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The lung as a route for systemic delivery of therapeutic proteins and peptides
Authors: Agu, RU Ugwoke, MI Armand, M Kinget, R Verbeke, N
Citation: Ru. Agu et al., The lung as a route for systemic delivery of therapeutic proteins and peptides, RESPIR RES, 2(4), 2001, pp. 198-209
Physical stabilisation of amorphous ketoconazole in solid dispersions withpolyvinylpyrrolidone K25
Authors: Van den Mooter, G Wuyts, M Blaton, N Busson, R Grobet, P Augustijns, P Kinget, R
Citation: G. Van Den Mooter et al., Physical stabilisation of amorphous ketoconazole in solid dispersions withpolyvinylpyrrolidone K25, EUR J PH SC, 12(3), 2001, pp. 261-269
Determination of partial solubility parameters of five benzodiazepines in individual solvents
Authors: Verheyen, S Augustijns, P Kinget, R Van den Mooter, G
Citation: S. Verheyen et al., Determination of partial solubility parameters of five benzodiazepines in individual solvents, INT J PHARM, 228(1-2), 2001, pp. 199-207
Synthesis and characterisation of inulin-azo hydrogels designed for colon targeting
Authors: Maris, B Verheyden, L Van Reeth, K Samyn, C Augustijns, P Kinget, R Van den Mooter, G
Citation: B. Maris et al., Synthesis and characterisation of inulin-azo hydrogels designed for colon targeting, INT J PHARM, 213(1-2), 2001, pp. 143-152
Characterization of glassy itraconazole: a comparative study of its molecular mobility below T-g with that of structural analogues using MTDSC
Authors: Six, K Verreck, G Peeters, J Augustijns, P Kinget, R Van den Mooter, G
Citation: K. Six et al., Characterization of glassy itraconazole: a comparative study of its molecular mobility below T-g with that of structural analogues using MTDSC, INT J PHARM, 213(1-2), 2001, pp. 163-173
Melting behavior of pure polyethylene glycol 6000 and polyethylene glycol 6000 in solid dispersions containing diazepam or temazepam: a DSC study
Authors: Verheyen, S Augustijns, P Kinget, R Van den Mooter, G
Citation: S. Verheyen et al., Melting behavior of pure polyethylene glycol 6000 and polyethylene glycol 6000 in solid dispersions containing diazepam or temazepam: a DSC study, THERMOC ACT, 380(2), 2001, pp. 153-164
Investigation of thermal properties of glassy itraconazole: identificationof a monotropic mesophase
Authors: Six, K Verreck, G Peeters, J Binnemans, K Berghmans, H Augustijns, P Kinget, R Van den Mooter, G
Citation: K. Six et al., Investigation of thermal properties of glassy itraconazole: identificationof a monotropic mesophase, THERMOC ACT, 376(2), 2001, pp. 175-181
Thermal characterization of the antiviral drug UC-781 and stability of itsglass
Authors: Damian, F Blaton, N Augustijns, P Naesens, L Balzarini, J Kinget, R Van den Mooter, G
Citation: F. Damian et al., Thermal characterization of the antiviral drug UC-781 and stability of itsglass, THERMOC ACT, 366(1), 2001, pp. 61-69
Solid state properties of pure UC-781 and solid dispersions with polyvinylpyrrolidone (PVP K30)
Authors: Damian, F Blaton, N Desseyn, H Clou, K Augustijns, P Naesens, L Balzarini, J Kinget, R Van den Mooter, G
Citation: F. Damian et al., Solid state properties of pure UC-781 and solid dispersions with polyvinylpyrrolidone (PVP K30), J PHARM PHA, 53(8), 2001, pp. 1109-1116
In-vitro nasal drug delivery studies: comparison of derivatised, fibrillarand polymerised collagen matrix-based human nasal primary culture systems for nasal drug delivery studies
Authors: Agu, RU Jorissen, M Willems, T Augustijns, P Kinget, R Verbeke, N
Citation: Ru. Agu et al., In-vitro nasal drug delivery studies: comparison of derivatised, fibrillarand polymerised collagen matrix-based human nasal primary culture systems for nasal drug delivery studies, J PHARM PHA, 53(11), 2001, pp. 1447-1456
The biopharmaceutical aspects of nasal mucoadhesive drug delivery
Authors: Ugwoke, MI Verbeke, N Kinget, R
Citation: Mi. Ugwoke et al., The biopharmaceutical aspects of nasal mucoadhesive drug delivery, J PHARM PHA, 53(1), 2001, pp. 3-21
New bis(SATE) prodrug of AZT 5 '-monophosphate: In vitro anti-HIV activity, stability, and potential oral absorption
Authors: Shafiee, M Deferme, S Villard, AL Egron, D Gosselin, G Imbach, JL Lioux, T Pompon, A Varray, S Aubertin, AM Van den Mooter, G Kinget, R Perigaud, C Augustijns, P
Citation: M. Shafiee et al., New bis(SATE) prodrug of AZT 5 '-monophosphate: In vitro anti-HIV activity, stability, and potential oral absorption, J PHARM SCI, 90(4), 2001, pp. 448-463
Nasal toxicological investigations of Carbopol 971P formulation of apomorphine: effects on ciliary beat frequency of human nasal primary cell cultureand in vivo on rabbit nasal mucosa
Authors: Ugwoke, MI Agu, RU Jorissen, M Augustijns, P Sciot, R Verbeke, N Kinget, R
Citation: Mi. Ugwoke et al., Nasal toxicological investigations of Carbopol 971P formulation of apomorphine: effects on ciliary beat frequency of human nasal primary cell cultureand in vivo on rabbit nasal mucosa, EUR J PH SC, 9(4), 2000, pp. 387-396
