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Results: 1-9 |
Results: 9
Development of potent and selective factor Xa inhibitors
Authors: Rai, R Kolesnikov, A Li, Y Young, WB Leahy, E Sprengeler, PA Verner, E Shrader, WD Burgess-Henry, J Sangalang, JC Allen, D Chen, X Katz, BA Luong, C Elrod, K Cregar, L
Citation: R. Rai et al., Development of potent and selective factor Xa inhibitors, BIOORG MED, 11(14), 2001, pp. 1797-1800
A novel serine protease inhibition motif involving a multi-centered short hydrogen bonding network at the active site
Authors: Katz, BA Elrod, K Luong, C Rice, MJ Mackman, RL Sprengeler, PA Spencer, J Hataye, J Janc, J Link, J Litvak, J Rai, R Rice, K Sideris, S Verner, E Young, W
Citation: Ba. Katz et al., A novel serine protease inhibition motif involving a multi-centered short hydrogen bonding network at the active site, J MOL BIOL, 307(5), 2001, pp. 1451-1486
Exploiting subsite S1 of trypsin-like serine proteases for selectivity: Potent and selective inhibitors of urokinase-type plasminogen activator
Authors: Mackman, RL Katz, BA Breitenbucher, JG Hui, HC Verner, E Luong, C Liu, L Sprengeler, PA
Citation: Rl. Mackman et al., Exploiting subsite S1 of trypsin-like serine proteases for selectivity: Potent and selective inhibitors of urokinase-type plasminogen activator, J MED CHEM, 44(23), 2001, pp. 3856-3871
Development of serine protease inhibitors displaying a multicentered short(< 2.3 angstrom) hydrogen bond binding mode: Inhibitors of urokinase-type plasminogen activator and factor Xa
Authors: Verner, E Katz, BA Spencer, JR Allen, D Hataye, J Hruzewicz, W Hui, HC Kolesnikov, A Li, Y Luong, C Martelli, A Radika, K Rai, R She, M Shrader, W Sprengeler, PA Trapp, S Wang, J Young, WB Mackman, RL
Citation: E. Verner et al., Development of serine protease inhibitors displaying a multicentered short(< 2.3 angstrom) hydrogen bond binding mode: Inhibitors of urokinase-type plasminogen activator and factor Xa, J MED CHEM, 44(17), 2001, pp. 2753-2771
Structural basis for selectivity of a small molecule, S1-binding, submicromolar inhibitor of urokinase-type plasminogen activator
Authors: Katz, BA Mackman, R Luong, C Radika, K Martelli, A Sprengeler, PA Wang, J Chan, HD Wong, L
Citation: Ba. Katz et al., Structural basis for selectivity of a small molecule, S1-binding, submicromolar inhibitor of urokinase-type plasminogen activator, CHEM BIOL, 7(4), 2000, pp. 299-312
A novel approach to serine protease inhibition: Kinetic characterization of inhibitors whose potencies and selectivities are dramatically enhanced byzinc(II)
Authors: Janc, JW Clark, JM Warne, RL Elrod, KC Katz, BA Moore, WR
Citation: Jw. Janc et al., A novel approach to serine protease inhibition: Kinetic characterization of inhibitors whose potencies and selectivities are dramatically enhanced byzinc(II), BIOCHEM, 39(16), 2000, pp. 4792-4800
Streptavidin-binding and -dimerizing ligands discovered by phage display, topochemistry, and structure-based design
Authors: Katz, BA
Citation: Ba. Katz, Streptavidin-binding and -dimerizing ligands discovered by phage display, topochemistry, and structure-based design, BIOMOL ENG, 16(1-4), 1999, pp. 57-65
Engineering a soluble extracellular erythropoietin receptor (EPObp) in Pichia pastoris to eliminate microheterogeneity, and its complex with erythropoietin
Authors: Zhan, HJ Liu, BS Reid, SW Aoki, KH Li, CW Syed, RS Karkaria, C Koe, G Sitney, K Hayenga, K Mistry, F Savel, L Dreyer, M Katz, BA Schreurs, J Matthews, DJ Cheetham, JC Egrie, J Giebel, LB Stroud, RM
Citation: Hj. Zhan et al., Engineering a soluble extracellular erythropoietin receptor (EPObp) in Pichia pastoris to eliminate microheterogeneity, and its complex with erythropoietin, PROTEIN ENG, 12(6), 1999, pp. 505-513
Recruiting Zn2+ to mediate potent, specific inhibition of serine proteases
Authors: Katz, BA Luong, C
Citation: Ba. Katz et C. Luong, Recruiting Zn2+ to mediate potent, specific inhibition of serine proteases, J MOL BIOL, 292(3), 1999, pp. 669-684
Risultati: 1-9 |