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Results:
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Results: 25
Authors:
Tweedy, CM
Milgrom, P
Kharasch, ED
Kaakko, T
Spieker, M
Coldwell, SE
Citation: Cm. Tweedy et al., Pharmacokinetics and clinical effects of sublingual triazolam in pediatricdental patients, J CL PSYCH, 21(3), 2001, pp. 268-272
Authors:
Oda, Y
Kharasch, ED
Citation: Y. Oda et Ed. Kharasch, Metabolism of methadone and levo-alpha-acetylmethadol (LAAM) by human intestinal cytochrome P450 3A4 (CYP3A4): Potential contribution of intestinal metabolism to presysternic clearance and bioactivation, J PHARM EXP, 298(3), 2001, pp. 1021-1032
Authors:
Oda, Y
Kharasch, ED
Citation: Y. Oda et Ed. Kharasch, Metabolism of levo-alpha-acetylmethadol (LAAM) by human liver cytochrome P450: Involvement of CYP3A4 characterized by atypical kinetics with two binding sites, J PHARM EXP, 297(1), 2001, pp. 410-422
Authors:
Yao, CP
Kunze, KL
Kharasch, ED
Wang, Y
Trager, WF
Ragueneau, I
Levy, RH
Citation: Cp. Yao et al., Fluvoxamine-theophylline interaction: Gap between in vitro and in vivo inhibition constants toward cytochrome P4501A2, CLIN PHARM, 70(5), 2001, pp. 415-424
Authors:
Ibrahim, AE
Taraday, JK
Kharasch, ED
Citation: Ae. Ibrahim et al., Bispectral Index Monitoring during Sedation with Sevoflurane, Midazolam, and Propofol, ANESTHESIOL, 95(5), 2001, pp. 1151-1159
Authors:
Minoda, Y
Kharasch, ED
Citation: Y. Minoda et Ed. Kharasch, Halothane-dependent lipid peroxidation in human liver microsomes is catalyzed by cytochrome P4502A6 (CYP2A6), ANESTHESIOL, 95(2), 2001, pp. 509-514
Authors:
Ibrahim, AE
Ghoneim, MM
Kharasch, ED
Epstein, RH
Groudine, SB
Ebert, TJ
Binstock, WB
Philip, BK
Citation: Ae. Ibrahim et al., Speed of recovery and side-effect profile of sevoflurane sedation comparedwith midazolam, ANESTHESIOL, 94(1), 2001, pp. 87-94
Long-duration low-flow sevoflurane and lsoflurane effects on postoperativerenal and hepatic function
Authors:
Kharasch, ED
Frink, EJ
Artru, A
Michalowski, P
Rooke, GA
Nogami, W
Citation: Ed. Kharasch et al., Long-duration low-flow sevoflurane and lsoflurane effects on postoperativerenal and hepatic function, ANESTH ANAL, 93(6), 2001, pp. 1511-1520
Authors:
Palmer, RB
Mautz, DS
Cox, K
Kharasch, ED
Citation: Rb. Palmer et al., Endotracheal lidocaine administration via an esophageal combitube, J EMERG MED, 18(2), 2000, pp. 153-157
Authors:
Kharasch, ED
Hankins, DC
Taraday, JK
Citation: Ed. Kharasch et al., Single-dose methoxsalen effects on human cytochrome P-450 2A6 activity, DRUG META D, 28(1), 2000, pp. 28-33
Authors:
Kharasch, ED
Hankins, DC
Fenstamaker, K
Cox, K
Citation: Ed. Kharasch et al., Human halothane metabolism, lipid peroxidation, and cytochromes P(450)2A6 and P(450)3A4, EUR J CL PH, 55(11-12), 2000, pp. 853-859
Authors:
Manyike, PT
Kharasch, ED
Kalhorn, TF
Slattery, JT
Citation: Pt. Manyike et al., Contribution of CYP2E1 and CYP3A to acetaminophen reactive metabolite formation, CLIN PHARM, 67(3), 2000, pp. 275-282
