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Results: 1-25 | 26-40
Results: 1-25/40
Synergy of the protein farnesyltransferase inhibitor SCH66336 and cisplatin in human cancer cell lines
Authors: Adjei, AA Davis, JN Bruzek, LM Erlichman, C Kaufmann, SH
Citation: Aa. Adjei et al., Synergy of the protein farnesyltransferase inhibitor SCH66336 and cisplatin in human cancer cell lines, CLIN CANC R, 7(5), 2001, pp. 1438-1445
Apoptosis and the response to anticancer therapy
Authors: Mow, BMF Blajeski, AL Chandra, J Kaufmann, SH
Citation: Bmf. Mow et al., Apoptosis and the response to anticancer therapy, CURR OPIN O, 13(6), 2001, pp. 453-462
Current status of clinical trials of farnesyltransferase inhibitors
Authors: Karp, JE Kaufmann, SH Adjei, AA Lancet, JE Wright, JJ End, DW
Citation: Je. Karp et al., Current status of clinical trials of farnesyltransferase inhibitors, CURR OPIN O, 13(6), 2001, pp. 470-476
Programmed cell death: alive and well in the new millennium
Authors: Kaufmann, SH Hengartner, MO
Citation: Sh. Kaufmann et Mo. Hengartner, Programmed cell death: alive and well in the new millennium, TR CELL BIO, 11(12), 2001, pp. 526-534
Phase I trial of gemcitabine and CPT-11 given weekly for four weeks every six weeks
Authors: Alberts, SR Erlichman, C Sloan, J Okuno, SH Burch, PA Rubin, J Pitot, HC Goldberg, RM Adjei, AA Atherton, PJ Kaufmann, SH
Citation: Sr. Alberts et al., Phase I trial of gemcitabine and CPT-11 given weekly for four weeks every six weeks, ANN ONCOL, 12(5), 2001, pp. 627-631
Is TRAIL hepatotoxic?
Authors: Gores, GJ Kaufmann, SH
Citation: Gj. Gores et Sh. Kaufmann, Is TRAIL hepatotoxic?, HEPATOLOGY, 34(1), 2001, pp. 3-6
Caspases 3 and 9 send a pro-apoptotic signal from synapse to cell body in olfactory receptor neurons
Authors: Cowan, CM Thai, J Krajewski, S Reed, JC Nicholson, DW Kaufmann, SH Roskams, AJ
Citation: Cm. Cowan et al., Caspases 3 and 9 send a pro-apoptotic signal from synapse to cell body in olfactory receptor neurons, J NEUROSC, 21(18), 2001, pp. 7099-7109
A multistep model for paclitaxel-induced apoptosis in human breast cancer cell lines
Authors: Blajeski, AL Kottke, TJ Kaufmann, SH
Citation: Al. Blajeski et al., A multistep model for paclitaxel-induced apoptosis in human breast cancer cell lines, EXP CELL RE, 270(2), 2001, pp. 277-288
Human INCENP colocalizes with the Aurora-B/AIRK2 kinase on chromosomes andis overexpressed in tumour cells
Authors: Adams, RR Eckley, DM Vagnarelli, P Wheatley, SP Gerloff, DL Mackay, AM Svingen, PA Kaufmann, SH Earnshaw, WC
Citation: Rr. Adams et al., Human INCENP colocalizes with the Aurora-B/AIRK2 kinase on chromosomes andis overexpressed in tumour cells, CHROMOSOMA, 110(2), 2001, pp. 65-74
The HER tyrosine kinase inhibitor CI1033 enhances cytotoxicity of 7-ethyl-10-hydroxycamptothecin and topotecan by inhibiting breast cancer resistanceprotein-mediated drug efflux
Authors: Erlichman, C Boerner, SA Hallgren, CG Spieker, R Wang, XY James, CD Scheffer, GL Maliepaard, M Ross, DD Bible, KC Kaufmann, SH
Citation: C. Erlichman et al., The HER tyrosine kinase inhibitor CI1033 enhances cytotoxicity of 7-ethyl-10-hydroxycamptothecin and topotecan by inhibiting breast cancer resistanceprotein-mediated drug efflux, CANCER RES, 61(2), 2001, pp. 739-748
Loss of expression of a new member of the DNAJ protein family confers resistance to chemotherapeutic agents used in the treatment of ovarian cancer
Authors: Shridhar, V Bible, KC Staub, J Avula, R Lee, YK Kalli, K Huang, HJ Hartmann, LC Kaufmann, SH Smith, DI
Citation: V. Shridhar et al., Loss of expression of a new member of the DNAJ protein family confers resistance to chemotherapeutic agents used in the treatment of ovarian cancer, CANCER RES, 61(10), 2001, pp. 4258-4265
Effect of P-glycoprotein on flavopiridol sensitivity
Authors: Boerner, SA Tourne, ME Kaufmann, SH Bible, KC
Citation: Sa. Boerner et al., Effect of P-glycoprotein on flavopiridol sensitivity, BR J CANC, 84(10), 2001, pp. 1391-1396
Enhanced ceramide generation and induction of apoptosis in human leukemia cells exposed to DT388-granulocyte-macrophage colony-stimulating factor (GM-CSF), a truncated diphtheria toxin fused to human GM-CSF
Authors: Senchenkov, A Han, TY Wang, HT Frankel, AE Kottke, TJ Kaufmann, SH Cabot, MC
