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Results: 1-15 |
Results: 15
Population pharmacokinetics of ifosfamide and its 2-and 3-dechloroethylated and 4-hydroxylated metabolites in resistant small-cell lung cancer patients
Authors: Kerbusch, T vanPutten, JWG Groen, HJM Huitema, ADR Mathot, RAA Beijnen, JH
Citation: T. Kerbusch et al., Population pharmacokinetics of ifosfamide and its 2-and 3-dechloroethylated and 4-hydroxylated metabolites in resistant small-cell lung cancer patients, CANC CHEMOT, 48(1), 2001, pp. 53-61
Population pharmacokinetics of ifosfamide and its dechloroethylated and hydroxylated metabolites in children with malignant disease - A sparse sampling approach
Authors: Kerbusch, T de Kraker, J Mathot, RAA Beijnen, JH
Citation: T. Kerbusch et al., Population pharmacokinetics of ifosfamide and its dechloroethylated and hydroxylated metabolites in children with malignant disease - A sparse sampling approach, CLIN PHARMA, 40(8), 2001, pp. 615-625
Clinical pharmacokinetics and pharmacodynamics of ifosfamide and its metabolites
Authors: Kerbusch, T de Kraker, J Keizer, HJ van Putten, JWG Groen, HJM Jansen, RLH Schellens, JHM Beijnen, JH
Citation: T. Kerbusch et al., Clinical pharmacokinetics and pharmacodynamics of ifosfamide and its metabolites, CLIN PHARMA, 40(1), 2001, pp. 41-62
Distribution of ifosfamide and metabolites between plasma and erythrocytes
Authors: Kerbusch, T Herben, VMM Jeuken, MJJ Ouwerkerk, J Keizer, HJ Beijnen, JH
Citation: T. Kerbusch et al., Distribution of ifosfamide and metabolites between plasma and erythrocytes, BIOPHARM DR, 22(3), 2001, pp. 99-108
Influence of dose and infusion duration on pharmacokinetics of ifosfamide and metabolites
Authors: Kerbusch, T Mathot, RAA Keizer, HJ Kaijser, GP Schellens, JHM Beijnen, JH
Citation: T. Kerbusch et al., Influence of dose and infusion duration on pharmacokinetics of ifosfamide and metabolites, DRUG META D, 29(7), 2001, pp. 967-975
Population pharmacokinetics and exploratory pharmacodynamics of ifosfamideand metabolites after a 72-h continuous infusion in patients with soft tissue sarcoma
Authors: Kerbusch, T Mathot, RAA Keizer, HJ Ouwerkerk, J Rodenhuis, S Schellens, JHM Beijnen, JH
Citation: T. Kerbusch et al., Population pharmacokinetics and exploratory pharmacodynamics of ifosfamideand metabolites after a 72-h continuous infusion in patients with soft tissue sarcoma, EUR J CL PH, 57(6-7), 2001, pp. 467-477
Modulation of the cytochrome P450-mediated metabolism of ifosfamide by ketoconazole and rifampin
Authors: Kerbusch, T Jansen, RLH Mathot, RAA Huitema, ADR Jansen, M van Rijswijk, REN Beijnen, JH
Citation: T. Kerbusch et al., Modulation of the cytochrome P450-mediated metabolism of ifosfamide by ketoconazole and rifampin, CLIN PHARM, 70(2), 2001, pp. 132-141
Simple and selective determination of the cyclophosphamide metabolite phosphoramide mustard in human plasma using high-performance liquid chromatography
Authors: Huitema, ADR Tibben, MM Kerbusch, T Kettenes-van den Bosch, JJ Rodenhuis, S Beijnen, JH
Citation: Adr. Huitema et al., Simple and selective determination of the cyclophosphamide metabolite phosphoramide mustard in human plasma using high-performance liquid chromatography, J CHROMAT B, 745(2), 2000, pp. 345-355
Simultaneous determination of ifosfamide and its metabolite ifosforamide mustard in human plasma by high performance liquid chromatography
Authors: Kerbusch, T Huitema, ADR Jeuken, MJJ Derraz, J Tibben, MM Beijnen, JH
Citation: T. Kerbusch et al., Simultaneous determination of ifosfamide and its metabolite ifosforamide mustard in human plasma by high performance liquid chromatography, J LIQ CHR R, 23(19), 2000, pp. 2991-3010
High performance liquid chromatographic determination of the stabilized cyclophosphamide metabolite 4-hydroxycyclophosphamide in plasma and red bloodcells
Authors: Huitema, ADR Tibben, MM Kerbusch, T Kettenes-van den Bosch, JJ Rodenhuis, S Beijnen, JH
Citation: Adr. Huitema et al., High performance liquid chromatographic determination of the stabilized cyclophosphamide metabolite 4-hydroxycyclophosphamide in plasma and red bloodcells, J LIQ CHR R, 23(11), 2000, pp. 1725-1744
Reduction of cyclophosphamide bioactivation by thioTEPA: critical sequence-dependency in high-dose chemotherapy regimens
Authors: Huitema, ADR Kerbusch, T Tibben, MM Rodenhuis, S Beijnen, JH
Citation: Adr. Huitema et al., Reduction of cyclophosphamide bioactivation by thioTEPA: critical sequence-dependency in high-dose chemotherapy regimens, CANC CHEMOT, 46(2), 2000, pp. 119-127
Evaluation of the autoinduction of ifosfamide metabolism by a population pharmacokinetic approach using NONMEM
Authors: Kerbusch, T Huitema, ADR Ouwerkerk, J Keizer, HJ Mathot, RAA Schellens, JHM Beijnen, JH
Citation: T. Kerbusch et al., Evaluation of the autoinduction of ifosfamide metabolism by a population pharmacokinetic approach using NONMEM, BR J CL PH, 49(6), 2000, pp. 555-561
Studies on the mechanism of a fatal clarithromycin-pimozide interaction ina patient with Tourette syndrome
Authors: Flockhart, DA Drici, MD Kerbusch, T Soukhova, N Richard, E Pearle, PL Mahal, SK Babb, VJ
Citation: Da. Flockhart et al., Studies on the mechanism of a fatal clarithromycin-pimozide interaction ina patient with Tourette syndrome, J CL PSYCH, 20(3), 2000, pp. 317-324
Determination of ifosfamide, 2-and 3-dechloroethyifosfamide using gas chromatography with nitrogen-phosphorus or mass spectrometry detection
Authors: Kerbusch, T Jeuken, MJ Derraz, J van Putten, JWG Huitema, ADR Beijnen, JH
Citation: T. Kerbusch et al., Determination of ifosfamide, 2-and 3-dechloroethyifosfamide using gas chromatography with nitrogen-phosphorus or mass spectrometry detection, THER DRUG M, 22(5), 2000, pp. 613-620
Effect of clarithromycin on the pharmacokinetics and pharmacodynamics of pimozide in healthy poor and extensive metabolizers of cytochrome P450 2D6 (CYP2D6)
Authors: Desta, Z Kerbusch, T Flockhart, DA
Citation: Z. Desta et al., Effect of clarithromycin on the pharmacokinetics and pharmacodynamics of pimozide in healthy poor and extensive metabolizers of cytochrome P450 2D6 (CYP2D6), CLIN PHARM, 65(1), 1999, pp. 10-20
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