Authors:
Kharasch, ED
Jubert, C
Citation: Ed. Kharasch et C. Jubert, Compound A uptake and metabolism to mercapturic acids and 3,3,3-trifluoro-2-fluoromethoxypropanoic acid during low-flow sevoflurane anesthesia - Biomarkers for exposure, risk assessment, and interspecies comparison (vol 91, pg 1267, 1999), ANESTHESIOL, 92(1), 2000, pp. 297-297
Authors:
Kharasch, ED
Citation: Ed. Kharasch, Putting the brakes on anesthetic breakdown (vol 91, pg 1192, 1999), ANESTHESIOL, 92(1), 2000, pp. 297-297
Authors:
Kharasch, ED
Citation: Ed. Kharasch, Editorial view (vol 91, pg 1192, 1999), ANESTHESIOL, 92(1), 2000, pp. 297-297
Authors:
Davis, CL
Kausz, AT
Zager, RA
Kharasch, ED
Cochran, RP
Citation: Cl. Davis et al., Acute renal failure after cardiopulmonary bypass is related to decreased serum ferritin levels, J AM S NEPH, 10(11), 1999, pp. 2396-2402
Authors:
Groudine, SB
Fragen, RJ
Kharasch, ED
Eisenman, TS
Frink, EJ
McConnell, S
Citation: Sb. Groudine et al., Comparison of renal function following anesthesia with low-flow sevoflurane and isoflurane, J CLIN ANES, 11(3), 1999, pp. 201-207
Authors:
Kharasch, ED
Jubert, C
Senn, T
Bowdle, TA
Thummel, KE
Citation: Ed. Kharasch et al., Intraindividual variability in male hepatic CYP3A4 activity assessed by alfentanil and midazolam clearance, J CLIN PHAR, 39(7), 1999, pp. 664-669
Authors:
Kharasch, ED
Mautz, D
Senn, T
Lentz, G
Cox, K
Citation: Ed. Kharasch et al., Menstrual cycle variability in midazolam pharmacokinetics, J CLIN PHAR, 39(3), 1999, pp. 275-280
Authors:
Kharasch, ED
Hankins, DC
Jubert, C
Thummel, KE
Taraday, JK
Citation: Ed. Kharasch et al., Lack of single-dose disulfiram effects on cytochrome P-4502C9, 2C19, 2D6, and 3A4 activities: Evidence for specificity toward P-450 2E1, DRUG META D, 27(6), 1999, pp. 717-723
Authors:
Kharasch, ED
Jubert, C
Spracklin, DK
Hoffman, GM
Citation: Ed. Kharasch et al., Dose-dependent metabolism of fluoromethyl-2,2-difluoro-1-(trifluoromethyl)vinyl ether (Compound A), an anesthetic degradation product, to mercapturicacids and 3,3,3-trifluoro-2(fluoromethoxy)propanoic acid in rats, TOX APPL PH, 160(1), 1999, pp. 49-59
Authors:
Emery, MG
Jubert, C
Thummel, KE
Kharasch, ED
Citation: Mg. Emery et al., Duration of cytochrome P-450 2E1 (CYP2E1) inhibition and estimation of functional CYP2E1 enzyme half-life after single-dose disulfiram administrationin humans, J PHARM EXP, 291(1), 1999, pp. 213-219
Authors:
Kharasch, ED
Hankins, DC
Cox, K
Citation: Ed. Kharasch et al., Clinical isoflurane metabolism by cytochrome P450 2E1, ANESTHESIOL, 90(3), 1999, pp. 766-771
Authors:
Kharasch, ED
Hankins, D
Citation: Ed. Kharasch et D. Hankins, Renal cysteine conjugate beta-lyase and compound A nephrotoxicity: Minimalevidence for an association - Reply, ANESTHESIOL, 90(3), 1999, pp. 921-922
Authors:
Kharasch, ED
Citation: Ed. Kharasch, Compound A: toxicology and clinical importance, ANAESTHESIS, 47, 1998, pp. S7-S10
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