Physicochemical characterization of solid dispersions of the antiviral agent UC-781 with polyethylene glycol 6000 and Gelucire 44/14
Authors: Damian, F Blaton, N Naesens, L Balzarini, J Kinget, R Augustijns, P Van den Mooter, G
Citation: F. Damian et al., Physicochemical characterization of solid dispersions of the antiviral agent UC-781 with polyethylene glycol 6000 and Gelucire 44/14, EUR J PH SC, 10(4), 2000, pp. 311-322
Toxicological investigations of the effects carboxymethylcellulose on ciliary beat frequency of human nasal epithelial cells in primary suspension culture and in vivo on rabbit nasal mucosa
Authors: Ugwoke, MI Agu, RU Jorissen, M Augustijns, P Sciot, R Verbeke, N Kinget, R
Citation: Mi. Ugwoke et al., Toxicological investigations of the effects carboxymethylcellulose on ciliary beat frequency of human nasal epithelial cells in primary suspension culture and in vivo on rabbit nasal mucosa, INT J PHARM, 205(1-2), 2000, pp. 43-51
Species-dependent and site-specific intestinal metabolism of ester prodrugs
Authors: Van Gelder, J Shafiee, M De Clercq, E Penninckx, F Van den Mooter, G Kinget, R Augustijns, P
Citation: J. Van Gelder et al., Species-dependent and site-specific intestinal metabolism of ester prodrugs, INT J PHARM, 205(1-2), 2000, pp. 93-100
Intranasal bioavailability of apomorphine from carboxymethylcellulose-based drug delivery systems
Authors: Ugwoke, MI Kaufmann, G Verbeke, N Kinget, R
Citation: Mi. Ugwoke et al., Intranasal bioavailability of apomorphine from carboxymethylcellulose-based drug delivery systems, INT J PHARM, 202(1-2), 2000, pp. 125-131
Safety assessment of selected cyclodextrins - effect on ciliary activity using a human cell suspension culture model exhibiting in vitro ciliogenesis
Authors: Agu, RU Jorissen, M Willems, T Van den Mooter, G Kinget, R Verbeke, N Augustijns, P
Citation: Ru. Agu et al., Safety assessment of selected cyclodextrins - effect on ciliary activity using a human cell suspension culture model exhibiting in vitro ciliogenesis, INT J PHARM, 193(2), 2000, pp. 219-226
Scintigraphic evaluation in rabbits of nasal drug delivery systems based on carbopol 971p (R) and carboxymethylcellulose
Authors: Ugwoke, MI Agu, RU Vanbilloen, H Baetens, J Augustijns, P Verbeke, N Mortelmans, L Verbruggen, A Kinget, R Bormans, G
Citation: Mi. Ugwoke et al., Scintigraphic evaluation in rabbits of nasal drug delivery systems based on carbopol 971p (R) and carboxymethylcellulose, J CONTR REL, 68(2), 2000, pp. 207-214
Increased absorption of the antiviral ester prodrug tenofovir disoproxil in rat ileum by inhibiting its intestinal metabolism
Authors: Van Gelder, J Deferme, S Annaert, P Naesens, L De Clercq, E Van den Mooter, G Kinget, R Augustijns, P
Citation: J. Van Gelder et al., Increased absorption of the antiviral ester prodrug tenofovir disoproxil in rat ileum by inhibiting its intestinal metabolism, DRUG META D, 28(12), 2000, pp. 1394-1396
In vitro, ex vivo, and in situ intestinal absorption characteristics of the antiviral ester prodrug adefovir dipivoxil
Authors: Annaert, P Tukker, JJ Van Gelder, J Naesens, L De Clercq, E Van den Mooter, G Kinget, R Augustijns, P
Citation: P. Annaert et al., In vitro, ex vivo, and in situ intestinal absorption characteristics of the antiviral ester prodrug adefovir dipivoxil, J PHARM SCI, 89(8), 2000, pp. 1054-1062
Glass forming properties of benzodiazepines and co-evaporate systems with poly(hydroxyethyl methacrylate)
Authors: Van den Mooter, G Van den Brande, J Augustijns, P Kinget, R
Citation: G. Van Den Mooter et al., Glass forming properties of benzodiazepines and co-evaporate systems with poly(hydroxyethyl methacrylate), J THERM ANA, 57(2), 1999, pp. 493-507
Bioavailability of apomorphine following intranasal administration of mucoadhesive drug delivery systems in rabbits
Authors: Ugwoke, MI Exaud, S Van Den Mooter, G Verbeke, N Kinget, R
Citation: Mi. Ugwoke et al., Bioavailability of apomorphine following intranasal administration of mucoadhesive drug delivery systems in rabbits, EUR J PH SC, 9(2), 1999, pp. 213-219
Effects of pharmaceutical compounds on ciliary beating in human nasal epithelial cells: A comparative study of cell culture models
Authors: Agu, RU Jorissen, M Willems, T Van den Mooter, G Kinget, R Augustijns, P
Citation: Ru. Agu et al., Effects of pharmaceutical compounds on ciliary beating in human nasal epithelial cells: A comparative study of cell culture models, PHARM RES, 16(9), 1999, pp. 1380-1385
Inhibition of intestinal metabolism of the antiviral ester prodrug bis(POC)-PMPA by nature-identical fruit extracts as a strategy to enhance its oralabsorption: An in vitro study
Authors: Van Gelder, J Annaert, P Naesens, L De Clercq, E Van den Mooter, G Kinget, R Augustijns, P
Citation: J. Van Gelder et al., Inhibition of intestinal metabolism of the antiviral ester prodrug bis(POC)-PMPA by nature-identical fruit extracts as a strategy to enhance its oralabsorption: An in vitro study, PHARM RES, 16(7), 1999, pp. 1035-1040
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