCY ON NADPH-P450 OXIDOREDUCTASE, AND RECONSTITUTION OF CATALYTIC PROPERTIES WITHOUT PURIFICATION, Drug metabolism and disposition, 23(7), 1995, pp. 696-701
DESIGNING SAFER CHEMICALS - PREDICTING THE RATES OF METABOLISM OF HALOGENATED ALKANES
Authors: YIN HQ ANDERS MW KORZEKWA KR HIGGINS L THUMMEL KE KHARASCH ED JONES JP
Citation: Hq. Yin et al., DESIGNING SAFER CHEMICALS - PREDICTING THE RATES OF METABOLISM OF HALOGENATED ALKANES, Proceedings of the National Academy of Sciences of the United Statesof America, 92(24), 1995, pp. 11076-11080
FLURBIPROFEN 4'-HYDROXYLATION BY CYP2C9
Authors: TRACY TS ROSENBLUTH BW WRIGHTON SA GONZALEZ FJ KORZEKWA KR
Citation: Ts. Tracy et al., FLURBIPROFEN 4'-HYDROXYLATION BY CYP2C9, Clinical pharmacology and therapeutics, 57(2), 1995, pp. 152-152
CYP4 ISOZYME SPECIFICITY AND THE RELATIONSHIP BETWEEN OMEGA-HYDROXYLATION AND TERMINAL DESATURATION OF VALPROIC ACID
Authors: RETTIE AE SHEFFELS PR KORZEKWA KR GONZALEZ FJ PHILPOT RM BAILLIE TA
Citation: Ae. Rettie et al., CYP4 ISOZYME SPECIFICITY AND THE RELATIONSHIP BETWEEN OMEGA-HYDROXYLATION AND TERMINAL DESATURATION OF VALPROIC ACID, Biochemistry, 34(24), 1995, pp. 7889-7895
STEREOSPECIFIC ACTIVATION OF THE PROCARCINOGEN BENZO[ALPHA]PYRENE - APROBE FOR THE ACTIVE-SITES OF THE CYTOCHROME-P450 SUPERFAMILY
Authors: JONES JP SHOU MG KORZEKWA KR
Citation: Jp. Jones et al., STEREOSPECIFIC ACTIVATION OF THE PROCARCINOGEN BENZO[ALPHA]PYRENE - APROBE FOR THE ACTIVE-SITES OF THE CYTOCHROME-P450 SUPERFAMILY, Biochemistry, 34(21), 1995, pp. 6956-6961
HUMAN LIVER OXIDATIVE-METABOLISM OF O-6-BENZYLGUANINE
Authors: ROY SK KORZEKWA KR GONZALEZ FJ MOSCHEL RC DOLAN ME
Citation: Sk. Roy et al., HUMAN LIVER OXIDATIVE-METABOLISM OF O-6-BENZYLGUANINE, Biochemical pharmacology, 50(9), 1995, pp. 1385-1389
Risultati: 1-25 | 26-42