Citation: A. Senchenkov et al., Enhanced ceramide generation and induction of apoptosis in human leukemia cells exposed to DT388-granulocyte-macrophage colony-stimulating factor (GM-CSF), a truncated diphtheria toxin fused to human GM-CSF, BLOOD, 98(6), 2001, pp. 1927-1934
Clinical and biologic activity of the farnesyltransferase inhibitor R115777 in adults with refractory and relapsed acute leukemias: a phase 1 clinical-laboratory correlative trial
Authors: Karp, JE Lancet, JE Kaufmann, SH End, DW Wright, JJ Bol, K Horak, I Tidwell, ML Liesveld, J Kottke, TJ Ange, D Buddharaju, L Gojo, I Highsmith, WE Belly, RT Hohl, RJ Rybak, ME Thibault, A Rosenblatt, J
Citation: Je. Karp et al., Clinical and biologic activity of the farnesyltransferase inhibitor R115777 in adults with refractory and relapsed acute leukemias: a phase 1 clinical-laboratory correlative trial, BLOOD, 97(11), 2001, pp. 3361-3369
Reutilization of immunoblots after chemiluminescent detection
Authors: Kaufmann, SH
Citation: Sh. Kaufmann, Reutilization of immunoblots after chemiluminescent detection, ANALYT BIOC, 296(2), 2001, pp. 283-286
Comparison of potential markers of farnesyltransferase inhibition
Authors: Adjei, AA Davis, JN Erlichman, C Svingen, PA Kaufmann, SH
Citation: Aa. Adjei et al., Comparison of potential markers of farnesyltransferase inhibition, CLIN CANC R, 6(6), 2000, pp. 2318-2325
Characterization of an ovarian carcinoma cell line resistant to cisplatin and flavopiridol
Authors: Bible, KC Boerner, SA Kirkland, K Anderl, KL Bartelt, D Svingen, PA Kottke, TJ Lee, YK Eckdahl, S Stalboerger, PG Jenkins, RB Kaufmann, SH
Citation: Kc. Bible et al., Characterization of an ovarian carcinoma cell line resistant to cisplatin and flavopiridol, CLIN CANC R, 6(2), 2000, pp. 661-670
Induction of apoptosis in malignant B cells by phenylbutyrate or phenylacetate in combination with chemotherapeutic agents
Authors: Witzig, TE Timm, M Stenson, M Svingen, PA Kaufmann, SH
Citation: Te. Witzig et al., Induction of apoptosis in malignant B cells by phenylbutyrate or phenylacetate in combination with chemotherapeutic agents, CLIN CANC R, 6(2), 2000, pp. 681-692
Effect of the bcr/abl kinase inhibitors AG957 and NSC 680410 on chronic myelogenous leukemia cells in vitro
Authors: Svingen, PA Tefferi, A Kottke, TJ Kaur, G Narayanan, VL Sausville, EA Kaufmann, SH
Citation: Pa. Svingen et al., Effect of the bcr/abl kinase inhibitors AG957 and NSC 680410 on chronic myelogenous leukemia cells in vitro, CLIN CANC R, 6(1), 2000, pp. 237-249
Apoptosis in cancer: cause and cure
Authors: Kaufmann, SH Gores, GJ
Citation: Sh. Kaufmann et Gj. Gores, Apoptosis in cancer: cause and cure, BIOESSAYS, 22(11), 2000, pp. 1007-1017
Detection of DNA cleavage in apoptotic cells
Authors: Kaufmann, SH Mesner, PW Samejima, K Tone, S Earnshaw, WC
Citation: Sh. Kaufmann et al., Detection of DNA cleavage in apoptotic cells, METH ENZYM, 322, 2000, pp. 3
Effect of 6-aminonicotinamide and other protein synthesis inhibitors on formation of platinum-DNA adducts and cisplatin sensitivity
Authors: Budihardjo, II Boerner, SA Eckdahl, S Svingen, PA Rios, R Ames, MM Kaufmann, SH
Citation: Ii. Budihardjo et al., Effect of 6-aminonicotinamide and other protein synthesis inhibitors on formation of platinum-DNA adducts and cisplatin sensitivity, MOLEC PHARM, 57(3), 2000, pp. 529-538
Successful virtual screening of a chemical database for farnesyltransferase inhibitor leads
Authors: Perola, E Xu, K Kollmeyer, TM Kaufmann, SH Prendergast, FG Pang, YP
Citation: E. Perola et al., Successful virtual screening of a chemical database for farnesyltransferase inhibitor leads, J MED CHEM, 43(3), 2000, pp. 401-408
Cathepsin B contributes to TNF-alpha-mediated hepatocyte apoptosis by promoting mitochondrial release of cytochrome c
Authors: Guicciardi, ME Deussing, J Miyoshi, H Bronk, SF Svingen, PA Peters, C Kaufmann, SH Gores, GJ
Citation: Me. Guicciardi et al., Cathepsin B contributes to TNF-alpha-mediated hepatocyte apoptosis by promoting mitochondrial release of cytochrome c, J CLIN INV, 106(9), 2000, pp. 1127-1137
BRCA1 facilitates stress-induced apoptosis in breast and ovarian cancer cell lines
Authors: Thangaraju, M Kaufmann, SH Couch, FJ
Citation: M. Thangaraju et al., BRCA1 facilitates stress-induced apoptosis in breast and ovarian cancer cell lines, J BIOL CHEM, 275(43), 2000, pp. 33487-33496
Risultati: 1-25 | 26-40